KEGG   Corynebacterium diphtheriae PW8: CDPW8_0364
Entry
CDPW8_0364        CDS       T01701                                 
Symbol
rmlD
Name
(GenBank) dTDP-4-dehydrorhamnose reductase
  KO
K23987  dTDP-4-dehydrorhamnose 3,5-epimerase/reductase [EC:5.1.3.13 1.1.1.133]
Organism
cdw  Corynebacterium diphtheriae PW8
Pathway
cdw00521  Streptomycin biosynthesis
cdw00523  Polyketide sugar unit biosynthesis
cdw00541  Biosynthesis of various nucleotide sugars
cdw01100  Metabolic pathways
cdw01110  Biosynthesis of secondary metabolites
cdw01250  Biosynthesis of nucleotide sugars
Module
cdw_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:cdw00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    CDPW8_0364 (rmlD)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    CDPW8_0364 (rmlD)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    CDPW8_0364 (rmlD)
Enzymes [BR:cdw01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.133  dTDP-4-dehydrorhamnose reductase
     CDPW8_0364 (rmlD)
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.3  Acting on carbohydrates and derivatives
    5.1.3.13  dTDP-4-dehydrorhamnose 3,5-epimerase
     CDPW8_0364 (rmlD)
SSDB
Motif
Pfam: RmlD_sub_bind dTDP_sugar_isom Epimerase GDP_Man_Dehyd Polysacc_synt_2 NAD_binding_4
Other DBs
NCBI-ProteinID: AEX69026
LinkDB
Position
complement(359671..361017)
AA seq 448 aa
MQVRPTAIAGVVIVDLDVHGDNRGWFKENWQREKMVAAGLPDFQPVQNNISFNAERGVTR
GLHAEPWDKFVSVAHGEVFGAWCDLREGSDTFGEVVTCTITPHTAVFVPRGVANGFQALV
DNTSYTYLVNDHWSPDATYTAVNLDMIDWPLPPTEISDKDRCHPQLADATPMPPRRILIT
GAHGQLGRALAELLPDAELCSHADFDVVNPPQRPWRQYEAIINCAAYNNVDAAEDDRARA
WEVNAVAPARLAQIATENNLTLVHVSTDFIFDGTTLVHEETEAPSPLSVYGASKAAGDIA
AAVTPKHYVVRTSWVFGQGGNFVETMRLLAQRGIRPNVISDQRGRPTHAADLAAGIVHLL
RSGADYGVYNLSNSGDVVGRDDLARAVFEHCGVSGAAVTSVTTAEYEALTGPLAKRPAES
TFNLDKIVATGFQPRPWRDAVRDYLGTK
NT seq 1347 nt   +upstreamnt  +downstreamnt
atgcaggttcgccccactgccattgccggtgttgttattgtcgacctcgacgttcatggc
gataaccgtggatggttcaaggagaactggcagcgggaaaagatggtggcggcgggcttg
ccggatttccagccggtgcaaaacaacatttcttttaacgctgagcggggcgtgacacgt
ggtttgcacgccgaaccgtgggacaagttcgtatcggtggctcatggcgaagtgtttggt
gcgtggtgcgacctgcgcgagggttctgacaccttcggcgaggtagttacctgcaccatt
acccctcatactgcggtgtttgtgccgcgtggggtggccaatggttttcaggcactggta
gacaacacaagttacacctacttggtcaacgaccattggtcgccggacgctacttatact
gcggtgaatctggacatgatcgattggccgcttcctcccacggagatttcggataaggat
cgttgccacccccagcttgccgacgccaccccgatgccaccgcgtcgcattctcatcacc
ggcgcccatggccagttggggcgtgcgctagccgagttgttgccagatgccgagttgtgt
tcgcatgctgatttcgatgtggttaacccaccgcagcgcccgtggcgccagtatgaggcg
attattaactgtgcggcctacaacaatgtggatgcggcagaagatgatcgtgcccgcgct
tgggaggtcaatgctgttgccccagcaaggctggcccagattgctacggagaataatctg
acgttggtgcatgtgtcgacggatttcattttcgacggcaccacgttagtgcatgaggag
acggaagcgccgtcgccgttgtcggtgtacggggcgtcgaaggctgcgggtgatattgcg
gctgctgtgacaccgaaacactatgtggtgcgcacctcgtgggtctttggccaaggtggc
aactttgtggaaactatgcgcttgctggcgcagcgcgggattcgccccaatgtgattagt
gaccagcgtggtcgtccaacccatgcggctgatctggcggcgggtattgttcatttgctg
cgcagcggagcagattatggtgtgtacaacctttctaattctggcgatgtggtcggccgc
gatgatcttgcccgcgcagtatttgagcattgtggggtatccggtgcggcggtaacctct
gttactacagccgagtacgaggccctaacaggcccgttggccaagcgccccgcggagtcg
acgttcaacttggacaaaattgtggcgacgggttttcaaccgcgcccatggcgggatgct
gtgcgggattacttgggcaccaagtag

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