Corynebacterium diphtheriae PW8: CDPW8_1778
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Entry
CDPW8_1778 CDS
T01701
Symbol
folC
Name
(GenBank) dihydrofolate synthase / folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
cdw
Corynebacterium diphtheriae PW8
Pathway
cdw00790
Folate biosynthesis
cdw01100
Metabolic pathways
cdw01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
cdw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CDPW8_1778 (folC)
Enzymes [BR:
cdw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CDPW8_1778 (folC)
6.3.2.17 tetrahydrofolate synthase
CDPW8_1778 (folC)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AEX70428
LinkDB
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Position
complement(1871300..1872796)
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AA seq
498 aa
AA seq
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MKDEDLHLGEVSLIETGLSLPIDVNADTEAPAPREITADDLMDLATVEAELDQRWSEVKI
DPTLERVEMLMDLLGHPEHAFPAIHVAGTNGKTSTVRMIESLMRAFHRRTGRTTSPHLQL
VTERIAIDGQPIHPRDYVRTWNEIKPYVEMVDAHSEANGGPKMSKFEVLTAMAYAAFADA
PVDVAVVEVGMGGRWDATNVINSDVAVVMPVGLDHTDFLGDTIEKIAAEKAGIIKSRWDA
SDLLTPPDNVAIVAEQDPAAMNVILEQAVSVDASVARAGVEFGVMDAAIAVGGQQISIRG
LGGEYPDIFLPLSGEHQARNAATALAAVEAFFGAGAGRQLDLDTVREGFATVQSPGRLER
VRTAPTVFIDAAHNPHGAAALGKALERDFDFSRLIGVVAVLGDKDYVGVLRALEPHLSEI
VVTTNSSPRALAADDLAEEARNIFGEERVHVAYSLPSAVELAVELAEDTEVQSGSGVIVT
GSVVTAGEARTLFGKDPV
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
gtgaaagacgaggatctccacctaggagaagtctctctcattgagacgggcctttcgttg
cctatcgacgtcaacgcggacaccgaagcacccgccccgcgcgagatcacggccgatgac
ctcatggatttggccaccgtcgaagcggagctggatcagcgctggtccgaggtcaaaatt
gaccccacgctcgagcgtgtagagatgttgatggatctgctgggtcatccagaacatgcg
tttccggctattcacgtagccggaaccaacggcaaaacatcgacggtacgcatgatcgaa
tccctcatgcgtgctttccaccgtcgcacgggacgcaccaccagcccgcaccttcagctg
gtcaccgaacgcattgctatcgacggccagccgatccacccacgtgactatgtacgcacg
tggaacgagatcaaaccctatgtggagatggtcgacgctcattctgaggccaacggtggc
cccaagatgagcaagttcgaagtgctcacggccatggcctacgctgcgtttgcagacgca
ccagtggacgttgcagtggtggaagtgggcatgggtggtcgctgggatgccaccaatgtg
atcaattctgatgttgctgtggttatgcccgtggggctggaccacactgattttcttgga
gataccatcgagaaaatcgctgctgaaaaagctggcatcatcaagtcccgttgggatgcc
tccgacctgctgaccccgccggataacgtcgctatcgttgcggagcaagatcccgcggcg
atgaacgtgatccttgaacaggccgtgagcgtggatgcttctgtggcgcgcgccggtgtg
gaatttggggtgatggatgctgctatcgcggttggtggtcaacagatcagtattcgtggc
ctaggtggcgagtaccctgacatcttcttgccactttctggcgagcaccaagcccgcaac
gcagcgaccgccttggctgctgtggaggctttcttcggtgcgggtgctggccgccagcta
gaccttgatacggttcgcgaaggttttgctaccgtgcagtccccaggtcgtctcgagcgg
gtgcgcactgctcccacggtatttatcgacgctgcccacaaccctcacggtgctgccgca
ttgggcaaagccttggagcgtgacttcgatttctcgcgcctcattggcgtggtagcagtg
cttggcgacaaagactacgtgggcgtgttgcgtgccctggaacctcatctatccgagatc
gtggtgaccacgaactcttcgccgcgcgctcttgctgccgatgaccttgccgaggaagca
cgcaacatctttggcgaagaacgcgtgcacgtggcgtactcgctgccgtcggcagtcgaa
ctggcagtggaacttgccgaggataccgaggtgcaatccggttccggtgtaatcgtcaca
ggctctgtggtcactgcgggtgaggcccgtaccctgtttggaaaggaccccgtatga
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