Corynebacterium efficiens: CE2057
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Entry
CE2057 CDS
T00103
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cef
Corynebacterium efficiens
Pathway
cef00300
Lysine biosynthesis
cef00550
Peptidoglycan biosynthesis
cef01100
Metabolic pathways
cef01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cef00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CE2057 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CE2057 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CE2057 (murF)
Enzymes [BR:
cef01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CE2057 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF4597
DUF6278
Motif
Other DBs
NCBI-ProteinID:
BAC18867
UniProt:
Q8FNT6
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Position
complement(2177921..2179507)
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AA seq
528 aa
AA seq
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MTVSRFVRHCDTRSPTGKESKSTPMIELTLGQIVEIVGGELAGGAQPDTTVTGTVEFDSR
QVTAGGLFLALPGARVDGHEYATTAIGQGAVAVLAARPVDVPSIIVPPVTPTDSNADIYA
HDPEGHGAAVIEALSKLARHVVDLAVGAHDLTVVALTGSAGKTSTKDFIATVLSMAGDTV
APPGSFNNEVGLPHTALRCTTHTRYLVAEMSARGIGHIAHLARITPPRIGAVLNVGSAHL
GEFGSRANIAQAKGELVEALPAAADGGVAVLNADDPFVAAMAPRTTARVVTFSTANPPAP
GAQYWAGDLELDDVARASFTLHTPRGSWPVSLQVFGEHQVANALAAAAVAIEAGVDETTV
VSGLSSHAAASAHRMDVRTRPDGVTVINDSYNANPDSMRAGVAALAYTASARRDATSWAV
LGQMGELGDEAVQEHRALGAELAKYHVERLIAVGDNPNCRALREQAAALGVRTDAVPDAA
SAVDLLRHQVRDGDVVLVKASNADQLWRVAEELHAMFDGDSRRDVEGL
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
atgaccgtgagcaggttcgtgaggcactgcgacacacgcagtccgacggggaaggaaagt
aagtccacacccatgattgaactgacacttggacaaatcgtcgagatcgtcggcggtgaa
ctcgccggcggcgcgcagccggacaccacggtgaccggcaccgtcgaattcgattcccgc
caggtcaccgccggcgggttgttcctcgccctgcccggcgcgcgcgtggacggccatgaa
tatgcgaccaccgccatcggccagggtgccgtcgcggtgctcgccgcccggcccgtcgac
gtgccctccatcatcgtgcccccggtgacccccactgactccaatgccgacatctatgcc
catgaccccgaggggcacggtgccgcggtcatcgaggcactgtcgaaactggcccgccac
gtggtggacctcgctgtgggtgcccatgacctcaccgtggtcgcgctgaccggttccgct
ggtaagacctccaccaaggatttcatcgccacggtgttgtccatggccggtgacaccgtc
gcaccccccggctccttcaacaacgaggtgggcctgccccacaccgcactgcgctgcacc
acccacacccggtacctcgtggcggagatgtccgcgcgcggcatcggacatatcgcccat
ctggcgcggatcaccccaccgcgcatcggtgcggtgctcaacgttggatccgcccacctt
ggtgaattcggctcccgggccaacatcgcccaggccaagggggagctcgtcgaggcgctg
cccgctgccgccgacggcggggtcgccgtcctcaacgccgatgatcccttcgtcgccgcg
atggcaccgcgcaccaccgcacgcgtcgtgaccttctccaccgccaacccgccggccccc
ggagcacagtactgggccggtgacctggagctcgatgatgtggcccgggccagcttcacc
ctgcacaccccccgtggctcctggccggtgagcctccaggtcttcggtgaacaccaggtg
gccaacgccctggccgccgcagccgtggccattgaggccggggtcgatgagaccaccgtg
gtgtcaggactgtcttcgcatgcggcggcctcagcccaccgcatggatgtgcgcacccgc
ccggatggtgtcaccgtcatcaacgactcctacaatgcgaacccggactccatgcgtgcc
ggtgtcgctgcactggcctacaccgccagcgcccgtcgggatgcgaccagctgggctgtc
ctaggccagatgggtgagctcggggatgaagcggtgcaggagcaccgtgcactgggcgct
gagctggccaagtatcatgttgaaaggctcatcgcggtaggggacaaccccaactgccgt
gccctgcgggagcaggccgccgccctgggagtgagaaccgatgccgtccccgatgccgct
tcagcagtcgacctgctgcggcaccaggtgcgcgacggtgatgtggtgctggtcaaggcc
tccaatgccgaccagctctggcgtgtggccgaggagttgcacgcgatgtttgacggcgat
tcgcgccgtgatgtggaaggactctaa
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