Caenorhabditis elegans (nematode): CELE_B0348.4
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Entry
CELE_B0348.4 CDS
T00019
Symbol
egl-8
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8
KO
K05858
phosphatidylinositol phospholipase C, beta [EC:
3.1.4.11
]
Organism
cel
Caenorhabditis elegans (nematode)
Pathway
cel00562
Inositol phosphate metabolism
cel01100
Metabolic pathways
cel04070
Phosphatidylinositol signaling system
cel04081
Hormone signaling
cel04082
Neuroactive ligand signaling
cel04310
Wnt signaling pathway
cel04361
Axon regeneration
Module
cel_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
cel00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
CELE_B0348.4 (egl-8)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
CELE_B0348.4 (egl-8)
04070 Phosphatidylinositol signaling system
CELE_B0348.4 (egl-8)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
CELE_B0348.4 (egl-8)
04081 Hormone signaling
CELE_B0348.4 (egl-8)
09150 Organismal Systems
09158 Development and regeneration
04361 Axon regeneration
CELE_B0348.4 (egl-8)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cel04131
]
CELE_B0348.4 (egl-8)
Enzymes [BR:
cel01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
CELE_B0348.4 (egl-8)
Membrane trafficking [BR:
cel04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
CELE_B0348.4 (egl-8)
Endocytosis
Macropinocytosis
Phospholipase C
CELE_B0348.4 (egl-8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
PH_14
PLCB1-4-like_EFh
PLC-beta_C
EF-hand_like
C2
Motif
Other DBs
NCBI-GeneID:
178537
NCBI-ProteinID:
NP_001021347
WormBase:
WBGene00001177
Ensembl:
WBGene00001177
UniProt:
G5EBH0
LinkDB
All DBs
Position
V:<20818..>43704
Genome browser
AA seq
1431 aa
AA seq
DB search
MAKEFQFNWKPTIIPELLHGSVFDRYDDESTCLELNAQVRIDENGFFLRWLIEGKDAVVL
DMGQIWEARTGGLPKDGRIMFELEQRGASETIAERTIWITHGQDLVNVQSFFLVAESVEL
AKTCRAGINDILKSSRIRHVCPTTQLMKYHTWLTMNVNERRKIPIKLIIKTFSSGKPEKM
VQKCLNDLGLGGDKYTPARVINRSMGKKFRNFYKCSRGRKRKEREELDVDILTFEKFQRL
YNKICPRTEVQELFVKLSGQKEYLTKERLINFLNEEQRDPRLNEILFPFFDSQRIVALLK
KHENDIKYQEDGKMSGDGFLRFLMSDENPPVFLDRIEMFMDMDQPLCHYYINSSHNTYLT
GRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFKDVLVQI
RDTAFARSDFPVVLSFENHCSKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPN
RLRKKILIKNKRLKTDIERHQLDQFLREGKLDEEDELNETPEVVGEDSVSPRSGGSGGTG
APEEVDDDTSDDDDDPSVQTSLNVMRTIPTVNTTSNNGSNRSARSSLDTPSPSGGSLMVP
DRATSTATSIKNAVLARSPNFSSLRQKLSFKRRQSPLAGDQRAHPEVEQPVSSSSPATPS
ISGPPPCATSSGSTSSITITTTGCSTSSSGPSKHILGGEMPAKENDEAHPELKQNFIAKN
LKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANN
LHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMV
SLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSESPVDGVIAAHCSVRV
ISGQFLSDRKIGTYVEVEMYGLPTDTIRKEHKTKVIPGNGLNPVYNEDPFVFRKVVLPEL
AVLRFAVYDENGKQLGQRILPLDGLQAGYRHISLRSDTNQSFILSPVLFVQIVIKTYVPD
ELSGLVDALADPRAFLSEQKKRQEALAHMGVDDSDIPDVPNTRNMALRHVKQPPRQNGSS
ADLLANNGQTGSARGDQTSSMASSTIRSPNEQPQPVAVDKFKVDPIEVDDLRRDKAFAKL
LKRFQKELDDLRKKHQKQRDSIQKQQPARRRNSSIAWIQTNVDKLITNNRRSTKKEKGSR
RSLTASVSSGCGSASGTVTVSVCSPSGASCSGYSTGGPSTPVACNSDGTGSPATIGSPVP
QDLVNNDRVRSLVNTQTGEWSAMVRRHDEEEFELKKVQLKEQFDLLRKLMSEAQKNQMLA
LKLRLEAEGKDLKQTQTKKSMEDAKVIQLDKGIKTKAERDRRVKELNEKNLKMFVEERKR
LAMKAQKHEEQLTKRHLDQLEQLDKDFHKALDAEVGNYKEEQLAAQPTSVV
NT seq
4296 nt
NT seq
+upstream
nt +downstream
nt
atggcaaaggagttccagttcaattggaagcccactattatccctgaacttcttcatgga
tcggttttcgatcgatatgatgatgaaagtacgtgtctggaactaaatgctcaagttcga
attgacgagaacggtttctttctccggtggctgatcgaaggaaaagatgctgtcgtactc
gatatgggccaaatatgggaagctcgcacgggcggcctacccaaagacggccgaattatg
ttcgaattggagcagcgcggagccagcgaaacgatagctgaacgcacgatatggatcacg
catggccaggatttagtcaatgttcagtcgttttttcttgtcgccgaaagtgtcgagttg
gcaaaaacgtgtagagcgggcattaatgatattctaaagtcgtccagaatacgacacgtg
tgtccaactacccaattgatgaaataccatacatggctcaccatgaatgtcaacgaacga
cgaaaaatcccgatcaagttgataatcaaaacattttcgtctggaaaacctgaaaaaatg
gttcaaaagtgtctaaatgacttgggtcttggaggcgataagtacacgccggcacgggtc
atcaatcgatcgatgggcaagaagtttcggaatttctacaagtgcagtcggggacgaaaa
cgaaaggagcgcgaagaacttgacgtcgacatcctcacctttgaaaaattccagaggctc
tataacaagatttgtccgagaaccgaagttcaagagctgtttgttaaattatccggacag
aaagagtacctaaccaaagagcgactcatcaattttctgaatgaagaacaacgtgatcca
cgactcaacgagatcctcttcccattttttgattctcagcgtatcgttgcgcttctcaaa
aaacacgaaaacgacataaaatatcaagaagatggaaaaatgtccggtgacgggtttctc
cgattcctgatgtcagacgagaacccgccagtgtttctagaccgaattgaaatgtttatg
gatatggatcaaccgctgtgtcactactacatcaatagttcccataacacgtatcttacc
ggacggcagtatggtggaaaatcgtcttctgagatttatcgacaagttttgctcagcgga
tgtaggtgtattgagcttgattgttgggatggtactggtgaaaataaaggagaacccatt
atcactcacggaaaggccatgtgcacagacgtgttcttcaaggacgtcctggtacaaatt
cgagacaccgcatttgcccggtcggattttccagtggtcctttccttcgaaaaccattgc
tcaaaatcaaatcagctgaaaatggccaaatattgtatggacatttttggagatatgctg
ctgtccaaaccgtttgaagatgcgcctcttgaccccggagtctccctaccttctccaaac
cgcctgcgaaagaagatccttatcaaaaataagcgattaaaaaccgacatcgaacgtcac
caacttgaccaatttctgcgggaaggcaaactggacgaggaggacgagctgaatgagacg
cccgaagttgtcggagaggactccgtatcacctcgaagcggcgggagcggtggcaccgga
gccccggaagaagtggatgatgacacgtccgacgacgacgatgacccgtcggttcagaca
tcgctgaacgtgatgcgcaccatcccgaccgtgaacaccacatcgaacaacggatcgaat
cgatcggcaagaagttcactggacaccccatccccatccggtgggagcctgatggttcca
gatagggcaacatcgacagcgacgtcgatcaagaacgccgtgctcgcgaggtctccgaac
ttctcctcgttgagacaaaagttgtcgttcaagcggagacaatcaccactagcaggcgat
cagcgtgctcatccggaagtcgagcaacccgtgagctcatcctctccagccacaccgtcc
atcagcggacccccgccgtgtgccacgtcatcaggttcaacgtcatcaatcactattacc
acaacgggatgctccacgtcatcgtcgggaccctcaaaacatattctagggggtgaaatg
cccgccaaggaaaacgacgaagcacatccggagctaaagcagaatttcattgctaaaaat
ttgaaaggattcgggttttcgaaaaaacaaccggtactgacaaaagaagaagaggagcgg
attttcgccgagtatcattataccggggcaactacgaatatacatccgttactctcttca
ctggtcaattatacacatcctgtcaagttttctggatttgacgttgcggaagccaacaac
ctgcacttccacatgtcctcattttctgagtcaaccggtctcggctacctaaaacaatcg
gcgccggaatttgtgaactacaacaaacgacaatcgagtagaatttatccgaaaggagcc
agagttgattcttccaattttttgccgcaaattttctggaacgccggatgtcaaatggtg
tcgctcaactttcaaactcccgatgtctacatgcaattgaacatgggaaaattcgagtac
aacggtggctcggggtatctgctaaaaccagatttcctccgaagacccgacagaacattc
gacccattttccgagagcccggtggacggagtgattgcagcacattgtagtgttcgtgtc
atctcgggtcaattcctatcggatcgcaaaatcgggacatacgttgaggtggaaatgtac
ggactacctactgacactattcgtaaggagcacaagacgaaggtaatacccgggaacgga
ctgaatccagtttacaacgaggatccgtttgtcttccgaaaagttgtgctccccgagctc
gccgtgctccggttcgccgtctacgatgagaacggcaagcagctgggtcagcggattctt
ccgctggatgggcttcaggcaggatatcggcatatttcgctgaggtctgacacgaatcag
agcttcattctgtcacctgtgctctttgtgcaaattgtgatcaagacttatgtgccggat
gagctcagtggcctcgtcgatgctctcgccgacccacgagcattcctctcggagcagaaa
aaaaggcaggaagccctggctcacatgggtgttgacgatagtgatattcctgatgtgccc
aacaccaggaatatggctctccgacacgtgaaacaacctccaaggcagaacggatcgtca
gctgatctgctggcaaacaacggccaaactgggtcggctaggggtgatcagaccagctcg
atggcttcaagtactattcggtcacccaacgaacaaccgcagccagtggctgtggataaa
tttaaggttgacccaatcgaagttgacgatttacgacgagacaaagcttttgcaaaattg
ctcaagagatttcaaaaagagttggatgatctcaggaagaaacatcagaagcagagggat
agcattcaaaaacagcagccggctcgccgccgtaattcgtccatagcgtggatccaaacc
aacgtcgacaagctcatcacaaataaccgacgttccacgaaaaaagaaaaaggctcaagg
agatccctgacggcttcagtatcatctggatgtggaagtgcatctggaactgtgactgtc
agtgtttgcagtccttctggcgcgagttgcagtgggtactccactgggggtccttcgaca
ccggtggcatgtaactctgatggtaccgggtctccagcgactattggaagtccagtgcca
caagatttggtcaataatgatagggtccgatctctcgtgaacactcaaaccggagaatgg
tccgctatggtccgtagacatgacgaggaagagtttgagctgaaaaaagtacagctcaaa
gagcaattcgatctgctaagaaaactcatgagtgaagctcaaaagaaccaaatgttggct
ctgaagctccggttagaagccgaagggaaagatctaaagcagacgcagacgaaaaaaagc
atggaagatgcgaaagttattcaattggacaaaggtattaagaccaaggcagaacgtgat
cgtcgtgtcaaggaactcaacgagaagaacctgaaaatgtttgtggaggagaggaagaga
ttagccatgaaagcccaaaagcacgaagagcaactcacaaaacgacatctcgaccagctc
gagcaactagacaaggatttccataaggccttggatgcggaggtcggcaactacaaagaa
gagcaactggctgctcaaccgacttctgtcgtttga
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