Caenorhabditis elegans (nematode): CELE_F37B12.2 Help Entry CELE_F37B12.2     CDS       T00019                                  Symbol gcs-1 Name (RefSeq) Glutamate--cysteine ligase   KO K11204   glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2] Organism cel  Caenorhabditis elegans (nematode) Pathway cel00270   Cysteine and methionine metabolism cel00480   Glutathione metabolism cel01100   Metabolic pathways cel01240   Biosynthesis of cofactors cel04212   Longevity regulating pathway - worm Module cel_M00118   Glutathione biosynthesis, glutamate => glutathione Brite KEGG Orthology (KO) [BR:cel00001]  09100 Metabolism   09105 Amino acid metabolism    00270 Cysteine and methionine metabolism     CELE_F37B12.2 (gcs-1)   09106 Metabolism of other amino acids    00480 Glutathione metabolism     CELE_F37B12.2 (gcs-1)  09150 Organismal Systems   09149 Aging    04212 Longevity regulating pathway - worm     CELE_F37B12.2 (gcs-1) Enzymes [BR:cel01000]  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.2  Acid-D-amino-acid ligases (peptide synthases)     6.3.2.2  glutamate---cysteine ligase      CELE_F37B12.2 (gcs-1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  GCS GCS2 Motif Other DBs NCBI-GeneID:  174438 NCBI-ProteinID:  NP_495927 WormBase:  WBGene00001527 Ensembl:  WBGene00001527 UniProt:  Q20117 LinkDB All DBs Position II:complement(9035562..9038301) Genome browser AA seq 654 aa AA seqDB search MGLLTKGSPLTWAETVPHIDYIKKHGIAQFINLYHRLKSRHGDQLKWGDEIEYTIVKFDD ANKKVRVSCKAEELLNKLQAEEQVNAMLGTANRFLWRPEFGSYMIEGTPGMPYGGLIACF NIVEANMKLRRQVVKKLLKKDETCLSISFPSLGVPGFTFPEVAADRKNDDAANSVFWPEQ AVFLGHPRFKNLTKNIKGRRGSKVAINVPIFKDTNTPSPFVEDLSALGGPDDTRDAKPDH IYMDHMGFGMGCCCLQVTFQAVNVDEARWLYDQLTPITPILLALSAATPIFRGKLSNVDS RWDIISASVDDRTPEERGLEPLKNSKWVIDKSRYDSTDCYIYPCSVGYNDIPLQYDETIY KQLIDGNIDEPLAKHIAHMFIRDPHQVFRERIEQDDEKSSEHFETIQSSNWMNMRFKPPP PDAPEIGWRVEFRPTEVQLTDFENAAYCCFVVLLTRMMISFRLTYLMPISMVTENMKRAQ QKDAVLNQKFLFRKGLAECKSAPENLKGSEKCGPPSQDIEEMSIDEIINGKKNGFPGLIS LIRQFLDSADVDVDTRCTISQYLNFISKRATGEINTLAHWTRGFVQSHPAYKHDSDVNDN IVYDLLKKMDAISNGEDHCEKLLGCYRSKTDHAISAAVRKAEEHMIVSSQKRAH NT seq 1965 nt NT seq  +upstreamnt  +downstreamnt atgggtcttttgacgaaaggtagtccgttgacgtgggcagaaaccgtaccgcacattgat tatatcaagaagcacggaattgctcaattcatcaatctctaccatcgtctgaaatcaaga cacggagatcaattgaaatggggagatgagattgaatacactattgtaaaatttgatgac gcaaacaagaaagttcgcgtgtcgtgcaaagctgaagagcttcttaataagttacaagcc gaagagcaggtgaatgcgatgcttggaactgccaatcgattcctttggagaccagaattc ggatcctacatgatcgagggaacccccggaatgccttacggaggtctcatcgcttgcttc aacattgtcgaggcaaacatgaaattgcgcagacaggtcgtcaaaaagttattaaagaag gatgaaacatgtctatcgatatcgttcccatctcttggagtacctggattcacattcccg gaagtagcagctgatagaaagaatgatgatgcagctaatagcgttttctggccagaacaa gctgtattcttgggccatccacgtttcaagaatcttaccaaaaatattaaaggtcgcaga ggaagtaaagtagctatcaacgtcccgatattcaaggatacgaacacccccagtccattc gttgaagatttatctgcacttggaggtcctgatgatactcgtgatgcgaaacctgatcac atttatatggatcatatgggattcggaatggggtgctgttgtcttcaagtcactttccag gctgtgaacgtcgatgaagccagatggttgtacgatcagctgacaccgattacaccgatt ctactggcactctctgccgccacaccaatcttccgtggaaaattatccaatgtcgattct agatgggatatcattagtgcaagtgtcgacgatcgtacaccggaggaaagaggattggaa cctctcaagaattcgaaatgggttattgataagagtcgctacgactccacggactgttac atttatccatgttctgttggctacaatgatattcctcttcaatacgacgaaaccatatat aaacaactaattgatggaaatattgatgagccactggcaaaacatattgcgcatatgttc attcgtgatccacatcaagttttccgtgagcgtatcgaacaggacgatgagaaaagcagt gaacactttgaaacaattcaatcatcgaattggatgaacatgcgattcaagccaccacca ccagatgctccagaaatcggatggagagtcgaattccggccaactgaagttcaactgacc gactttgaaaatgcagcatactgttgcttcgttgtattgctcaccagaatgatgatctcc ttcaggctgacatatttgatgccaatttcaatggttactgaaaatatgaagcgtgctcag caaaaagatgcagttctcaatcagaaattcctgttcagaaaaggattggctgagtgcaaa tctgctcccgaaaatttgaaaggatcggagaaatgtggaccacctagtcaagatattgaa gaaatgtcgattgatgagattatcaatggaaagaaaaatggattcccaggtctcatttca cttattcgccaatttctagattctgctgatgttgatgtggatactcggtgtacgatttct caatatttgaactttatttcgaaacgagcaactggagagattaatactttggctcactgg acacgtggattcgtacaatctcatcctgcatacaaacatgacagtgatgtaaatgataat atagtttacgatcttttgaaaaagatggatgccatctcaaacggagaagatcactgtgag aagctgctcggatgctaccgctctaaaaccgatcatgccatttctgctgctgttcgcaaa gctgaagagcacatgatcgtgtccagccaaaaacgtgcacattag

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