KEGG   Chanodichthys erythropterus (predatory carp): 137008226
Entry
137008226         CDS       T10334                                 
Symbol
ryr2a
Name
(RefSeq) ryanodine receptor 2
  KO
K04962  ryanodine receptor 2
Organism
cery  Chanodichthys erythropterus (predatory carp)
Pathway
cery04020  Calcium signaling pathway
cery04260  Cardiac muscle contraction
cery04261  Adrenergic signaling in cardiomyocytes
cery04371  Apelin signaling pathway
Brite
KEGG Orthology (KO) [BR:cery00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    137008226 (ryr2a)
   04020 Calcium signaling pathway
    137008226 (ryr2a)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    137008226 (ryr2a)
   04261 Adrenergic signaling in cardiomyocytes
    137008226 (ryr2a)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:cery04040]
    137008226 (ryr2a)
   04990 Domain-containing proteins not elsewhere classified [BR:cery04990]
    137008226 (ryr2a)
Ion channels [BR:cery04040]
 Voltage-gated cation channels
  Ryanodine receptor
   137008226 (ryr2a)
Domain-containing proteins not elsewhere classified [BR:cery04990]
 EF-hand domain-containing proteins
  Other EF-hand domain-containing proteins
   137008226 (ryr2a)
SSDB
Motif
Pfam: RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY MIR Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 RBSN_mid
Other DBs
NCBI-GeneID: 137008226
NCBI-ProteinID: XP_067226244
LinkDB
Position
19
AA seq 4857 aa
MTDGEAEDEIQFLRTDDEVVLQCSATVQKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPD
LSICTFVLEQSLSVRALQEMLANTEERAEGTAQGGGHRTLLYGHAVLLRHSYSGMYLCCL
STARSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLH
LSYGNGSLHVDAAFQQTLWSVAPICSGSEVAQGFLIGGDVLRLLHGHMDECLTVPSGEHG
EEQRRTVHYEGGAVSIHARSLWRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSMMDDQG
LLLMDKEKADVKSTAFCFRSSKEKLDFGLRKEVDGMGAPDIKYGDSVCYIQHVDAGLWLT
YQSVDAKCARMGGVQRKAIMHHEGHMDDGLTLSRSQNEESRTARVIRSTVFLFNRFISKK
GKTSTLDLPIESVSLSLQDLIGYFQPPDEHLEHEDKQNRLRALKSRQILFQEEGMINLVL
ECIDRLHVYSSAAHFADVAGKEAGQSWKSILNSLYELLAALIRGNRKNCAQFSSSLDWLI
SRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDVLCSLCV
CHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGVSEGSAQYRKWYYELIV
DHVEPFMTAEATHLRVGWASTQGYWPYPGGGEGWGGNGVGDDLYSYGFDGLHLWAGCVAR
SVSSPNQHLLRAEDVVSCCLDLSAPSISFRINGQPVQGMFENFNSDGLFFPVVSFSAGVK
VRFLLGGRHGEFKFLPPSGYAPCFEAVLPREKLRVEHSQEYKHDHGKTRDLLGPTVTLSQ
AAFTPTPVDTSQIVLPPHLERIREKLAENIHELWVMNKIDLGWTYGTVRDDNKRQHPCLV
EFSRLPEQERSYNLQMSQETLKTLLALGCHVGVADERAAEKVKNLKLSAKYELSSGYKPA
PMDLSHIKLASTQEAMVDKLAENAHNVWARDRIRQGWTYGVQQDIKNRRNPRLVPYVLLD
ERTKKSNKDSLREAVRTLLGYGYNLEAPDQDHADAGNLSAERFRIFRAEKTYSVSGGKWY
FELEVVTAGEMRVGWARPGCLPDLELGSDEQAFVFDGFKAQRWHQGNEHFGRSWQSGDVV
GCMVDMNERTMMFTLNGEVLLDDSGSELAFKDFEVWDGFIPVCSLGICQVGRMNFGKDVS
TLKYFTICGLQEGYEPFAVNMNRDLTMWISKRLPQFIPAPLNHEHIEVTRIDGTVESPPC
LKVTQRSFGSQNSNTDIMFYRLSMPIECSEAFLRSPGGTLAANGSFFSPKRDLEELLSLS
VCQYYYSVRIFPGQEPASVWVGWVTSDFHQYDPAFELSKVRTVTVTLGDEKGKVHESIKR
SNCYMVWGGECSSPSQGRNNNGLEIGCLVDTANGLLSFTSNGKELSTYYQVEPSTKLFPA
VFAQATSPNVFQFELGRIKSVMPLSAGLFKSERKNAVPQCPPRLHVQFLTPVLWSRVPNQ
FLRSEVTRVNERLGWMVQSSEPLQFMTLHIPEENRSLDILELTEQRDLLKFHFHTLRLYS
AICALGNNRVAHALCSHVDEAQLLYAIQNKYMPGLLRTGYYDLLIDIHLSSYATARLMMN
SEYIVPMTAETKSITLFPNEKKKHGLPGIGLSTSLQPRMRFSSPSFVGHHGTVAGSDCFQ
YSPEFPLETLKSRTMEMLTEAVREGSLHVRDPVGGSTEFLFVPLIKLFYTLLIMGIFHNG
DLKTILQLIEPSVFSQDGGGGATEAEDGSGRGRLEGGGAEEHGLRGKMPKEGLLQMKLPE
PVKLQMCHLLQYLCDCQVRHRIEAVVAFSDDFVANLQDNQRFRYNEVMQALNMSAALTAR
KTKEFRSPPQEQINMLLNFKDEKQDCPCPEDIREQLLDFHEDLMTHCGIEMDDDKSGDGD
DFTIRGRLMSLVEKVTYLKKKMTDLPKKKKSKKPSTLQQLISETMVRWAQESVIEDPELV
RAMFVLLHRQYDGIGGQVRALPKTYTINAVSVEDTINLLASLGQIRSLLSVRMGREEEKL
MIHGLSDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEITFPKMVANCCRFLC
YFCRISRQNQKAMFDHLSYLLENSSVGLASPSMRGSTPLDVAAASVMDNNELALALREPD
LEKVVQYLAGCGLQSCVMLMSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVV
RLLIRRPECFGPALRGEGGNGLLAAMEEAIKISEDPSRDGPSPTTEESRTLSDVMEEEED
DTIHMGNAIMTFYAALIDLLGRCAPEMHLIHAGKGEAIRIRAILRSLIPIEDLVGVISIP
FLMPTLAKDGSVIEPDMSAGFCPDHKAAMVLFLDRVYGIEDQNFLLHLLEVGFLPDLRAA
ASLDTAALSATDMALALNRYLCTAVLPLLTKCAPLFAGTEPFASLIDSLLHTVYRLSKGC
CLTKAQRDAIEECLLAVCGKLRPSMMQHLLRRLVFDVPVLNEHTKMPLKLLTNHYERCWK
YYCLSGGWGSFGAASDEELHLSRKLFWGIFDALARKKYDVELFKLALPCLSAVAGALPPD
YMESNYVAMMEKQSSMDAEGNFNPQPADTSSVVVPEKLDHFINKYAEYSHEKWSMEKFAV
GWIHGEQMCESSKVHPLLKPYKCLSEKDKEVYRWPIRESLKTMLSWGWSIERTKDSDAST
LHSRTRRISLSSQGAHGFSPRPVDMSNVTLSRDLHSMAELLAENYHNIWAQKKKLELEAK
GGGSHPLLVPYDTLTAKEKSKDREKAQDILKFFQINGYSVSRAMKEQDLDTPSIEKRFAY
TFLQQLITYVDEAHGHMLEFDAGIRLKGEKIPHEQQVKFFGKVVLPLVDQYFKNHRLYFL
STAVRPISSGGHASNKEKEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDAR
TVMKTGQDSVKAALRAFFDNASEDLEKTMENLRQGQFTHTRMQPKGVTQIINYTTVALLP
VLSSLFEHIGQNLFGEDLILDDVQVSCYRILNSLYSLGTSKSIYVERQRPALGECLAAFS
GAFPVAFLEPNLNKHNTYSIYNCKGSRERAALGLPAQVEEVCALVPSLERALQEIMELAE
SGMRYTQMPHVMEVLLPMLCSYMSHWWEHGPESDPERGESCCTSLTSEHMNTLLGNILKI
IYNNLGIDEGAWMKRLAVFSQPIIGKAKSQLLKTHFLPLMEKLKKKAATVLQDEEHMKAE
GRGEMSESELLILDEFTILVRDLYAFYPLLIRFVDYNRAKWLKEPNTEAEELFRMVAEVF
IFWAKSHNFKREEQNFVVQNEINNMSFLITDTKSKMSKGGVSDQERKKMKKRGDRYSLQT
SLIVAALKRLLPVGLNICAPGDQELIGLAKSRFTQKDTEDEVREIIRNNLHLQGKLEDPA
IRWQMALYKDMPNRSEDSSDPEKTVDRVLNIAHVLFHLDQVEHPQRSKKAVWHKLLSKQR
KRAVVACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKAGGEEPSEE
DEMTKHIDPLHQLIQLFSRTALTEKCKLEEDHLYMAYADIMAKSCHDEEEDDEEEVKSFE
EKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGEMGPMVASTLKLGIAILNGGNSTVQQ
KMLDYLKDKRDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSVITHERGEKV
MQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFY
WYYSGKDVIDEQGQRNFSKAINVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLH
VFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNN
VEMILKFFDMFLKLKDLTSSDAFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSC
AETDENELLDYEEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSRLQTFLELAESVLNYF
QPYLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELF
VNFCEDTIFEMQLAAQMSDAAERSASKEDSEREKPDEESPEMGFFSVTTVRTALFALRYN
VMLLMKVLSMKSLKKQVKKAKKMTVKDMVTTLVSFYWSVLLGLLHFAFSVARGFFRITYN
SFLGGSLVEGAKTMKVSELLANMPDPTQDEVRGETEEGEKKHLDKTSPEEDLADLTVATD
DTDVLSDIFGLDLKREGGQYKLMPHNPNASLTDLLNTPVPQPPTLSPELRRRHQTKGSSS
STDNNEVAEETKSVPEKAERENGEKAQKKDEAVKRKVRLHYSRADEPDLQESAFWKKIIA
YQRKLLNYFARNFYNMRMLALFVAFAINFILLFYKVIHTFEVLFSASSDTSVRWDPLAGT
GTRPVTVHFVLEESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLVIFKREKEVARKL
EFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGHDRISELL
GMDKAALDFSDAHEKKKPKRDSSLAAVLNSIDVKYQIWKLGVVFTDNSFLYLAWYMSMSI
LGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFR
KFYNKSEDGESPDMKCDDMLTCYMFHMYVGVRAGGGIGDQIEDPAGDEYEIYRIIFDITF
FFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTL
QEHNLANYLFFFMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN
NT seq 14574 nt   +upstreamnt  +downstreamnt
atgacagacggcgaagccgaagatgagatccagttcttacggaccgatgatgaggtggtc
ctccagtgctccgccaccgtccagaaggagcagcagaaactctgtctggccgctgagggc
ttcgggaacagactatgtttcctcgagtccacgtccaactcaaagaatgttccgccggat
ctgtccatatgtacgtttgtgctggagcagtcgctgtcggtgcgagcactgcaggagatg
ctggccaacactgaggagcgagcggaagggacggcgcagggcggaggtcaccggacgctg
ctctacggtcacgcggtcttactgagacactcctacagcgggatgtatctgtgctgtctg
tctacggctcgctcgtccaccgacaaactggcttttgatgtggggcttcaggaagacaca
acaggtgaggcgtgttggtggaccatccaccccgcatccaaacagaggtcagagggcgag
aaggtgcgggtgggtgacgatctcatcctggtcagcgtgtcgtctgaacgttacctgcac
ttgtcgtatggtaacggcagtttgcacgtggacgcggctttccagcaaacgctctggagc
gtcgcgccgatctgctccggcagtgaagtggctcagggcttcctaattggtggagatgtt
ctgcggctgctgcatggtcacatggacgagtgtttgaccgtcccgtcaggagaacatgga
gaggaacaacgcaggacggtgcattacgagggtggagccgtgtccatccacgccagatcc
ctgtggaggctggagacgctccgagtcgcgtggagcggcagtcacatccgctggggtcag
ccgtttcgcttgcgtcacgtgaccaccgggaaatatctcagcatgatggacgatcaaggg
ctcctgctaatggacaaggagaaagcggacgtcaaatcgacggctttctgcttccgttcc
tcaaaagagaagctggactttggcctgaggaaggaggtggatgggatgggcgccccggac
atcaaatacggagactcggtctgctacatccagcacgtggacgccggactctggctcaca
taccagtctgtggacgccaagtgtgcccgcatgggcggcgtccagaggaaggccatcatg
catcatgagggtcacatggatgacggattgacgctctcgcgatcgcaaaacgaggagtcg
cgcaccgccagagtcatccgcagcacggtgttcctgttcaaccgcttcatcagtaagaag
gggaagacgtccaccctcgatctgcccatcgaatcggtcagtctgagccttcaggatctg
atcggatacttccagcctcccgatgagcacctggagcacgaggacaaacagaaccgactc
cgagcgctcaagagcagacagatcctgttccaggaggagggaatgatcaacctggtgctg
gagtgtatcgatcgtttgcatgtctacagcagtgcggctcattttgcagacgtggccggt
aaagaggctggacaatcctggaagtccatcctgaactccctctacgagctcctcgctgct
ctgatcagaggaaacaggaagaattgtgcccagttctccagctctctggattggctgatc
agtcgtctggagaggttggaagcgtcatctgggattctggaggttctgcactgtgttctg
gtggagagtccagaagctctgaacatcattaaagagggacacatcaaatccatcatctca
ctgctggacaaacatggacgcaaccacaaggttctggacgtcctgtgttctctgtgcgtg
tgtcacggtgtggcggttcgctccaatcagcacctgatctgtgataatctgctgcccggc
agagacctgctgctgcagacgcgtctcgtcaatcacgtcagcagcatgaggcccaatatc
ttcctgggtgtgagcgaaggctccgctcagtacaggaagtggtattatgagctcatcgtg
gaccacgtggagccattcatgacggctgaagccactcacctgcgggtgggctgggcctcc
acacagggctactggccgtatccgggcggaggagagggctggggcgggaacggcgtcggg
gacgacctctactcgtatggctttgatggccttcacctgtgggcaggttgcgtggcgcga
tcggtcagctcacccaatcagcacttgctgcgggccgaggacgtggtcagctgctgtctg
gatctcagcgctcccagcatctccttccgcatcaacggccagccggtccagggaatgttt
gagaacttcaactcagacggactctttttccctgttgtgtccttctccgctggagtcaaa
gtgcgcttcctgttgggcggtcgtcatggcgagttcaagttcctgcctccatccggttac
gctccgtgtttcgaggcggttttaccgcgagagaagctgagagtggagcacagtcaggag
tataaacatgatcacgggaaaacacgtgacctcctcggacccacggtcacgctgtcacag
gcggccttcacgccaacacctgtggacaccagtcagatcgtgttgccaccacatcttgag
cggatccgagagaagctggcagaaaacatccatgagctgtgggtgatgaacaagatcgat
ctcggatggacctacggaacggtaagagatgataataaacggcagcatccgtgtctggtc
gagttctccagacttcctgaacaagagcgcagctacaaccttcagatgtctcaggagacg
ctcaagactctcttggcactgggctgccatgttggcgtggcggacgaacgagcggcagag
aaagtcaaaaatctcaagctttcagccaaatatgagctctccagtgggtataaaccagcg
ccgatggacctgagccacatcaaactggcgtctacacaggaggccatggtggacaaactg
gcagagaatgctcacaacgtctgggccagagaccgcatacggcagggctggacctacggc
gtacagcaggacattaagaacaggagaaaccctcgcctcgttccgtacgttcttctggac
gagaggaccaagaaatcaaacaaggacagtctgcgggaagctgtgcggacactgctggga
tacggatacaacctggaagctccggatcaagaccatgcggatgcgggtaatctgtctgcc
gaacgcttccggatcttccgagcggagaagacgtacagcgtgagtggagggaagtggtac
ttcgagctggaggtggtgacggcgggcgagatgcgggtgggctgggcgagacccggctgt
ctgccggacctggagctgggctcagacgagcaggccttcgtcttcgatggattcaaggct
cagcgctggcatcagggcaacgagcacttcggccgctcctggcagtctggagatgtggtg
ggatgtatggtggacatgaacgaacgcaccatgatgttcacgctcaacggcgaggtgctg
ctcgatgactccgggtccgagctcgccttcaaagactttgaagtttgggacggtttcatc
ccggtctgtagtctgggcatctgtcaggtgggccgtatgaacttcgggaaggacgtgagc
acgctgaagtacttcaccatctgcggcctgcaggagggctacgaacccttcgccgtcaac
atgaaccgagatctgaccatgtggatcagcaaacggctgcctcagttcatccctgccccg
ctcaaccacgagcacatagaggtcacgaggatcgacgggacggtggagagcccaccgtgc
ctaaaggtcacccagaggtcattcggctcacagaacagtaacacggacatcatgttctat
cgtctcagcatgcccatcgagtgctcggaggcattcctgcgatcgcctggcgggacgcta
gcagccaacggcagcttcttctctcccaagagagacctggaggagcttctgtctctgtct
gtgtgtcagtattactactcggtgaggatcttccctgggcaggagccggccagtgtttgg
gtcggatgggtgacctcagactttcatcagtatgatccagcctttgagctcagcaaggtc
cgaacagtcactgttaccctgggagacgagaagggcaaagttcacgagagcattaagcgc
agtaactgctacatggtgtggggcggcgagtgcagcagtcccagtcagggccgcaataat
aacggcctagagatcggatgtttggtagatactgccaacggcctcctcagcttcacctcc
aacggcaaagagctcagcacctactaccaggtggagcccagtactaaactcttccctgca
gtgtttgcgcaggcgacaagtccaaatgtcttccagttcgaactgggacgcatcaagagc
gtcatgccgctctctgcagggctttttaaaagcgaacggaagaacgcggttcctcagtgt
ccgccgcggttacacgtgcagttcctcacgcctgtgttatggagccgtgtgcccaatcag
ttcctgaggtctgaggtcaccagggtcaatgagagactgggctggatggtgcagagttca
gaaccgctgcagttcatgaccctccatatacctgaggagaacaggtctctggatattctg
gagctgacggagcagcgcgacttgctgaagttccacttccacacgctgcgcttgtattcg
gccatctgtgcactgggaaacaaccgtgtggctcacgcgctctgcagtcacgtggatgag
gcgcagctcctctacgccatccagaacaaatacatgcctggcctcctgcgcactggttac
tacgacctgctcatcgacatccacctgagcagctatgccaccgcacgccttatgatgaac
tctgagtacattgttcccatgacggccgagaccaagagcatcacgctctttcccaatgaa
aagaagaagcacgggctgccgggcatcggcctgagcacgtcgctgcaaccgcgcatgcgc
ttctcctcgcccagcttcgtgggtcaccacggcacggttgctgggagcgactgcttccag
tacagccctgagttcccgctggagacgctgaagagccgtacgatggagatgctgacggag
gcggtgcgggaaggcagcttacacgtgcgcgatcccgttggcgggagcacagagttcctg
ttcgttccgctcattaaactcttctacacgctcctgatcatgggcatcttccacaacgga
gacctgaagaccatcctgcagctgatcgagcccagcgtgttctcgcaggacggtggcggc
ggggcgactgaggcggaggacggcagtgggcggggccggctggaagggggcggggctgag
gaacacggtctgagaggaaagatgccaaaagaaggacttttacagatgaagcttcctgag
cccgtcaaactccagatgtgtcacctgctgcagtacctgtgcgactgtcaggtgcgtcac
cgcattgaggctgtggtcgccttctccgacgactttgttgcaaatcttcaggataaccag
cgtttccgctataatgaagtgatgcaggcgctgaacatgtctgctgctctgacggcacgc
aaaaccaaagagttccgctcgcctccacaggaacagatcaacatgctgctgaattttaag
gatgagaagcaggattgtccatgtcctgaggacatccgtgaacagctgctagacttccat
gaagatctcatgacacactgcggcattgagatggatgatgataaatcaggagacggagat
gatttcaccatcaggggtcgtctgatgtctctggtggagaaggtgacctacctgaagaag
aaaatgactgatctaccaaagaaaaagaaatcaaagaaacccagcacgcttcagcagctg
atctctgagaccatggtccgctgggcgcaggagtcggtcatcgaggacccggagctggtg
cgggccatgttcgtgttactccaccgtcagtacgacggcatcggcgggcaggtgcgagcg
ctgcccaagacctacaccatcaacgccgtctccgtggaggacaccatcaacctgctggcg
tctctgggacagatccgctctctgctcagcgtcaggatgggccgcgaggaggagaaactc
atgattcatgggctcagtgacatcatgaataacaaggtgttttaccagcatccgaacctg
atgagagcgctcgggatgcacgagactgtcatggaggtgatggtgaacgttctgggcgga
ggagagtccaaggaaatcacgtttccaaagatggtggccaactgctgccggttcctgtgc
tacttctgtcgaatcagccgtcagaatcagaaggccatgttcgatcatctcagctacctg
ctggagaacagcagcgtgggacttgcatctccgtccatgcgaggatccactcctctggat
gtggccgctgcgtcagtgatggataataatgaactggctctggcgctgagagaaccggac
ctcgagaaggtggtccagtatctggccggctgtggtcttcagagctgcgtgatgctgatg
tctaaaggatatcctgacattggctggaacccggtggaaggcgaacgatacctggacttc
ctccgatttgcagttttctgtaacggtgagagtgtggaggagaatgctaacgtggtcgtg
cggctcctgattcggcggccggagtgttttggccccgccctgcgtggagagggtggaaac
gggctgctggcagcaatggaggaagccataaagatctcagaagatcccagccgagatgga
ccgtcgcccaccacagaggagagcaggacgcttagtgatgtgatggaggaagaagaagat
gacaccattcacatgggaaacgctatcatgaccttctacgcagctcttatcgacctgttg
ggccgctgcgctcccgagatgcatctgatccacgctgggaagggagaggccatccgtatc
cgagccatcctgcgctctctcattcccattgaggatctggtgggagtgatcagcatcccg
ttcctgatgcccacactggctaaagacggttccgtgatcgagccggatatgtcagcgggg
ttctgtcctgatcacaaagcagccatggttctgttcctggaccgggtttacggcatcgag
gaccagaacttcctcctgcacctgctggaagtaggtttcctgcctgacctcagagccgcc
gcctcattggacacggcggctctgagcgccacagacatggcgctggctctgaaccggtac
ctgtgcacggcggtcctgcctctgctcaccaaatgcgctcctctgttcgcggggacggag
ccgttcgcgtctctcatcgactctctgctgcacaccgtctacagactgtctaaaggctgc
tgtctcaccaaagctcagagagacgccatcgaggagtgtctgctggccgtgtgtgggaaa
ctgcgtccgtcgatgatgcagcatctgctgcggcgtctggtgttcgatgttcctgtgctc
aacgaacacacgaagatgcctctgaagctcctgaccaatcactacgagcgctgctggaag
tactactgtctgtccggagggtggggaagcttcggcgccgcgtccgacgaggagctgcat
ctgtccagaaaactcttctggggaatctttgacgctctggccagaaagaagtatgatgtg
gagttgttcaagctggctctgccgtgtctgagcgcagtggccggagctttacctcctgat
tacatggagtcaaactatgtggccatgatggagaaacagtcgtctatggacgccgaagga
aacttcaacccgcagcccgccgacaccagcagcgtcgttgttcctgagaagctcgatcat
ttcatcaataaatatgcagaatattcccatgagaaatggtccatggagaagtttgccgtt
ggctggattcatggagagcagatgtgtgaatcttctaaagttcatccactgctgaagccc
tacaagtgtctgtctgagaaggataaggaggtttaccgctggccaatcagagagagtctg
aagacgatgctgtcatggggctggagcatcgagcggacgaaagacagcgacgcgtccacc
ttacacagccgcacacgccggatctcactgtccagtcagggtgctcatggtttcagcccg
cggcctgtcgacatgagcaacgtgacgctgtccagagacctgcattcgatggcggagctg
ctggccgagaactatcacaacatttgggctcagaagaaaaaactggagctggaagccaaa
ggaggaggaagtcatccattactggttccttacgacactttaactgccaaagagaaatcc
aaagaccgggagaaagcacaagacatcctgaagttctttcagatcaatggatacagcgtc
tcaagggcgatgaaagaacaggatctggacactccgtctatagagaaacgcttcgcatac
acgtttctgcagcagctgatcacgtatgtggacgaagctcacggacacatgctggagttc
gatgctggaattcgactgaaaggggagaaaatccctcacgagcagcaggtcaaattcttc
gggaaggtcgtgctgccgctggtggaccagtacttcaaaaaccaccggctctacttcctg
tccaccgctgttcgaccaatcagcagcggcggccacgcctccaataaagagaaggagatg
gtgaccagcctgttctgcaaactgggcgttctggtgcggcaccggatctcattgtttggg
aatgacgccacctccattgtgaactgcctgcacatcctgggacagacgctggacgcccgg
actgtgatgaaaaccggtcaggactctgtcaaagcggctctgagggcgtttttcgataac
gcatcagaagatttggagaaaaccatggaaaacctgcggcagggtcagttcacacacacg
cggatgcagcccaagggcgtcacacagatcatcaactacacgacggtcgcgctgctgccg
gtgctgtcctcgctgttcgaacacatcgggcagaacctgttcggagaggatctcatcttg
gatgatgtccaggtttcctgctatcggatattaaacagtttgtactcacttggaaccagt
aaaagtatttatgttgagaggcagcgtccggctctcggtgagtgtctggccgcgttctcg
ggcgcgtttcccgtggccttcctcgagcccaatctgaacaaacacaacacatactccata
tacaactgcaaaggctccagagagagagcagcgttaggtctgccggctcaggtggaggag
gtgtgcgcgctggtgccgtctctggagcgggcgctgcaggagatcatggagctggccgag
tcgggcatgcgctacacgcagatgccgcacgtgatggaggtgctgctgcccatgctgtgc
agctacatgtcgcactggtgggaacacggacccgagagcgacccggagcgcggcgagagc
tgctgcacctcgctgacctcggagcacatgaacacgctgctgggaaacatcctgaagatc
atctacaacaacctgggcatcgacgagggagcctggatgaagagactggcagtgttttct
cagcccatcatcggtaaagccaagtctcagctgctgaagactcacttcctgccgctgatg
gagaagctgaagaagaaggcggcgacggtcctgcaggacgaggagcacatgaaggcggag
ggccggggcgagatgtcggagtcggagctcctcatcctggacgagttcaccatcctcgtg
cgagacctgtacgccttctacccgctgctcatacgcttcgtcgactacaaccgagcgaaa
tggctgaaggaaccgaacactgaggcggaggagttattccgtatggtggccgaagtcttt
atattctgggccaaatcacataactttaaacgagaagaacaaaactttgtggttcagaat
gaaatcaacaacatgtcctttctgataactgataccaaatctaaaatgtccaagggcggt
gtatcggaccaagagaggaagaagatgaagaagcgaggggatcgatattccctccagacg
tctctgatcgtcgccgctctcaagcgattgcttccggtcggactgaacatctgtgcgccg
ggagaccaggagctgatcggactcgccaagagccgcttcacacagaaagacactgaggac
gaggtccgagagatcatacgaaacaacctccacctgcaggggaagctggaggatcctgcg
atccgctggcagatggcgctgtataaagacatgcccaaccgcagcgaggactcgtcggac
cctgagaagactgtcgacagagtgctgaacatcgcacacgtgctcttccacctcgaccag
gttgaacatcctcagcgcagtaagaaggccgtgtggcacaagctgctgtccaaacagagg
aagagagccgtcgtggcctgtttcaggatggcgccactttacaacctgcccaggcacaga
gccgtgaacctgttcctccagggttacgagaagtcctggatcgagacggaagagcactat
ttcgaggacaagctgattgaggatttggccaaagcaggcggagaggagccgtcagaggag
gacgagatgaccaaacacatcgatcccttacaccagctcatacaactcttcagcagaacc
gcgctgaccgagaaatgtaaactagaggaggatcatctctacatggcgtacgctgacatc
atggccaagagctgtcatgatgaagaggaagacgacgaggaagaggtgaagagttttgag
gagaaggagatggagaagcagaagctgctgtatcagcaggccagacttcatgaccgcggc
gccgcagagatggtgctgcagaccatcagtgccagcaaaggagagatggggccgatggtg
gcctccacgctcaagctgggaatcgccatacttaatggaggaaactccacagttcagcag
aaaatgctggactacctgaaagacaaacgagacgttggatttttccagagtctggcggga
ctcatgcagtcatgcagtgttctggatctgaacgcgtttgagaggcagaataaagccgaa
ggtctcgggatggtgacggaggaaggatcagtcatcactcatgagcgtggtgagaaggtc
atgcaagatgacgagttcacctgcgacctcttccgcttcctccagctgctctgtgaggga
cacaattcagatttccagaactacctgcgaacgcagacgggtaacaacacgacggtcaac
atcatcatctcgacggtggattatctgctccgagtccaggagtccatcagtgatttctac
tggtactattctgggaaagacgtcatcgatgaacaaggccagcggaacttctccaaagca
atcaatgtagccaaacaagtcttcaacactctcacagagtacattcagggcccttgcacg
gggaatcagcagagtctggctcacagtcgcctgtgggatgcagttgttggtttcctgcac
gtttttgcacatatgcagatgaagctgtctcaggattcaagccaaatcgagctgttgaag
gagctcatggatcttcagaaggacatggttgtgatgctcttgtccatgttggagggaaat
gttgtgaatggtaccattggaaagcagatggtggacatgttggtggagtcctcaaacaac
gtagagatgattctgaagttctttgacatgttcctcaaactgaaagatctgacgtcatca
gatgccttcaaagagtacgaccctgatggcaaaggcgtcatctccaagagggatttccac
aaggccatggagagccataaacattacacccaatctgagacagaattcctgctctcctgt
gcggaaacagatgaaaatgagctcttggactacgaagagttcgtcgaacgcttccacgag
ccggcgaaggacatcggcttcaacgttgccgttctcctgaccaacctctcggagcatatg
ccccatgactctcgcctccagaccttcctggagctggccgaaagcgtgctgaactacttc
cagccgtacctgggccgcatcgagatcatgggcagcgccaagcggatcgaacgagtgtac
tttgagatcagcgagtccagtcgcacccagtgggagaagccacaggtcaaggagtccaaa
cggcagttcatcttcgatgtggtgaacgaaggtggtgagaaggagaaaatggagctcttc
gtcaacttctgtgaagacaccatctttgagatgcagttggctgcgcagatgtctgacgcc
gctgagcgctcggctagcaaagaggacagcgagagggagaaacccgatgaggagagtccc
gagatgggcttcttctccgtcaccaccgtgcgaacagctctcttcgctctacgatacaac
gtgatgctcttaatgaaggtgctgtccatgaaaagcctcaagaagcaggtaaagaaagcc
aagaagatgacggtgaaggacatggtgaccacgctagtgtccttctattggagcgtcctg
ctgggtctgctgcacttcgccttcagcgtcgctcgaggattcttccggatcacatacaac
agctttctcggggggagtctggtggagggcgccaagaccatgaaggtgtcggagctcctg
gccaacatgcccgacccgactcaggacgaagtgaggggagagacggaagagggcgagaag
aaacaccttgacaaaacctcacccgaggaagaccttgccgatctgactgtggccacagac
gacaccgacgtcctgtccgatatattcggtttggatctgaagagagagggagggcagtat
aaactgatgcctcacaatccaaatgccagcctcacggatttgctcaatacacctgtcccg
cagccacccacactctcacctgagctccgcagacgacaccagacaaagggctcgtcatcc
tcaactgacaacaatgaagttgcggaggagaccaaatcagtgcctgagaaagccgaaagg
gaaaatggagagaaagcacagaagaaggacgaagcggtgaagcgcaaggtcagactgcac
tactccagagcagatgagcctgatctgcaggagtcagccttctggaagaaaatcatcgct
tatcaacgcaagctgctgaactattttgcacgaaatttctacaacatgagaatgttggct
ttgtttgtggcctttgcaatcaacttcattctgctgttttacaaggtaattcacactttt
gaggtgttgttcagcgcgtcctcggacaccagcgtgcggtgggaccctctggccggcacc
ggcactcgcccggtcactgtgcactttgtgctggaggagagcagcggatacatggagccc
accctgcggatcctagccatcctgcacacggtcatctccttcttctgtatcatcggctac
tactgcttgaaggttcctctggtgattttcaagcgagagaaggaagtggccagaaagctg
gagtttgacggcctgtacatcactgaacagccctcagaagatgatattaaaggccagtgg
gaccggctggtcatcaatacacagtccttcccaaacaattactgggataaatttgtgaag
cggaaggtgatggataagtatggagagttttatggacatgatcggatcagtgagctgctc
gggatggataaagccgcgctggacttcagtgatgcccacgagaaaaagaaaccaaagaga
gacagttcactggccgcagtactgaactcaatcgatgtgaagtatcagatctggaagctg
ggtgtcgtcttcacagataactcgttcctgtatctggcctggtacatgagcatgtccatc
ctcggtcactacaataacttcttcttcgctgcccatctgctggacatcgccatgggcttc
aagacgctcaggaccatcctgtcttctgtcacgcacaatggcaaacagctggtcctgact
gtcggtctgctggcggttgtggtgtatctctacaccgtagtggctttcaacttcttccga
aagttctacaataagagtgaagatggagaatcaccagacatgaagtgtgacgacatgcta
acgtgctacatgttccacatgtatgttggcgttcgtgccggcggtggcatcggcgatcag
atcgaagatccggccggcgacgagtacgagatctatcgcatcatctttgacatcaccttc
ttcttcttcgtcatcgtcatcctcctggccatcattcagggtctgatcattgatgcgttc
ggtgagctgagagaccagcaggagcaggtgaaagaggacatggagacgaagtgcttcatc
tgtggaataggaaacgattacttcgacacggttcctcacggctttgagacgcacacgctg
caggaacacaatctggccaactatctatttttcttcatgtatctcatcaacaaggatgaa
acggagcacaccggccaggagtcgtacgtttggaaaatgtaccaggaacgttgctgggaa
ttctttcccgctggcgactgtttcaggaaacaatacgaggaccagctcaattaa

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