Cellulosilyticum sp. WCF-2: EKH84_07725
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Entry
EKH84_07725 CDS
T06333
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
cew
Cellulosilyticum sp. WCF-2
Pathway
cew00270
Cysteine and methionine metabolism
cew00480
Glutathione metabolism
cew01100
Metabolic pathways
cew01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
cew00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
EKH84_07725 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
EKH84_07725 (gshAB)
Enzymes [BR:
cew01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
EKH84_07725 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATPgrasp_ST
Dala_Dala_lig_C
ATP-grasp_3
GARS_A
Ribosomal_L16
DUF1203
Rimk_N
Motif
Other DBs
NCBI-ProteinID:
QEH68286
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Position
1756608..1758941
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AA seq
777 aa
AA seq
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MLNQLKQLFNREELLAASIGIEREGLRVTPEGKLAMSKHPAVFGDKLKNPYITTDFSESQ
VEIITPNLDSSQKAYDYLNILYDIVALNIEDEYIWPGSMPCDIPADEHIPIAEYRDCKTC
QEARLYREELLKKYGGKKQLISGIHYNFSFEENFIQRLYEAEDTHLNYQLFKDSIYLKMA
RNYLRYRWLLIYLLGATPVFHKTYATECTRYLNKVDEESFTNPGAVSYRNGECGYKNHTD
LYPDYSSVEAYAKSIERFVADGMIQSHKELYSQIRPKAKDNTRLLESLKQEGILYIEVRS
IDNNPFEKGGISLEDLEFLHLFMLYLLIKEESKEELINWQEEATNNQRLIAKGGRLEVWL
SKEGKEITKTEWALEILDEMKVMEGTLDLNRAEVIDEMVKKVCDPERTYAAKITELSKQK
GYLQSQLELAEIYKKDAYANRYKLYGYDDMELSTQILMKEAIKRGIKVEVLDRSDNFIAL
TQGTHTEYVKQATKTSKDSYMTMLMMENKTVTKKVLEKHQVCVPKGIEVFKGQGLELAVK
RYANKPIVVKPKSTNFGKGISIFTQGASEVDIKRALEIGFEHDDTVLIEEFAKGKEYRFL
VIGDQVAGVLHRVPANVIGDGAHTITQLVAIKNQDSLRGRGYKTPLEKINLDASSALFLK
QSDLDFDYIPAEGEVVYLRENSNISTGGDSIDYTDDIPEYFKEIAVRAAKAVGAKFCGVD
MMLEDYRDEKAPYAIIELNFNPAIHIHSYPYKGTERQIAEQVLKVLEFNLESDCTQY
NT seq
2334 nt
NT seq
+upstream
nt +downstream
nt
atgcttaatcaattaaagcaattatttaatagagaagaattattagctgcaagcattggt
attgaaagagaagggcttagagtaacacctgaaggaaagcttgctatgtccaagcatccg
gctgtatttggggataaacttaaaaacccatacattactacagatttttctgagagccag
gtagagattattacacctaatttagatagtagtcaaaaagcatacgattacttaaatatt
ttatatgatatagtcgcacttaatatagaagatgaatatatatggccgggttctatgccg
tgcgatataccagcagatgaacatattcctattgccgaatatagagattgtaaaacttgt
caagaagcgaggctttatagggaggagctacttaagaagtacggagggaaaaagcaactt
atttcaggaatacattataatttttcctttgaagaaaactttatacaaagactttatgaa
gcagaagatactcacttaaattatcagctattcaaagatagtatttatttgaagatggca
agaaattatttaaggtatcgttggttacttatttatttattaggagcgacacctgtattt
cataaaacctatgctacagagtgtacacgctatttaaataaggtagatgaagaaagcttt
acaaatccaggggctgtatcttatcgtaatggtgaatgtggttataaaaatcatactgat
ctttatcctgactactctagtgtagaggcctatgcaaaaagtattgagagatttgtagca
gatggcatgattcaaagtcacaaagaactttatagtcaaatcaggccaaaggcaaaggat
aatacaagactactggagtccttaaaacaagaaggtatcttatatattgaagtgagaagt
attgataataatccttttgaaaaaggcggtattagcttagaagacttagagtttttacac
ttatttatgttataccttctcataaaagaagaaagtaaagaagagctaattaattggcag
gaagaagctactaataatcagcgtttaattgccaagggtggaagattagaggtttggtta
agtaaggaaggaaaagaaattacgaagaccgagtgggctttagaaattttagatgaaatg
aaagtgatggaaggaactttagatcttaacagggcagaagttattgatgaaatggtcaag
aaggtatgtgatcctgagcgtacttatgcagctaaaataacagaactctctaaacaaaaa
ggctatttacagagccaattagaactagcagaaatttataaaaaagatgcttatgcgaac
cgttataaactatatggttatgatgatatggaactttctacacaaatccttatgaaagaa
gctattaaaagaggaataaaagtagaagtattagatcgtagtgacaactttattgccctt
actcaaggaacacataccgaatatgtgaaacaggctaccaagacatctaaagatagttat
atgactatgctgatgatggaaaataaaacagttactaagaaggtgttagagaagcaccag
gtttgtgtaccaaaaggtattgaagtttttaaaggacaaggcttagagttagcagttaag
cgttatgccaataaacctattgttgttaaaccaaaatctacgaatttcggtaaaggcatt
agtatttttacacagggagccagtgaagtagatatcaaaagggcgcttgagataggcttt
gaacatgatgatacagtgttaattgaagagtttgctaaaggtaaggagtaccgattcctt
gtaatcggagatcaagtggcaggagttcttcaccgcgtaccggccaatgttataggtgat
ggagcacatacgataacacagttagtagctataaaaaatcaagatagtttaagagggaga
ggttataaaacaccattagaaaaaattaacttagatgcaagtagcgctttattcctaaaa
caaagcgatttggatttcgactatattcctgctgaaggagaggttgtttatttgagggaa
aattctaacattagcacaggtggagatagcattgattatacagatgatattccagaatac
tttaaagagatagctgttcgtgcagccaaagcagtaggtgctaagttttgtggtgttgat
atgatgctagaagattatagagatgaaaaagcaccttatgcaattattgaacttaacttt
aatcccgctattcatattcattcttatccttataaaggaacagaacgtcaaatagctgaa
caagttttaaaggtactagaatttaatttagagtctgattgcactcagtattag
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