Canis lupus familiaris (dog): 100686499
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Entry
100686499 CDS
T01007
Symbol
GLS2
Name
(RefSeq) glutaminase liver isoform, mitochondrial isoform X1
KO
K01425
glutaminase [EC:
3.5.1.2
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00220
Arginine biosynthesis
cfa00250
Alanine, aspartate and glutamate metabolism
cfa00470
D-Amino acid metabolism
cfa01100
Metabolic pathways
cfa04724
Glutamatergic synapse
cfa04727
GABAergic synapse
cfa04964
Proximal tubule bicarbonate reclamation
cfa05206
MicroRNAs in cancer
cfa05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
100686499 (GLS2)
00220 Arginine biosynthesis
100686499 (GLS2)
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
100686499 (GLS2)
09150 Organismal Systems
09155 Excretory system
04964 Proximal tubule bicarbonate reclamation
100686499 (GLS2)
09156 Nervous system
04724 Glutamatergic synapse
100686499 (GLS2)
04727 GABAergic synapse
100686499 (GLS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100686499 (GLS2)
05230 Central carbon metabolism in cancer
100686499 (GLS2)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.1 In linear amides
3.5.1.2 glutaminase
100686499 (GLS2)
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Gene cluster
GFIT
Motif
Pfam:
Glutaminase
EF-hand_14
Ank_4
Ank_2
Ank
Ank_5
Ank_3
Ank_KRIT1
Motif
Other DBs
NCBI-GeneID:
100686499
NCBI-ProteinID:
XP_003431516
Ensembl:
ENSCAFG00000000131
VGNC:
41277
UniProt:
A0A8C0QF91
A0A8I3N750
LinkDB
All DBs
Position
10:complement(785318..800983)
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AA seq
602 aa
AA seq
DB search
MRSLRALQEALSGAGAQCRLGGWGRPSRSPLLGGGVRHHLSEAAALGRETPHSHQPQRQD
HDSSESGMLSRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLRDCMSQMRRMVR
ESSSGGLLDRDLFQKCVSSNIVLLTQAFRKKFVIPDFEEFTSHVDRIFEDAKELTGGKVA
AYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTEYVHK
FVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAG
NEYIGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESG
SVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGA
ILLVVPNVMGMMCLSPPLDKLGNSHRGISFCQKLVSLFNFHNYDNLRHCARKLDPRREGG
EVRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIE
ACKVNPFVKDRWGNVPLDDAVQFNHLEVVKLLQDYQDSYTPSETQAEAAAEALSKENLES
MV
NT seq
1809 nt
NT seq
+upstream
nt +downstream
nt
atgcgctccctcagggctctgcaggaggcgctgagcggggccggcgctcagtgccggctg
ggaggctggggccgcccgagccggagccctctccttggcgggggcgtccggcaccacctc
agtgaggccgcggcgctgggcagggagacgccgcacagccaccagccgcagcgccaggat
catgattcatcagagagtggcatgctatcccgcctgggtgatctcctcttctacactatt
gctgaaggacaggaacgaatccccatccacaagttcactactgcactgaaggccactgga
ctgcagacatcagatccccggctccgggactgcatgagccagatgcgccgcatggttcga
gagtccagcagtggtggcctcttggaccgagatctcttccaaaagtgtgtgagcagcaac
attgtgctcctgacccaggcattccgaaagaagtttgtcattcctgattttgaggagttc
acgagccatgtggatcgcatctttgaggatgccaaagagctcactggaggcaaagtggcg
gcttatatccctcagctggccaagtccaatccagacctgtggggcgtctccttgtgcact
gtggatggtcaacggcactccgtgggccacacaaagattcccttctgcctgcagtcctgt
gtgaagcccctcacctatgctatctccataagcaccctagggactgagtacgtgcacaag
tttgtgggcaaggagcccagtggcctacgctacaacaagctgtccctcaatgaggaagga
atcccccataaccccatggtcaatgctggtgccattgtcgtgagctccctgatcaagatg
gactgtaacaaagcagagaagtttgattttgtgttacagtatctgaacaaaatggctggg
aacgaatacataggtttcagcaatgccacattccagtcagagaaggaaacaggggatcgg
aattatgccatcggctattatctaaaggaaaagaagtgctttcctaagggggtggacatg
atggctgctcttgatctctatttccagctgtgctctgtggaggtgacctgtgagtcgggc
agcgtcatggcagccaccctggccaacggcgggatctgccccatcacgggggagagcgtc
ctgagtgctgaagcagtgcgcaacaccctcagcctcatgcactcctgtggcatgtatgac
ttctcgggccagtttgccttccacgtgggcctgccggccaagtcagctgtgtcaggagcc
atcctcctagtggtacccaatgtcatgggaatgatgtgtctgtcacctccactggacaag
ctagggaacagccataggggcatcagcttctgccagaagctggtatctcttttcaatttc
cacaactacgacaacctgaggcactgtgctcggaagttagacccacggcgtgaaggggga
gaagttcggaacaagactgtggtgaacctgttatttgctgcctatagtggagatgtctca
gctcttcgaaggtttgccttgtcagccatggacatggaacagaaagactatgattcccgc
acagccctgcatgttgctgcggctgaaggacacattgaagttgttaaattcctgattgaa
gcttgcaaagtgaatccttttgtcaaggacaggtggggcaacgttcccttggatgatgct
gtgcagttcaaccacctggaggttgtgaaactgctgcaggattaccaggactcctacaca
ccatctgagactcaggccgaggcagcggctgaggccctgtccaaagaaaacttagagagc
atggtgtga
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