Canis lupus familiaris (dog): 100855521
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Entry
100855521 CDS
T01007
Symbol
HMGCL
Name
(RefSeq) hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1
KO
K01640
hydroxymethylglutaryl-CoA lyase [EC:
4.1.3.4
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00280
Valine, leucine and isoleucine degradation
cfa00650
Butanoate metabolism
cfa01100
Metabolic pathways
cfa04146
Peroxisome
Module
cfa_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
100855521 (HMGCL)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
100855521 (HMGCL)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100855521 (HMGCL)
Enzymes [BR:
cfa01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.4 hydroxymethylglutaryl-CoA lyase
100855521 (HMGCL)
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GFIT
Motif
Pfam:
HMGL-like
Motif
Other DBs
NCBI-GeneID:
100855521
NCBI-ProteinID:
XP_003638949
Ensembl:
ENSCAFG00000013085
VGNC:
41712
UniProt:
A0A8C0LXZ1
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Position
2:72258838..72273447
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AA seq
325 aa
AA seq
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MAAMRKVVPRRLVGLASLRAVSTFSLGTFPKQVKIVEVGARDGLQNEKNIVSTSTKIKLI
DMLSEAGLPVIEATSFVSPKWVPQMADCAEVLKGIQKFPGINYPVLTPNIKGFQAAVAAG
AKEVTIFAAASEQFTKKNTNCSIDECLQRSDDIFRAAQAAGIPVRGYVSCVLGCPYEGKI
SPAKVVEVAKKIYSMGCYEISLGDTIGVGTPGVMKDMLSAVMHEVPVSALAVHCHDTYGQ
ALANTLMALQMGVSVVDSSVAGLGGCPYARGASGNLATEDLVYMLSGLGIHTGVNLQKLL
EAGTFICQALNRKTSSKVAQAACKL
NT seq
978 nt
NT seq
+upstream
nt +downstream
nt
atggcggccatgaggaaggtggtgccgcggagactggtgggcttggcgtctctccgggct
gtcagcaccttttctctgggtacttttccaaagcaagtgaaaattgtggaagttggtgcc
cgagatggactacagaatgaaaagaatattgtatctacttctacaaaaatcaagctgata
gacatgctttcagaagcaggactccctgttatagaagccaccagctttgtgtcccccaag
tgggttccccagatggctgactgtgctgaagtcttgaagggcatccagaaatttcctggc
atcaactacccagtcctgaccccaaatatcaaaggcttccaggcagcggttgctgctgga
gcgaaggaggtgaccatctttgcagctgcctcggagcagttcaccaagaaaaacaccaat
tgctccattgatgagtgtttacagaggtccgacgacatcttcagggcagctcaggccgcc
ggtatccctgtgcgtgggtatgtctcctgtgtgcttggatgcccctatgaaggcaagatc
tccccggctaaagtagttgaggtcgccaagaagatatactcaatgggctgctatgagatc
tccctgggggacaccattggtgtgggaaccccaggggttatgaaggacatgctgtctgcg
gtcatgcacgaggttcctgtgtctgctctggctgtccactgccatgacacctatggccag
gccctggccaacaccttgatggccttgcagatgggagtgagcgtggtggactcttccgtg
gcaggacttggaggctgtccctatgcacggggggcatctggaaacttggccactgaggac
cttgtctacatgctgtctggcttgggcattcacacgggtgtgaacctccagaagctcctg
gaagctggaacctttatctgccaagccctgaacagaaaaaccagttccaaagtggctcag
gctgcctgtaaactgtga
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