Canis lupus familiaris (dog): 403408 Help Entry 403408            CDS       T01007                                  Symbol PSEN1 Name (RefSeq) presenilin-1 isoform 1   KO K04505   presenilin 1 [EC:3.4.23.-] Organism cfa  Canis lupus familiaris (dog) Pathway cfa04310   Wnt signaling pathway cfa04330   Notch signaling pathway cfa04722   Neurotrophin signaling pathway cfa05010   Alzheimer disease cfa05022   Pathways of neurodegeneration - multiple diseases cfa05165   Human papillomavirus infection Brite KEGG Orthology (KO) [BR:cfa00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     403408 (PSEN1)    04330 Notch signaling pathway     403408 (PSEN1)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     403408 (PSEN1)  09160 Human Diseases   09172 Infectious disease: viral    05165 Human papillomavirus infection     403408 (PSEN1)   09164 Neurodegenerative disease    05010 Alzheimer disease     403408 (PSEN1)    05022 Pathways of neurodegeneration - multiple diseases     403408 (PSEN1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:cfa01002]     403408 (PSEN1) Peptidases and inhibitors [BR:cfa01002]  Aspartic peptidases   Family A22: presenilin family    403408 (PSEN1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Presenilin Motif Other DBs NCBI-GeneID:  403408 NCBI-ProteinID:  NP_001002943 Ensembl:  ENSCAFG00000016815 VGNC:  45085 UniProt:  Q6RH31 A0A8C0PFQ1 A0A8I3RZ86 Q56JJ5 LinkDB All DBs Position 8:46188004..46253311 Genome browser AA seq 466 aa AA seqDB search MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDSREQHSSERRRRGNPEPLSNGRPQGSSHQ VVEQDDEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTED TETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIY LGEVFKTYNVAMDYITVALLIWNFGVVGMIAIHWKGPLRLQQAYLIMISALMALVFIKYL PEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEG DPEAQRKVSKNSNYNAQSTESETQDPVTESDDGGFSEEWEAQRDSRLGPHHSTTETRAAV QELSSNILASEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLT LLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI NT seq 1401 nt NT seq  +upstreamnt  +downstreamnt atgacagagttacctgcacccctgtcctacttccagaatgcacagatgtccgaagacaac cacttgagcaatactgtacgtagccagaatgacagtagagaacagcacagcagtgaaagg cggcggcgtggcaaccctgagccattatctaacggacgaccccagggtagctcacaccag gtggtggaacaagatgatgaagaagatgaagagctgacattgaaatacggcgccaaacat gtgatcatgctttttgtccccgtgactctctgtatggtggtggtcgtggctaccatcaaa tcagtcagcttctatacccggaaggatggacagctaatctatacccccttcacggaagat actgagaccgtggggcagagagccctgcactcaattctgaatgctgctatcatgatcagc gtcattgttgtcatgactattctcctggtggttctgtataaatacaggtgctataaggtc attcatgcctggcttattatctcatctctattgttgctgttctttttctcattcatttac ttgggggaggtgtttaaaacctacaatgttgccatggactacattactgttgcgctcctg atctggaattttggtgtggtgggaatgattgcaattcactggaaagggccgctgcgactc cagcaggcatatctcattatgatcagtgccctcatggccctggtatttatcaagtacctt ccagaatggacagcgtggctcatcttggctgtgatttcagtatatgatttagtggctgtt ttgtgtccaaaaggcccacttcgtatgctggttgaaacagcacaggagaggaatgaaact ctttttccagctctcatttactcctcaacaatggtgtggttggtgaacatggcagaagga gatccagaagcccaaaggaaggtatccaaaaactccaattataatgcacaaagcacggaa agtgagacccaagaccctgtgacagagagtgatgatggtggcttcagtgaagagtgggaa gcccagagggacagtcgcctcgggcctcatcattctacaactgagacacgagctgctgtg caggagctttccagcaacatccttgccagtgaggacccagaagaaaggggagtaaaactt ggattaggagatttcattttctacagtgttctggttggtaaagcttctgcaacagccagt ggagactggaacacaaccatagcctgttttgtagccatattaattggtttgtgccttaca ttattactccttgccattttcaagaaagcattgccagctcttccgatctccatcactttt gggcttgttttctactttgccacagattatcttgtacagccctttatggaccaattagca ttccatcaattttatatttag

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