| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
cfa Canis lupus familiaris (dog)
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| Pathway |
| cfa04977 | Vitamin digestion and absorption |
| cfa04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:cfa00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
403453 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
403453 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
403453 (ABCC1)
04981 Folate transport and metabolism
403453 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
403453 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
403453 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:cfa02000]
403453 (ABCC1)
Enzymes [BR:cfa01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
403453 (ABCC1)
Transporters [BR:cfa02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
403453 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
6:complement(29219306..29353121)
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| AA seq |
1531 aa
MALRGFCSADGSDPFWEWDVSWNTSNPDFTKCFQNTVLVWVPCCYLWLCFPFYFLYLSRH
DRGYIQMTYLNKTKTALGFVLWIVCWADLFYSFWERSWGKILAPVFLVSPTLLGITMLLA
TFLIQLERRKGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDAEIDVFRDVTFYIYFS
LVLIQLVLSCFSDRPPLFSETIHDLNPCPESSASFLSRVTFWWITGLMVRGYRQPLESTD
LWSLNKEDTSEQVVPVLVKNWKKECAKSKRQQRKITYSSKDPAKPKGGSQVDVNEEAEVL
IVKTPQKEREPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFVNDKKAPD
WQGYLYTALLFICACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTV
GEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPLN
AVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLK
KSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNNILDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGANSITVKNATFTWARSDPPT
LSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQND
SLRENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLAR
AVYCDSDIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRLLVTHSISYLPQVDVIIV
MTGGKISEMGSYQELLARDGAFAEFLRTYASGDQEQAEQDDGLTGVSSPGKEVKQMENGM
LVTDVAGKQLQRQLSNSSSYSGDVSRHHTSTAELQKAGPKNEDAWKLVEADKAQTGQVKL
SVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTKIRLSVYG
ALGISQGITVFGYSMAVSIGGIFASRRLHVDLLQNVLRSPMSFFERTPSGNLVNRFSKEL
DTVDSMIPQVIKMFMGSLFNVIGACIIILLATPIASIIIPPLGLIYFFVQRFYVASSRQL
KRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLA
VRLECVGNCIVLFAALFSVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVA
VERLKEYSETEKEAPWQIQEMAPPSTWPQVGRVEFRDYGLRYRENLDLVLKHINITINGG
EKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDINIAKIGLHDLRVKITIIPQDPVLF
SGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSGLPDKLNQECAEGGENLSVGQRQLVCL
ARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVL
DKGEIRECGQPSDLLQQRGLFYSMAKDAGLV |
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| NT seq |
4596 nt +upstreamnt +downstreamnt
atggcgctccgcggcttctgcagcgccgacggctccgaccccttctgggagtgggatgtc
tcgtggaataccagcaaccccgacttcaccaagtgctttcagaacacggtcctcgtgtgg
gtgccttgttgttacctctggctctgcttccccttctacttcctctatctctcgcgccat
gaccgaggctacattcagatgacatatctcaataaaaccaaaactgccttgggatttgtg
ctatggatcgtctgctgggcagacctcttctactctttctgggaaagaagttggggcaaa
atcctggccccggtgtttctggtcagcccaaccctcttgggcatcactatgctgcttgct
acctttttaattcagctcgagagaaggaagggagtccagtcctcggggatcatgctcact
ttctggcttatagccctactgtgtgcccttgccatcttgagatccaaaatcatgactgcc
ttaaaagaggatgctgaaatcgacgtgtttcgtgatgtcactttctacatttacttttcc
ctcgtgctgattcagctcgtgttgtcctgcttctcagaccgaccgcccctgttctctgaa
accatccatgacctcaatccctgcccggagtccagtgcctctttcctttccagagtcacc
ttctggtggatcacagggttgatggtccgaggctaccgccagcccctggaaagcactgac
ctttggtccctgaataaggaggacacgtcagaacaagtggtgcctgttctggtaaagaac
tggaagaaggagtgtgccaaatccaaaagacagcagaggaagatcacatactcctccaag
gatcctgccaagccaaaagggggctcccaggtggacgtgaacgaggaggctgaggtgttg
attgttaagaccccacagaaggagcgcgagccgtctctattcaaggtgttatacaagacc
ttcgggccctacttcctcatgagcttcttattcaaggccctccatgacctgatgatgttt
gctggcccagagatcttaaagttgctcatcaacttcgtgaacgacaagaaggccccggac
tggcagggctacctgtacactgcgctgctcttcatctgcgcctgcctgcagaccctcgtg
ctgcaccagtacttccacatctgcttcgtcagcggcatgaggatcaagacagccgtcatc
ggggccgtgtaccggaaggcattggtgatcaccaactcagccagaaaatcctccaccgtc
ggggagattgtaaacctcatgtctgtggacgcccagcggttcatggacctggccacgtac
attaacatgatctggtcagctcctctgcaagtcatccttgctctctacctcctgtggctg
aacctgggcccgtctgtcctggctggggtggctgtgatgatcctcatggttccgctcaat
gccgtgatggccatgaagactaagacctaccaggtggcgcacatgaagagcaaagacaac
cggatcaagctgatgaatgagattctcaacgggatcaaagtgctaaagctgtacgcctgg
gaactggccttcaaagacaaagtcctggccatcaggcaggaggagctcaaggtgctgaag
aaatcggcctacctggccgccgtggggaccttcacctgggtctgcacgccatttctggtg
gccttgtctacatttgctgtctacgtgaccgtcgacaagaacaacatcctcgacgcccag
aaagctttcgtgtccttggccttgttcaacatcctccggttccctctgaatattctcccc
atggtcatcagcagcatcgtgcaggcaagtgtctccctcaaacgcctccggatcttcctg
tctcacgaggagctagagcctgacagcattgagcgaaggcccgtcaaagacggcgggggc
gccaacagcatcactgtgaagaatgccacgttcacgtgggcccggagcgaccctccaacg
ctaagcggcatcaccttctccattccggaaggttccttggtggccgtggtgggccaggtg
ggctgcggaaagtcgtctctgctctcggcactcctggcggagatggacaaggtggagggg
catgtggctatcaagggctcagtggcctacgtcccccagcaggcctggattcagaatgat
tctctccgagaaaacatccttttcggacgccagctacaggaacggtattataaggctgtg
attgaagcctgtgccctcctcccagatctggaaatcctgcccagcggggaccggacagag
attggtgagaagggcgtgaacctgtctgggggccagaagcagcgagtgagcctggcgcgg
gccgtgtactgtgactctgacatctacctcttcgatgatcctctgtcagcagtggatgct
catgtgggaaaacacatatttgaaaatgtgattggccccaaggggatgctaaagaataag
acgcggctcctggtcacgcacagcatcagttacctgccccaggtggatgtcatcattgtc
atgaccggtggcaagatctcggagatgggctcctaccaggagctgctggcccgggatgga
gccttcgccgaattccttcgcacgtacgccagcggcgatcaggagcaggccgagcaggat
gacgggttaacaggtgtcagcagtcccgggaaggaggtgaagcagatggagaatggcatg
ctggtgacggatgtggcggggaagcagctgcagagacagctcagcaactcctcctcctac
agcggggacgtgagccgccaccacaccagcacggctgagctgcagaaagccggtcccaag
aatgaggacgcctggaagctggtggaagcagacaaggctcaaacggggcaggtcaagctg
tccgtgtactgggactacatgaaggcgatcgggcttttcatctcctttctgagcatcttc
cttttcctgtgtaaccacgttgcctccctggtctcgaactactggctcagcctctggacc
gacgaccccatcgtcaacgggacccaggagcatactaaaatccggctgagcgtctatgga
gccctgggcatttcgcaaggtatcacggtgttcggctactccatggcggtgtccatcggg
gggatcttcgcttcccgccgcctgcacgtcgacctgctacagaacgtcctccggtccccc
atgagcttcttcgagcggacccccagtgggaacctggtgaaccgcttctctaaggagctg
gacacggtggactcgatgatcccacaagtcatcaagatgttcatgggctccctgttcaat
gtcatcggcgcctgcatcatcatcctgctggccactcccatcgcctccatcatcatccca
ccactaggcctcatctatttctttgtgcagaggttttacgtggcctcctcccggcagctg
aagcgcctcgagtcggtcagccgctccccggtgtactcccacttcaatgagaccttgctg
ggggtcagcgtcatccgtgccttcgaggagcaggagcgcttcatccgccagagtgacctg
aaggtggacgagaaccagaaggcctattaccccagcatcgtggccaacaggtggctggcc
gtgcggctggagtgtgtaggcaactgcatcgtcctgttcgctgccctgttctccgtgatc
tccaggcacagtctcagcgctggcttggtgggcctgtccgtgtcctactccctgcaggtc
accacgtacttgaactggctggttcgcatgtcatccgagatggagaccaacatcgtggcc
gtggagaggctgaaggagtattcagaaacggagaaagaggctccctggcaaatccaggag
atggctccgcccagcacctggcctcaggtgggccgagtggaattccgggactacggcctc
cgctaccgagaaaacctggacttggttctcaagcacatcaacatcaccatcaacggaggg
gaaaaggtgggcatcgtggggcggacgggagctgggaagtcgtccctgaccctgggcttg
tttcggatcaatgagtctgccgagggggagatcattatcgacgatatcaatattgccaag
atcggcctgcatgacctgcgcgtcaagatcaccatcatcccgcaggaccctgtgttgttc
tcgggttcgctccgcatgaacctggacccattcagccagtactcagacgaagaagtctgg
acgtccctggagctggctcacctgaaggacttcgtgtcaggccttcccgataagctgaac
caagagtgtgcagagggcggggagaacctgagcgtcgggcagcgccagctcgtgtgcctg
gcccgggctctgctgaggaaaaccaagatcctcgtgttggacgaggccacggcggccgta
gacctagaaaccgatgacctcattcagtctaccatccggacgcagtttgacgactgcacc
gtcctcaccatcgcgcaccgcctcaacaccatcatggactacacaagggtgatcgtcctg
gacaagggagagatccgagagtgcggccagccctccgacctcctacagcagagaggtctc
ttctacagcatggccaaagatgctggcctggtgtga |
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