KEGG   Canis lupus familiaris (dog): 403521
Entry
403521            CDS       T01007                                 
Symbol
TPO
Name
(RefSeq) thyroid peroxidase precursor
  KO
K00431  thyroid peroxidase [EC:1.11.1.8]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00350  Tyrosine metabolism
cfa01100  Metabolic pathways
cfa04918  Thyroid hormone synthesis
cfa05320  Autoimmune thyroid disease
Module
cfa_M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    403521 (TPO)
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    403521 (TPO)
 09160 Human Diseases
  09163 Immune disease
   05320 Autoimmune thyroid disease
    403521 (TPO)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.8  iodide peroxidase
     403521 (TPO)
SSDB
Motif
Pfam: An_peroxidase EGF_CA EGF_3 EGF Sushi
Other DBs
NCBI-GeneID: 403521
NCBI-ProteinID: NP_001003009
Ensembl: ENSCAFG00000003217
VGNC: 47746
UniProt: Q8HYB7
LinkDB
Position
17:760899..796526
AA seq 945 aa
MVGLVPAGSAWGGRALAVLGVTLLVALARGLLPFFLGGRDLLWGQSGEASVLGVVEESRR
VVDGAIQHTVRRDLSKRGLPSPSQLLSFSKLPEPTSRAVSRAAEIMEASVQAVRTRVYGK
LGRSWPLTDTLPEAVLDTIANASGCRPHMLPPRCPDTCLARKYRLITGACNNRDHPRWGA
SNTALARWLPPAYEDGISEPRGWNPHVLYSGFPLPPVREVTRQVIRVPNEAITEDDQYSD
LLTVWGQYIDHDVAFTPQSASGAAFGAGADCQLTCENRSPCFPIQLPPDASGPACLPFSR
SSAACGTGIQGAFFGNLSSANPRQQMNGLTSFLDASTVYGSSPALEKQLRNWTSAEGLLR
VNTRHWDAGRAHLPFMRPPAPLACVPEPGTRGTAGAPCFLAGDSRASEVPTLAALHTLWL
REHNRLASALKALNAHWSADTAYQEARKVVGALHQIITLRDYVPKVLGPEAFQQHVGPYE
GYDPTMDPTVSNVFSTAAFRFGHATVHPLVRRLDARFQEHPGLPPLRLQDAFFSPWRLLK
EGGLDPLLRGLLASPAKLPVQEQLMNEELTERLFVLGSSGSLDLASINLQRGRDHGLPGY
NAWREFCGLGRLHTRAELRSAVANATLAGRIMDLYGHPDNIDVWLGGLAEPLLPRARTGP
LFACLIGRQMKALRDGDRFWWESSGVFTDEQRRELARHSLSRVICDNTGLPSVPADAFQV
SRFPQDFEPCENIPGLNLDVWREALPQGDACGLPDSLDNGDVVLCGEAGRRVLVFSCRHG
FKLQGPEQVACSPRGGAVRAPVCRDINECEDASHPPCHGSARCRNTKGGFRCECTDPAVL
GEDGTTCVDSGRLPKASLVSIALGIVLVVGLAGLTWTLVCRWAHAGRKASLSIAELGGRG
APPPGRGAGQDGASGSLVPPLGPQGRTRAVDPTSSRSHVAQGSPA
NT seq 2838 nt   +upstreamnt  +downstreamnt
atggtcggcctggtccccgccggctccgcctggggggggagagcactcgccgtcctgggc
gtcacgctgctggtggccctcgcgcgcggcctcctccccttcttcctcggaggccgggac
ctcctgtggggacagagcggagaggccagtgtccttggcgtcgtggaggagagccggcgc
gtggtggacggcgccatccagcacaccgtgaggagagacctcagcaaaagggggctccct
tccccgtcgcagcttctgtctttttccaaactccccgagccgaccagccgagccgtctcc
cgagcggcggagatcatggaagcctccgtgcaggccgtgaggacacgggtctatgggaag
ctggggcgatcttggcctctcaccgacacgctgcccgaagccgtgctggacacgattgcc
aacgcgtccgggtgtcggccccacatgctgccccccaggtgcccggacacctgcctggcc
cgcaagtaccggctcatcacgggcgcctgcaacaacagagaccaccccaggtggggagcc
tccaacacagcgctggcgaggtggctgccgcccgcctacgaagacggcatcagtgagccc
agagggtggaacccccacgtcctgtacagcggcttcccgctgcccccggtgcgggaagtg
accagacaggttatccgggtccccaacgaggccatcacagaggacgaccagtattcggat
ctcctgacggtgtggggccagtacatcgaccacgacgtcgcgttcacaccgcagagtgcc
agcggagctgcgttcggggcgggagctgactgccagctgacgtgtgagaaccggagcccg
tgttttcccatccagctgccccccgatgcctcggggcccgcctgcttgcccttctcccgc
tcctctgccgcctgcggcaccgggatccaaggcgccttcttcggcaacctgagctcggcc
aacccgcggcagcagatgaacgggctgacgtccttcctggacgcgtccacggtgtacggc
agctccccggccttggagaagcagctgcgcaactggaccagtgccgaggggctgctccgc
gtcaacacgcgccactgggacgccggccgcgcccacctgcccttcatgcggccgcctgcg
cccttggcctgcgtgcccgagcccggcacccgcgggacggccggagcgccctgcttcctg
gcgggggacagccgtgccagcgaggtccccactctggcggcccttcacacgctgtggctg
cgcgagcacaaccgcctggcctcggcgctcaaggctctcaacgctcactggagcgcggat
accgcctaccaggaggcgcgcaaggtggtgggcgccctgcaccagatcatcaccttgcgg
gactacgtccccaaagtcctgggccccgaggccttccagcagcacgtgggcccctacgag
ggttacgaccccaccatggaccccaccgtgtccaacgtgttttccacggccgccttccgc
ttcggccacgccacggtgcacccgctggtgaggcggctggacgcccgcttccaggagcac
cccggcctccccccgctgcggctgcaggacgccttcttcagcccctggaggctcctcaag
gaaggtggtctggaccccctgctgaggggccttctcgcgagccccgccaagttgccggtg
caggagcagctgatgaatgaggagctgaccgagaggctgttcgtgctgggcagctcaggc
agcctggacctggcgtccataaacctgcagcggggccgggaccacggcctgccaggttac
aacgcgtggagggagttctgcggcctgggccggctgcacacgcgggccgagctgcgctcc
gccgtcgccaacgccaccctcgccggccggatcatggacctgtacgggcaccccgacaac
atcgacgtctggctgggcggcctggccgagcccctcctcccccgggcgcgcacgggcccg
ctgtttgcgtgcctcatcgggaggcagatgaaggctctgagggacggagaccggttctgg
tgggagagcagcggggtgttcaccgacgagcagcggcgcgagctggcgaggcactccctg
tcccgggtcatctgtgacaacacgggcctccccagcgtgcccgcggacgccttccaggtc
agcagattcccacaggacttcgagccgtgcgagaacattccgggtctgaacctggacgtg
tggagggaggcccttccgcaaggcgacgcctgcggcctccccgacagcctggacaatggg
gacgtcgtgctctgcggcgaggccgggcggcgcgtgctcgtcttctcctgccgccacggg
ttcaagctgcagggccccgagcaggtggcctgctccccccggggcggggctgtccgggcc
cccgtgtgcagagatatcaatgagtgtgaagacgcgagccaccccccctgtcacgggtcg
gcccggtgcaggaacaccaagggtggtttcaggtgtgagtgcacagaccctgcggtgctc
ggggaggacggaacgacgtgtgtagactccgggaggctcccgaaggcgtccttggtctcc
atcgcgttgggcatcgtgctggtcgttggcctggcgggtctcacctggacgctggtttgc
aggtgggcacatgcgggccgcaaagcctcactgagcatcgcggagttgggcggaagagga
gcccccccgccgggccgtggagcgggccaggacggcgcctctggcagcctggtgcccccc
ctcgggccgcagggcaggacccgggccgtggaccccacatccagtaggagccacgtggcg
cagggaagcccggcatga

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