Canis lupus familiaris (dog): 403698
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Entry
403698 CDS
T01007
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 precursor
KO
K12385
Niemann-Pick C1 protein
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
cfa04142
Lysosome
cfa04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
403698 (NPC1)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
403698 (NPC1)
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
403698 (NPC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
cfa02000
]
403698 (NPC1)
Transporters [BR:
cfa02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
403698 (NPC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
ACR_tran
Motif
Other DBs
NCBI-GeneID:
403698
NCBI-ProteinID:
NP_001003107
Ensembl:
ENSCAFG00000018183
VGNC:
43913
UniProt:
Q9GK52
LinkDB
All DBs
Position
7:64198337..64251229
Genome browser
AA seq
1276 aa
AA seq
DB search
MTARRPAVGLVLLLLCPAQVFAQSCVWYGECGIASGDKRYNCQYSGPPKPLPKDGYDLMQ
ELCPGLFFDNVSVCCDVQQLRTLKDSLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQF
LNVTETEDYVDPVTNQTKTNVKELQYYVGESFANAMYNACRDVEAPSSNDKALGLLCGKE
AEACNATNWIEYMFNKDNGQAPFTIIPIFSDLPAHGMKPMNNATKGCDEPVDEVTAPCSC
QDCSVVCGPKPQPPPAPAPWRILGLDAMYVIMWITYMAFLLMFFGAFFAVWCYRKRYFVS
EYTPIDSNIAFSVNAGDTGEASCCDALGAAFEGCLRRLFTQWGSFCIRNPGCIIFFSLAF
IAACSSGLVFSRVTTNPVDLWSAPGSQARLEKEYFDAHFGPFFRTEQLIIQAPHTSVHTY
QPYPSGSDVPFGPPLDIGILHQVLDLQTAIENITATYNNETVTLQDICVAPLSPYNKNCT
IMSVLNYFQNSHSMLDHKIGDDFYVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGP
VFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKNYENPNLT
ISFTTERSIEDELNRESNGDVFTVLISYAVMFLYISIALGHIKSCSRFLVDSKISLGIAG
ILIVLSSVMCSLGIFSYFGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQGETL
EQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSQMPAVHTFSLFAGMAVLIDFLLQITCFV
SLLGLDLKRQEKNRLDVLCCLTGSEGGTGIQASESCLFRFFKNSYSPFLLKDWMRPIVIA
VFVGILSFSIAVLNKVEIGLDQSLSMPDDSYMMDYFKSLKYLHAGPPVYFVLEEGHDYTS
LEGQNMVCGGMGCNNDSLVQQIFSAAQLDNYTHIGFAPSSWIDDYFDWVKPQSSCCRVYN
STDQFCNASVVDPACVRCRPLTQEGKRRPQGEDFMRFLPMFLSDNPNPKCGKGGHAAYGS
AVNLVGNDTSVGATYFMTYHTVLQTSADFTDAMRKAILIASNITKTMSLKGSHYRVFPYS
VFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTLVLLGCELWSAVIMCVTIAMILVNMFGVM
WLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSAKGSRVERAEEALSHMGSSVFSGI
TLTKFGGIVVLAFAKSQIFQVFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSINKAKSLA
SQERYKGTEREQLLNF
NT seq
3831 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcccgccgccccgccgtcggcctcgtcctgctgctgctctgccccgcgcaggtg
tttgcacagtcctgtgtatggtatggagagtgtggaattgcatctggagacaagaggtat
aactgccaatattcggggccaccaaaacccttgccaaaggatgggtatgacttaatgcag
gagctctgtccaggattattctttgacaatgtcagcgtgtgctgtgacgtgcagcagctc
cggactctgaaggacagcctacagcttcccctgcagttcctgtccagatgtccatcctgt
ttttataacctaatgaacctgttttgcgagctgacatgtagccctcggcaaagtcagttt
ctgaatgttacagaaactgaagattatgttgatcctgttacaaaccagacaaaaacgaac
gtaaaagaattacagtactatgtcggagagagttttgccaatgccatgtacaacgcctgc
cgggacgtggaggccccctccagtaatgacaaagccctgggactcctgtgtgggaaggag
gccgaggcctgcaatgccaccaactggatcgagtacatgttcaataaggacaacggccag
gcacctttcaccatcatacccatattttcagatcttccagcccatgggatgaagcccatg
aacaatgccaccaagggctgtgacgagcctgtggacgaggtcacggcaccgtgcagttgc
caagattgctcggtggtctgtggccccaagccccagcccccacccgctccggctccctgg
agaattttgggcctggatgccatgtatgtcatcatgtggatcacctacatggcatttttg
ctcatgttttttggagcattttttgctgtgtggtgctacagaaaacgctattttgtctct
gagtacacccccattgatagcaacatagctttctctgtaaatgccggtgacacaggggag
gcatcctgctgcgacgcacttggtgcagcatttgagggctgcctgaggcggctcttcaca
cagtggggctccttctgcatccgaaacccaggctgcatcatcttcttctccctggccttc
attgctgcctgctcttcaggcctggtgttcagccgggtcacgaccaacccagtggacctg
tggtcggcccctggcagccaggcacgcctggagaaagagtactttgatgcgcacttcggg
cctttcttccgcacggagcagctcatcatccaggccccccacaccagtgtgcacacttac
cagccgtacccctcaggatctgacgtgccctttgggcccccgcttgacatagggatcttg
caccaggttctagacttacaaaccgccattgaaaacatcaccgcaacttacaacaacgag
actgtaacacttcaagacatctgtgtggccccgctctcaccctataacaagaactgcacc
attatgagcgtgttaaattacttccagaacagccattctatgttggaccacaaaataggg
gatgacttctatgtgtatgcagattaccacacgcacttgctatattgtgtacgggctcct
gcatctctgaatgataccagtttgctccatgatccttgcctgggtacatttggtgggcca
gtgttcccgtggcttgtgttaggaggctatgatgatcaaaactacaataatgctacagcc
cttgtgattacctttcctgtcaataattactacaatgatacagagaagctccagagggcc
caggcctgggaaaaagagtttattaattttgtgaaaaactacgagaatccaaatctgacc
atttctttcactactgagcgaagtattgaggatgaactgaatcgggaaagtaacggtgat
gtcttcactgttctgatcagctatgccgtcatgtttctatacatttccatagccttgggg
cacatcaaaagctgtagcaggtttctagtggattctaaaatctcccttggcatcgctggg
atcctcattgtgttgagctcagtgatgtgctcattgggcatcttcagctactttgggatc
cccctcaccctcatcgtgatcgaagtcatcccattcctggtgttggctgttggggtagac
aacatcttcattctggtccaaacctaccagcgcgatgaacgtcttcaaggagaaactctg
gaacagcagctgggcagggtcctaggagaagtggctcctagtatgttcctgtcctccttt
tcagaggctgtagcatttttcttaggagccttgtcacagatgcccgcagtgcacactttc
tctctgtttgccgggatggcggtcctcattgacttccttcttcagattacctgttttgtg
agtctcttggggttagaccttaagcgtcaagagaaaaatcgcctggacgtcctttgctgt
ctcacaggctctgaaggtggaaccggcatccaggcctcagaaagctgcttatttcggttc
ttcaaaaactcctactccccatttctgcttaaggattggatgcggcccattgtgatagcg
gtatttgtgggcattctctcattcagtatcgcagtcctgaacaaagtggagattggattg
gatcagtctctttcaatgccagatgactcctacatgatggattatttcaagtccctcaaa
tacctgcatgcaggtccccccgtgtactttgtcctcgaggaaggacacgattacacctct
ttggaagggcagaacatggtgtgcgggggcatgggctgcaataatgactccctggtgcag
cagatcttcagcgcggctcagctggacaactatacccacataggctttgcgccctcgtcc
tggatcgacgattattttgattgggtcaagcctcagtcttcctgctgtagagtctacaac
agcacagatcagttctgcaacgcctcagtggttgaccctgcctgcgtccgctgcaggcct
ctgacccaggagggcaaacggaggcctcaaggtgaagacttcatgagattcctgcccatg
ttcctttctgataacccaaaccccaagtgcggcaaagggggacatgctgcctacggctca
gcagttaacctcgtcggcaatgacacgagtgtcggagccacttacttcatgacctaccac
accgtgcttcagacctctgctgactttactgacgccatgagaaaagccatcctcattgcc
agtaacatcaccaaaaccatgagccttaaaggaagccactaccgcgtgttcccgtacagt
gtgttctatgtcttctacgaacagtacctgaccattattgatgacacgatctttaacctt
agcgtgtcactgggagccatcttcttggtgaccttggttctcctgggctgtgaactgtgg
tctgcagtgatcatgtgtgtcaccattgccatgatcttggtcaacatgtttggcgtcatg
tggctgtggggcatcagtctgaacgcggtttccttggtcaacctggtcatgagctgtggc
atctccgtggagttctgcagccacataacgagagcgttcacagtgagtgcgaagggcagc
cgcgtggaacgggccgaagaggcgctctctcacatgggcagttctgtgttcagtggaatc
acactaacgaaatttggagggattgtggtgttggcctttgccaaatcgcagattttccag
gtattttacttcaggatgtatctggctatggtcttgctgggagccacgcacggcttgata
ttcctccctgtgttactcagctacataggcccatcaataaataaagccaaaagtttggcc
tcccaggagcgatacaaaggtacagagcgagagcagctcctgaacttctag
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