Canis lupus familiaris (dog): 403825
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Entry
403825 CDS
T01007
Symbol
PDE5A
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase
KO
K13762
cGMP-specific 3',5'-cyclic phosphodiesterase [EC:
3.1.4.35
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00230
Purine metabolism
cfa01100
Metabolic pathways
cfa04022
cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
403825 (PDE5A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
403825 (PDE5A)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
403825 (PDE5A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
HD-CE
DUF6970
Motif
Other DBs
NCBI-GeneID:
403825
NCBI-ProteinID:
NP_001003188
Ensembl:
ENSCAFG00000012472
VGNC:
44356
UniProt:
O77746
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All DBs
Position
32
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AA seq
833 aa
AA seq
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MLPFGHQRREMVNAWFAERVHTIPVCKEGIRGHAESCSCSSQQSSRADSSAPGTPTRKIS
ASEFDRPLRPIVVKDSEGTVSFLADSEKKEQMPLTPPRFDNDEGDQCSRLLELVKDISSH
LDVTALCHKIFLHIHGLISADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEASNNCIR
LEWNKGIVGHVAALGEPLNIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVA
QAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFE
EQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKLPDTLTRER
DANRINYMYAQYVKNTMEPLNIPDVSKDKRFPWTNENTGNVNQQCIRSLLCTPIKNGKKN
KVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVT
LEVLSYHASAAEEETKELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDL
NLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLE
ILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILS
GLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTA
CDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPADLMNREKKNKIPSMQVGFID
AICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQEKTLINGESSQAKRN
NT seq
2502 nt
NT seq
+upstream
nt +downstream
nt
atgttgccctttggacaccaaagaagagaaatggtcaatgcctggttcgctgagagagtc
cacaccatccctgtgtgtaaagaaggcatcagaggccacgcagaatcttgctcttgctcc
tcgcagcagagttcccgtgcagacagcagtgcgcctggcacaccaaccaggaaaatctct
gcctctgaatttgaccggcctcttagacccattgtcgtcaaagattctgagggtactgtg
agcttcctcgctgactcagaaaagaaggaacagatgcctctaacccccccaaggtttgat
aatgatgaaggggaccagtgctcgagactcttggaattagtgaaagatatttctagtcat
ttggatgtcacagccttatgtcataaaattttcttgcatattcatggacttatctccgct
gatcgctattccctgtttcttgtctgtgaggacagctccaatgacaagtttcttatcagc
cgcctgtttgatgttgcagaaggttcaacactggaagaagcttcaaataactgtatccgc
ttagaatggaacaaaggcattgtgggacatgtggcagcacttggtgagcccttgaacatc
aaagatgcttatgaggatcctcggttcaatgcagaagttgaccaaattacaggttacaag
acacagagtattctttgtatgccaattaagaatcatagggaagaggttgttggtgtagcc
caggccatcaacaagaaatcaggaaatggtgggacattcactgaaaaagatgaaaaggac
tttgctgcttatttggcattttgtggtattgttcttcataatgctcaactctatgagact
tcactgctggagaacaagagaaatcaggtgctgcttgaccttgctagcttaatttttgaa
gaacaacaatcattagaagtaattctaaagaaaatagctgccactattatctctttcatg
caggtgcagaaatgcaccattttcatagtggatgaagattgctccgattctttttctagc
gtctttcacatggaatgtgaggaattagaaaaattgccagatacgttaacaagggaacgt
gatgcaaacagaatcaattacatgtatgctcagtatgtcaaaaatactatggaaccactt
aatatcccagatgtcagtaaggacaaaagatttccctggacaaatgaaaacacaggaaat
gtaaaccagcaatgcattagaagtttgctttgtactcctataaaaaatggaaagaagaat
aaagtgataggggtttgccaacttgttaataagatggaggagaatactggcaaggttaag
cctttcaaccgaaatgatgaacagtttctggaggcttttgtcatcttttgcggcttgggg
atccagaacacacagatgtatgaagcagtggagagagccatggccaagcagatggtcaca
ctggaggttctatcctaccatgcttcagcagcagaggaggaaacaaaagagctccaatcc
ttggcggctgctgtggtaccatctgctcagacgcttaaaattactgacttcagcttcagt
gactttgagctgtctgacctagaaacagcactgtgcacaattcggatgttcactgacctc
aaccttgtgcagaacttccagatgaaacatgaggttctttgcaggtggattttaagtgtt
aagaagaattacaggaagaatgttgcctatcataattggagacacgcctttaatacagct
cagtgcatgtttgctgctttaaaggccggcaagattcagaacaagctgactgacctggag
atacttgccctgctgattgctgctctcagccacgacttggaccaccgtggtgtgaataac
tcttatatacagcgaagtgaacacccacttgctcaactctactgccattcaatcatggag
catcatcattttgaccagtgcctgatgattctcaatagtccaggcaatcagattctcagt
ggcctctccattgaagaatataagaccacgctgaaaataatcaagcaagctattttagcc
acagacctagcattgtacattaagagacgaggagaattttttgaacttataagaaaaaat
caattcaacttggaagatcctcatcaaaaagagttgtttttagcgatgctgatgacagct
tgtgacctgtctgccattacaaaaccgtggcctattcaacaacggatagcagaacttgta
gcaactgaattttttgaccaaggagacagagagagaaaagaactcaacatagagcctgct
gatctaatgaacagggagaagaaaaacaaaatcccaagtatgcaagttgggttcatagat
gccatctgcttgcaactatatgaggctctgacccacgtatcagaggactgcttccctttg
ctggatggctgcagaaagaacaggcaaaaatggcaggccctagcagaacagcaggagaaa
acgctgattaatggggaaagcagccaggccaagcggaactga
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