Canis lupus familiaris (dog): 403943
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Entry
403943 CDS
T01007
Symbol
GNAS
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha
KO
K04632
guanine nucleotide-binding protein G(s) subunit alpha
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01522
Endocrine resistance
cfa04015
Rap1 signaling pathway
cfa04020
Calcium signaling pathway
cfa04024
cAMP signaling pathway
cfa04072
Phospholipase D signaling pathway
cfa04081
Hormone signaling
cfa04082
Neuroactive ligand signaling
cfa04261
Adrenergic signaling in cardiomyocytes
cfa04270
Vascular smooth muscle contraction
cfa04540
Gap junction
cfa04611
Platelet activation
cfa04713
Circadian entrainment
cfa04714
Thermogenesis
cfa04724
Glutamatergic synapse
cfa04726
Serotonergic synapse
cfa04728
Dopaminergic synapse
cfa04730
Long-term depression
cfa04750
Inflammatory mediator regulation of TRP channels
cfa04911
Insulin secretion
cfa04912
GnRH signaling pathway
cfa04913
Ovarian steroidogenesis
cfa04915
Estrogen signaling pathway
cfa04916
Melanogenesis
cfa04918
Thyroid hormone synthesis
cfa04921
Oxytocin signaling pathway
cfa04922
Glucagon signaling pathway
cfa04923
Regulation of lipolysis in adipocytes
cfa04924
Renin secretion
cfa04925
Aldosterone synthesis and secretion
cfa04926
Relaxin signaling pathway
cfa04927
Cortisol synthesis and secretion
cfa04928
Parathyroid hormone synthesis, secretion and action
cfa04934
Cushing syndrome
cfa04935
Growth hormone synthesis, secretion and action
cfa04961
Endocrine and other factor-regulated calcium reabsorption
cfa04962
Vasopressin-regulated water reabsorption
cfa04970
Salivary secretion
cfa04971
Gastric acid secretion
cfa04972
Pancreatic secretion
cfa04976
Bile secretion
cfa05012
Parkinson disease
cfa05030
Cocaine addiction
cfa05031
Amphetamine addiction
cfa05032
Morphine addiction
cfa05034
Alcoholism
cfa05142
Chagas disease
cfa05146
Amoebiasis
cfa05163
Human cytomegalovirus infection
cfa05165
Human papillomavirus infection
cfa05200
Pathways in cancer
cfa05207
Chemical carcinogenesis - receptor activation
cfa05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
403943 (GNAS)
04020 Calcium signaling pathway
403943 (GNAS)
04072 Phospholipase D signaling pathway
403943 (GNAS)
04024 cAMP signaling pathway
403943 (GNAS)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
403943 (GNAS)
04081 Hormone signaling
403943 (GNAS)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
403943 (GNAS)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
403943 (GNAS)
09152 Endocrine system
04911 Insulin secretion
403943 (GNAS)
04922 Glucagon signaling pathway
403943 (GNAS)
04923 Regulation of lipolysis in adipocytes
403943 (GNAS)
04912 GnRH signaling pathway
403943 (GNAS)
04913 Ovarian steroidogenesis
403943 (GNAS)
04915 Estrogen signaling pathway
403943 (GNAS)
04921 Oxytocin signaling pathway
403943 (GNAS)
04926 Relaxin signaling pathway
403943 (GNAS)
04935 Growth hormone synthesis, secretion and action
403943 (GNAS)
04918 Thyroid hormone synthesis
403943 (GNAS)
04928 Parathyroid hormone synthesis, secretion and action
403943 (GNAS)
04916 Melanogenesis
403943 (GNAS)
04924 Renin secretion
403943 (GNAS)
04925 Aldosterone synthesis and secretion
403943 (GNAS)
04927 Cortisol synthesis and secretion
403943 (GNAS)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
403943 (GNAS)
04270 Vascular smooth muscle contraction
403943 (GNAS)
09154 Digestive system
04970 Salivary secretion
403943 (GNAS)
04971 Gastric acid secretion
403943 (GNAS)
04972 Pancreatic secretion
403943 (GNAS)
04976 Bile secretion
403943 (GNAS)
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
403943 (GNAS)
04961 Endocrine and other factor-regulated calcium reabsorption
403943 (GNAS)
09156 Nervous system
04724 Glutamatergic synapse
403943 (GNAS)
04728 Dopaminergic synapse
403943 (GNAS)
04726 Serotonergic synapse
403943 (GNAS)
04730 Long-term depression
403943 (GNAS)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
403943 (GNAS)
09159 Environmental adaptation
04713 Circadian entrainment
403943 (GNAS)
04714 Thermogenesis
403943 (GNAS)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
403943 (GNAS)
05207 Chemical carcinogenesis - receptor activation
403943 (GNAS)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
403943 (GNAS)
05165 Human papillomavirus infection
403943 (GNAS)
09174 Infectious disease: parasitic
05146 Amoebiasis
403943 (GNAS)
05142 Chagas disease
403943 (GNAS)
09164 Neurodegenerative disease
05012 Parkinson disease
403943 (GNAS)
09165 Substance dependence
05030 Cocaine addiction
403943 (GNAS)
05031 Amphetamine addiction
403943 (GNAS)
05032 Morphine addiction
403943 (GNAS)
05034 Alcoholism
403943 (GNAS)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
403943 (GNAS)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
403943 (GNAS)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
403943 (GNAS)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
cfa04147
]
403943 (GNAS)
04031 GTP-binding proteins [BR:
cfa04031
]
403943 (GNAS)
Exosome [BR:
cfa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
403943 (GNAS)
Exosomal proteins of other body fluids (saliva and urine)
403943 (GNAS)
Exosomal proteins of colorectal cancer cells
403943 (GNAS)
Exosomal proteins of bladder cancer cells
403943 (GNAS)
GTP-binding proteins [BR:
cfa04031
]
Heterotrimeric G-proteins
Alpha Subunits
Alpha type 2 (Gs)
403943 (GNAS)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
G-alpha
Arf
Gtr1_RagA
Roc
GTP_EFTU
TniB
AAA_29
nSTAND_NTPase5
FtsK_SpoIIIE
Motif
Other DBs
NCBI-GeneID:
403943
NCBI-ProteinID:
NP_001003263
Ensembl:
ENSCAFG00000023756
VGNC:
54650
UniProt:
P63091
LinkDB
All DBs
Position
24:42885440..42905085
Genome browser
AA seq
394 aa
AA seq
DB search
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM
RILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA
NPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD
KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK
VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY
PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
NT seq
1185 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcctcggaaacagtaagaccgaggaccagcgcaacgaggagaaggcgcagcgc
gaggccaacaaaaagatcgagaagcagctgcagaaggacaagcaggtctaccgggccacg
caccgcctgctgctgctgggtgccggagaatctggtaaaagcaccattgtgaagcagatg
aggatcctgcatgttaatgggtttaatggagagggcggcgaagaggacccgcaagctgca
aggagcaacagcgatggtgagaaggcaaccaaagttcaggacatcaaaaacaacctgaaa
gaggcgatcgaaaccatcgtggccgccatgagcaacctggtgccccccgtggagctggcc
aaccctgagaaccagttcagagtggactacattctgagcgtgatgaacgtgcctgacttt
gacttccctcctgagttctatgagcatgccaaggctctgtgggaggatgaaggagtgcgt
gcctgctatgagcgctccaacgagtaccagctgattgactgcgcccagtacttcctggac
aagattgatgtcatcaagcaggctgactacgtgcccagtgatcaggatctgcttcgctgc
cgtgtcctgacttctggaatctttgagaccaagttccaggtggacaaagtcaacttccac
atgtttgacgtgggtggccagcgcgatgaacgccgcaaatggatccaatgcttcaatgat
gtgactgccatcatcttcgtggtggccagcagcagctacaacatggtcattcgggaggac
aaccagaccaaccgcctgcaggaggctctgaacctcttcaagagcatctggaacaacaga
tggctgcgcaccatctctgtgattctgttcctcaacaagcaagacctgctcgctgagaaa
gtccttgctggaaaatcgaagattgaggactactttccagaatttgctcgctacactact
cctgaggatgctactcccgagcccggagaggacccacgcgtgacccgggccaagtacttc
atccgcgacgaatttctgagaatcagcactgctagtggagatgggcgccactactgctac
ccccacttcacttgcgctgtggacaccgagaacattcgccgtgtgttcaacgactgccgt
gacatcattcagcgcatgcaccttcgtcagtatgagctgctctaa
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