Canis lupus familiaris (dog): 442860
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Entry
442860 CDS
T01007
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01521
EGFR tyrosine kinase inhibitor resistance
cfa04010
MAPK signaling pathway
cfa04014
Ras signaling pathway
cfa04015
Rap1 signaling pathway
cfa04020
Calcium signaling pathway
cfa04072
Phospholipase D signaling pathway
cfa04144
Endocytosis
cfa04151
PI3K-Akt signaling pathway
cfa04510
Focal adhesion
cfa04540
Gap junction
cfa04630
JAK-STAT signaling pathway
cfa04810
Regulation of actin cytoskeleton
cfa05163
Human cytomegalovirus infection
cfa05200
Pathways in cancer
cfa05206
MicroRNAs in cancer
cfa05214
Glioma
cfa05215
Prostate cancer
cfa05218
Melanoma
cfa05230
Central carbon metabolism in cancer
cfa05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
442860 (PDGFRA)
04014 Ras signaling pathway
442860 (PDGFRA)
04015 Rap1 signaling pathway
442860 (PDGFRA)
04630 JAK-STAT signaling pathway
442860 (PDGFRA)
04020 Calcium signaling pathway
442860 (PDGFRA)
04072 Phospholipase D signaling pathway
442860 (PDGFRA)
04151 PI3K-Akt signaling pathway
442860 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
442860 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
442860 (PDGFRA)
04540 Gap junction
442860 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
442860 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
442860 (PDGFRA)
05206 MicroRNAs in cancer
442860 (PDGFRA)
05230 Central carbon metabolism in cancer
442860 (PDGFRA)
05231 Choline metabolism in cancer
442860 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
442860 (PDGFRA)
05218 Melanoma
442860 (PDGFRA)
05215 Prostate cancer
442860 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
442860 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
442860 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
442860 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
cfa04090
]
442860 (PDGFRA)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
442860 (PDGFRA)
Protein kinases [BR:
cfa01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
442860 (PDGFRA)
CD molecules [BR:
cfa04090
]
Proteins
442860 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Ig_6
Herpes_gE
C2-set_2
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
442860
NCBI-ProteinID:
XP_005628252
Ensembl:
ENSCAFG00000002057
VGNC:
44372
UniProt:
A0A8C0STE2
A0A8I3NAN8
A0A8P0N541
LinkDB
All DBs
Position
13:46687151..46733378
Genome browser
AA seq
1089 aa
AA seq
DB search
MGTSLLALLILGCLLAGPSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWHYP
TSEEENPNVEIRNEENNSGLFVTVLEVVNASAAHTGLYTCYYNHTQTDENEIEGRHIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLLSNDGVVHASYDSRQGFNG
TFSVGPYICEATVRGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLRVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFSQLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIERTQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCIAEGTPLPDIEWMICKDIKKCNNETSWAILANNISNIITEVHPRD
RSTVEGRVTFTRVEETIAVRCLAKNLLGAESRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADDSTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccttctggcactcctgatcttaggctgtctcctcgcagggcccagccta
atcctctgccagctttcattaccctcgatccttccaaatgaaaatgaaaaggtcgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagttggcattacccc
acgtctgaagaagagaaccccaatgtggagatcagaaatgaggagaacaacagtggcctt
tttgtgaccgtgttggaagtggtcaacgcgtcggcggcgcacacggggctgtacacttgc
tattacaaccacactcagacagacgaaaacgagatcgaaggcaggcacatctacatctat
gtgccagacccggatgtcgccttcgtacctctaggaatgacagattatttagtcatcgtg
gaggatgatgactctgccatcataccttgtcgtacaactgatcctgagactccggtcacc
ttactcagcaatgatggggtggtacatgcgtcctatgacagcagacagggctttaatggg
accttcagcgttgggccgtatatctgcgaagccactgtcaggggcaagaagttccagacc
atcccatttaatgtttatgctttaaaagcaacgtcagaacttgatctagaaatggaagct
cttaaaactgtgtataagtcaggggagacgattgtggtcacctgcgccgtctttaacaac
gaggtggtggaccttcaatggacctaccctggagaggtgaaaggcaaaggcatcaccatg
ttggaggaaataaaggtcccgtccatcaaattggtgtacactctgagggtccccgaggcc
acggtgaaagatagtggagattatgaatgtgctgcccgccaggccaccaaggaagtcaaa
gagatgaagaaagtcaccatttctgtccatgagaaagggttcattgaaatcaaacccaac
ttcagccagttggaagctgttgacctacacgaagtcaagcatttcgtggtggacgtgcag
gcctacccacctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
acagagatcaccactgacatagaaaggactcaggaaataaggtatcgaagcaaattaaag
ctgatccgtgctaaggaggaggacagtggccattacactatcgtcgttcaaaatgaggat
gacgtcaagagctatactttcgaactcttaactcaagttccctcgtctattctggacttg
gtcgatgaccaccacggctctactgggggacagaccgtgagatgcatcgctgaagggaca
cctcttcctgatattgaatggatgatttgcaaggatattaagaaatgtaataatgaaacc
tcctgggcgattttggccaacaatatctcaaacattatcacggaggtccacccccgagac
aggagtactgtggagggccgggtgaccttcaccagagtggaggagaccatcgccgttcga
tgtctggccaagaatctccttggggccgagagccgagagctgaagctggtggctcccacg
ctgcgttctgagctcacggtggcagctgcagtcctggtgctattggtgattgtgatcatc
tcacttatcgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgttggagg
gtcattgaatccatcagccctgatggacatgaatatatttacgtggacccgatgcagctg
ccttatgactcaagatgggagtttccaagagatggacttgtgcttggtcggatcctggga
tctggtgcgtttgggaaagtggttgaaggaactgcctatggattaagccgctcccagccg
gtcatgaaagtcgcagtgaagatgctgaaacccacagccagatccagtgaaaaacaagct
ctcatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaacttg
ctgggagcctgtaccaagtcaggccccatttacatcatcaccgagtactgcttctatggg
gatttggtcaactatttgcataagaatagagatagcttcctgagccgccacccggagaag
ccaaagaaagagttggacatttttggattgaaccctgctgatgacagcacacggagttac
gttattttgtcttttgaaaacaacggtgactacatggacatgaagcaagctgacaccaca
cagtatgtccccatgctggaaaggaaagaggtttctaagtactcggacatccagagatcg
ctgtatgatcgtccagcctcgtacaagaagaaatctatgttagactccgaagtcaaaaac
ctcctttcggatgataactcagaaggccttactttgttggatttgttgagcttcacctat
caagttgcgcgaggaatggagtttttggcttcgaaaaattgtgtccaccgggacctggct
gctcgaaacgtcctcctggcacaagggaaaatcgtgaagatctgcgacttcggcctggcc
agagacatcatgcacgattcaaactatgtgtctaaaggcagtacctttctccccgtgaag
tggatggctcccgagagcatcttcgacaacctctacaccacgctgagtgacgtctggtcc
tacggcatcctgctctgggagatcttttcccttggcggcacaccctaccctggcatgatg
gtggattctactttctacaataagatcaagagtggataccggatggccaagcctgaccac
gccaccagtgaagtctatgagatcatggtgaagtgctggcacagtgaaccggagaagaga
ccctccttttaccacctgagcgagatcgtggagaatctgctgcctggacaatataagaag
agttacgagaagattcacctggacttcctgaagagcgaccaccccgccgtggcgcgtatg
cgcgtggactcagacaacgcctacatcggcgtcacctacaaaaacgaggaggacaagctg
aaggactgggagggcagcctggacgagcagaggctgagcgccgacagcggctacatcatc
cccctgcccgacatcgacccggtgcccgaggaggaagacctgggcaagaggaacagacac
agctcgcagacctcagaagaaagcgctatcgagacaggttccagcagctctaccttcatc
aagagagaggacgaaaccatcgaggacatcgacatgatggacgacattggaatagactcc
tcagacctggtagaggacagcttcctgtga
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