Canis lupus familiaris (dog): 442951
Help
Entry
442951 CDS
T01007
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01521
EGFR tyrosine kinase inhibitor resistance
cfa01522
Endocrine resistance
cfa04010
MAPK signaling pathway
cfa04014
Ras signaling pathway
cfa04015
Rap1 signaling pathway
cfa04066
HIF-1 signaling pathway
cfa04068
FoxO signaling pathway
cfa04081
Hormone signaling
cfa04114
Oocyte meiosis
cfa04140
Autophagy - animal
cfa04144
Endocytosis
cfa04150
mTOR signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa04152
AMPK signaling pathway
cfa04211
Longevity regulating pathway
cfa04213
Longevity regulating pathway - multiple species
cfa04510
Focal adhesion
cfa04520
Adherens junction
cfa04550
Signaling pathways regulating pluripotency of stem cells
cfa04730
Long-term depression
cfa04913
Ovarian steroidogenesis
cfa04914
Progesterone-mediated oocyte maturation
cfa05200
Pathways in cancer
cfa05202
Transcriptional misregulation in cancer
cfa05205
Proteoglycans in cancer
cfa05214
Glioma
cfa05215
Prostate cancer
cfa05218
Melanoma
cfa05224
Breast cancer
cfa05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
442951 (IGF1R)
04014 Ras signaling pathway
442951 (IGF1R)
04015 Rap1 signaling pathway
442951 (IGF1R)
04066 HIF-1 signaling pathway
442951 (IGF1R)
04068 FoxO signaling pathway
442951 (IGF1R)
04151 PI3K-Akt signaling pathway
442951 (IGF1R)
04152 AMPK signaling pathway
442951 (IGF1R)
04150 mTOR signaling pathway
442951 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
442951 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
442951 (IGF1R)
04140 Autophagy - animal
442951 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
442951 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
442951 (IGF1R)
04520 Adherens junction
442951 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
442951 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
442951 (IGF1R)
04914 Progesterone-mediated oocyte maturation
442951 (IGF1R)
09156 Nervous system
04730 Long-term depression
442951 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
442951 (IGF1R)
04213 Longevity regulating pathway - multiple species
442951 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
442951 (IGF1R)
05202 Transcriptional misregulation in cancer
442951 (IGF1R)
05205 Proteoglycans in cancer
442951 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
442951 (IGF1R)
05214 Glioma
442951 (IGF1R)
05218 Melanoma
442951 (IGF1R)
05215 Prostate cancer
442951 (IGF1R)
05224 Breast cancer
442951 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
442951 (IGF1R)
01522 Endocrine resistance
442951 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
442951 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
cfa04090
]
442951 (IGF1R)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
442951 (IGF1R)
Protein kinases [BR:
cfa01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
442951 (IGF1R)
CD molecules [BR:
cfa04090
]
Proteins
442951 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
442951
NCBI-ProteinID:
XP_013967871
Ensembl:
ENSCAFG00000010881
VGNC:
41896
UniProt:
A0A8C0TQ22
A0A8I3MER7
LinkDB
All DBs
Position
3:44494039..44797005
Genome browser
AA seq
1344 aa
AA seq
DB search
MRWCWPWAVCGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITE
YLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRI
EKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPLCEKTTINNEYNY
RCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPT
CPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIP
CEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEV
VTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKA
GKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTWKN
RIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVE
PGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNS
SSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHNYCSKDKIPIRKYADGTIDVEEV
TENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVT
QVTNTTMSSRSRNTTVVDTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDI
HSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWESRPENSIFLKWPEPENPNGLIL
MYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFY
VPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHRRRNNSRLGNGVLYASVNPEYFSA
ADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRE
RIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEIENNPV
LAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYET
DYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLR
FVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKDEMEPGFREVSFYYSE
ENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRLSGHKAENGPGPGVLVLRASFDER
QPYAHMNGGRKNERALPLPQSSTC
NT seq
4035 nt
NT seq
+upstream
nt +downstream
nt
atgaggtggtgttggccatgggcagtctgtgggccaggcatcgacatccgcaatgactat
cagcagctgaagcgcctggagaactgtacagtgatcgagggctacctccacatcctactc
atctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtcatcaccgag
tacctgctgctgttccgtgtggccggccttgagagcctcggggatctcttccccaacctc
acagtcatccgcggctggaagctcttctacaactacgccctggtcatctttgagatgacc
aacctcaaggatattgggctttacaatctgaggaacattactcggggggccatcaggatt
gagaagaatgctgacctctgttacctctccacagtggactggtccctgatcctggatgca
gtgtccaacaactacatcgtggggaacaaaccccctaaggaatgtggggacctgtgtcca
gggacaatggaggagaagcccttgtgtgagaagactaccatcaacaatgaatacaactat
cgctgctggactacaaatcgctgccagaaaatgtgcccgagcgcttgcgggaagcgggcg
tgcacggagaacaacgagtgttgtcaccccgagtgtctgggcagctgcagcgcgccggac
aacgatacggcctgtgtggcctgcaggcattactactacgcaggcgtctgcgtgcccacc
tgcccgcccaacacctaccgctttgagggctggcgctgcgtggaccgcgacttctgcgcc
aacatccccagcgccgagagcagcgactccgaggggttcgtgatccatgacggcgagtgc
atgcaggagtgcccctctgggttcatccgcaatggcagtcagagcatgtactgcatccct
tgtgaaggtccttgtcccaaggtctgtgaggaagaaaagaaaacaaagaccattgattct
gttacctctgctcaaatgctccaaggatgtaccatcttcaagggcaatttgctcattaat
atccgccgaggcaataacattgcctcagagctggagaacttcatggggctcatcgaggtg
gtgacaggctacgtgaagatccgccattcccatgccttggtctccctgtccttcctaaaa
aaccttcgccagatcttaggagaggaacagctggaggggaactactccttctacgtcctc
gacaaccagaacttgcagcagctttgggattgggaccaccgtaacctgaccatcaaagct
gggaaaatgtattttgctttcaatcccaaattgtgcgtctccgaaatttaccgcatggaa
gaagtgacggggaccaaaggacgccagagcaaaggagacataaataccagaaacaatgga
gagcgagcctcctgtgaaagcgacgtcctgcacttcacctctacgaccacatggaagaat
cgcatcatcatcacgtggcaccgttaccggccccctgactacagggacctcatcagcttt
actgtctactacaaggaagcaccttttaaaaacgttacggagtatgatgggcaggatgcc
tgtggctccaacagctggaatatggtagatgtggacctccctcccaacaaggacgttgag
cctggcattttactgcacggactgaagccctggacgcagtatgcggtttatgtcaaggcg
gtgaccctcaccatggtggagaatgaccacatccgtggggctaagagtgaaatcttgtac
attcgcaccaatgcttcagttccttccattcccctggatgttctttctgcatcaaactcc
tcttctcagctcattgtgaagtggaacccaccctctctgcccaacggtaacctcagttac
tacatcgtgaggtggcagcggcagccccaggacagttacctttaccgccacaactactgc
tccaaagataaaatccccatcaggaagtatgctgatggcactatcgatgtcgaagaggtg
acagagaatcccaagaccgaagtatgtggtggagagaaggggccttgctgtgcctgcccc
aaaactgaggccgagaagcaggctgagaaggaggaggccgagtaccgcaaagtgttcgag
aatttcctgcacaactccatcttcgtgcccagacctgaaaggaagcgtagagatgttaca
caagtcaccaacaccaccatgtccagccgaagcaggaacaccacggtggtggacacctat
aatatcacagacccagaagagctcgagacagaataccctttctttgagagcagagtggat
aacaaggagagaactgtaatctctaacctccggccttttaccctgtaccgcattgacatc
cacagctgtaatcatgaggctgagaagctgggctgcagtgcctccaactttgtttttgca
agaaccatgcctgcagaaggagcagatgacattcctgggccagtgacctgggagtcaagg
cctgaaaactccatctttttaaagtggccagaacctgagaatcccaatggattgattcta
atgtatgaaataaaatatggatcccaaatcgaggatcagcgggaatgtgtatccagacag
gagtacaggaagtatggaggtgccaagcttaaccggctcaacccggggaactatacagcc
cggatccaggccacttctctctctgggaatgggtcgtggacggatcctgtgttcttctat
gtcccagccaaaataacgtatgaaaacttcatccatctgatcattgctctgcccgttgct
gtgctattgatagtgggagggttggttataatgctgtacgtcttccacaggagaagaaat
aacagcaggctggggaatggagtgctgtatgcttccgtgaacccagaatacttcagtgct
gccgatgtgtatgtacctgatgagtgggaggttgctcgagagaagatcaccatgagccga
gagctgggccagggctcgtttgggatggtatatgaaggagttgccaagggtgtggttaaa
gatgagcctgaaacaagggtggccattaaaacagtgaacgaggccgccagcatgcgtgaa
aggatcgaatttctcaatgaggcttcagtgatgaaggagttcaattgtcaccatgtggtg
cggttgctgggtgtggtgtcccagggccagccgacgctggtcatcatggaactgatgaca
cgaggggatctcaaaagttatctcaggtctctgaggccagaaatagagaataatccagtc
ctcgcacctccaagcctaagcaagatgatccagatggctggggagattgctgatggcatg
gcatacctcaatgccaacaagtttgtccacagagaccttgctgccaggaactgcatggtg
gccgaagatttcacagtcaaaattggagatttcggtatgacaagagacatctatgagaca
gactattaccggaaaggaggcaaggggctgctgcctgtgcgctggatgtcacctgagtct
ctcaaggatggagtcttcaccactcactctgacgtctggtcctttggggtcgttctctgg
gagatcgccacgctggctgagcagccataccagggcttgtccaacgagcaagtccttcgc
ttcgttatggagggcggccttctggacaagccggacaactgccccgacatgctgtttgag
ctgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctggagatcatc
agcagcatcaaggacgagatggagcccggcttccgggaggtctccttctactacagcgag
gagaacaagccgcccgagccggaggagctggacctggagccggagaacatggagagtgtc
cccctggacccgtcggcctcctcgtcgtccctgcctctgcctgacagactctcaggacac
aaggccgagaacggcccaggccctggcgtgctggtcctgcgagccagcttcgatgagaga
cagccttacgcgcacatgaacgggggccgcaagaacgagcgggccttgcctctgccccag
tcttcgacctgctga
DBGET
integrated database retrieval system
