KEGG   Canis lupus familiaris (dog): 475345
Entry
475345            CDS       T01007                                 
Symbol
MYLK3
Name
(RefSeq) myosin light chain kinase 3
  KO
K00907  myosin-light-chain kinase [EC:2.7.11.18]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04020  Calcium signaling pathway
cfa04022  cGMP-PKG signaling pathway
cfa04270  Vascular smooth muscle contraction
cfa04371  Apelin signaling pathway
cfa04510  Focal adhesion
cfa04517  IgSF CAM signaling
cfa04611  Platelet activation
cfa04810  Regulation of actin cytoskeleton
cfa04921  Oxytocin signaling pathway
cfa04971  Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    475345 (MYLK3)
   04020 Calcium signaling pathway
    475345 (MYLK3)
   04022 cGMP-PKG signaling pathway
    475345 (MYLK3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    475345 (MYLK3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    475345 (MYLK3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    475345 (MYLK3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    475345 (MYLK3)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    475345 (MYLK3)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    475345 (MYLK3)
  09154 Digestive system
   04971 Gastric acid secretion
    475345 (MYLK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    475345 (MYLK3)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.18  myosin-light-chain kinase
     475345 (MYLK3)
Protein kinases [BR:cfa01001]
 Serine/threonine kinases: CAMK group
  MLCK family
   475345 (MYLK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo UCP020893
Other DBs
NCBI-GeneID: 475345
NCBI-ProteinID: XP_532569
Ensembl: ENSCAFG00000003680
VGNC: 43551
LinkDB
Position
15
AA seq 850 aa
MLPPCQGAPRGRALPSCHSRRGRPRDKRRRGLADAGPRATVRAGLRTVDGNELPGPLARV
NARGRGFRDSSSSRSRLRMSGAPQEGLEPRGPPAAGKACLTTMDTKLNVLNEKVDKLLHF
QEDVTEKLQCVCQGLGHLEQGLHRLEARQVPGPAGAARTPAAAAQAGWPEVLELVRAVRQ
EAAQHGARLEALLGMLVAVDKVVAVVGAVFQNSKVVDFIMQGSVPWRKGSLADGPVENKD
RVEEKGAKPKHALSTRAVQAEIRGPWEESRRAAPPEGPAARPAPVSASGPGADVSTQAEA
LRRQEDAVPGPGPEPPGLLPLPESPGTGRGWSAASPRLGEAPRTDQGAAFGGPDLPPGLP
SPAPATQAAGEPPPRLAIHVQETDTPGELLVTRAAGLSPAPPVEAPAAARRGEQDPPGPP
LRAPATKSAGQTPRGAGGRPPPRERSDAEGEQVPGAEATGGPSGAGAARGGDAGAPDGPQ
DQGSAAGQPEPGEDRAAGDLGSRAGQGPSGAQAGAVVLDDSPAPPAPFEHRVVSVKETST
AAGYTVCQHDVLGGGRFGQVHRCTEKSTGLSLAAKIIKVKSAKDREDVKNEVNIMNQLSH
VNLIQLYDAFESKNSFTLVMEYVDGGELFDRITEEKYQLTELDVILFTKQICEGVHYLHQ
HYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFV
SFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSR
LLVKEKSCRMSATQCLKHEWLNNLPAKASKSKVRLKSQLLLQKYMAQRKWKKHFYVVTAA
NRLRKFPTCP
NT seq 2553 nt   +upstreamnt  +downstreamnt
atgctgccaccatgtcaaggggccccaaggggaagggccctgccaagctgtcactcacgc
cgcggccgacccagagataagcggaggcgagggctcgcagacgccgggccccgcgcaacc
gtgcgggctgggctgcggactgtggacggcaatgagctgccggggcccctcgcccgcgtg
aacgcccgaggccgtggcttccgcgactcatcgtcctcgcgcagccgcctcaggatgtcg
ggagccccccaggagggtttggagccccgggggccgccggcggccggcaaggcctgcctg
accaccatggacacgaagctcaacgtgctgaacgagaaggtcgacaagctcttgcacttc
caagaagacgtcacggagaaactgcagtgtgtgtgccagggcctgggccacctggagcaa
ggtctacaccggctggaggcccgtcaggtcccgggccccgctggggccgcccgcaccccc
gcagccgccgcgcaggccgggtggcccgaggtcctggagctggtgagggccgtgcggcag
gaggcggcccagcacggcgccaggctggaggccctgctcgggatgctggtggccgtggac
aaggtggtggccgtggtgggggccgtgttccagaactcgaaggtcgtggacttcatcatg
caggggagcgtgccctggaggaaaggcagcctggccgacggccccgtggagaacaaagat
cgagtagaagagaaaggagccaaaccaaagcatgcgctgagcaccagagccgtgcaggcc
gagatcagggggccctgggaagagagccggagggcggccccgccggagggcccagcggcc
aggccggcgcccgtcagcgcctcggggccaggagcggacgtgtccacgcaggcggaggcc
ctgcggcggcaggaagatgcggttcctggcccgggccctgagccccccggcctcctgccg
ctgcctgagagcccgggcaccggccggggatggtctgcagcatcccctaggctcggggag
gccccccgcacagaccagggagcagcattcggggggcctgacctgccaccagggctgccc
agcccggccccggccacgcaggccgccggagagccgcctcccaggctcgccatccacgtg
caggagacggacacgcccggggagctgcttgtgacacgcgcggccggcctcagccccgca
ccccccgtggaggccccggctgcggcccgtcggggggagcaggacccacctgggcccccc
ctgcgggcccccgccaccaagtcagcaggccagaccccgagaggagccggcgggaggccc
ccaccgcgggagcgcagcgacgccgagggggagcaggtgcccggggccgaggccaccggg
ggtccgagcggggccggtgcggccagaggaggcgacgcgggggccccggacgggccgcag
gaccagggctcggcagcaggacagcccgagcccggggaggaccgcgcagctggagacctg
ggcagccgagcaggacaggggccctctggggcccaggctggcgccgtggttctggatgac
agcccagccccaccagcccctttcgaacaccgggtggtgagcgtcaaggagacgtcgaca
gcggccggttacacagtgtgccagcatgacgtcctgggagggggccggtttggccaggtg
cacaggtgcacggagaagtccacaggcctctcgctggcagccaagatcatcaaagtgaag
agtgccaaggaccgggaggacgtgaagaatgaggtcaacatcatgaaccagctcagccat
gtgaacctgatccagctctatgacgcctttgagagcaagaacagctttaccctcgtcatg
gagtacgtggacggcggtgaactctttgaccggatcacagaggagaaataccagctgacc
gaactggatgtgatcttgttcaccaagcagatctgtgagggtgtgcattacctccatcaa
cactacatcctgcacctggacctcaagccggagaacatactgtgtgtcaatcagacagga
catcaaattaagatcattgacttcgggctggccagaaggtacaagcctcgggaaaagctg
aaggtgaacttcggcactccagagttcctggccccggaagttgtcaactatgaatttgtg
tccttcccgacggacatgtggagcgtgggggtcattacctacatgctactcagcggtttg
tccccgtttctaggggaaacagatgcagagaccatgaattttattgtgaactgtagctgg
gattttgatgctgacacctttgaagggctgtcggaggaggccaaggactttgtttcccgc
ctgctcgtcaaagagaagagctgcaggatgagtgccacacagtgcctgaaacatgagtgg
ttgaataatttgcctgccaaagcttcaaaatccaaagttcgtctcaaatcccaattacta
ctgcagaaatacatggctcagaggaaatggaagaaacatttctacgtggtgactgctgcc
aacaggctaaggaaatttccaacttgtccctaa

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