KEGG   Canis lupus familiaris (dog): 476078
Entry
476078            CDS       T01007                                 
Symbol
MGST2
Name
(RefSeq) microsomal glutathione S-transferase 2 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00480  Glutathione metabolism
cfa00980  Metabolism of xenobiotics by cytochrome P450
cfa00982  Drug metabolism - cytochrome P450
cfa00983  Drug metabolism - other enzymes
cfa01100  Metabolic pathways
cfa01524  Platinum drug resistance
cfa05200  Pathways in cancer
cfa05204  Chemical carcinogenesis - DNA adducts
cfa05207  Chemical carcinogenesis - receptor activation
cfa05208  Chemical carcinogenesis - reactive oxygen species
cfa05225  Hepatocellular carcinoma
cfa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    476078 (MGST2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    476078 (MGST2)
   00982 Drug metabolism - cytochrome P450
    476078 (MGST2)
   00983 Drug metabolism - other enzymes
    476078 (MGST2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    476078 (MGST2)
   05204 Chemical carcinogenesis - DNA adducts
    476078 (MGST2)
   05207 Chemical carcinogenesis - receptor activation
    476078 (MGST2)
   05208 Chemical carcinogenesis - reactive oxygen species
    476078 (MGST2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    476078 (MGST2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    476078 (MGST2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    476078 (MGST2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:cfa02000]
    476078 (MGST2)
Enzymes [BR:cfa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     476078 (MGST2)
Transporters [BR:cfa02000]
 Other transporters
  Pores ion channels [TC:1]
   476078 (MGST2)
SSDB
Motif
Pfam: MAPEG PhrC_PhrF
Other DBs
NCBI-GeneID: 476078
NCBI-ProteinID: XP_038310526
VGNC: 54328
LinkDB
Position
19:complement(3314243..3335238)
AA seq 146 aa
MPARSVLLAAASVLSACQQSYFALHVGKARLKYKVTPPAVSGSPEFERMFRAQQNCVEFY
PIFLVTLWMAGWYFNQVFATCLGLVYIYARHQYFWGYSEAAKKRITGFRLSLGCLALLTV
LGALGIANSFLDEYLDLNVIKKLRHF
NT seq 441 nt   +upstreamnt  +downstreamnt
atgccggcgcgctcggtcctgctggctgccgcctcggtcctgtccgcctgccaacaaagt
tattttgctttacatgtaggaaaggcaagattaaaatacaaagtaacgcccccggccgtt
tctgggtcaccagagtttgagaggatgttccgtgcacaacaaaactgtgtggagttttac
cccatatttctggttacattgtggatggctggatggtatttcaatcaagtttttgctact
tgtctcggtctggtgtacatatacgcccgtcaccagtatttctggggatattcagaagca
gctaagaaaaggatcacgggtttccggctgagtctggggtgtctggccttgctgacagtc
ctgggagccttggggattgcaaacagctttctggatgaatacctggacctcaatgtcatc
aagaaactgagacacttctaa

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