Canis lupus familiaris (dog): 477044
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Entry
477044 CDS
T01007
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X4
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
477044 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
cfa03032
]
477044 (TOP2B)
03036 Chromosome and associated proteins [BR:
cfa03036
]
477044 (TOP2B)
Enzymes [BR:
cfa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
477044 (TOP2B)
DNA replication proteins [BR:
cfa03032
]
Eukaryotic type
DNA Topoisomerases
477044 (TOP2B)
Chromosome and associated proteins [BR:
cfa03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
477044 (TOP2B)
Centrosome formation proteins
Centriole proteins
477044 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
477044
NCBI-ProteinID:
XP_022264275
Ensembl:
ENSCAFG00000005702
VGNC:
49632
UniProt:
A0A8P0SB75
A0A8I3Q0P9
LinkDB
All DBs
Position
23:18145151..18204187
Genome browser
AA seq
1609 aa
AA seq
DB search
MSYLSTSRNSRRRENNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYIGS
VEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPES
NIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIF
STKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDK
DIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELA
NERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKP
FQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILN
WVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGL
GVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRY
GKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIP
EFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAF
SKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNER
SIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQ
NFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAVDDNLLKFLYDDN
QRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYK
NFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPAL
ISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYE
TVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDL
IQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPDFNYILNMSLWSL
TKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMAGK
AIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKKKKGDLDTTAVKVEF
DEEFSGTPVEGTGEEALIPSAPVNKGPKPKREKKEPGTRVRKTPTSSGKSSAKKVKKRNP
WSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDNNDLEEL
KVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQDFGNLFSFPSYSQ
KSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTIAAKKGKPSSDTAAKPKRTPKQKK
VETINSDSDSEFGIPKKTTPPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTS
FDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4830 nt
NT seq
+upstream
nt +downstream
nt
atgtcttatttgtcaacatcaaggaattccagaaggagagagaacaatgctgccaaaaaa
gaagaatcagaaactgcaaacaaaaatgattcttcaaagaagttgtctgtggagagagta
tatcagaaaaagacacaacttgaacatattctccttcgtcctgatacatacattgggtca
gtggaaccattgacacagctaatgtgggtatatgatgaagatgtaggaatgaattgcaga
gaggttacctttgtgccaggtttatacaagatctttgatgaaattttggttaatgcagct
gacaataaacagagggataagaatatgacctgtattaaagtttctattgatcctgaatct
aacattataagcatttggaataatgggaaaggcattccagtagtagaacacaaagtagag
aaagtttatgttcctgcattaatttttggacagcttttaacatccagtaactatgatgat
gatgagaaaaaagtaacaggtggtcgtaatggttatggtgcaaaactttgtaatattttc
agtacgaagtttacagtagaaactgcttgcaaagaatacaaacatagttttaagcagaca
tggatgaataacatgatgaagacttctgaagccaaaattaaacattttgatggtgaagat
tacacatgcataacattccaaccagatctgtctaaatttaagatggaaaagcttgacaag
gatattgtggccctcatgaccagaagagcttatgatttggctggttcatgcaagggggtc
aaggtcatgtttaatggaaagaaattgcctgtgaatggatttcgtagttatgtagatctt
tatgtgaaagacaagttggatgaaactggagtggccctgaaagttattcatgaacttgca
aatgaaagatgggatgtttgtctcacattgagtgaaaagggattccagcaaatcagcttt
gtaaatagtattgcaacaacaaaaggtggacggcatgtggattatgtagtagatcaagtt
gttggtaaactgattgaagtagttaagaaaaagaacaaagctggtgtatcagtaaaacca
tttcaagtgaaaaaccacatatgggtttttattaattgccttattgaaaatccaactttt
gattctcagactaaggaaaacatgactctgcaacccaaaagttttgggtctaaatgccaa
ctatcagaaaaattttttaaagcagcttctaactgtggcattgtagaaagtattctgaat
tgggtgaaatttaaggctcagactcagctgaacaagaagtgttcatcagtaaagtatagt
aaaatcaaaggtattcccaaactggatgatgctaatgatgctggtggcaaacattccctg
gagtgtacactgatactaacagagggagactctgccaaatcgctggctgtgtctggatta
ggtgtgattgggcgagacagatacggagtctttccacttaggggaaagattcttaatgta
cgggaagcttctcataaacagatcatggaaaatgcagaaataaacaatattatcaaaata
gttggtctacaatacaagaaaagttatgatgatgcagaatctttgaaaactttacgctat
gggaagattatgattatgactgatcaggatcaagatggttctcatataaaaggcctactt
attaatttcatccatcacaattggccatcacttttgaagcatggttttcttgaagagttc
attactcctattgtaaaggctagcaaaaataagcaggaactttccttctatagtattcct
gaatttgatgagtggaaaaaacatatagaaaaccagaaagcctggaaaataaaatactac
aaagggttgggtaccagtacagctaaagaagcaaaagaatattttgctgatatggaaaga
caccgcatcttgtttagatatgctggtcctgaagatgatgctgccattaccttggcattc
agtaaaaagaagattgatgacagaaaagaatggttaacaaattttatggaagaccggaga
cagcgtaggttacatggcttaccagagcaatttttgtatggtacagcaacaaagcatttg
acttacaatgatttcatcaataaggaactgattctcttctcaaactcagacaatgaaaga
tctataccatctcttgttgatggttttaaaccaggacaacgaaaagttttatttacctgt
ttcaagaggaatgataaacgtgaagtaaaagttgctcagttggctggatctgttgcagag
atgtctgcttatcatcatggagaacaagcattgatgatgactattgtgaatttggctcag
aactttgtgggaagtaacaacattaatttgcttcagcctattggtcagtttggaactcgg
cttcatggtggcaaagatgctgcaagccctcgttatattttcacaatgttaagctcttta
tcaagactcctttttcctgctgtggatgacaacctgcttaaattcctttatgatgataat
caacgtgtagagcctgagtggtatattcctataattcccatggttttaataaatggtgcg
gagggcattggtactggatgggcttgtaagctacccaactatgatgctagagaaattgtg
aacaatgtcagaagaatgctagatggcttggatcctcatcccatgcttcctaactacaaa
aactttaaaggaacgatccaagagcttggtcaaaaccagtatgctgtcagtggtgaaata
tttgtggtggatagaaacacagtagagattacagagcttccagttagaacttggactcag
gtatacaaagaacaggttttagaacctatgctaaatggaacagataaaacaccggcatta
atttctgattataaagagtatcatactgatacaactgtgaaatttgtggtgaaaatgact
gaagaaaagctagcacaagcagaagctgctggattgcacaaagtttttaaacttcaaact
actcttacttgtaattccatggtactatttgatcatatgggatgtctcaagaagtatgaa
actgtgcaagacattttgaaagaattctttgatttacgattaagttattatggtttacgt
aaggaatggcttgtaggaatgttgggagcagagtctacaaagcttaacaatcaagcccgt
ttcattttagagaagatacaaggaaaaattactatagagaataggtcaaagaaagatttg
attcaaatgttagtccagagaggttatgaatctgacccagtgaaagcctggaaagaagca
caagaaaaggcagcagaagaggaagaaacacaaaaccagcatgatgatagttcctctgat
tcaggaactccttcaggccccgattttaattatattttaaatatgtctctgtggtctctt
actaaagaaaaagttgaagaactgattaaacagagagatgcaaaagggcgagaggtcaat
gatcttaaaagaaagtctccttcagatctttggaaagaagacttagcagcatttgtcgaa
gaactggataaagtggaagcgcaagaacgagaggatattttggccggaatggctggaaaa
gcaataaaaggtaaagttggcaaacctaaggtgaagaaacttcaattggaagagacaatg
ccctcaccctatgggagaagaatagttcctgaaattactgctatgaaggcagatgccagc
aaaaagttgctgaagaagaaaaagggcgaccttgatactacagcagtaaaagtagaattt
gatgaagaattcagtggaacaccagtagagggtactggagaagaggcattgatcccgtca
gctcctgtaaataaaggtcccaaacccaaaagggagaaaaaggagcctggtaccagggtg
agaaaaacacctacatcatctggtaaatccagtgcaaagaaagtgaagaaacggaatcct
tggtcagatgatgaatccaagtcagaaagtgatttggaagaaacagaacctgtggttatt
ccaagagattctttgcttaggagagcagctgctgaaagacctaagtacacatttgatttc
tcagaagaagaggatgatgatgctgatgatgatgatgacaataatgatttagaggaattg
aaagttaaagcatctcccataacaaatgatggggaagatgaattcgttccttcagatggc
ctagataaagatgaatatacattttcaccaggcaaatcaaaagctactccagaaaaatct
tcacatgacaaaaaaagtcaagattttgggaatctcttctcatttccttcatactctcag
aagtcagaagatgattcagctaaatttgatagcaatgaagaagattctgcctctgttttt
tcaccgtcatttggtctgaaacaaacagataaggttccaagtaaaacaatagctgctaaa
aagggaaagccgtcttcagatacagctgctaagcctaagagaacccctaaacagaagaaa
gtagaaactataaactctgactcagattcagaatttggcattccaaagaagactacaccc
ccaaaaggtaaaggccgaggggcaaagaaaaggaaagcatctggctctgaaaatgaaggt
gattataaccctggcaggaaaacatccaaaacaacaagcaagaaaccgaagaaaacatct
tttgatcaggattcagatgtggacatcttcccatcagacttcacttctgaaccaccttct
ctgccacggaccggtagggctaggaaagaagtaaaatattttgcagagtctgatgaagaa
gaagatgttgattttgcaatgtttaattaa
DBGET
integrated database retrieval system
