Canis lupus familiaris (dog): 477692
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Entry
477692 CDS
T01007
Symbol
LRP6
Name
(RefSeq) low-density lipoprotein receptor-related protein 6
KO
K03068
low density lipoprotein receptor-related protein 5/6
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04150
mTOR signaling pathway
cfa04310
Wnt signaling pathway
cfa04928
Parathyroid hormone synthesis, secretion and action
cfa05010
Alzheimer disease
cfa05022
Pathways of neurodegeneration - multiple diseases
cfa05200
Pathways in cancer
cfa05224
Breast cancer
cfa05225
Hepatocellular carcinoma
cfa05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
477692 (LRP6)
04150 mTOR signaling pathway
477692 (LRP6)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
477692 (LRP6)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
477692 (LRP6)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
477692 (LRP6)
05226 Gastric cancer
477692 (LRP6)
05224 Breast cancer
477692 (LRP6)
09164 Neurodegenerative disease
05010 Alzheimer disease
477692 (LRP6)
05022 Pathways of neurodegeneration - multiple diseases
477692 (LRP6)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cfa04131
]
477692 (LRP6)
Membrane trafficking [BR:
cfa04131
]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
477692 (LRP6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ldl_recept_b
FXa_inhibition
Ldl_recept_a
Vgb_lyase
DUF5050
SGL
EGF_LRP2
cEGF
EGF
Motif
Other DBs
NCBI-GeneID:
477692
NCBI-ProteinID:
XP_013964029
Ensembl:
ENSCAFG00000013324
VGNC:
42778
UniProt:
A0A8C0NS55
A0A8I3Q1I5
LinkDB
All DBs
Position
27:complement(12280309..12442407)
Genome browser
AA seq
1613 aa
AA seq
DB search
MGAVLRSLLACSFCALLRAAPLLLYANRRDLRLVDATNGKENATIVVGGLEDAAAVDFVF
GHGLIYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIE
VSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFVIINTE
IYWPNGLTLDYEEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWT
DWNTHSILACNKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMS
PVKPFYQCACPTGVKLLENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIR
HAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWT
DTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWGEIPKIERAALDGSD
RVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTL
LGDYVYWTDWQRRSIERVHKRSAEREIIIDQLPDLMGLKATNVHRIIGSNPCAEENGGCS
HLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISLETNNNNVAIPLTG
VKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLY
WADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDG
SERTTLVPNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQ
YQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHC
SHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILP
IHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSVPNQNLEIQPYDLS
IDIYSRYIYWTCEATNVINVTRLDGRSIGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERS
PKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLE
DSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQ
EYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTGE
IDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEK
NCEVLCLIDQFRCSNGQCIGKHKKCDHNVDCSDKSDELDCYPTEEPAPQATNTVGSVIGV
IVTIFVSGTIYFICQRMLCPRMKGDGETMTNDYVVHGPASVPLGYVPHPSSLSGSLPGMS
RGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTM
EFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCDSDYAPSRRMTSVATAKGYTSDL
NYDSEPVPPPPTPRSQYLSAEENYESCPPSPYTERSYSHHLYPPPPSPCTDSS
NT seq
4842 nt
NT seq
+upstream
nt +downstream
nt
atgggggccgtcctgaggagcctcctggcctgcagtttctgtgcgctcctgagagcggcc
cctttgttgctttatgcaaacagacgggacttgcgattggttgatgctacaaatggcaaa
gagaatgctacaattgtagttggaggcttggaggatgcagctgcggtggactttgtgttt
ggtcatggcttgatatactggagtgatgtcagcgaagaagccattaaacgaacagaattt
aacaaaactgagagtgtacagaatgttgttgtctctggattattgtcccctgatgggctg
gcatgtgattggcttggagaaaaattatactggacagattctgaaacaaatcggattgaa
gtttctaatttagatggatctttacgaaaagttttattttggcaagagttggatcaaccc
agagctattgccttagatccttcaagtgggttcatgtactggacagactggggagaagta
ccaaagatagaacgtgctggaatggatggttcaagtcgcttcgttataataaacactgaa
atttactggccaaatggactgactttggattatgaggaacagaagctttactgggcagat
gcaaaactcaatttcatccacaaatcaaatctggatggaacaaatcggcaggcagtggtt
aaaggttctcttccacatccttttgccttgacattatttgaggacacattgtactggact
gactggaacacacactccattttggcttgcaacaagtacactggcgagggtctgcgtgaa
atccattctaacatcttctctcccatggatatacatgccttcagccaacagagacagcca
aatgctacaaatccatgtggaattgataatggtggttgttcccacttatgtttgatgtct
ccagtcaagcctttttatcagtgtgcttgcccaactggggtcaaactcctggagaatgga
aaaacctgcaaagatggtgccactgaattactgcttttagcacgaaggacagacttgaga
cgtatttctttggatacgccagattttacggacattgttttacagttagaagacatccgt
catgccattgccatagattatgatcctgtggaaggctatatctactggactgatgatgaa
gtgagggccatacgccgctcattcatagatggatctggcagtcagtttgtggtcaccgct
caaattgcacatcctgatggcattgctgttgactgggttgcccgaaatctttattggaca
gatactggcactgatcggatagaagtgacaaggctcaatggtaccatgaggaagatcttg
atttcagaggacttagaggaaccccgggctattgtgttagatcccatggttgggtacatg
tattggactgactggggagaaatcccgaaaattgagcgagcagctctggatggttctgac
cgagtagtgttggttaatacttctcttggttggccaaatggtttagccttggattatgat
gaaggcaaaatatactggggagatgccaaaacagacaaaattgaggttatgaatactgat
ggcactgggagacgagtactagtggaagataaaattcctcacatatttgggtttactttg
ttgggtgactatgtttactggactgactggcagaggcgtagcatcgaaagagtacacaaa
cgaagtgcagaaagggaaatcatcatagatcagcttcctgacctcatgggcctaaaggcc
acaaatgttcatcgaatcattggttccaacccctgtgctgaggaaaatgggggatgtagc
catctttgcctctataggcctcagggcctccgctgtgcctgccccattggctttgaactc
atcagtgacatgaaaacctgcattgtcccagaggctttccttttgttttcacggagagca
gatattaggcgaatttctttggaaactaacaataataatgtggccattcctctcactggt
gtcaaagaagcttctgctttggattttgatgtaactgacaaccgcatttactggaccgat
atatcactcaagaccatcagcagagcctttatgaatggcagtgcactggaacatgtggta
gaattcggcttggattacccagaaggcatggcagtagactggctcggaaagaacttgtac
tgggctgacacaggaacgaatcgaattgaggtgtcaaagctagacgggcagcaccgacag
gttttggtgtggaaagacctagatagtcccagagctcttgcactggaccctgctgaagga
tttatgtattggactgaatggggtggaaaacctaagatagacagagctgccatggatgga
agtgaacgtactacattagttccaaatgtggggcgggcaaatggcctaactattgattat
gctaaaaggaggctttattggacagacctggacactaacttaatagaatcttcgaatatg
cttggactcaaccgtgaagttatagcagatgatttgcctcatccttttggcttaactcag
taccaagattacatctactggaccgattggagccgacgcagcattgaacgtgccaacaaa
accagtggccaaaaccgcaccatcattcagggccatttggattatgtgatggacatcctc
gtctttcactcctctcggcaggcgggctggaatgagtgtgcttccagcaatgggcactgc
tcccacctctgcttggctgttccagtaggaggttttgtttgtggatgtcctgcccactac
tctcttaatgccgacaacaggacttgtagtgctccaactactttcctgctcttcagtcaa
aagagtgccatcaaccgcatggtgattgatgagcagcagagccctgacatcatccttcct
atccacagtcttcggaatgtccgggccattgattatgacccactggacaagcaactctat
tggattgactcacgacaaaacatgatccgaaaagcacaagaagatggcagccagggcttt
actgtggttgtgagctcagttccaaatcagaacctagaaatacaaccctatgacctcagc
attgatatttatagccgctacatttactggacttgtgaggccaccaatgtcattaatgta
acaagattagatgggagatcaattggagtggtactgaaaggcgagcaagacagacctcga
gccattgtggtaaacccggagaaggggtatatgtattttaccaatcttcaggaaaggtct
cccaaaattgaacgggctgctttggatggaacagaacgggaggtcctctttttcagtggc
ttaagtaaaccaattgctttagcccttgatagcagattgggcaagcttttttgggcagat
tcagatctccggcgaattgaaagcagtgatctctcaggtgccaaccgaatagtattagaa
gactccaatatcttgcagcctgtgggactgactgtgtttgaaaactggctatattggatt
gataagcagcagcaaatgattgaaaaaattgacatgacaggccgagagggtagaaccaaa
gtccaggctcgaattgcccagcttagtgacattcatgctgtgaaagagctgaaccttcag
gaatatagacagcacccttgcgctcaggataatggtggctgttcacatatttgtcttgtg
aaaggagatggtactacaaggtgctcttgccccatgcacttggttctgcttcaagatgag
ctgtcctgtggagaacccccaacatgttctcctcagcagtttacttgtttcacgggagaa
attgactgtatccctgtggcttggcggtgcgatgggtttactgaatgtgaagaccacagt
gatgagctcaattgccctgtttgctcagagtcccaattccagtgtgccagtgggcagtgt
attgatggtgccctccgatgcaatggagatgcaaactgccaggataaatcagatgagaag
aactgtgaagtgctgtgtttaattgatcagttccgctgttccaacggtcagtgcattgga
aaacataagaaatgtgatcataatgtggattgcagtgacaaatcagatgaactggattgt
tatccaactgaggaaccagctccacaggccaccaatacagttggttcagttattggagta
attgtcaccatttttgtgtctggaacaatatactttatctgccagagaatgttgtgtcca
cgtatgaagggagatggggaaaccatgactaacgattatgtagttcatggaccagcttct
gtgccccttggttatgtgccacatccaagttctttgtcaggatctcttccaggaatgtct
cgaggtaaatcaatgatcagctccctaagtatcatggggggaagcagtggacccccttat
gaccgagctcatgtcacaggagcatcatcaagtagttcttcaagcaccaaaggcacttac
ttccctgcaattttgaaccctccgccatccccagccacagagcgatcgcattatactatg
gaatttggttattcttcaaatagtccttccactcataggtcctacagctacaggccatat
agttaccggcactttgcacccccgaccacaccctgcagcacagacgtttgtgacagtgac
tatgctcccagccgaagaatgacctcagtggcaacagccaagggctacactagtgacttg
aactatgactcagagcctgtgcccccacctcccacaccccgaagccaatacctgtcagca
gaagagaactatgaaagctgtccaccttctccatacacagagaggagctactctcatcac
ctctacccaccgccgccctctccctgtacagactcctcctga
DBGET
integrated database retrieval system
