Canis lupus familiaris (dog): 478003 Help Entry 478003            CDS       T01007                                  Symbol OPTN Name (RefSeq) optineurin isoform X1   KO K19946   optineurin Organism cfa  Canis lupus familiaris (dog) Pathway cfa04137   Mitophagy - animal cfa04140   Autophagy - animal cfa05014   Amyotrophic lateral sclerosis cfa05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:cfa00001]  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     478003 (OPTN)    04137 Mitophagy - animal     478003 (OPTN)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     478003 (OPTN)    05022 Pathways of neurodegeneration - multiple diseases     478003 (OPTN)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:cfa04131]     478003 (OPTN) Membrane trafficking [BR:cfa04131]  Exocytosis   Small GTPases and associated proteins    Rab associated proteins     478003 (OPTN)  Protein recycling   Rab GTPases and associated proteins    Other Rab GTPase associated proteins     478003 (OPTN)  Autophagy   Mitophagy    PINK1-Parkin associated proteins     478003 (OPTN)   Xenophagy    Cargo receptors     478003 (OPTN) SSDB OrthologParalogGFIT Motif Pfam:  CC2-LZ NEMO zf_C2H2_10 DUF8106 EDR4-like_1st Zn_ribbon_CLPX_N AAA_13 Motif Other DBs NCBI-GeneID:  478003 NCBI-ProteinID:  XP_038313029 Ensembl:  ENSCAFG00000004769 VGNC:  44136 UniProt:  A0A8I3MA34 LinkDB All DBs Position 2 Genome browser AA seq 574 aa AA seqDB search MSHQPLSCLTAKGDSSNETTGNGPPNLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKL NNQAMKGRFEELSAWTEKQKEERLYFEVQSKEAKERLMALSHENEKLKEELEKLKGKTEM SLKDPAGDLKAPKAEADQEVEQLKTQVAYLQAEKADLLGIVSELQLKLNSGGPSEDSFVE IRIAEGEADVAVREIRTSPGPTRTDSVDTNKSTEGARNYLEFEKLTVSQLLLCLREENQK VERLKTALKEAKERVLYFEKKASGGSEIETQTEESTEKEKEEEKGPETVGSEVETLNRQV TTLFKELQEAHTKLSEAELMKKRLQEKCQTLERKNSATPSELNEKQELVYNNKKLELQVE SMRSEIKMEQAKTEEEKSKLATLQLTHNKLLQEYNNSLKTIEELKRKESEKVDKVILQEL SEKLELAEKALASKQLQMDEMKQTITKQEEDLETMTVLRAQMEVYCSDFHAERAAREKIH EEKEQLALQLAILLKENNAFEDGGSRQSLMEMQSRHGARTSDPDQQAYLVQRGTEDRSWQ RQQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII NT seq 1725 nt NT seq  +upstreamnt  +downstreamnt atgtcccaccaaccacttagctgcctgactgcaaagggggacagctccaatgaaaccaca ggaaatggaccccccaatctggctcacccaaacctggacaccttcactccagaggagctg ctgcagcagatgaaggagctcctaactgagaaccatcagctcaaagaagccatgaaacta aataatcaggcgatgaaagggcgatttgaggagctttcagcctggacagagaagcagaag gaagaacgcctttattttgaggtacagagcaaagaagccaaagaacgcctcatggctttg agtcatgagaatgaaaaattgaaggaagaacttgaaaaactaaaagggaaaacagagatg tctcttaaggacccggctggggacctcaaagcccccaaggcagaagcagaccaggaagtg gaacagctgaagacccaggtggcctatcttcaagctgaaaaggccgatctgctggggatt gtgtctgaactccagctcaagctgaactcaggcggcccctcggaagactcctttgtggaa atcaggatagctgaaggagaagcagatgtggcagtgagagaaatcaggacaagtcctggt cccacgagaactgattccgttgacacgaacaaatctacagaaggtgcaaggaattatttg gaatttgagaaattaactgtgagccagctcctgctttgtctaagggaggaaaaccagaag gtggagaggcttaaaactgcactcaaggaagccaaagaaagagttttatattttgaaaag aaagccagtggtggttctgagattgagacccagacagaggagagcacagaaaaagagaaa gaagaggagaaaggcccagaaactgttggcagtgaagtggagacattgaaccgtcaggtg acaaccctatttaaggagcttcaagaggcacatacaaaactcagtgaggctgagttaatg aagaagagacttcaagagaaatgtcagacccttgaaaggaaaaattctgcaaccccatca gagctgaatgaaaagcaagagcttgtttataacaacaaaaagttggagctacaagtggaa agcatgcgatcagaaatcaaaatggagcaagctaaaaccgaagaggagaagtccaagtta gccactctccagttgacacataacaagcttcttcaagaatacaataattcattgaaaaca atcgaggaactgaaaaggaaagagtcagaaaaagtggataaggtgattctgcaagaacta agtgaaaaactggaactggcagagaaggccctggcttccaagcagcttcagatggatgag atgaagcagaccatcaccaagcaggaggaggacctggaaaccatgaccgttcttagggct cagatggaggtttactgttctgactttcatgctgaaagagcagcaagagagaagatacat gaagaaaaggaacagctggcgctgcagctggcaatcctgctgaaagagaataatgctttt gaagatggaggcagtaggcagtctttgatggagatgcagagccgtcatggggcaagaaca agtgaccctgaccagcaggcctacctcgtccagagaggaactgaggatagaagctggcag cggcagcagcagcgtaatattccgattcattcctgccccaaatgtggagaagttctaccc gatatagacacactccagatccacgttatggactgcatcatttaa

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