Canis lupus familiaris (dog): 478257
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Entry
478257 CDS
T01007
Symbol
EIF2AK4
Name
(RefSeq) eIF-2-alpha kinase GCN2 isoform X12
KO
K16196
eukaryotic translation initiation factor 2-alpha kinase 4 [EC:
2.7.11.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04140
Autophagy - animal
cfa05160
Hepatitis C
cfa05162
Measles
cfa05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
478257 (EIF2AK4)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
478257 (EIF2AK4)
05162 Measles
478257 (EIF2AK4)
05168 Herpes simplex virus 1 infection
478257 (EIF2AK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
478257 (EIF2AK4)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
478257 (EIF2AK4)
Protein kinases [BR:
cfa01001
]
Serine/threonine kinases: Other
PEK family [OT]
478257 (EIF2AK4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RWD
HGTP_anticodon2
tRNA-synt_His
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
478257
NCBI-ProteinID:
XP_005638286
Ensembl:
ENSCAFG00000008775
VGNC:
40259
UniProt:
A0A8P0NU27
LinkDB
All DBs
Position
30:7199521..7302773
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AA seq
1600 aa
AA seq
DB search
MAGGRGAPGRGRDEPPESYPQRQEHELQALEAIYGADFQDLRPDARKSVNEPPEINLVLY
PQGLTGEEVYVQVDLRVKCPPTYPDVVPEIELKNAKGLSNESVHLLKSHLEKVAKKHCGE
QREILHEIQRRKEEIKEERKRKEMAKQERLEIASLSNQDQNSRKDPGGHRISAILHGGSP
DFVGNGKHRTNSSGRSRRERQYSLCSSEDSSGSCEVLYFSMGSPDQLMVYKGRCIGSDEQ
LGKLVYNALETATGNFVSLHEWVLRWQKKMGPFLTSQEKEKIDKCKKQIQGAETEFNSLV
KLSHPNVVRYFAMNLKEQDDSIMVDILLEHINGVSLSAHLSHSGPIPVYQLRKYTAQLLS
GLDYLHSNDVVHKVLNASNVLVDAEGNVKITDYSISKRLADICKEDVFEQSRVSFSDSAL
PYKTGKKGDVWCLGLLLLFLSQGQECGEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQ
QLLKHSFINPQPKMSLLEQSPDDSGGQDYVETVIPSKQLPSAAFFSETQRQFSRYFIEFE
ELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASRHFRRIKGEVTLLSRLHHENIVRY
YNAWIERYERPVGPGMLPQDSDSWPQAPDGRALSQPSPGNDSPDGDGAGSVEAAAPPPIL
SSVEWSTSGERSASARFPSARPGSSSEEDDDDDEHEGVFSQPFLPASDSDSDVIFEDENS
KSQNQEEDCNGKNSCHESEPSTTTEAVHYLYIQMEYCEKSTLRDTIDQGLYQDTIRLWRL
FREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFTADGKQDDTADH
LIKSDPSGHLTGMVGTALYVSPEVQGSSRPTYNQKVDLFSLGIIFFEMSYHPMVTASERI
FVLNQLRDPTSPKFPEDFDDGEHTKQKSVISWLLNHDPAKRPTATELLKSELLPPPQMEE
SELHEVLHHTLANVDGKAYRTMMAQIFSQRVSPAIDYTYDSNMPKGFSIRTSKIQQHVCD
TIVRIFKKHGAVQLCTPLLLPQNRQIYEHNEAALFMDHSGMLVMLPFDLRVPFARYVARN
NILNLKRYCIERVFRPRKLDRFHPKELLECAFDIVTSTTNSSLPTAEVIYTICEIIQEFP
ALQERNYSIYLNHTMLLKAIFLHCGIPEDKLSQVYVILYDAVTEKLTRREVEAKFCNLSL
SSNSLCRLYKFIEQKGDLQDLTPAINSLIKQKTGVAQLVKYGLKDLEEIIGLLKKLGIKL
QVLINLGLVYKVQQHNGVIFQFVAVIRRRQRAISEILAAGGRYDLLIPQFRGPQALGPVP
TAVGVSIAIDKISAAILNMEEPVTISSCDLLIVSVGQMSMSRAINLTQKLWSAGITAQIM
YDWSQSQEELQEYCRYHEITYVALVSDKGGSYVKVKSFEKERQTEKLVQESDLIDHVLQK
LRTKVSDERTIREASDNLAVQNLKGSFSNASGLFEIHGAAVVPIVSVIAPEKLSASTRRR
YETQVQTRLQTSLANLHQKSNEIEILAVDLPKETILQFLSLEWDADEQAFNTTVKQLLSR
LPKQRYLKLVCDEIYNIKVEKKVSVLFLYSYRDDYYRILF
NT seq
4803 nt
NT seq
+upstream
nt +downstream
nt
atggctgggggccgtggggcccccgggcgcggccgggacgagcctccggagagctacccg
cagcggcaggagcacgagctgcaggccctggaggccatctacggcgccgacttccaggac
ctgcggccggacgcgcgcaaatcggtcaacgagccccctgaaatcaacttagttctgtac
cctcagggcctaactggtgaagaagtatacgtgcaagtggatttgagggttaaatgccca
ccaacctacccagatgtagtccctgaaatagagttaaagaatgccaaaggtctatcaaat
gaaagtgttcatttgttaaaatcccacctagagaaagtggccaaaaaacattgtggagag
caacgtgaaatccttcatgagattcaaagaaggaaagaagagataaaagaagagagaaaa
agaaaagaaatggctaagcaggagcgtttggaaattgctagtttgtcaaaccaagatcaa
aactctaggaaagacccaggaggacacagaatatctgccattctacatggaggctctcct
gactttgtaggaaatggtaaacatcggaccaactcctctggaaggtctaggcgagaacgt
cagtattctctgtgtagtagtgaagattcttctggctcttgtgaagtcctgtatttctct
atgggtagccctgatcagctcatggtttacaaagggaggtgcattggcagtgatgagcag
cttggaaaattagtttataatgctttggaaacggccactggcaactttgtgtcattacat
gagtgggtccttcggtggcagaaaaaaatgggcccgttccttaccagtcaagagaaggag
aagattgataagtgcaaaaagcagattcaaggggcagaaacggaattcaactcactggta
aaattgagccatccaaatgtagtacgctactttgcaatgaatctcaaagagcaagatgac
tccatcatggtggacattttattggagcacattaatggggtctccctctctgcacatctg
agccactcaggccccatccctgtgtatcaactccgcaagtacacagctcagctcttgtct
ggcctcgattatttgcacagcaatgacgtggtgcacaaggttctgaatgcatcaaatgtc
ttggtggatgcagagggcaatgtcaagattacggactacagcatttcaaagcgcctagca
gacatttgcaaggaggatgtgtttgagcagagccgagttagttttagtgacagtgcccta
ccttataaaacggggaagaaaggggatgtttggtgtcttggccttctgctgctcttcctc
agccaaggacaagaatgcggagagtaccctgtgaccatccctagcgacttaccagctgac
ttccaagattttctaaagaagtgtgtttgcttggatgacaaggaaagatggagtccccag
caattgttgaaacacagctttatcaatccacagccgaaaatgtctttattggaacagagt
cctgacgattctggaggacaagattatgttgagactgttattcctagtaagcagctaccc
agtgcagcattcttcagtgagacacagagacagttttcccggtatttcattgagtttgaa
gaattacagcttctcggcaaaggagccttcggagctgtcatcaaggtgcagaacaagctg
gatggctgctgctacgcggtgaagcgcatccccatcaatccggccagtaggcatttccgc
aggatcaagggcgaggtgacgctgctgtcgcgcctgcaccacgagaacatagtgcgctac
tataacgcctggatagagagatacgagcggcccgtgggcccggggatgctgccgcaggac
tcggactcatggccccaggcaccggatgggcgagctttgtcccagccgtccccaggcaac
gacagccccgacggcgacggcgccggtagcgtggaggccgctgcgccaccgcccatcctc
agctcggtggagtggagcacatctggcgagcgttcggccagcgcccgcttcccctccgcc
cgcccaggctccagcagcgaggaggacgacgacgacgacgagcacgagggcgtcttctcc
cagcccttcctacctgcttcagattctgacagtgatgtcatctttgaagatgagaacagt
aagagtcagaatcaggaagaagactgcaatgggaagaacagttgccatgaaagtgagcca
tcgacaaccactgaagctgtgcactacctgtatatccagatggagtactgtgagaagagt
actttgcgtgacaccattgaccaggggctatatcaagataccatcagactctggaggctt
tttcgagagattctggatggattagcttatatccatgaaaaaggaatgattcaccgggat
ttgaagcctgtcaacatctttttggattctgatgaccatgtaaaaataggtgattttggt
ttagcgacagaccatcttgccttcactgctgatggcaagcaagatgatacagcagatcac
ttgattaaatcagacccctcaggtcatttgactgggatggttggtactgctttatacgta
agcccagaggtccaaggaagcagcagacccacgtacaaccagaaagtggatctcttcagc
ctgggaattatcttctttgagatgtcctatcaccccatggtcacggcctcagaaaggatc
tttgttctcaaccaactcagagatcccacttcacctaagtttccagaagacttcgatgat
ggagagcatacaaagcagaaatctgtcatctcctggctgttgaaccatgatcccgccaag
cggcccacagccacagagctgctcaagagtgagctgctgcccccaccccagatggaggag
tcagagttgcatgaggttctgcaccacaccctggccaacgtggatgggaaggcctaccgc
accatgatggcccagatcttctcccagcgcgtcagtccagccatcgattacacctatgac
agcaacatgccgaagggcttttcaatccgtacatccaagatacagcaacatgtgtgtgat
accatcgtccgcatttttaaaaaacacggagctgtccagttgtgtactccactactgctt
ccccaaaataggcaaatatacgagcacaatgaagctgccttattcatggaccacagcggg
atgctggtgatgcttccctttgacctacgggttccttttgcaagatatgtggcaagaaat
aatatattgaatttgaaacgttactgcatagaacgtgtcttcagacctcgcaagttagac
cgatttcatcccaaagaacttctggaatgtgcatttgacattgttacgtctaccaccaac
agctctctgcccactgctgaagtcatctacacgatctgtgagatcatccaggagttcccg
gcactgcaggaaagaaattacagtatttacttgaaccacaccatgttattgaaagcaatc
ttcttacactgtgggatcccagaagataaactcagtcaagtctatgttattctatatgat
gcagtgacagaaaagctgacaaggagagaagtggaagccaagttttgtaatctgtctctg
tcatctaatagtctgtgtcgactctacaaattcattgagcagaagggagatttgcaagat
ctaacaccagcaataaattcattaataaaacagaaaacaggtgttgcccaactggtgaag
tatggcttgaaagacttagaggagatcattgggctgttgaagaaactcggcatcaagtta
caggtcttgatcaacttgggcttggtttacaaagtacagcagcacaacggagtcatcttc
cagtttgtggcggtcatcagacggaggcaaagggctatttcagaaatccttgcagctgga
ggcagatacgacctgctgattccccagtttagaggaccgcaggctctgggaccagtcccg
actgctgttggggtcagcatagccatagacaagatatctgcagctatcctcaacatggaa
gaacctgttacaataagctcttgtgacctcctgatcgtaagtgttggccagatgtccatg
tccagggccatcaacctaacccagaaactttggtcagcaggaatcacagcacagatcatg
tacgactggtcacagtcccaagaagaactccaggaatactgcagataccacgaaatcacc
tacgtggccctcgtctcagataaaggaggaagctatgtcaaggttaagtcttttgagaag
gaaaggcaaacagagaaacttgtgcaggagtctgatcttatagaccacgttttgcagaaa
ctcagaactaaagtcagtgatgaaaggactatcagagaagcttctgataatctcgcagtg
caaaatctgaaggggtccttttctaatgcttcaggtttgtttgaaatccacggagcagca
gttgtccccattgtgagcgtgatagccccagagaagctgtcagccagcacgaggaggcgt
tatgaaactcaggtacaaacacgacttcagacctcccttgccaacttacatcagaaaagc
aatgaaattgaaattttggctgtggatctacccaaagaaacaatcttacagtttttatcg
ttagagtgggatgctgatgaacaggcatttaacacaactgtgaagcagctgctgtcacgc
ctgccaaagcagagatacctcaaattagtctgtgatgaaatttataacatcaaagtagag
aaaaaggtatctgtgctattcctgtatagctacagagatgactactaccgaatcttattt
taa
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integrated database retrieval system
