KEGG   Canis lupus familiaris (dog): 478481
Entry
478481            CDS       T01007                                 
Symbol
HPGDS
Name
(RefSeq) hematopoietic prostaglandin D synthase
  KO
K04097  prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00480  Glutathione metabolism
cfa00590  Arachidonic acid metabolism
cfa00980  Metabolism of xenobiotics by cytochrome P450
cfa00982  Drug metabolism - cytochrome P450
cfa01100  Metabolic pathways
cfa05204  Chemical carcinogenesis - DNA adducts
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    478481 (HPGDS)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    478481 (HPGDS)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    478481 (HPGDS)
   00982 Drug metabolism - cytochrome P450
    478481 (HPGDS)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    478481 (HPGDS)
Enzymes [BR:cfa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     478481 (HPGDS)
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.99  Other intramolecular oxidoreductases
    5.3.99.2  prostaglandin-D synthase
     478481 (HPGDS)
SSDB
Motif
Pfam: GST_C_3 GST_N GST_N_2 GST_N_3 GST_C GST_C_6 Lipoprotein_8 GST_C_2 GST_N_4
Other DBs
NCBI-GeneID: 478481
NCBI-ProteinID: NP_001186973
Ensembl: ENSCAFG00000010032
VGNC: 54312
UniProt: E5RQH2 A0A8C0PBV7
LinkDB
Position
32:24752940..24777413
AA seq 199 aa
MPKYKLIYFNMRGRAEIIRYIFAYLDIKYEDHRIEQTDWPEVKSTLPFGKIPILEVDGLN
LHQSLAIARYMTKNTDLAGKTELEQCQVDAIVDTLDDFMSRFPWAEKNQDIKDQMFNELL
TYDGPHLLQDLDTYLGEKEWLIGDSVTWADFYWEICSTTLLVFKPDLLDIHPRLVTLRKK
VQAIPAIADWIQQRPQTKL
NT seq 600 nt   +upstreamnt  +downstreamnt
atgccaaaatataaactcatttattttaatatgagggggagagcagaaattattcgttac
atatttgcttatttggacataaagtatgaagaccacagaatagaacaaactgattggcct
gaagtcaaatcaactcttccatttggtaaaatccccattttggaagtcgatggacttaac
cttcaccagagcctagcaatagcaagatacatgaccaaaaacacagatctggctggaaaa
acagaattggaacaatgtcaagttgatgcgattgtggacacattggatgatttcatgtca
cgctttccttgggcagagaaaaatcaagatataaaagatcagatgtttaatgagctactt
acatatgatggacctcatcttctacaagatttggacacatacttaggggaaaaggagtgg
cttattggtgactctgtaacttgggcagatttctattgggaaatttgcagtaccacactt
ttggtctttaaacctgacttgctggacatccatcccaggttggtaacattacggaaaaaa
gttcaagccatccctgccattgctgactggatacaacaaaggccccaaaccaaactctaa

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