Canis lupus familiaris (dog): 478645
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Entry
478645 CDS
T01007
Symbol
MCCC1
Name
(RefSeq) methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial isoform X2
KO
K01968
3-methylcrotonyl-CoA carboxylase alpha subunit [EC:
6.4.1.4
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00280
Valine, leucine and isoleucine degradation
cfa01100
Metabolic pathways
Module
cfa_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
478645 (MCCC1)
Enzymes [BR:
cfa01000
]
6. Ligases
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.4 methylcrotonoyl-CoA carboxylase
478645 (MCCC1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
CPSase_L_D2
Biotin_carb_C
Biotin_carb_N
Biotin_lipoyl
Dala_Dala_lig_C
ATP-grasp
BSH_YknX
RimK
BSH_CusB
ATP-grasp_3
ATP-grasp_LDMS
BSH_RND
ATPgrasp_ST
GARS_A
ATP-grasp_4
BSH_CzcB
RnfC_N
NQRA_N
BT_MCC_alpha
BSH_YhbJ
Orn_DAP_Arg_deC
Motif
Other DBs
NCBI-GeneID:
478645
NCBI-ProteinID:
XP_038318687
Ensembl:
ENSCAFG00000011749
VGNC:
43070
LinkDB
All DBs
Position
34:complement(20111194..20173075)
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AA seq
639 aa
AA seq
DB search
MQQPQADEAYSIGPAPSQQSYLSMEKIIQVAKISAAQAIHPGYGFLSENMEFAELCKQEG
IIFVGPPSSAIKDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLREHAGKIGYPVMIKA
VRGGGGKGMRIVRSEEEFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQVFGDYHG
NAVYLFERDCSVQRRHQKIIEEAPGPGIKPDVRKKLGEAAVRAAKAVNYVGAGTVEFIMD
SKHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQGHAFEARI
YAEDPANNFMPGAGPLVHLSTPQGDLCTRIETGVRQGDEVSVHYDPMIAKLVVWATDRQA
ALTKLRYSLRQYHIVGLHTNIDFLLSLSGHPEFEAGNVHTDFIAQHHKELFPSKKATAKE
FLCQAALGLIFKEKAVSDALKIQSQDQYSPFASSSGRRLNIFYTRNITLRDGKNNVAIAV
TYNHDGSYSMQIEDKTFQVLGDLCNEGDCTYLKCSVNGVASKTKLIILENTIYLFSMEGS
AQIDIPPPKYLSSMSSGGTQGGTIAPMTGTIEKVFVKVGDKVKAGDSLMVMIAMKMEHAI
KAPKDGTIKKVFYKEGSQANRHAPLIEFEEEESDKRKTE
NT seq
1920 nt
NT seq
+upstream
nt +downstream
nt
atgcaacaaccacaggcagatgaggcatattccattggcccagctccctcacagcagagc
tacctttcaatggagaaaatcattcaagtggccaagatctccgctgcccaggctatccat
ccaggatacggttttctttcagaaaacatggaatttgccgaactgtgtaaacaagaagga
attatttttgtaggtcctccttcatctgcaattaaagacatgggtataaagagcacatcc
aaatccattatggctgctgccggagtgcctgttgtggaaggttatcatggcgaggaccag
tcagatcagtgcctgagggagcacgcggggaaaatcggttatcctgtcatgattaaagcc
gtccgtggtggaggaggaaaagggatgaggatcgttagatctgaggaagaatttcaagag
cagttagaatcagcacggagagaagctaagaagtctttcaatgatgatgcgatgctgatt
gagaagtttgtggacacgccaaggcatgtagaagtccaggtgtttggtgactatcatggc
aacgctgtgtacttgtttgaaagagactgtagtgtacagaggagacatcagaagatcatt
gaggaagccccagggcctggcattaaacctgatgtaagaaagaagcttggagaagctgca
gtcagagctgctaaagctgtaaattatgttggagcaggaactgttgagtttattatggac
tcaaagcacaatttctacttcatggaaatgaatacaagactgcaagtggaacatcctgtt
actgagatgatcacaggaactgacttggtggagtggcagcttaggattgcagcaggagag
aagattcctttgagccaggaagaaataactctgcagggccatgcctttgaagctagaata
tatgcagaagatcctgccaataacttcatgccaggggctgggcccttggtgcatctctcc
acccctcagggagacctttgtactagaatcgaaactggagtgagacaaggagatgaagtt
tcagtgcattatgaccccatgattgcgaagctggttgtatgggctacagatcgccaggca
gccttgacgaaactgaggtacagccttcgtcagtaccatatcgtcggactgcacaccaat
attgacttcctcctcagcctgtctggccacccagagtttgaagcaggcaatgtgcacact
gatttcattgctcaacaccacaaagagctgtttcccagtaagaaggccacagccaaggag
tttttatgccaggcagctctgggtctcatcttcaaggagaaagctgtgtctgatgctctc
aaaattcagtcacaagatcagtactcaccttttgcatccagcagtggaagaagactgaat
atcttttacaccagaaacataaccctgagggatggtaaaaacaatgtagccatagctgta
acatataatcatgatgggtcatatagcatgcagattgaagacaaaactttccaagtcctt
ggtgatctttgtaatgagggagactgcacttacctgaaatgttctgttaatggagttgct
agtaaaactaagctaattatcctggaaaacactatttacctattttccatggaaggaagt
gctcagattgacattccaccccccaaatacttgtcttcgatgagctcaggtggaactcag
ggaggtaccatagctcctatgactggtaccattgaaaaggtatttgtgaaagttggagac
aaagtaaaagctggagattctctaatggttatgattgccatgaaaatggagcatgccata
aaggctccaaaggatggcacgatcaagaaagtgttctacaaagaaggttctcaggccaac
agacatgctcctttaatcgaatttgaggaagaggagtctgacaaaagaaaaacagaataa
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