Canis lupus familiaris (dog): 478880
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Entry
478880 CDS
T01007
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00190
Oxidative phosphorylation
cfa01100
Metabolic pathways
cfa04714
Thermogenesis
cfa04723
Retrograde endocannabinoid signaling
cfa04932
Non-alcoholic fatty liver disease
cfa05010
Alzheimer disease
cfa05012
Parkinson disease
cfa05014
Amyotrophic lateral sclerosis
cfa05016
Huntington disease
cfa05020
Prion disease
cfa05022
Pathways of neurodegeneration - multiple diseases
cfa05208
Chemical carcinogenesis - reactive oxygen species
cfa05415
Diabetic cardiomyopathy
Module
cfa_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
478880 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
478880 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
478880 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
478880 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
478880 (NDUFS1)
05012 Parkinson disease
478880 (NDUFS1)
05014 Amyotrophic lateral sclerosis
478880 (NDUFS1)
05016 Huntington disease
478880 (NDUFS1)
05020 Prion disease
478880 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
478880 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
478880 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
478880 (NDUFS1)
Enzymes [BR:
cfa01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
478880 (NDUFS1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
478880
NCBI-ProteinID:
XP_038319512
Ensembl:
ENSCAFG00000013333
VGNC:
57390
UniProt:
A0A8I3S1V9
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Position
37:complement(15557654..15590612)
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AA seq
727 aa
AA seq
DB search
MLRIPLRRALVGLSKSPKGCVRTTATTASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSIAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTTWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDLLNR
VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIAFGSHPFNEVLNEAKKPMVVLGSSA
LQRNDGAAILAAVSSIAQKIRMSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKILRALSEIAGMTLPYDTLDQVRHRLEEVSPNLVRYDDVE
GANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
IEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctctaagaagggccttagtaggcctttctaagtctcctaaaggatgt
gttcgaacaactgctacaacagcaagcaacttaattgaagtatttgttgatggtcagtct
gtcatggtggaaccaggaactactgtcctccaagcttgtgagaaggttggcatgcagatt
cctcgattctgttatcatgaaagattgtctattgctggaaactgcaggatgtgcctggtt
gaaattgagaaagctcctaaggttgtagctgcttgtgccatgccagtaatgaaaggttgg
aatatcctaacaaactcagagaaatctaagaaagccagagaaggtgtgatggagttctta
ttagcaaatcacccactggactgtcctatttgtgaccagggaggtgaatgtgatctgcag
gaccaatccatgatgtttggaagtgataggagccgatttttagagggaaaacgtgctgtg
gaggacaaaaacattggaccattggtaaagaccattatgactagatgtatacagtgtact
cgctgcatcaggtttgcaagtgagattgcaggagtagatgatttgggaacaacaggcaga
ggaaatgatatgcaggttggcacgtacattgaaaagatgttcatgtctgaactgtctggc
aatatcattgacatctgccctgtaggtgccctgacctctaagccctatgcttttactgcc
cgcccttgggaaacaagaaagacggaatccattgatgtcatggatgcggttggaagtaat
attgtggtaagcacaagaacaggagaggtgatgaggattttgccaagaatgcatgaggac
atcaatgaagagtggatctctgataaaaccagatttgcttatgatgggctaaaacgtcaa
agacttactgagccgatggtcagaaacgaaaaggggcttttaacctataccacctgggag
gatgcactctctcgtgtagctggaatgttgcagagttttcaaggcaaggatgtagcagca
attgcaggtggcttggtggatgctgaagccctagtagctcttaaagatttgcttaataga
gtggactctgacactttgtgcacagaagaggtcttccccactgcaggagctggcacagat
ttgcgttccaattatcttcttaatactacaattgctggtgtggaagaggcagatgttgtc
cttctggttggtacaaatccacgttttgaggcaccactatttaatgctagaattcgaaag
agctggcttcacaatgacttaaaagtggcccttattggcagcccagtggacctcacttac
agatatgaccatctgggagattctcccaaaattcttcaagacattgcttttggtagccat
ccattcaatgaggtattaaatgaagctaaaaaaccaatggtggttttaggcagttctgca
ctccaaagaaatgatggggcagcaattcttgcagctgtttccagcattgctcaaaagatt
cggatgagtagtggtgttactggtgattggaaagttatgaatatccttcataggattgca
agccaagtagctgctttggaccttggctataaacccggggtggaagcaattcgtaagaac
cctcccaaagtgctatttctcctgggagcagatggaggttgtatcactcgacaggatttg
ccaaaggattgtttcattatttatcaaggacatcatggtgacgttggtgctcctatagct
gatgttattctcccaggcgctgcttatacggagaaatctgctacctatgtcaatactgag
ggccgagctcagcagactaaagtagcagtgacacctcctggcttggcaagagaagactgg
aaaattctaagagccctctctgagattgcaggtatgacccttccatatgatactttggat
caagtaaggcacagattggaagaagtctctcctaatcttgtccgatatgatgatgtggaa
ggagccaattatttccagcaagcaaatgagctctccaagctagtgaaccagcaacttctt
gctgatccacttgttccacctcagctaacaataaaagacttctacatgacagactccatt
agcagagcctcacagacaatggctaaatgtgtcaaagctgtcacagagggtgcccaggca
atagaggaaccatccatatgctga
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