Canis lupus familiaris (dog): 478889
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Entry
478889 CDS
T01007
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00020
Citrate cycle (TCA cycle)
cfa00480
Glutathione metabolism
cfa01100
Metabolic pathways
cfa01200
Carbon metabolism
cfa01210
2-Oxocarboxylic acid metabolism
cfa01230
Biosynthesis of amino acids
cfa04146
Peroxisome
cfa05230
Central carbon metabolism in cancer
Module
cfa_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
478889 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
478889 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
478889 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
478889 (IDH1)
Enzymes [BR:
cfa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
478889 (IDH1)
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
XRN1_D2_D3
Motif
Other DBs
NCBI-GeneID:
478889
NCBI-ProteinID:
XP_013966568
Ensembl:
ENSCAFG00000013617
UniProt:
F1PZA1
A0A8C0MYC5
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Position
37:complement(17394694..17413933)
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AA seq
414 aa
AA seq
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MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE
EVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtcacaaaaaatccgtggtggttctgtggtggagatgcaaggagatgaaatgacacga
atcatttgggagttgattaaagaaaaactcatttttccctacgtggaactggacctgcac
agctatgatttaggcatagagaatcgcgatgccaccaatgaccaggtcaccaaggatgct
gcagaagctataaagaagtacaacgttggtgtcaagtgtgctaccatcacccccgatgaa
aagagggttgaggagttcaagttgaaacaaatgtggaaatcaccaaatggcaccatccga
aatattctgggtggcactgtcttcagggaagctattatctgcaaaaacatcccccggctt
gtgagcggatgggtaaaacccatcatcataggtcgtcatgcttatggggatcaatacaga
gcaactgattttgttgttcccgggcctggtaaagtagagataacctacacgcccagtgat
ggatctgaaaaaatgacctacctggtacataactttgaagagggtggtggtgtggccatg
gggatgtacaatcaagataagtcgattgaagattttgcacacagttctttccagatggct
ctgtctaagagttggcctttgtatctgagcaccaaaaacactattctgaaaaaatatgat
ggacgttttaaggacatctttcaggaaatatatgacaagcagtataaatcccaattcgaa
gcccagaacatctggtatgagcataggctcattgatgacatggtggcccaagctatgaaa
tccgagggaggctttatctgggcctgtaaaaactatgatggcgacgtgcagtcggactcc
gtggcccaaggttacggctctcttggcatgatgaccagcgtgctggtttgtccagacggc
aagacagtagaagcagaggctgcccatgggactgtaacacgtcactaccgcatgtatcag
aaaggccaggagacgtccaccaatcccattgcttccatttttgcctggaccagagggtta
gcccacagagctaagcttgataacaacaaagagctcagcttctttgcaaaggctttggaa
gaagtctgtgttgagaccattgaggctggcttcatgaccaaggacttggctgcttgtatt
aaaggtttgcccaatgtgcaacgttctgactacttgaatacatttgagttcatggacaaa
cttggagaaaacttgaatataaaactagctcaggccaaactgtaa
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