Canis lupus familiaris (dog): 478910
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Entry
478910 CDS
T01007
Symbol
PLCD4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X2
KO
K05857
phosphatidylinositol phospholipase C, delta [EC:
3.1.4.11
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00562
Inositol phosphate metabolism
cfa01100
Metabolic pathways
cfa04020
Calcium signaling pathway
cfa04070
Phosphatidylinositol signaling system
cfa04919
Thyroid hormone signaling pathway
cfa04933
AGE-RAGE signaling pathway in diabetic complications
Module
cfa_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
478910 (PLCD4)
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
478910 (PLCD4)
04070 Phosphatidylinositol signaling system
478910 (PLCD4)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
478910 (PLCD4)
09160 Human Diseases
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
478910 (PLCD4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cfa04131
]
478910 (PLCD4)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
478910 (PLCD4)
Membrane trafficking [BR:
cfa04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
478910 (PLCD4)
Endocytosis
Macropinocytosis
Phospholipase C
478910 (PLCD4)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
EF-hand_like
EF-hand_10
C2
EF-hand_7
EF-hand_1
EF-hand_6
EF-hand_5
PH
PH_12
EF_HAND_2_PLCG
GDPD
EF-hand_15
EF-hand_8
Wap1
Trypan_PARP
Motif
Other DBs
NCBI-GeneID:
478910
NCBI-ProteinID:
XP_005640708
Ensembl:
ENSCAFG00000014832
VGNC:
44649
UniProt:
A0A8I3Q2Q7
LinkDB
All DBs
Position
37
Genome browser
AA seq
767 aa
AA seq
DB search
MASLMQSRLPINQDLMLMQKGMLMRKVRSKCWKKLRYFRLQDDGMTVWHARQEGGNAKPT
FSISDVETVREGHESELLRSLAEEFPLERGFTIIFHGRRANLDLVANSVEEAEVWKRGLW
HLMDFVNGMDQQERLDQWLSDWFQRGDKNQDGRMSFQEVQRLLHLMNVEMDQEYAFHLFQ
TADTSHSGTLEGEEFVDFYKALTKRAEVQELFENFSADGQKLTLLEFVDFLREEQKEGER
APDLALELIDRYEPSESGKLRHVLSMDGFLSYLCSKDGDIFKPTCLPIYQDMTQPLNNYY
INSSHNTYLVGDQLYGQSSVEGYIRALKRGCRCVEVDIWDGPSGEPIVYHGHTLTSRIPF
KDVVATVAQYAFQTSEYPVILSLENHCSWEQQQVMACHLTEILGEQLLSTTLDGLLPTQL
PSPEELRRKILVKGKKLRTLEEDLEEEEEEELESELEGEQEADPEPEAQLESEPQELSPR
SKDKKKEKKSKPILCPSLSALVVYLKSVSFHSFTHSREHYRFYETSSFSETKAKSLIKEA
GNEFVQHNAWQLSRVYPSGLRTDSSNYNPQELWNAGCQMVAMNVQTAGLEMDICDGLFRQ
NGGCGYVLKPDFLRDAQSSFHPERPVSPFRAQTLLIQVISGQQLPKEDMSKERSIVDPLV
RVEIFGVRPDTTRQETSYVENNGFNPYWGQTLCFRVLVPELALLRFVVKDYNWKSRNDFI
GQYTLPWTCMQQGYRHIHLLSKDGTSLHPASIFVHINIREGLEGDEC
NT seq
2304 nt
NT seq
+upstream
nt +downstream
nt
atggcgtctctgatgcaaagccggttgcctatcaatcaagacctgatgctgatgcagaag
ggcatgctgatgcgcaaggtgagatccaaatgctggaagaaactaagatacttcagactt
caagatgatggcatgacagtctggcatgcccggcaggaaggaggcaatgccaagcccacc
ttctcaatctctgatgtggagacagtacgtgagggccatgagtctgagctgctacgcagc
ctggcagaggagttccccctggagcggggcttcaccatcatcttccacggccgccgtgcc
aacctggacctggtggccaacagtgtcgaggaggccgaggtatggaagcgggggctctgg
catctgatggactttgtcaacggcatggaccaacaggagcggctggaccaatggctgagt
gactggttccagcgtggagacaagaaccaggatggtcggatgagtttccaagaagtccag
cgattactgcacctgatgaatgtggaaatggatcaagaatatgccttccatcttttccaa
acagcagacacgtcccattctgggaccctggaaggagaagaatttgtagacttctataag
gcgctgactaaacgtgctgaggtgcaggagctgtttgaaaacttttcggctgatgggcag
aagctgaccctgctggaatttgtggatttcctccgagaggagcagaaagaaggagaacga
gctcctgaccttgctctggaactcatcgaccgctatgagccctcagagagcggtaaattg
cgacatgtgctgagcatggatggcttcctcagctacctctgctcaaaggacggagatatc
ttcaagccgacctgcctccccatctaccaggatatgactcaacccctgaacaactactac
atcaactcctctcacaacacttacctcgtgggggaccagctttatggccagagcagcgtc
gagggatatatacgggccctgaagagggggtgccgctgcgtggaggtggatatatgggat
ggacctagcggggaacctattgtttaccatggacacaccctgacttcccgcatcccattc
aaagatgtcgtggccactgtagcacagtatgccttccagacatccgaatacccggtcatc
ttgtccctggagaaccactgcagctgggagcagcagcaggtcatggcatgccatctgacc
gagatcttgggggagcagctgctgagcaccaccttggacgggctgctgcccactcagctg
ccctcacctgaggagcttcggaggaagatcctggtgaaggggaagaagttaaggacactt
gaggaggatcttgaggaagaggaagaggaggagctagaatctgaactggagggggagcag
gaggctgacccagagccagaggcccagttggagtctgagccccaggagttgagtccacgt
agtaaggacaaaaagaaggagaagaaatccaaacccatcttgtgcccatccctctctgcc
ctggttgtctacttgaagtcggtctcattccacagcttcactcattcgagggagcactac
cgcttctatgagacatcatctttctctgaaaccaaggccaagagcctcatcaaggaggct
ggcaatgagttcgtgcagcacaacgcctggcagttaagccgtgtgtatcccagtggcctg
aggacggattcgtccaactacaacccccaggaactctggaatgcaggctgccagatggtg
gccatgaacgtgcagaccgcggggctggagatggacatctgtgacgggctcttccgccag
aacggtggctgcggctatgtgctgaagccagacttcctgcgcgatgcccagagttccttc
caccctgagaggcccgtcagccctttcagagcccagaccctcctcatccaggtgatcagt
gggcagcaactccccaaggaggacatgtctaaagagcggtccattgtggatccactggtg
agagtagagatctttggcgtccgcccggacacaacccggcaagagaccagctacgtggag
aacaacggttttaatccatactgggggcagacactatgcttccgggtcctggtgcctgaa
ctggccctgctgcgtttcgtggtcaaggattacaactggaaatcccgaaatgattttatc
gggcagtacacactaccttggacctgcatgcagcaaggctaccgccacatacacctgctc
tccaaggatggcaccagcctccacccagcttccatcttcgtgcatatcaacatccgggaa
gggctggagggggatgaatgctaa
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