Canis lupus familiaris (dog): 478981
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Entry
478981 CDS
T01007
Symbol
NDUFS2
Name
(RefSeq) NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X1
KO
K03935
NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:
7.1.1.2
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00190
Oxidative phosphorylation
cfa01100
Metabolic pathways
cfa04714
Thermogenesis
cfa04723
Retrograde endocannabinoid signaling
cfa04932
Non-alcoholic fatty liver disease
cfa05010
Alzheimer disease
cfa05012
Parkinson disease
cfa05014
Amyotrophic lateral sclerosis
cfa05016
Huntington disease
cfa05020
Prion disease
cfa05022
Pathways of neurodegeneration - multiple diseases
cfa05208
Chemical carcinogenesis - reactive oxygen species
cfa05415
Diabetic cardiomyopathy
Module
cfa_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
478981 (NDUFS2)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
478981 (NDUFS2)
09159 Environmental adaptation
04714 Thermogenesis
478981 (NDUFS2)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
478981 (NDUFS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
478981 (NDUFS2)
05012 Parkinson disease
478981 (NDUFS2)
05014 Amyotrophic lateral sclerosis
478981 (NDUFS2)
05016 Huntington disease
478981 (NDUFS2)
05020 Prion disease
478981 (NDUFS2)
05022 Pathways of neurodegeneration - multiple diseases
478981 (NDUFS2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
478981 (NDUFS2)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
478981 (NDUFS2)
Enzymes [BR:
cfa01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
478981 (NDUFS2)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Complex1_49kDa
NiFeSe_Hases
Motif
Other DBs
NCBI-GeneID:
478981
NCBI-ProteinID:
XP_536138
Ensembl:
ENSCAFG00000012850
VGNC:
43707
UniProt:
A0A8C0RNV5
A0A8I3Q1H1
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All DBs
Position
38:complement(21346459..21356011)
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AA seq
463 aa
AA seq
DB search
MAALRALRSLRGAAAQALRSGAGGRLPLQPSRGARQWQPDVEWAEQFGGAVMYPTKETAH
WKPPPWNDVDPPKDTMVTNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGT
EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRL
LNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYVRPGGVHQDLPLGL
MDDIYEFSKNFSLRVDELEEMLTNNRIWKNRTVDIGVVTAEDALNYGFSGVMLRGSGIQW
DLRKTQPYDVYDQVDFDVPIGSRGDCYDRYLCRVEEMRQSLRIIEQCLNKMPPGEIKVDD
AKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY
RCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagggctttgcgcagcctccggggcgccgcggcccaggcgctgcggtcg
ggggccggcggccggctgccgcttcagcccagcagaggtgctcggcagtggcagccagat
gtggaatgggcagagcagtttgggggagctgtcatgtaccccaccaaagaaacagcccac
tggaagcctccaccttggaacgacgtggaccctccaaaggacacaatggtgacaaacctg
accctgaactttgggccccagcacccagcggctcatggagtcctgcggctagtgatggag
ttgagcggggagatggtgcggaagtgtgacccccacatcggcctactacaccgaggcact
gagaagctcattgaatacaagacctatctgcaggcccttccatactttgaccgtctagac
tacgtgtccatgatgtgtaacgaacaggcctattcgctggccgtggagaagttgctcaat
atccagcctccgccacgggcacagtggatccgagtgctatttggagaaatcacacggctc
ttgaaccacattatggctgtgactacacatgccctggacattggagccatgacccctttc
ttctggatgtttgaagagagggagaagatgtttgaattctacgagcgcgtgtcaggggcc
cgcatgcatgctgcttatgtccggccaggaggtgtgcaccaggacctgcccctcgggctt
atggacgacatctatgagttttctaagaacttctctctccgggttgatgagctggaagag
atgctgaccaacaataggatttggaagaatcggacagttgacattggggttgtgacggcc
gaagacgcgctgaactatggatttagtggcgtgatgctccggggctcgggcatccagtgg
gacctgcggaagactcagccctatgacgtttatgaccaggtggacttcgatgttcctatt
ggctctcgaggggactgctatgacaggtacctgtgtcgggtggaggagatgcgccagtcc
cttcgaatcatcgagcaatgtctgaacaagatgcctcccggggagatcaaggttgatgat
gccaaagtgtctccgccgaagcgagcagagatgaagacttccatggagtcattgatccac
cacttcaagttgtacacggagggctaccaggtccctccgggggccacgtacactgccatc
gaggctcctaagggagagtttggggtgtacctcgtgtccgatggcagcagccgcccttac
cgatgcaagatcaaggctcctggttttgcccacctggctggtttggacaagatgtccaag
ggacacatgctggcggacgttgttgccatcataggtacccaagatatcgtgtttggagaa
gtggatcggtga
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