Canis lupus familiaris (dog): 479351
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Entry
479351 CDS
T01007
Symbol
PRKAA1
Name
(RefSeq) 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1
KO
K07198
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:
2.7.11.31
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04068
FoxO signaling pathway
cfa04140
Autophagy - animal
cfa04150
mTOR signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa04152
AMPK signaling pathway
cfa04211
Longevity regulating pathway
cfa04213
Longevity regulating pathway - multiple species
cfa04371
Apelin signaling pathway
cfa04530
Tight junction
cfa04710
Circadian rhythm
cfa04714
Thermogenesis
cfa04910
Insulin signaling pathway
cfa04920
Adipocytokine signaling pathway
cfa04921
Oxytocin signaling pathway
cfa04922
Glucagon signaling pathway
cfa04931
Insulin resistance
cfa04932
Non-alcoholic fatty liver disease
cfa04936
Alcoholic liver disease
cfa05410
Hypertrophic cardiomyopathy
cfa05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
479351 (PRKAA1)
04068 FoxO signaling pathway
479351 (PRKAA1)
04151 PI3K-Akt signaling pathway
479351 (PRKAA1)
04152 AMPK signaling pathway
479351 (PRKAA1)
04150 mTOR signaling pathway
479351 (PRKAA1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
479351 (PRKAA1)
09144 Cellular community - eukaryotes
04530 Tight junction
479351 (PRKAA1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
479351 (PRKAA1)
04922 Glucagon signaling pathway
479351 (PRKAA1)
04920 Adipocytokine signaling pathway
479351 (PRKAA1)
04921 Oxytocin signaling pathway
479351 (PRKAA1)
09149 Aging
04211 Longevity regulating pathway
479351 (PRKAA1)
04213 Longevity regulating pathway - multiple species
479351 (PRKAA1)
09159 Environmental adaptation
04710 Circadian rhythm
479351 (PRKAA1)
04714 Thermogenesis
479351 (PRKAA1)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
479351 (PRKAA1)
05410 Hypertrophic cardiomyopathy
479351 (PRKAA1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
479351 (PRKAA1)
04932 Non-alcoholic fatty liver disease
479351 (PRKAA1)
04931 Insulin resistance
479351 (PRKAA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
479351 (PRKAA1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cfa04131
]
479351 (PRKAA1)
03029 Mitochondrial biogenesis [BR:
cfa03029
]
479351 (PRKAA1)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
479351 (PRKAA1)
Protein kinases [BR:
cfa01001
]
Serine/threonine kinases: CAMK group
CAMKL family
479351 (PRKAA1)
Membrane trafficking [BR:
cfa04131
]
Autophagy
Other autophagy associated proteins
Others
479351 (PRKAA1)
Mitochondrial biogenesis [BR:
cfa03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
479351 (PRKAA1)
Mitophagy factors
Other mitophagy factors
479351 (PRKAA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
AMPK_alpha_AID
AdenylateSensor
Kinase-like
ABC1
FTA2
Motif
Other DBs
NCBI-GeneID:
479351
NCBI-ProteinID:
XP_022273603
Ensembl:
ENSCAFG00000018614
VGNC:
51914
LinkDB
All DBs
Position
4:68255490..68291515
Genome browser
AA seq
573 aa
AA seq
DB search
MAPLAAPGVVRVSVPSRRFSPYLPGPILSVRWVPPPQPPPEIGKHELTGHKVAVKILNRQ
KIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGR
KSDVPGVVRTGFMKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKI
ADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFD
DDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKY
LFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMN
EAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAK
WHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVD
SRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRNDSDAEAQGKSSEASLTSSVT
SLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
NT seq
1722 nt
NT seq
+upstream
nt +downstream
nt
atggcccccctggcggcgcccggggtcgtccgcgtttccgtcccctctaggaggttctcc
ccttacctgccggggccgattcttagtgtgcgatgggtgccccctcctcagcctccccca
gaaattggcaaacatgaattgactgggcataaagttgctgtgaagatactcaatcgacag
aagattcgaagccttgatgtggtaggaaaaatccgcagagaaattcagaacctcaagctt
ttcaggcatcctcatataattaaactgtaccaggtcatcagtacaccatctgatattttc
atggtgatggaatatgtctcaggaggagagctatttgattatatctgtaaaaatggaagg
aaatctgatgtacctggagtagtaagaacaggcttcatgaaggagctggatgaaaaagaa
agtcggcgtctgtttcaacagatcctttctggtgtggattactgtcacaggcatatggtg
gtccatagagatttgaaacctgaaaatgtcttgcttgatgcacacatgaatgcaaagata
gctgattttggtctttcaaacatgatgtcagatggtgaatttttaagaacaagttgtggc
tcacccaactatgctgcaccagaagtaatttcaggaagattgtatgcaggtccagaggta
gatatatggagcagtggggttattctctatgctttattatgtggaacccttccatttgat
gatgatcatgtgccaactctttttaagaagatatgtgatgggatcttttatacccctcag
tatttaaatccatctgtgattagccttttgaaacatatgctccaggtggatcccatgaag
agggccacaatcaaagatatcagggaacatgaatggtttaaacaagaccttccaaaatac
ctttttcccgaggatccatcgtatagttcaactatgattgatgatgaagccttaaaagaa
gtatgtgaaaaatttgagtgctcagaagaggaagttctcagctgcctttataacagaaat
caccaggaccctttagcagttgcctaccaccttataatagataacaggagaataatgaat
gaggccaaagatttttacttggcaacaagcccacctgattcttttctcgatgatcaccat
ttgactcggccccatcctgaaagagtaccattcttggttgctgaaacacctagggcacgc
cacactctcgatgaattaaatccacagaaatctaagcaccaaggtgtaaggaaagcaaaa
tggcatttgggaattagaagtcaaagtcgaccaaatgatatcatggcagaagtttgtagg
gcaattaaacaactggattatgaatggaaggttgtaaacccttattatttgcgtgttcga
aggaagaatcctgtgacaagcacctactccaaaatgagtctacagttataccaagtggat
agtagaacgtacttactggatttccgtagtatcgatgatgaaattactgaagccaaatca
gggactgctactccacagagatcgggatcagttagcaactatcgatcttgccaaaggaat
gattcagatgctgaggctcaaggaaaatcctcagaagcttctcttacctcatctgtgacc
tcacttgactcttctcctgttgatttaactccaagacctggaagtcacacaatagaattt
tttgagatgtgtgcaaatctaattaaaattcttgcacagtaa
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