Canis lupus familiaris (dog): 479409
Help
Entry
479409 CDS
T01007
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04270
Vascular smooth muscle contraction
cfa04360
Axon guidance
cfa04611
Platelet activation
cfa04625
C-type lectin receptor signaling pathway
cfa04810
Regulation of actin cytoskeleton
cfa05135
Yersinia infection
cfa05152
Tuberculosis
cfa05163
Human cytomegalovirus infection
cfa05200
Pathways in cancer
cfa05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
479409 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
479409 (ARHGEF12)
04625 C-type lectin receptor signaling pathway
479409 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
479409 (ARHGEF12)
09158 Development and regeneration
04360 Axon guidance
479409 (ARHGEF12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
479409 (ARHGEF12)
05205 Proteoglycans in cancer
479409 (ARHGEF12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
479409 (ARHGEF12)
09171 Infectious disease: bacterial
05135 Yersinia infection
479409 (ARHGEF12)
05152 Tuberculosis
479409 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cfa04131
]
479409 (ARHGEF12)
Membrane trafficking [BR:
cfa04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
479409 (ARHGEF12)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
AAA_23
Motif
Other DBs
NCBI-GeneID:
479409
NCBI-ProteinID:
XP_005619719
Ensembl:
ENSCAFG00000011934
VGNC:
38075
UniProt:
A0A8I3NRY3
LinkDB
All DBs
Position
5:complement(13572143..13722335)
Genome browser
AA seq
1543 aa
AA seq
DB search
MSGTQPTITDRFPLKKPIRHGSILNRESPTDKKQKVERSASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVVTSSKPVGEPLTASEVEADPGEGIGRLDYCTGDAS
RPGSDSADSPKSALKERICLEENPEKSEVIQDTDTQSLFGSPSPRIAAHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVSVPDEISVDLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRVTLEKERACAEQIVAKIEEVLMTAQPVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKQRHPKHLSTPSSVSPEPQDPAKLRQSALAGEGTEVGY
LPANPMSSVAAGATLSQEGGKENDTGSKQVGETPASGDCIDNTPRTPNTIFDFPPPPLDQ
VQEEEWEVERVTEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEDKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPMEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLNTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSAK
PIPLPQSPPCEGDNDEEAAPKLKVEHHSISVPGLQSPDRDLGLESPLISSKPQSHSLGTS
GKSEVDDLFVAERQFAKEQHTDGTLQEAGGSYQITIPDPHLPASEERWALDALRNLGLLK
QLLVQQLGLTEKSAQEDWPHFPRYRTASSGVQTDSGTQNSENSKAYPPGEGQMPFRTGTG
DISTCYSPRTSTESSAPRDSVVLAFQESQASNILVMDHMIMTPEMPPAEPEGSLDESGEH
FFDAREAHSDDNPSEGDGAVKKEEDVNLRISGNYLILDGYEAVQESSTDEEVASSLPPPP
TAGIPAMDCARPQQHSPQHAHSDGAASPFTPEFLVQQRWGAMEDSCFEIQSPPSCADSQS
QIMEYIRKIEADLEHLKKVEESYSILCQRLAGSALTDKHSDKS
NT seq
4632 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcacacagcccactatcaccgacaggtttcccctcaaaaaacctataaggcat
gggagtattttgaaccgagagtcaccaacagataagaagcagaaagttgagcgcagtgca
tcacatgattttgatcccacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatatatggtctggttcagcgttgtgtgatcatccagaaggatgacaat
ggatttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaagat
ggagcagccatgcgggctggggtacagacaggtgatcgaatcatcaaggtgaatggaact
ctggtgactcattcaaaccatttggaagtggtgaagctaatcaaatctggttcctatgta
gctctcactgttcagggacgcccacctgggtcgccccagattccactcgctgattctgaa
gtagagccatcagtcattggacatatgtctcccatcatgacatcccctcattcacctgga
gcatctgggaacatggagagaattactagtcctgtgctcatgggggaggaaaacaatgtg
gttcataaccagaaagtagaaattctgagaaagatgttacagaaagaacaggaacggcta
cagttattgcaggaagattacaaccgaacacctgcccaaagattgctaaaagagatccaa
gaggccaagaaacacattcctcagctgcaagagcagttatccaaagccacaggctctgct
caggatggagctgtagttacctcctccaagcctgtaggtgagccgctgacagccagtgag
gtagaagcagatcctggtgagggaataggcagacttgactactgcactggagatgcttct
cggcccggcagtgacagcgctgacagtcccaagagtgccctgaaagagaggatttgtcta
gaggaaaacccagagaaaagtgaagtgattcaggacactgatacccagtctctctttggg
agcccctctccccgtatagcagctcatattattggagcagaggatgatgatttcggtact
gaacatgaacagatcaatgggcagtgcagctgtttccagagcattgaactgctgaaatct
cgccctgctcacctggctgttttcttacaccatgtagtctcacagtttgaccccgccaca
ctgctttgttatctgtattcagacctgtataagcagaccaattccaaggagactcgtcgc
gtcttccttgagtttcatcagttcttcctggatcgatctgcacacctgaaagtttctgtg
cctgatgaaatatcagtagatctagaaaaaaggagacctgagcttatacctgaggatcta
caccgccactatatccaaacaatgcaggaaagagtccacccagaagttcagaggcacttg
gaggattttcggcagaagcgtagcatgggactgaccttggctgaaagcgagctgactaaa
ctcgacgcagagcgagacaaggaccgggtaactttggagaaggaacgggcatgtgcagaa
cagattgttgccaaaatcgaagaagtgttgatgactgctcagcctgtggaagaagataag
agttcaacaatgcagtatgttatcctaatgtacatgaagcatttgggggtaaaagtgaaa
gaacctcgaaatttggagcacaagcggggtcggattggattccttccaaaaatcaagcag
agtatgaagaaagatcgagaaggcgaagaaaaaggaaagcgcagaggattccccagcatc
ctgggacccccaaggagaccaagccgtcacgacaacagtgcaattggcagagccatggaa
ctacagaagcagcgccacccgaagcacttatccacaccttcttctgtgagtcctgagcct
caggaccctgccaagttgcgccagagtgcattagcaggcgaaggaacagaggtcggatac
ctgccagccaatcccatgtcctctgtggctgctggggccactctttcccaggaaggaggg
aaggagaatgatacaggatcaaagcaagttggagaaacaccagcatctggagactgcata
gataatacccctcggactcccaataccatctttgatttcccacctcctcccttagaccaa
gtgcaggaggaggaatgggaagtggaaagggtgactgagcatgggacaccaaaacccttt
cgaaagtttgacagcatagcttttggagaaagtcaaagtgaggatgaacagtttgaaaat
gacttagagacagatccacccaactggcaacagctcgttagtcgagaagtgttactgggc
ctaaagccttctgagatcaaaagacaggaagtaattaatgaattgttctacactgaaaga
gctcatgtccgaacactaaaggttcttgatcaagtattctatcagcgagtgtccagggaa
ggaattctgtccccttcagaactacggaagattttttcaaacttggaagatattcttcaa
cttcacattggattgaatgagcaaatgaaggctgttcgaaagaggaatgagacctcagtt
attgatcagattggggaagatttgctgacctggttcagtggaccaggggaggacaagctg
aagcacgccgctgctaccttttgcagtaaccaaccttttgccctggaaatgatcaagtct
cgtcagaaaaaggattctcgattccagacctttgtgcaagatgctgagagtaatcctctg
tgtcgtcgtctgcagctgaaggatatcattcctacccagatgcagaggcttaccaagtac
cctcttctgttggataatattgccaaatacacagaatggccaatggaaagggagaaggtg
aagaaagccgcagatcactgtcgtcagatcttaaattacgtaaatcaggctgtcaaggag
gcagaaaacaaacagcgactagaagactaccagcgtcgcctggatacctccaatctgaag
ttgtcagagtacccaaatgtggaagagctcaggaatttggatttaacgaaaaggaagatg
attcatgaagggccattggtctggaaggtgaatcgagataaaactattgatctatacaca
ttgctgctggaagacattcttgtattgttacaaaagcaggatgatagactggtgttaaga
tgtcatagtaagattctggcatccacggctgacagcaaacacacatttagccctgtcatt
aagttgaatacagtgttggttcgacaagtggcaacagataacaaagctttatttgtcatc
tccatgtcagacaatggagcccagatttatgaactggtggcacagactgtttctgaaaag
actgtctggcaagacctaatctgtcggatggctgcatcagtgaaggaacagtccgcaaag
ccaatcccattgccacagtcaccaccttgcgaaggagacaacgatgaagaagcagctcca
aagttaaaagtggaacatcatagcatttcagtccctggtttgcagagtccagacagagat
ttgggattagagtctcccttaatatcatcaaaacctcagtctcattcactgggtacctct
gggaaatccgaggtagatgatctgtttgtggccgagaggcagtttgctaaggagcagcat
acagatgggactctgcaggaagctggaggaagttatcagatcacaatcccagatccacac
ttgcctgcctccgaagaacggtgggcactggatgcactaaggaatttgggcttgctgaag
cagttgctcgtccaacagctgggtttgaccgagaagagtgctcaggaagactggccacat
ttcccgagatacaggacggcgtcttcaggggtgcagacagacagtggaacccagaactct
gaaaacagtaaggcctatcctcctggtgaaggacagatgccctttagaactggaactggt
gacatttcaacttgttacagtccacggacttccactgaatcttctgctccacgggattca
gtggtcctggcattccaagagagccaggcaagtaacattttagtaatggaccacatgatt
atgaccccagagatgcctcctgcagagccagaagggagtcttgatgagagtggagagcac
ttttttgatgcccgtgaagcacatagtgatgataatccatcagaaggtgatggagcagtt
aagaaggaagaggatgttaatttgcgcatctcaggaaactatttgattcttgatggctat
gaagcggtgcaggagagctccacggacgaggaggttgcttcctcgcttcccccgccgccc
acggcaggcatccccgccatggactgtgcccgcccacagcagcactctccccagcatgcc
cattccgatggggcggcttcaccattcaccccagaattcctggtccagcagcgctgggga
gctatggaggattcctgttttgagatccagagccccccctcttgtgcagactcacaaagc
cagatcatggagtacattcgtaagatcgaggctgacctagaacacctaaagaaggtggaa
gagagttacagcattctttgccaaaggctggctggatcagccctcacagacaagcactca
gataagagttag
DBGET
integrated database retrieval system
