Canis lupus familiaris (dog): 479797
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Entry
479797 CDS
T01007
Symbol
ATP2A1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04020
Calcium signaling pathway
cfa04022
cGMP-PKG signaling pathway
cfa04024
cAMP signaling pathway
cfa04148
Efferocytosis
cfa04260
Cardiac muscle contraction
cfa04261
Adrenergic signaling in cardiomyocytes
cfa04380
Osteoclast differentiation
cfa04919
Thyroid hormone signaling pathway
cfa04972
Pancreatic secretion
cfa05010
Alzheimer disease
cfa05017
Spinocerebellar ataxia
cfa05022
Pathways of neurodegeneration - multiple diseases
cfa05410
Hypertrophic cardiomyopathy
cfa05412
Arrhythmogenic right ventricular cardiomyopathy
cfa05414
Dilated cardiomyopathy
cfa05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
479797 (ATP2A1)
04024 cAMP signaling pathway
479797 (ATP2A1)
04022 cGMP-PKG signaling pathway
479797 (ATP2A1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
479797 (ATP2A1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
479797 (ATP2A1)
09153 Circulatory system
04260 Cardiac muscle contraction
479797 (ATP2A1)
04261 Adrenergic signaling in cardiomyocytes
479797 (ATP2A1)
09154 Digestive system
04972 Pancreatic secretion
479797 (ATP2A1)
09158 Development and regeneration
04380 Osteoclast differentiation
479797 (ATP2A1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
479797 (ATP2A1)
05017 Spinocerebellar ataxia
479797 (ATP2A1)
05022 Pathways of neurodegeneration - multiple diseases
479797 (ATP2A1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
479797 (ATP2A1)
05412 Arrhythmogenic right ventricular cardiomyopathy
479797 (ATP2A1)
05414 Dilated cardiomyopathy
479797 (ATP2A1)
05415 Diabetic cardiomyopathy
479797 (ATP2A1)
Enzymes [BR:
cfa01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
479797 (ATP2A1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
479797
NCBI-ProteinID:
XP_860010
Ensembl:
ENSCAFG00000017254
VGNC:
38253
UniProt:
A0A8C0PSX5
A0A8I3MNT3
LinkDB
All DBs
Position
6:19963150..19978140
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AA seq
1000 aa
AA seq
DB search
MEAAHSKTTEECLAYFGVSETTGLSPDQVKRHLEKYGPNELPAEEGKTLWELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGNLCVLNEFAITGSTYAPEGEVLKNDKPVRSGQYDGLVELATICALC
NDSALDFNETKGVYEKVGEATETALTTLVEKMNVFNTDVRNLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPV
KDKILSVIKEWGTGRDTLRCLALATRDTPPKREEMILDDSARFMEYETDLTFVGVVGMLD
PPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDL
PLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIG
GYVGAATVGAAAWWFMYADDGPGVTYSQLTHFMQCNEENPNFEGVDCEIFEAPEPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRA
LDFTQWLMVLKISFPVIGLDEVLKFIARNYLEDPEDERRK
NT seq
3003 nt
NT seq
+upstream
nt +downstream
nt
atggaggctgcacactccaagaccacagaagaatgtttggcctattttggggtgagcgag
actacaggccttagcccggaccaagtgaagcggcatctggagaaatatggccccaatgag
ctccctgctgaggaagggaagaccctgtgggagttggtgatagagcagtttgaagacctc
ctggtgcggatccttctcctggccgcctgcatttccttcgtgctggcctggttcgaggaa
ggcgaagagaccatcactgcctttgtggaaccctttgtcatcctcttgatcctcatcgcc
aacgccattgtaggggtttggcaggagcgaaatgcagagaatgccatcgaggctctgaag
gaatatgaacccgagatgggaaaagtgtaccgggctgaccgcaagtcagtgcaaaggatc
aaggctcgggacattgtccctggagacattgtggaggtggctgtgggggacaaagtccct
gcagatatccgcatcctgtccatcaagtccaccaccctccgggtggaccagtccatcctg
acaggcgagtccgtgtccgtcatcaaacacacagaccccgtccctgacccccgagctgtc
aaccaggataagaagaacatgcttttctcgggtaccaacattgctgctggcaaggcctta
ggcatcgtggccaccactggtgtgagcactgagatcgggaagatccgagaccaaatggca
gccacagaacaggataagacccctctgcagcagaagctcgatgagtttggggagcaactt
tccaaggtcatctcccttatctgtgtggccgtttggctcatcaacatcggccacttcaat
gaccccgtccacgggggctcctggatccgtggggccatctactactttaaaattgctgtg
gccttggctgtggccgcaatcccagaaggccttcctgcagtcattaccacctgtctggcc
ctgggcacccggcggatggcaaagaaaaatgccatcgtgaggagcttgccctctgtagag
actctgggctgcacttctgtcatctgttctgacaagacgggcaccctcaccaccaaccag
atgtctgtctgcaagatgtttatcattgacaaggtggatggaaacctctgtgtcctgaac
gagttcgctatcactggttccacttacgctccagaaggagaggtcttgaagaatgataag
ccagtccggtcagggcagtatgatgggctggtggagctggccaccatttgtgccctctgc
aatgactccgccttggacttcaatgagaccaaaggtgtttatgagaaggtgggtgaggcc
accgagactgcactcaccaccctggtggagaagatgaatgtattcaacactgacgtgaga
aacctctcaaaggtggagagggccaatgcctgcaactcggtgatccgccagctaatgaag
aaggaatttaccctggagttctcccgggacagaaagtccatgtctgtctattgctcccca
gccaaatcccgggctgctgtgggcaacaagatgtttgttaagggcgcccctgagggggtc
attgaccgctgtaactatgtgcgagttggcaccactcgagtgccgatgacggggccggtg
aaggacaagatcctgtcggtgatcaaggagtggggcactggccgggacacactgcgctgc
ctggccctggccacccgggacacccccccgaagcgagaggagatgattctggacgactct
gccaggttcatggaatatgagacggacctgacattcgttggtgtggtaggcatgctggat
ccaccacgaaaggaagtcaccggctctattcagctctgtcgggatgccggaatccgcgtc
atcatgatcactggcgacaataagggcacagccattgccatctgccggcggatcggcatc
ttcggggagaacgaggaggtggcggaccgagcctacacaggccgagagttcgacgacctg
cccctggcagagcagcgtgaggcctgccgtcgtgcctgctgcttcgcccgcgtggagcca
tcccacaagtcaaagattgtggagtacctgcagtcctacgatgagatcacagccatgaca
ggtgatggagtcaatgacgcccctgccctgaagaaggccgagatcggcattgccatggga
tctggcaccgccgtggccaagactgcttctgagatggtgctggccgatgacaacttctcc
accatcgtggctgcggtggaggaaggccgtgccatctacaacaacatgaagcagttcatc
cgctacctcatctcctccaatgtgggcgaggtggtctgcatcttcctgaccgccgccctg
gggctgcctgaggccctgatccctgtgcagctgctgtgggtgaacttggtgactgacggg
ctcccggccacggccctgggcttcaacccaccagatctagacatcatggaccgccccccc
cggagccccaaggagcccctcatcagtggctggctcttcttccgctacatggcaattggg
ggctatgtgggtgcagccactgtgggagctgctgcctggtggttcatgtatgcagatgac
gggcctggtgtcacctacagccagctgactcacttcatgcagtgcaatgaggaaaaccct
aattttgagggcgtggactgcgagatctttgaggcccctgagcccatgaccatggccttg
tccgtgctggtcaccatagaaatgtgcaacgctctcaacagcctgtctgagaaccagtcc
ctcctgcggatgcccccctgggtaaacatctggctgctgggctccatctgcctctccatg
tccctccacttcctcatcctctacgttgaccctctgccgatgatcttcaagctccgggcc
ctggacttcacccagtggcttatggtcctcaagatctcatttccagtcattgggctcgat
gaggtcctcaagttcattgctcggaactacctggaggatccagaagatgaaagaaggaag
taa
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