Canis lupus familiaris (dog): 480181
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Entry
480181 CDS
T01007
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04022
cGMP-PKG signaling pathway
cfa04024
cAMP signaling pathway
cfa04062
Chemokine signaling pathway
cfa04071
Sphingolipid signaling pathway
cfa04270
Vascular smooth muscle contraction
cfa04350
TGF-beta signaling pathway
cfa04360
Axon guidance
cfa04510
Focal adhesion
cfa04519
Cadherin signaling
cfa04520
Adherens junction
cfa04530
Tight junction
cfa04611
Platelet activation
cfa04670
Leukocyte transendothelial migration
cfa04810
Regulation of actin cytoskeleton
cfa04921
Oxytocin signaling pathway
cfa05135
Yersinia infection
cfa05163
Human cytomegalovirus infection
cfa05200
Pathways in cancer
cfa05205
Proteoglycans in cancer
cfa05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
480181 (ROCK1)
04071 Sphingolipid signaling pathway
480181 (ROCK1)
04024 cAMP signaling pathway
480181 (ROCK1)
04022 cGMP-PKG signaling pathway
480181 (ROCK1)
09133 Signaling molecules and interaction
04519 Cadherin signaling
480181 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
480181 (ROCK1)
04520 Adherens junction
480181 (ROCK1)
04530 Tight junction
480181 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
480181 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
480181 (ROCK1)
04670 Leukocyte transendothelial migration
480181 (ROCK1)
04062 Chemokine signaling pathway
480181 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
480181 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
480181 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
480181 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
480181 (ROCK1)
05206 MicroRNAs in cancer
480181 (ROCK1)
05205 Proteoglycans in cancer
480181 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
480181 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
480181 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
480181 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
cfa03036
]
480181 (ROCK1)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
480181 (ROCK1)
Protein kinases [BR:
cfa01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
480181 (ROCK1)
Chromosome and associated proteins [BR:
cfa03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
480181 (ROCK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
480181
NCBI-ProteinID:
XP_005623079
Ensembl:
ENSCAFG00000018282
VGNC:
45688
LinkDB
All DBs
Position
7
Genome browser
AA seq
1355 aa
AA seq
DB search
MSTGDSFEARFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVNQNSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVSQLESLNRELQERNRILENSKTQMD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDLLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEESNSMLTKDNELLRKENE
ELTDKMKRAEEEYKLKKEEEINNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHKNELQMQL
ASKESDIEQLRAKLLDLSDSTSIASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTSS
NT seq
4068 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgaggctcggtttgaaaaaatcgacaacctgctgcgggat
ccgaaatcagaagtgaattcggattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtcgaggtgcatttggagaagttcaattggtaaggcataaatccaccaggaag
gtatatgctatgaagcttctcagtaaatttgaaatgattaagagatctgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaatagcccttgggtcgtccagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggaatacatgcctggtggagat
cttgtaaatttaatgagcaactatgatgtgcctgaaaaatgggcacgattctatactgca
gaagtagtacttgcgttggatgcaatccattccatgggtttcattcatagagatgtgaag
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattac
atttcccctgaagtattaaaatctcaaggtggtgatggctattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctctggtaggaacttacagtaagattatgaaccataaaaattcacttactttccct
gatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattagggcgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gatcaatgggcttgggagacactccgagacactgtagcaccagttgtacctgatttaagt
agtgacattgatacaagtaattttgatgacttggaagaagataaaggagatgaagaaacg
tttcccatacctaaagcttttgttggcaatcagttaccctttgtaggatttacatattat
agcaatcgtagatacttatcttcagcaaatcctaatgataaccgaagtagccccaatgtg
gataaaagcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacagctgcat
aatgaaatgcaattaaaagatgaaatggagcagaaatgcagaacttcaaacataaaacta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaacctagaatctaca
gtgtctcagattgagaaggagaaaatgttgctacagcatagaattaatgagtaccagaga
aaagcagaacaggaaaatgagaaaagaaggaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaaaaaagtaaatcagaattcacagcttgctaatgagaaactt
gcacaattacaaaaacagctagaagaagccaatgacttacttaggacagaatcagacaca
gctgtaagattaaggaagagccacacagaaatgagtaagtcagttagtcagctagaatct
ctgaacagagaattgcaagagagaaacagaattttagagaattccaagacacagatggac
aaggactattaccagctgcaggctgtattagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagctcgaattacatccttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggagggagaaaggaaagaagctcaggacttgcttaat
cactcggaaaaggaaaagaataatttagagatagatttaaactataagcttaaatcatta
caacaacggctagaacaagaggtgaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcaatctattgaagaagcaaagtctgttgcaatgtgtgaaatggaaaaaaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaaacag
tgttcaatgctggatgttgatctgaaacaatctcagcagaagctcgaacatttgactgag
aataaagaaaggatggaggatgaagttaagaatctatccctgcagctggagcaggaatca
aataagcgactattgttacagaatgaattgaagactcaagcatttgaagcagacaattta
aaaggtctagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgaattagctcagcttacaaaacagtatagaggaaatgaaggacagatgcgg
gagctacaagatcagcttgaagctgagcagtatttctcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaaaatttaaagaaaatacaagag
ctacaaaatgaaaaagaaactcttgctactcagttggatctggcagaaacaaaagctgag
tctgagcagttggctcgagggcttctggaagaacagtattttgaattaacccaagaaagc
aagaaagctgcttccagaaataggcaagagattacagataaagatcacactgttagtcgg
cttgaagaatcgaacagcatgttaaccaaagataatgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaagagggcagaggaagaatataaattgaagaaggaggaggag
atcaataatcttaaggctgcctttgaaaagaatatcaatacagagagaacccttaaaacg
caggctgttaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaacacacaggatttgagaaagaaagaaaaggaaaatcgaaagctccaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtggtgaagcatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacgcataagaatgagcttcagatgcaatta
gctagcaaagagagtgatattgagcaactgcgtgccaaacttttggacctttccgattct
acaagtattgctagttttcctagtgctgatgaaactgatggaaaccttccagagtcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattttgttctataatgatgaacaagataaggaa
caatccaatccatccatggtattggacatagataaattgtttcatgttcgacctgtaacc
caaggagatgtttacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacaacaagctgaaaag
actaattttcaaaaccacaaaggccatgagttcattcctacactctaccacttccctgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccacctcctgccctagaa
tgtcgaagatgccatgttaagtgccacagagatcacttagataagaaagaggatttaatt
tctccatgtaaagtaagttacgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaacacatttggtaaagaagatccctaagaatcca
ccatctggttttgttcgtgcatcgcctcgaacgctttctacaagatctactgcaaatcag
tctttccgaaaggtggtcaaaaatacatctggaaaaactagcagttaa
DBGET
integrated database retrieval system
