KEGG   Canis lupus familiaris (dog): 480361
Entry
480361            CDS       T01007                                 
Symbol
EIF2S1
Name
(RefSeq) eukaryotic translation initiation factor 2 subunit 1
  KO
K03237  translation initiation factor 2 subunit 1
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04137  Mitophagy - animal
cfa04140  Autophagy - animal
cfa04141  Protein processing in endoplasmic reticulum
cfa04210  Apoptosis
cfa04932  Non-alcoholic fatty liver disease
cfa05010  Alzheimer disease
cfa05012  Parkinson disease
cfa05014  Amyotrophic lateral sclerosis
cfa05020  Prion disease
cfa05022  Pathways of neurodegeneration - multiple diseases
cfa05160  Hepatitis C
cfa05162  Measles
cfa05164  Influenza A
cfa05168  Herpes simplex virus 1 infection
cfa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    480361 (EIF2S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    480361 (EIF2S1)
   04137 Mitophagy - animal
    480361 (EIF2S1)
  09143 Cell growth and death
   04210 Apoptosis
    480361 (EIF2S1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    480361 (EIF2S1)
   05164 Influenza A
    480361 (EIF2S1)
   05162 Measles
    480361 (EIF2S1)
   05168 Herpes simplex virus 1 infection
    480361 (EIF2S1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    480361 (EIF2S1)
   05012 Parkinson disease
    480361 (EIF2S1)
   05014 Amyotrophic lateral sclerosis
    480361 (EIF2S1)
   05020 Prion disease
    480361 (EIF2S1)
   05022 Pathways of neurodegeneration - multiple diseases
    480361 (EIF2S1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    480361 (EIF2S1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    480361 (EIF2S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:cfa03012]
    480361 (EIF2S1)
   04131 Membrane trafficking [BR:cfa04131]
    480361 (EIF2S1)
Translation factors [BR:cfa03012]
 Eukaryotic type
  Initiation factors
   eIF-2
    480361 (EIF2S1)
Membrane trafficking [BR:cfa04131]
 Autophagy
  ER-phagy
   ER stress-related proteins
    480361 (EIF2S1)
SSDB
Motif
Pfam: EIF_2_alpha S1
Other DBs
NCBI-GeneID: 480361
NCBI-ProteinID: XP_005623592
Ensembl: ENSCAFG00000016386
VGNC: 40266
UniProt: A0A8C0RLY3 A0A8I3MV19
LinkDB
Position
8:41045920..41062790
AA seq 315 aa
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN
KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE
YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNI
NRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTT
TLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEV
DGDDDAEEMEAKAED
NT seq 948 nt   +upstreamnt  +downstreamnt
atgccgggtctaagttgtagattttatcaacacaaatttcctgaagtggaagatgtagtg
atggtgaatgtaaggtccattgctgaaatgggggcttatgtcagcttgctggaatacaac
aatattgaaggcatgattcttcttagtgagttgtccagaaggcgtatccgttctataaac
aaactcatcagaattggcaggaatgaatgtgtggttgtcattagagtggacaaagaaaaa
ggatatattgatttgtcaaaaagaagggtttctccagaggaagcaatcaaatgtgaagat
aaattcaccaaatccaaaactgtttacagcattcttcgtcatgttgctgaggtgttagag
tacaccaaggatgagcagctggagagcctgttccagaggactgcctgggtctttgatgac
aaatacaagagacctggatacggtgcctatgatgcatttaagcatgcagtctcagaccca
tctattttggatagtttagatctgaatgaagatgaacgggaagtacttattaacaatatt
aataggcgtttgacaccacaagctgtcaaaattcgagcagatatcgaagtggcttgttac
ggttatgaaggcattgatgccgtaaaagaagccctgagagcgggtttgaattgttctaca
gaaaccatgcccatcaagattaatctaatagctcctcctcggtatgtgatgactacaaca
accctggagagaacagaaggcctctctgttctcaatcaagctatggctgttataaaagaa
aagattgaggaaaagaggggtgtcttcaatgttcaaatggagcctaaagtggtcacagat
acagatgagaccgaacttgcaaggcagcttgagaggcttgagagagagaatgcagaagtg
gatggagatgatgatgcagaagaaatggaagccaaagccgaagattaa

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