Canis lupus familiaris (dog): 480580
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Entry
480580 CDS
T01007
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X3
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01521
EGFR tyrosine kinase inhibitor resistance
cfa01522
Endocrine resistance
cfa04012
ErbB signaling pathway
cfa04066
HIF-1 signaling pathway
cfa04140
Autophagy - animal
cfa04150
mTOR signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa04152
AMPK signaling pathway
cfa04211
Longevity regulating pathway
cfa04213
Longevity regulating pathway - multiple species
cfa04350
TGF-beta signaling pathway
cfa04371
Apelin signaling pathway
cfa04666
Fc gamma R-mediated phagosome formation
cfa04714
Thermogenesis
cfa04910
Insulin signaling pathway
cfa04931
Insulin resistance
cfa05163
Human cytomegalovirus infection
cfa05165
Human papillomavirus infection
cfa05170
Human immunodeficiency virus 1 infection
cfa05200
Pathways in cancer
cfa05205
Proteoglycans in cancer
cfa05207
Chemical carcinogenesis - receptor activation
cfa05210
Colorectal cancer
cfa05212
Pancreatic cancer
cfa05221
Acute myeloid leukemia
cfa05224
Breast cancer
cfa05225
Hepatocellular carcinoma
cfa05226
Gastric cancer
cfa05231
Choline metabolism in cancer
cfa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
480580 (RPS6KB1)
04350 TGF-beta signaling pathway
480580 (RPS6KB1)
04371 Apelin signaling pathway
480580 (RPS6KB1)
04066 HIF-1 signaling pathway
480580 (RPS6KB1)
04151 PI3K-Akt signaling pathway
480580 (RPS6KB1)
04152 AMPK signaling pathway
480580 (RPS6KB1)
04150 mTOR signaling pathway
480580 (RPS6KB1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
480580 (RPS6KB1)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagosome formation
480580 (RPS6KB1)
09152 Endocrine system
04910 Insulin signaling pathway
480580 (RPS6KB1)
09149 Aging
04211 Longevity regulating pathway
480580 (RPS6KB1)
04213 Longevity regulating pathway - multiple species
480580 (RPS6KB1)
09159 Environmental adaptation
04714 Thermogenesis
480580 (RPS6KB1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
480580 (RPS6KB1)
05205 Proteoglycans in cancer
480580 (RPS6KB1)
05207 Chemical carcinogenesis - receptor activation
480580 (RPS6KB1)
05231 Choline metabolism in cancer
480580 (RPS6KB1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
480580 (RPS6KB1)
09162 Cancer: specific types
05210 Colorectal cancer
480580 (RPS6KB1)
05212 Pancreatic cancer
480580 (RPS6KB1)
05225 Hepatocellular carcinoma
480580 (RPS6KB1)
05226 Gastric cancer
480580 (RPS6KB1)
05221 Acute myeloid leukemia
480580 (RPS6KB1)
05224 Breast cancer
480580 (RPS6KB1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
480580 (RPS6KB1)
05163 Human cytomegalovirus infection
480580 (RPS6KB1)
05165 Human papillomavirus infection
480580 (RPS6KB1)
09167 Endocrine and metabolic disease
04931 Insulin resistance
480580 (RPS6KB1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
480580 (RPS6KB1)
01522 Endocrine resistance
480580 (RPS6KB1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
480580 (RPS6KB1)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
480580 (RPS6KB1)
Protein kinases [BR:
cfa01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
480580 (RPS6KB1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
DUF1015
Motif
Other DBs
NCBI-GeneID:
480580
NCBI-ProteinID:
XP_005624809
Ensembl:
ENSCAFG00000017679
VGNC:
45744
LinkDB
All DBs
Position
9
Genome browser
AA seq
472 aa
AA seq
DB search
MDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTG
ANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILE
YLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVK
LTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPF
TGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFR
HINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTY
VAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVE
YPMETSGVEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
atggaccatgggggagttggaccatatgaacttggcatggaacattgtgagaagtttgaa
atttcggaaactagtgtgaacagagggccagaaaaaatcagaccagaatgttttgagcta
cttcgggtacttggtaaagggggctatggaaaggtttttcaagtacgaaaagtaacagga
gcaaatactgggaaaatatttgccatgaaggtgcttaaaaaggcaatgatagtaagaaat
gctaaagatacagctcatacaaaagcagaacggaatattctggaggaagtaaagcatccc
ttcattgtggatttaatttatgcctttcagaccggtggaaaactctacctcatccttgag
tatctcagcggaggagaattatttatgcagttagaaagagagggaatatttatggaagac
acagcctgcttttacttggcagaaatctccatggctttggggcatttacatcaaaagggg
atcatctacagagacctgaagccggagaatatcatgcttaatcaccaaggtcatgtgaaa
ctaacagactttggactatgcaaagaatctattcatgatggaacggtcacacacacattt
tgtggaacaatagaatacatggcccctgagatcttgatgagaagcggccacaatcgtgct
gtggattggtggagtttgggagcattaatgtatgacatgctgactggagcacctccgttt
actggggagaatagaaagaaaacaattgacaaaatcctcaaatgtaaactcaatttgcct
ccctacctcacacaagaagccagagatctgcttaaaaagctgctgaaaagaaatgctgct
tctcggcttggagctggtcctggagatgctggagaagttcaagctcatccattcttcagg
catattaactgggaagaactgctggctcggaaggtggagccaccctttaaacctctgttg
caatctgaagaggatgtgagtcagtttgattcaaagtttacacgtcagacacctgttgac
agcccagatgactcaactctcagtgaaagtgccaaccaggtctttttgggttttacatat
gtggctccatctgtacttgaaagtgtgaaagaaaaattttcctttgaaccaaaaatccga
tcacctcgaagatttattggcagcccacgaacacctgtcagcccggtcaaattttctcct
ggggatttctggggaagaggtgcttcagccagcacagcaaatcctcagacacctgtggaa
tatccaatggaaacaagtggagtagagcagatggatgtgacaatgagtggggaagcttca
gcaccacttccaatacgacagccgaactccgggccatacaaaaaacaagcttttcccatg
atctccaaacgaccagagcacctacgtatgaatctatga
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