Canis lupus familiaris (dog): 480688 Help Entry 480688            CDS       T01007                                  Symbol TSC1 Name (RefSeq) hamartin isoform X1   KO K07206   tuberous sclerosis 1 Organism cfa  Canis lupus familiaris (dog) Pathway cfa04072   Phospholipase D signaling pathway cfa04140   Autophagy - animal cfa04150   mTOR signaling pathway cfa04151   PI3K-Akt signaling pathway cfa04152   AMPK signaling pathway cfa04211   Longevity regulating pathway cfa04218   Cellular senescence cfa04714   Thermogenesis cfa04910   Insulin signaling pathway cfa05163   Human cytomegalovirus infection cfa05165   Human papillomavirus infection cfa05168   Herpes simplex virus 1 infection cfa05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:cfa00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     480688 (TSC1)    04151 PI3K-Akt signaling pathway     480688 (TSC1)    04152 AMPK signaling pathway     480688 (TSC1)    04150 mTOR signaling pathway     480688 (TSC1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     480688 (TSC1)   09143 Cell growth and death    04218 Cellular senescence     480688 (TSC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     480688 (TSC1)   09149 Aging    04211 Longevity regulating pathway     480688 (TSC1)   09159 Environmental adaptation    04714 Thermogenesis     480688 (TSC1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     480688 (TSC1)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     480688 (TSC1)    05163 Human cytomegalovirus infection     480688 (TSC1)    05165 Human papillomavirus infection     480688 (TSC1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hamartin Motif Other DBs NCBI-GeneID:  480688 NCBI-ProteinID:  XP_022279361 Ensembl:  ENSCAFG00000019882 VGNC:  47890 UniProt:  A0A8C0NVV6 LinkDB All DBs Position 9:50673940..50724548 Genome browser AA seq 1168 aa AA seqDB search MAQQANIGELLSMLDSPVLSVRDDVTAVFKENLSSDRGPMLVNTLVDYYLETNSQPVLHI LTTLQEPHDKHLLDKMNDCMGRAASRLPALSLLGHVIRLQPPWKHKLSQAPLLPSLLKCL KMDTDVIVLTTGVLVLITMLPMIPQSGKQHLHDFFDIFGRLSSWCLKKPGHVTEIYLVHL HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLDTFEEVVRPMMEHVRIHPELVTGSKDH ELDPRRWKRLETHDVVIECAKISLDPAEASYEDGDSISPQVSARFPHRAADVATSPYVDT QNSCGSATSTPYSSSRLTLLNTPGQPPQTLSPPSTRLLTEPPQATLWSPSMVCGMTTPPT SPGNVPPDLSHPYSKVFGTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLQQATVPAPKK EEKTDSARPCLHRQHHLPNDRGLEELPGLKGSVTLSDLPGFLGDLASDEDSVEKDKEEAA ISKELSEITTADTEPLVPRGGFDSPFYPDSLPGCPRKTHSATSGPQGTSVNPEPFNSSLD KRGPDTPKQAFTPIDLPCGGTHESPAGDRERQTSLETNILTPSPCKIPPQRGVGFGSGQP PPYDHLFEVALPKTAHHFVSKKTKELLKKAKGNTEEDYPPSTSPAEVLDRLIQQGADAHS KELSRLSLPSKSVDWTHFGGSPPSDEIRTLRNQLLLLHNQLLYERFKRQQHALRNRRLLR KVIKAAALEEHNAAMKDQLKLQEKDIQIWKVSLQKEQARYSQLQDQRDTMVTQLHSQIRQ LQHDREEFYNQSQELQTKLEDCRNMIAELRLELKKANSKVCHTELLLSQVSQKLSNSESV QQQMEFLNRQLLVLGEVNELYLEQLQSKHSDTTKEVEMMKAACRKELEKNRSHVLQQNQR LDTSQKRILELESHLAKKDHLLLEQKKYLEDVKVQARGQLQAAESRYEAQKRITQVFELE ILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLACCKDGCSDSVTDHHEEASGHNGETKPP RPGGARGSSGSRGGGGGSSGGSSSELSTPEKPPNQRAGLFSSRWETTVGEPATSIPTTVG SLPSSKSFLGMKARELFRNKSESQCDEDSVTISSLSETLKTELGKDLGVEAKTPPTLDGP HPTSPNPDSVGQLHIMDYNETHHEHSEG NT seq 3507 nt NT seq  +upstreamnt  +downstreamnt atggcccagcaagcgaatatcggggagctcctctccatgctggactcccctgtgctgagt gtgcgcgacgatgtgacagctgtcttcaaagagaacctcagctctgaccgtggtccgatg cttgtaaacaccttggtggattattacctggaaaccaattctcagccggtattacacatc ctgactaccttgcaagagcctcacgacaagcacctcttggacaaaatgaatgactgtatg ggcagagcggcctctcggctgcccgcgctgtcgttattggggcacgtcatcaggctgcag ccgccttggaagcacaaactctctcaagcacctcttttgccttctttactcaaatgtctc aagatggacaccgacgtcattgtcctcacaacaggtgtcttagtgttgataaccatgcta ccaatgattccacaatcggggaagcagcaccttcatgatttctttgatatttttggccgt ctttcgtcgtggtgcctgaagaaaccaggccatgtgacagaaatctatcttgtccatctc catgccagtgtttatgctctctttcatcgcctctacggaatgtacccttgcaactttgtc tcctttctacgctctcactacagtatgaaggagaacttggacacttttgaagaagtggtc aggccaatgatggagcatgtgcgaattcacccggaattagtgactggatccaaggaccac gaactggaccctcgaaggtggaagagattagaaacacatgatgttgtaatagagtgtgcc aaaatctctctggaccccgcagaagcctcatacgaagatggcgactccatatccccgcag gtgtcagcgcgctttcctcatcgtgcggctgatgtggccaccagcccttatgttgacacg caaaacagctgtgggagtgctacctcgaccccttattccagctctcggctgacgttgcta aatacgcccgggcagccacctcagactctgagtcccccgtcgacacggctgttgactgag ccgccacaagctactctttggagcccatctatggtttgtggtatgaccactcctccaact tctcctggaaatgtcccacctgatctctcacacccttacagtaaagtctttggtacagct ggtggaaaaggaactcctctgggaaccccagcaacttctcctcctccagccccattgtgc cactcggatgactatgtgcacatttccctccagcaggccacagtcccagctcccaagaag gaagagaaaacagattcagcaaggccctgtctacacagacagcaccatcttccaaacgac agaggattagaagagctacctggcctcaaaggttctgtcactctaagtgatcttccaggg tttttaggggaccttgcctctgatgaagatagcgttgaaaaagacaaagaagaagcggcg atatcaaaagagctctcagagatcacgacggctgacactgagcccctggttcctcgagga ggctttgactctcccttctacccggacagtctcccgggctgtcctcgcaagacccattca gccacctctggtcctcagggtaccagtgtgaatcctgaacctttcaactcctccttggac aagcgtgggccagacacaccaaagcaagcctttactcccatagacctgccctgtggaggc acccacgaaagccctgccggggacagggagcgccagacttcgctggagaccaacatcctc actcccagcccttgtaaaattccacctcagaggggagtggggtttggaagtgggcagcct cccccttacgatcatctttttgaggtggcattgccaaagaccgcccatcattttgtcagc aagaagaccaaggaactgttaaagaaagcaaaaggaaacacagaggaagactacccgccc tcaacctccccagcagaagttctggataggctgatccagcagggagccgacgcgcacagc aaggagctgagtcggttgtctttacccagcaagtctgtcgactggacccactttggaggc tctcctccctcagatgagatccgaaccctccgtaaccagttgcttttactgcacaaccag ttactctatgagcgttttaagaggcagcagcatgctctccgaaacaggcggctcctccgc aaggtgatcaaggcggcagctctggaggagcacaatgctgctatgaaagaccagttgaag ttacaggagaaggacatccagatctggaaggttagtctacagaaggaacaagcccggtac agccagctgcaggatcagcgagacacgatggtcacccagctccatagccagatccgacag ctgcagcatgaccgggaggagttctataaccagagccaggagctgcagacgaagctggag gactgcaggaacatgatcgcagagctgcgtctggaattgaagaaggccaacagcaaggtg tgtcacaccgagctgctgctcagtcaggtgtcccagaagctctcaaacagcgagtcggtc cagcagcagatggagttcttgaatcggcagctcttggtcctgggggaggtcaacgagctg tatctggagcaactgcagagcaagcactcggataccacgaaggaggtagagatgatgaaa gctgcgtgtcggaaagaattagagaaaaacagaagccacgttctccagcagaatcagagg ctcgatacctctcagaaacggattttggaactggaatctcacttggccaagaaagaccac cttcttttggagcagaagaaatatttagaggacgtcaaagtccaggcaagaggacagctg caggcggcagagagcaggtacgaggctcagaaaaggatcacccaagtgtttgaattggag atcttagatttatacggcaggttggagaaggatgggctcctgaagaaacttgaagaagaa aaagcagaagcagctgaagcagcagaagaaaggcttgcctgttgtaaggatggctgctca gattctgtaacagaccaccatgaagaggcatctggccacaacggcgagaccaagcccccc aggcctggtggtgcacggggcagcagtggaagtagagggggtggaggtggcagcagtggc ggcagcagcagcgagctttcaaccccagagaaaccccccaaccagagggcaggcctgttc agcagtcggtgggaaacgaccgtgggagagcctgccaccagcattcccactactgtcggc tcccttcccagttcaaaaagcttcctaggcatgaaggcacgagagttatttcgtaataag agtgagagccagtgtgatgaggacagtgtgaccatcagtagcctttctgagacgctaaag acagaactgggcaaagacctgggtgtggaagccaagactcccccaacccttgatggccca caccccacctccccgaacccagacagtgttggacagctccacatcatggactacaatgag actcatcatgaacacagtgaaggatga

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