Canis lupus familiaris (dog): 480691
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Entry
480691 CDS
T01007
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
480691 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
cfa03021
]
480691 (SETX)
Enzymes [BR:
cfa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
480691 (SETX)
5.6.2.5 RNA 5'-3' helicase
480691 (SETX)
Transcription machinery [BR:
cfa03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
480691 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
nSTAND3
ResIII
SLFN-g3_helicase
Helicase_RecD
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
480691
NCBI-ProteinID:
XP_005625254
Ensembl:
ENSCAFG00000019897
VGNC:
46062
UniProt:
A0A8P0P8A4
LinkDB
All DBs
Position
9:51164800..51245022
Genome browser
AA seq
2700 aa
AA seq
DB search
MLQKRCRMSTCCWCTPGGISTVDFLQRYASKIYSSEFQTADEDLCYCLECVTEYHKARDE
LPFLHEVLWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVP
LLEILKYPYLLLHERVSELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAIL
TARNLGKVDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTN
YKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQADDDSVDPFWPALHCF
MVILDRLGSKVWGQRIDPIEAFQTIINNVSYNREIQNIRNSSVRTKLEPESYSDDMVTCS
QIVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIP
FVQSLMDLKDLGMAYIVEVIHHLHSEVKDVLNQTDAICDKVTEFFLLILVSVIELHRNKK
CLHLLWISSQQWVEAVVKCAKLPTTAFTRNSEKSSGNCSKGTAMISSLSLHSMPSNSVQL
ACVQLIRSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQACLKQIIK
NIKVKVPQCSNFVDLSPTCKSSPVSYNKEESEQIERKSKKDLFCLENSSPTFPKESIKAE
MYQMQENILIKASNTIEEDNEQNYIKDLKLEDLSAESCIKQSSKSLFTERAQDQVKISTE
KPKSVKENCTSRSVLQNFTSRNGPERACDRGIITHLLTDSSTDSLEKMSTSNEDFSFKDD
VLGKTSKTKIKSQKDEICAKLSHVIKKQHRKSTFIDNIGNLEENLTVSNVDNFYSRKESG
DQKGDSFMHSLSLDPNGILDDKNGEQKSHKSLLLKKKQLKSEEFDIFSYHENSYQIQECH
TDDKDLVSFTEMTNTFVKKTSPFKDPVTVTVLESRDKEISKSTSPVSSHLRERIPGLSPQ
SDTLTDSQIDRDLHKLSLIAQASVIKFPSDSTQKSSSQLRRKVKDRCFLADQNNTGEACW
GQVIIISDSDDDDDDDEEEEEEGILGFEKPIKQDKIGIKKEYLKQHTSIASTNVEKKLMK
EEETLLQFEESDSQFFEFESPCEVFSVWQDQEPDKNSVQEGEKNSRSTDIADLMNDWGYE
TDYVSEEVIKKVAEGIEKHTEPQSSSVGEFCKIEVKKRKRKRFEKPVAEDPVRPSSSERN
EDQPDILNGRGLTENDLKNRDLRMASPSSSARRDKNTTVSLKKSSPKLRTYSKPIRRVPL
SKTPKKTHSDTKKGQSKNSNYISCRTTPAVVPPKKFRQCPEPTSTVEKLGLKKAPRRAFE
LSQRSLDYLVQLRDHGKTVGVVDTRKKTKLISPQTLSVRNNKKLLTSQDLQFRRQMRPKS
QQNKKGLLDYESKETTRAGPRPAQNSDILVPESDSSDYSSKGGTEVVANNTGKQLIKCVS
SEPEPIKTKCASRVTDDTCLLNQCASVVLNGRIPTNEVIVSPSADPLAGGDPTIHHLELA
TLKEGEPEYNSDTEDENIFLTQHHPEDMDLCSQMENGNEKLIEIVHRRDTAQVEEDSVGQ
PQLASWSSTKCKYKDCVETPENQGEYCSKHCEAKAADEDVFRKPALPLSASKPSRPSTAK
IFSSSSTSRIAGLSKSLESSSGLPPALKNKSNGGQAILKAPQPVSLLSPKAVGEVKSLCN
VLHPQTPNNSNRQGYKLTFGENKSFSASSPVNILLSSQSISDTFVKEILKWKYEMFVNFD
QCGPPASLCQSISRPVPVRFQDCGDYFNVFFPLMILNTFETVAQEWISSPNKEKFYQLHL
RKFPADYKKYWEFVVHLEECELAKQLHPKENDLVFLISERQNGEKKDTERNRMQDLREYH
CGYVHKFRRTSVMRNGKSECFLYIQTQDNLPVNLNEFVKCVVISSLVTTQRKLKAMSLLS
GRNQLARAVLNPNPMDFCTKDLLTTTSERIVAYLRDFNEDQKKAIETAYAMVKHSPSVAK
ICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELM
KKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHV
QEMHRRKEFLDRQLDELSRQRALCRGGREIQRQELDEKIAKVSKERQELASKIKEVQGRP
QKTQSIIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIH
RCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFYKLLEDNVEHNMIGRLPVLQLTVQ
YRMHPDICLFPSNYVYNRSLKTNRQTETNRCSSDWPFQPYLVFDVGDGSERRDNDSYVNV
QEIKLVMEIIKLIKDKRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDGF
QGRQKDCVIVTCVRANAMQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHL
IQDAQKRGAIIKTCDKNYRHDAAKILKLKPVLQRSLTHPPAIAPEASRPQDGLLSGKLDS
EFAKTSFTSSLYHTASDSKESAGTVTTKDPERPPIQDRLRDPRLLRRLGMDPEARGTCLR
EPQPLSPQHLGATPPSGEPGFPMSHQDPGGVPQATTQGATPNNHRPHVQGEPPAAGTDVP
TSKRKGDWEAGLSHRRESRAFSEGDQESWSPNSKHSRRNLDWDRRGLEKDDSGSKKRKLL
NT seq
8103 nt
NT seq
+upstream
nt +downstream
nt
atgcttcaaaagaggtgcagaatgagcacatgttgttggtgtacgccaggtggcatttcc
accgttgacttcctgcagcggtatgcatccaagatctactccagtgagtttcaaacagct
gatgaagacctctgctactgcttagagtgtgtgactgaataccacaaagcaagggatgag
ctgccattcttgcatgaggttttatgggaattagaaaccttacgtctcataaatcacttt
gaaaaatccatgaaggcagaaattggagacgatgatgaattgtatatagtagacaataat
ggagaggcacagctgtttgactttactggccaagactttgaaaataagcttcgagttcct
cttcttgaaatactgaaatatccttatctgcttttacatgagcgtgttagtgaactgtgt
gttgaagcactttgtcggatggaacaagctaattgctcctttcaggtttttgacaaacat
ccaggcatctatctgtttttggtccatcccaatgaaatggttcggcgttgggctatcctc
actgccagaaatttgggaaaagtggacagagatgattattatgacttgcaggaggttttg
acttgcctttttaaagtcatcgagttggggcttttggaaagtccagacatttatacttct
tctgtccttgagaagggtaaactgattcttctgccctcacacatgtatgataccaccaac
tacaaaaactattggttaggtatttgcatgttgctgaccattctggaggagcaggccatg
gactcactgttgctgggctcagacaaacagaatgattttatgcaatcaatacttcacacc
atggagaggcaagcagatgatgatagtgtggatcctttctggccagcgttacactgtttc
atggtgattctggatcgccttggatctaaggtctggggtcaacgtattgatcctattgag
gcatttcaaaccattatcaacaatgtaagctacaatagagagatccaaaatatacggaac
agctctgtaaggaccaagttagagccggagtcatattcggatgatatggtgacttgcagc
cagattgtatacaactataatcctgaaaagaccaaaaaggattcagggtggagatcagcc
atttgcccagattattgtcctaacatgtatgaagagatggaaacattagccagtgtgctt
caatcagatattggtcaagacatgcgtgttcataacagcacgtttctgtggttcatccct
tttgttcagtccctaatggatcttaaggatttgggtatggcttacatagtagaggttatt
catcatctgcactccgaagtcaaagatgtcctcaaccaaacagatgccatatgtgacaaa
gttactgaattttttcttctgattttggtgtctgtgattgagctgcatagaaataaaaaa
tgtttgcatttgctgtggattagttcccagcagtgggtagaagctgttgtaaaatgtgcc
aagcttcctactacggcattcacaaggaattctgagaaatcatctggaaattgctccaag
ggaacagcaatgatctcatctctgtctttgcattcaatgccgtcaaattctgtacagctg
gcttgtgtgcagctgattagaagtctccttaaagaaggttatcagcttgggcagcaaact
ctatgtaagcgattctgggataagctcaacttatttctgcgtggaaatttatctctaggt
tggcagttgactactcaggagacccatgaattacaagcttgtttaaagcaaattattaaa
aacattaaagtcaaagtacctcaatgtagcaattttgtggatctgagtcctacatgtaaa
agctctcctgtatcttacaataaagaagaaagtgaacaaatagagaggaagtctaaaaaa
gaccttttctgtctggaaaactccagtccaacatttcctaaagaatcaattaaagctgag
atgtatcaaatgcaagagaacatactgattaaagcaagtaacaccatagaagaggataat
gaacaaaattacataaaagatttgaagctagaagatctctcagccgagtcatgcataaag
cagagtagtaaaagccttttcactgaaagagctcaagatcaagttaaaataagtacagag
aagccgaagtctgtgaaagagaattgtacttcaagaagtgtactgcagaattttacttca
agaaatggtccagaaagggcatgtgacagaggaataataacacatttgttgaccgattcc
agcaccgattctctagagaagatgtccacatcaaatgaggatttctctttcaaggatgat
gttcttggcaaaacctcaaaaacaaaaattaagtcacagaaagatgaaatctgtgctaag
ttatcacacgtaataaagaagcaacacaggaaaagtacttttatcgataatattggtaat
ttagaggaaaacctgactgtatctaatgttgacaatttctattcaaggaaagagtcaggc
gatcagaaaggggatagcttcatgcacagtctctctttagaccctaatggcattctagat
gataaaaatggggaacaaaaatctcataagagtctattgctgaaaaagaaacagttaaag
agtgaagagtttgatatcttctcttaccatgaaaacagctatcaaatacaggaatgtcat
actgatgataaagatttggtctcatttacagaaatgaccaatacttttgtgaagaaaact
tctcccttcaaagatcctgtgactgtgactgttcttgagtcaagagataaggaaattagc
aagagtaccagtccggtatcttctcacttgagagaacgcattcctggcctcagtcctcag
tctgacaccttaacagattctcagatagacagagacctccacaagttatctttaatagct
caagccagcgttattaagttcccatcagattcaactcaaaaaagctcctcccagctacga
agaaaagtaaaagacagatgtttcctggccgaccagaataatactggggaagcctgttgg
ggccaggttatcattatttcagattctgatgatgatgatgatgatgatgaagaagaagaa
gaagaaggaattctgggttttgagaaacctataaaacaagataaaataggcatcaagaaa
gaatatctgaagcagcatacttcaatagctagtacgaatgtggaaaagaagctaatgaag
gaagaggagacccttctgcagtttgaggaatcagattctcagttttttgagtttgaaagt
ccatgtgaagtgttttcagtttggcaagatcaggaacccgacaagaattcagttcaagag
ggtgaaaaaaattcacgttcgactgacatagctgatctcatgaatgattggggttatgag
acagattatgtatctgaagaggttattaagaaagtagcagagggcattgaaaaacataca
gaaccacagagtagttctgttggggaattttgtaaaattgaagtaaaaaaacgtaagaga
aaacgatttgagaaacctgtggctgaagatcctgtacggccttcatcatctgagagaaat
gaggaccagcctgatattcttaatgggagaggtctgactgaaaatgatttaaaaaatagg
gacctgaggatggcaagtcccagttcaagtgctcgtagagacaaaaacactacagtttca
ctaaagaagtcttctccaaagcttcgtacttattccaaacccattaggagagtcccactt
tctaaaactcccaagaagacacattcagataccaaaaaaggacagagtaaaaattctaat
tacataagttgtagaacaactcctgctgtagttccaccgaagaaatttcgccagtgccct
gaaccaacttcgacagttgagaaacttggcctgaaaaaggctcctcgtagggcatttgag
ttgtcccagcgatctctagattatttagttcaattacgtgaccacggcaaaactgttgga
gtggttgatactagaaaaaagacaaagttaatttctcctcagactctctctgtcagaaac
aataagaaactgctgaccagtcaggatcttcagtttcgaaggcagatgagacccaaatca
caacaaaataaaaaaggacttttggattatgaaagtaaagagactacaagagcaggtcct
cgtccagcacagaattctgacatacttgtcccagaatccgatagctcagattatagttct
aaaggaggaactgaggtggttgctaacaacactgggaaacaattaataaaatgtgtgtct
tcggaaccagaacccataaaaacaaaatgtgcctctcgagtgactgatgatacttgtctt
ttgaaccagtgtgcctctgttgtgttaaatggaagaataccaacaaatgaagtcattgtc
tctccatcagcagaccccttagctggaggtgacccaacaatacatcatttagagttggca
actttgaaagagggagagcctgaatacaacagtgatacagaagatgagaatatatttcta
acccagcaccatcctgaagatatggatttatgttcacagatggagaatggtaatgagaaa
ctcattgaaatagttcatagaagagatacagctcaggtggaagaagattctgtaggtcag
cctcagttggcatcgtggagtagcacaaaatgtaagtacaaagattgtgttgaaaccccg
gaaaaccagggtgaatactgctcaaaacactgtgaagctaaagcagcagatgaagatgta
tttcgtaaacctgccttgcctctttctgcatctaagccttcgagaccttccactgctaag
atttttagctccagcagcacgtcacgaattgctggtctttccaagtctttggagagttcc
tcggggcttccaccagctctaaaaaataagtcaaatgggggacaggctattttgaaagcc
ccacagcctgtctctctattgtctccaaaggcagtgggtgaagtgaagagtctgtgcaat
gttcttcatcctcagactccaaataattccaacaggcaaggttacaaactgacatttggt
gaaaacaaatctttctcagcttcctctccagtaaacattctcttgtcatcacagtccatt
tctgacacctttgtcaaagagatcttaaaatggaagtacgaaatgttcgtcaactttgat
cagtgcgggcccccagcaagcctttgtcagtccatctcaagacctgtgcctgtcagattt
caagattgtggagattattttaatgttttcttccctttgatgatattgaatacttttgaa
accgtggcacaggagtggatcagctctccaaacaaagagaaattctatcagttgcattta
cgaaaatttcctgctgattataaaaaatattgggagtttgtggttcatcttgaagaatgt
gaactagccaaacagcttcatccaaaggaaaatgatttggtgtttttgatttctgaaaga
caaaatggagagaagaaagatacagagagaaatcgcatgcaggatctccgtgaatatcat
tgcggttatgttcataagtttcgccgcacttcagtcatgcgcaacgggaagtctgagtgt
ttcctttacatccagactcaagataatttgccagtcaatttaaatgaattcgtgaaatgt
gttgtaatcagttctctggtaactacgcaaaggaagttgaaagccatgtctctgttgagt
ggacggaaccaactggccagagctgttcttaatccaaatcccatggacttctgtacaaaa
gatttactaactacaacgtctgagagaattgtcgcctacttaagagatttcaatgaagac
caaaagaaagcaatagaaactgcatatgccatggtcaaacactccccgtcagttgccaag
atctgtctgattcatggaccaccaggaacagggaaatcaaaaactattgttggcctcctg
taccgcctcctgacagagaaccagaggaaagggcattcagatgaaaactccaatgccaaa
atcaaacaaaaccgtgtccttgtgtgtgcaccttccaacgcagctgttgatgaacttatg
aaaaaaatcatccttgaatttaaagaaaaatgtaaagacaagaagaatcctttgggaaac
tgtggagatataaatttagttcgtctgggtccagaaaagtctattaataatgaagtccta
aaattcagtttggatagccaagttaaccacagaatgaaaaaagacttaccctctcatgtt
caggagatgcacagaagaaaggaatttctggatcgtcaacttgatgaactttcccgccaa
cgtgctttatgccgaggtggaagggaaatacagaggcaagaattagatgaaaaaattgcg
aaagtttcaaaagagaggcaggaactagcttccaaaattaaggaggttcaaggacgccca
caaaaaacacagagcatcatcatcttagagtcccatgttatctgctgcacattgagcacg
agtggtggtttactgcttgagtctgcttttcgtgggcaagggggtgtccccttcagttgt
gtcattgtcgatgaggccggtcagtcttgtgaggttgagactctgactccgctcatccat
cgttgtaacaagctcatcctcgtaggagatcctaaacagctccctcccaccgtcatttct
atgaaagcacaggaatatggctatgaccaatcaatgatggcacgcttctacaagctgcta
gaagacaatgtggagcacaatatgatcggcaggctgcctgttttacagttgactgttcag
tacaggatgcatccagacatatgtctcttcccctctaattatgtttataacagaagcttg
aaaacaaatagacagactgaaaccaatcggtgttcatcagactggccatttcaaccttac
ctggtgtttgatgtcggagacggttcagaaagacgggataatgactcatatgtaaatgtt
caagaaataaaactggtaatggaaataattaaacttattaaagacaaaagaagggatgtt
actttccggaacattggcataataacccattacaaggctcagaagacgatgattcagaag
gatttggacaaagagtttgatagaaaagggccagcagaagtagataccgtggatgggttc
cagggccggcagaaggattgtgttattgttacatgtgtcagagcaaatgccatgcagggc
tcaattggatttctggcaagtttgcagagactgaatgtcaccatcacacgagccaagtac
agtctcttcatcctcggacatttaaggaccctgatggaaaatcagcactggaatcacctg
attcaggatgcacagaagcggggcgccatcatcaagacctgtgacaagaactataggcac
gatgcggcgaagattctgaagctgaagcctgtgctgcagagaagtctgactcaccctcct
gccatagccccggaggcatccagaccccaggatggcttgctcagcggcaagctagacagt
gagtttgccaagacctctttcacgtcttccctgtatcacacggcatctgactccaaggaa
tctgctgggactgtcactacaaaggaccccgaaaggcctcccattcaggaccgactgcgg
gacccacgactgcttcggaggttgggcatggaccccgaggccagagggacgtgcttgcgg
gagccgcagcccctgagcccccagcatcttggagcaacacctccctcaggagagccaggc
ttccccatgagtcaccaggacccagggggtgtgccccaggccaccacccaaggagccacg
ccaaacaaccacagacctcacgtgcagggcgagcctccagcggcgggcacagatgttccc
acaagtaagaggaaaggtgactgggaagcagggctgagccacagaagagagagcagggcc
ttcagtgaaggggaccaggagagctggagccccaacagcaagcactcgaggaggaacctg
gactgggacaggagagggctggagaaggatgacagtggctctaagaaaagaaagctttta
tag
DBGET
integrated database retrieval system
