Canis lupus familiaris (dog): 481624
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Entry
481624 CDS
T01007
Symbol
NANS
Name
(RefSeq) sialic acid synthase
KO
K05304
sialic acid synthase [EC:
2.5.1.56
2.5.1.57
2.5.1.132
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00541
Biosynthesis of various nucleotide sugars
cfa01100
Metabolic pathways
cfa01250
Biosynthesis of nucleotide sugars
Module
cfa_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00541 Biosynthesis of various nucleotide sugars
481624 (NANS)
Enzymes [BR:
cfa01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.56 N-acetylneuraminate synthase
481624 (NANS)
2.5.1.57 N-acylneuraminate-9-phosphate synthase
481624 (NANS)
2.5.1.132 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase
481624 (NANS)
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Gene cluster
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Motif
Pfam:
NeuB
SAF
DUF2458
Motif
Other DBs
NCBI-GeneID:
481624
NCBI-ProteinID:
XP_538746
Ensembl:
ENSCAFG00000002469
VGNC:
43615
UniProt:
A0A8C0RCF1
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Position
11:53719899..53744431
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AA seq
359 aa
AA seq
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MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLEVAKRMIRTAKECGADCAKFQKSELEY
KFNRKALERPYTSKHSWGKTYGEHKRHLEFSHEQYRELQRYAQEVGIFFTASGMDEMAVE
FLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFC
FLQCTSAYPLLPEDVNLRVITEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHIT
LDKTWKGSDHSASLEPGELAELVRSVRLVERAMGSPTKQLLPCEMACNEKLGKSVVAKVR
IPEGTVLTLDMLTVKVGEPKGYPPEDIFGLVGKKVLVTVEEDDTILEESVENHGKKIKS
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atgccgctggagctggagctgtgtcccgggcgctgggtgggcgggcagcacccgtgcttc
atcattgccgagatcggccagaaccaccagggcgacctggaagtggccaagcgcatgatc
cgcacggctaaggagtgtggggccgattgtgccaagttccagaagagcgagctggagtac
aagtttaatcggaaagccttggagaggccctatacgtccaagcattcctggggcaagacg
tacggggagcacaagcgccacctggagttcagccacgagcagtacagggagctgcagaga
tacgctcaggaggttggcatcttcttcacggcctcgggcatggatgagatggcagttgag
tttctgcatgagctgaatgttccgtttttcaaagttggatctggggacactaataatttt
ccttatctggaaaagacagccaaaaaaggccgcccaatggtgatctccagtggaatgcag
tcgatggacaccatgaagcaagtctatcagattgtgaagcctctcaaccccaacttctgc
ttcctccagtgcaccagtgcatacccgctcctccctgaggacgtcaacctgcgcgtcatc
acggaatatcagaagctctttcctgacattcccatagggtattctgggcatgaaacaggc
atagcgatatctgtggccgcagtggctctgggtgccaaggtgctggagcgtcacataact
ttggacaagacgtggaaggggagtgatcactcagcctcgctggagcccggagagctggct
gagctggtgcggtccgtgcgcctcgtggaaagggccatgggctccccgaccaagcagttg
ctgccttgtgagatggcctgcaacgagaagctgggcaagtccgtggtggccaaagtgagg
attccagaaggcactgttctaacattggacatgctcaccgtgaaggtgggtgagcccaaa
ggctaccctcctgaagacatctttggtctagtgggcaagaaggtcctggtcactgttgaa
gaagacgacaccatcttggaagaatcggtagaaaatcatggcaaaaaaatcaagtcttaa
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integrated database retrieval system