Canis lupus familiaris (dog): 481963
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Entry
481963 CDS
T01007
Symbol
REV3L
Name
(RefSeq) DNA polymerase zeta catalytic subunit isoform X1
KO
K02350
DNA polymerase zeta [EC:
2.7.7.7
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01524
Platinum drug resistance
cfa03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03460 Fanconi anemia pathway
481963 (REV3L)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
481963 (REV3L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
cfa03400
]
481963 (REV3L)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
481963 (REV3L)
DNA repair and recombination proteins [BR:
cfa03400
]
Eukaryotic type
TLS (translesion DNA synthesis) factors
B-family DNA polymerases
481963 (REV3L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DUF4683
DNA_pol_B
POL3_N
REV3_N
DNA_pol_B_exo1
zf-C4pol
Motif
Other DBs
NCBI-GeneID:
481963
NCBI-ProteinID:
XP_013973691
Ensembl:
ENSCAFG00000003942
VGNC:
45488
UniProt:
A0A8C0MFV9
LinkDB
All DBs
Position
12:complement(67596234..67773130)
Genome browser
AA seq
3137 aa
AA seq
DB search
MFSVRIVTADYYMASPLRGLDTCLCPLTQAPVKKVPVVRVFGATPAGQKTCLHLHGIFPY
LYVPYDGYGQQPESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKEK
HFMKIYLYNPAMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAV
KFRKARRKSNQLHTTGSCKDRLPGNSLTGTLFRWEEDEIPSSLILEGVEPQSTCELEVDA
VAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNETSQINQPESQDRRFVPATESEKN
FQKRLQEILKQNDFSVRTLSGSVDYSDGSQEFSAELTLHSEVLSPDTLQCTPANMVEVHK
DTELGKGHAVYKVEEALINEEAILNLMENSQTFQPLTQRLSESPVFLDSSPDEALVRLLA
GLENDGYQGGRNRMPSPCHFFGNTKNPQNSDDEENEPQIEKEEMELSLVMSQRWDSNIEE
PCAKKRSLCRNTRRSSTEEDDSSSEEEMEWSNNSLLLANLSIPQLDGTADENSDNPLNNE
NSRTHSSVIATSKLSVKPSIFHKDAATLEPPSSAKITFQCKHTSALSSHVLNKEDLIEDL
PQPNNIEKCIDHSVASFTNESTYSMKYPGSLSSSVHSENSHKESSKKDILPVSSCESSIF
DYEEDIPSVPRQVPSRKYTNIRKIDKDTPFIHMNRHSSENTLGKNSFNFSDLSHPKNKLP
SEGNEKGNSTALNSLFPSSLTENCELLSCSGENRTMVHSLDSIADESGLNKLKIRYEEFQ
EHKTEKPSLSQQAAHYMFFPSVVLSNCLSRPQKLSPVTYKLQPSSKQSRLKINKKKLIGH
QETSTKTSETVSTKDNCIQNNPCNSNPEKDNVLASDLIKVTRGAFENKTPIDSFIDCHFG
DGTLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHSMEIGESLDGTLK
SRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPL
KDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKTGKQQRTNSENIKRTLSFRRKR
SHAILSPPSPSYNAETEDCDLNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEMM
AAVDKETMLFKGPNACINKTANSRVEKNSRARAQVKKSKTKLVNPSVVTKKRNKRNQTNK
VGDDGKKKPRAKQKQKTNEKGMSRKHITIKDEKIKSQPGAEVKFVLKHQNVSETSNSSGG
SQLLFKQKDVSLMGSTIDHPLSAPLPTGIHAQQNLSGCFSSFLESKKPVDLQTFPSSRDD
LHSSVVCSSLGPGISKINVQRSHNQSAMFTLKESTLIQKNIFDLSNHLSQVAQNTQISSG
ITSPKTEENANTQKNYLSSIGKLNEYRNSLESKPDQAYAPNFLHCKDSQQQIVCGSEQSK
HNETCSPGNAAAEESQMPNNCFVTSLRSPIKQIAWEQKQRGFILDMSNFKPERVKQRSLS
EAISQTKALSQCKSRNVSTPSAFGEGQSGLAVLKELLQKRQQKAQNANIMQDPLSNKHQP
NKNISGSLEQNKTVKRTRSVTSSRKPRTPRSTKPKEKIPKLIKVDSLNLQNSVQLDNSLS
DDSPIFFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKF
LSDAVQDLFPGQAIEKNEFLSHDNQKCDEDKHHASDSTSWIRSSTLSPELFEKSSIDNNE
NHRHNQWKSSFHPLTTRSNSIMDSFCVQQAEDCLNEKSRLNRSSVSKEVFLSLSQPGTSD
WIQGHTRKEMQQSLDSVNTSFTTILSSPDGELVDAASEDLELYVSRNNDMLTPTPDSSPR
STSSPSQSKNGSFTPRTAHILKPLMSPPSREEIMATLLDHDLSETIYQEPFCSNPSDVPE
KPREIGGRLLMVETRLPNDLAEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRNGQAVVN
KGSSNSSKMAEDKKIVIMPCKCAPSRQLVQAWLQAKEEYERSKKLSKNEPTGVVKSAENF
SSSVNPDDKPVVPPKMSTTPHILPTTAHTKEDVDNSQFALQAVTTGCSQTVSESQTLPPV
ASADDPEKGEDDDDDDNDDYYVSYSSPDSPVIPPWQQATSPDSKILNGDERPISPVKELH
SLNIENFLKPVKDGIQKSPSSEPLEPLVISPINVRARTGICESLCLHSTPIVQRKFLERL
PEASSLSPLSTEPKTQKLSHKKGSNTDTFRRILLTQAKNQFAAVNTPKKETSQIDGPSLN
NTYGFKVSVQNLQEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICALFYCISSDTP
LPDTDKTELTGVIVIDKDKTVSSQDIRYQTPLLIRSGITGLEVTYAPDEKALFQEIADII
KRYDPDILLGYEIQMHSWGYLLQRAAALSVDLGQMISRVPDDKIENRFAPERDDYGSETM
SEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYR
WKMVDHYISRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKP
MNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTC
LGHVENLGKYDEFKFGCTSLRVPPDLLYQIRHDITVSPNGIAFVKPSVRKGVLPRMLEEI
LKTRLMVKQSMKAYKQDRALSRMLDARQLGLKLIANVTFGYTAANFSGRMPCIEVGDSIV
HKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNP
KPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERS
LKLLFETRDISLIKQYVQRQCMKLLEGKASIQDFIFAKEYRGSSSYKPGACVPALELTRK
MLTYDRRSEPRVGERVPYVIIYGTPGVPLIQLVRRPVEVLQDPTLRLNATYYITKQILPP
LARIFSLIGIDVFNWYHELPRIQKATSSSRSEPEGRKGTISQYFTTLHCPVCDDLTQHGI
CSKCRSQPQHVAVILNQEIRELERKQEQLVKICKNCTGCFDRHIPCVSLNCPVLFKLSRV
NRELSKAPYLRQLLDQF
NT seq
9414 nt
NT seq
+upstream
nt +downstream
nt
atgttttcagtgaggatagtgaccgccgactactacatggccagcccgctgcggggcctg
gacacctgcctgtgccccctcacccaggcccctgtcaagaaggtgccggtggtgcgagtc
ttcggagcgaccccggcaggtcagaagacatgtcttcatctgcatggcatctttccttac
ctctatgtgccatacgatggttatggacagcagccagaaagctatctttctcagatggca
ttcagtatcgacagagcacttaatgtggctttaggcaatccatcttccactgctcagcac
gtgttcaaagtgtcattagtatcaggaatgcctttttatggttatcatgagaaggaaaaa
cactttatgaagatctatctttacaatcctgcaatggtgaaaaggatatgtgaacttttg
caaagtggagccataatgaataaattttaccagcctcatgaagcgcatattccctacctc
ctacagctgttcattgactacaatctctatggaatgaatttaataaatctggctgctgtc
aagttccgaaaagcgagaaggaaaagtaatcagttgcatacaactggatcttgcaaggat
cggctaccaggaaattctcttactggtaccttatttcggtgggaagaagatgaaatacca
agctctttaatactggaaggtgttgaacctcagagtacatgtgaattagaagtggatgcc
gtagctgctgatatcttaaatcggctggatattgaagctcaaattggtgggaaccctgga
ctgcaggccatatgggaagatgaaaagcaacggcgaagaaaccgaaatgaaacctctcaa
attaaccaacctgaatcacaagatcgcaggtttgtgccagcaacagaaagtgaaaaaaat
tttcagaagagacttcaggaaattctcaaacagaatgatttctctgtcagaacattatca
ggatcagtggactacagcgatggatctcaggagttctctgctgagttaacactgcactct
gaagttctgtctcctgatactcttcagtgtacaccggctaatatggtagaagtccacaaa
gatacagagttgggcaaaggtcatgctgtgtacaaagtggaggaagctctcattaatgaa
gaagcaattttgaacctcatggaaaatagtcagacttttcagcctttgacccaaagactg
agtgagtcacctgttttcctggacagtagtcctgatgaggctctggtacgtcttcttgct
ggtttggaaaatgatggatatcaggggggaagaaataggatgccatcaccatgtcatttc
tttggaaacactaaaaatccccaaaatagtgatgatgaagaaaatgaaccacagattgaa
aaagaagaaatggagcttagtttggtgatgtctcagagatgggacagcaatattgaagaa
ccttgtgccaaaaagagatcactgtgtagaaatacccgtagaagctcaactgaagaagat
gattcatcctcagaagaagaaatggaatggagtaataacagtttgcttctggccaatctt
tctatacctcagttagatggaactgcagatgaaaatagtgacaatccattgaacaacgaa
aattctaggacccactcttctgtgattgcaacgagcaagctatcagtaaaaccttccatc
tttcacaaagatgctgctacattagaacccccatcttctgctaagattacctttcagtgt
aaacacacaagtgccctttcttcccatgttttgaacaaggaagatttaattgaagacctt
ccacagccaaacaacatagaaaaatgtatagatcattcagttgcttcttttacgaatgaa
agcacttactctatgaaataccctggatctttgagcagttctgtccattcagaaaactct
cataaagaaagtagtaagaaagatatcctcccagtatcttcctgtgaaagtagtattttt
gattacgaagaagatattccatctgttccaagacaagtaccaagtagaaagtatacgaat
attagaaaaattgataaggataccccttttatacacatgaaccgtcatagtagtgaaaat
acattgggcaaaaattctttcaacttttctgacctaagtcatccaaaaaataaattaccc
tctgaaggaaatgaaaaaggaaacagcacagctctgaatagtttattcccttcatcatta
actgaaaattgtgaattgctatcatgctcaggagagaatagaactatggtacattctctt
gatagcattgctgatgaaagtgggctaaataaacttaaaattagatatgaagagtttcag
gaacataaaacagaaaagccaagcctcagccagcaagcagcacattatatgttttttccc
agtgttgttctatctaactgtctgagtagaccacagaaactctctcctgtcacatacaaa
ctacaacccagcagtaaacagtcccggttaaaaattaataaaaagaagcttataggtcat
caagagacttctaccaaaactagtgagactgtatccacaaaagataattgtatacaaaat
aatccttgtaatagtaatcctgagaaggataatgtattggccagtgatttaattaaagtc
acccgcggagcttttgaaaataaaacacccatagacagttttatagactgtcactttgga
gatggaaccttagaaactgagcagtcctttggattgtatggaaataaatatacacttaga
gccaaacgcaaggtaaattatgagactgaagatagtgaatcaagttttgtaacacacaac
tcaaaaattagcctacctcattccatggaaattggtgaaagtttagatggaactctcaaa
tctcgaaaacgaagaaaaatgtctaaaaagctaccccctgtcatcataaagtatattatt
attaacagatttagagggagaaaaaatatgcttgtgaagctaggaaaaatagactctaaa
gaaaaacaagttatattgacagaggaaaaaatggaactgtataagaagcttgcacctttg
aaggatttttggccaaaagttcctgactctcctgcaaccaaatatcccatttatccacta
acaccaaagaaaagtcacagaagaaaatcaaaacataagtctgctaagaaaaaaactggt
aagcaacaaaggacaaatagtgaaaatattaaaagaactttgtcttttaggcgaaaacga
tcacatgctatcctgtctcctccctcaccatcttacaacgctgaaaccgaagactgtgac
ttgaattatagtgatgttatgtctaaactaggttttctttctgaaagaagcacaagtccc
ataaattcttctccccctcgctgctggtctcccacagatccaagagctgaagaaatgatg
gctgctgtagataaagaaacaatgctttttaagggtcctaatgcatgtattaacaagact
gctaattctcgtgtggaaaaaaatagtcgagcaagagcgcaggttaagaaatcgaaaact
aaacttgttaatccctctgtagttactaagaaaaggaacaaacgaaatcagacaaataaa
gtaggagatgatggaaaaaagaaaccgagagcaaaacagaaacaaaaaacaaatgagaaa
ggtatgtcaagaaagcatataacaattaaagatgaaaaaataaaatctcagcctggtgct
gaagttaagtttgtgctgaaacatcagaatgtgtctgagacctcaaatagttctggaggc
tctcaactacttttcaaacagaaagatgtgtcactaatgggctctactatagatcatccc
ctttctgctcccctgcccactggaattcatgcacaacagaatttgtctggctgcttttct
tcttttttagaaagcaagaagcctgtagatttgcaaacattccccagctcacgggatgat
ttgcattcatcagttgtttgtagttctttgggacctggaatctcaaaaattaatgttcag
aggtctcataatcaaagtgctatgtttactctaaaggaatcaaccttgattcaaaaaaat
atatttgatctttccaaccacttgtctcaggtagcacagaatacacagatatcttcgggt
ataacatctccaaagacagaagagaatgcaaatacacaaaaaaactatttgtcatctatc
ggaaagttaaatgaatatcgtaattctttagaatcaaagccagaccaggcatatgcccct
aattttttgcattgcaaagacagtcagcagcagattgtgtgcgggtcagaacagtcaaag
cacaacgaaacttgttctccaggaaatgcagctgcagaggaaagccaaatgcctaataat
tgctttgtaacttccttaagaagtccaatcaaacaaatagcatgggagcaaaaacaaagg
ggctttattttagatatgtcaaattttaaacctgaaagggtaaaacagaggtcgttgtca
gaagcaatttcacaaaccaaagcactttctcagtgtaaaagtcgaaatgtgtcaacacct
tcagcatttggtgaaggccagtctggactggcagttctaaaagaattgttacagaaaaga
cagcagaaagcacaaaatgcaaatattatgcaagacccattatctaataaacatcaacca
aacaaaaatatttctggttccctcgagcaaaacaaaacagttaaaagaacacgatcagta
acatcttcaagaaaacctcgaactccaagaagtacgaaacctaaagaaaaaattcccaaa
cttattaaagtagactctctaaatttacaaaactctgtccagttggataattctctatca
gatgatagtcccatctttttttcagatccaggttttgagagttgttattcacttgaagat
agcttgtctcctgaacataattataattttgatattaatacaataggtcaaactggattt
tgtagtttttattctggaagtcagtttgtcccagctgatcagaatttgcctcagaagttc
ctaagtgatgcagttcaggatcttttcccaggacaagctatagaaaaaaatgagttttta
agtcatgataaccagaagtgtgatgaagacaaacatcatgcctccgactcaacctcgtgg
attagatctagtactttaagtcctgaactatttgagaaatcatccatagataacaatgag
aatcatcgccataaccagtggaaaagtagctttcatcctctaacaactcgctctaattca
ataatggattctttctgtgtccagcaggcagaggattgtctaaatgaaaagtccagattg
aataggagttcagtaagcaaagaagtgtttcttagcctctcacagccaggtacttcagac
tggattcaaggtcataccagaaaagagatgcaacagtctcttgactcagtcaatacctct
tttactacaatactatcgtcccctgatggtgaacttgtggatgcagcctctgaagattta
gaattgtatgtgtccagaaacaatgatatgttaacaccaactcctgatagctccccaagg
tctaccagctctccctcacaatctaaaaacggcagtttcacccctcgaactgctcacatt
ctgaaaccacttatgtccccaccaagtagggaagaaattatggcaactttgttggatcat
gacctctcagaaactatttaccaggaaccattttgcagtaatccttcagatgtaccagaa
aagcccagggagatcggtggacggcttctcatggtagagactcgacttccaaatgatctg
gctgagtttgagggagacttttccttggaaggacttcgtctgtggaaaacagcattctca
gcaatgactcagaatccaagaccagggtcaccccttcgcaatggccaggcagtggtcaat
aaagggtcaagtaatagctctaaaatggctgaagataaaaaaattgtgattatgccttgc
aaatgtgccccaagtcgacaactggttcaagcatggcttcaagccaaagaagaatacgaa
cgttccaagaaactgtctaaaaatgagccaactggagttgtaaaatctgctgagaacttc
agctcttcagttaacccagatgacaaacctgtagtgcctccaaaaatgagtacaactcca
catatactccccactacagcacataccaaggaagatgttgataactctcagtttgcttta
caagccgtaaccacaggatgtagtcaaactgtaagtgaaagtcagacactgccaccagtt
gcttctgcagatgatcctgaaaaaggtgaagatgatgatgatgatgataatgacgactat
tatgttagttatagctcccctgattctccagtaattccaccttggcaacaagcaacatcc
ccagattccaaaatattaaatggagatgagagacccatatcaccagtaaaggaactgcat
tccctgaatattgagaacttcttaaaaccagtaaaagatggtatacagaaaagtccaagc
agtgagccactagagcctctagtgatatctccaattaatgttagggcaagaactggaata
tgtgaatcactttgccttcatagtacaccaattgtccagaggaaatttctggaaaggctt
cctgaagcaagtagcctgagccctttatcaacagaaccaaaaacccagaaattgagtcat
aagaaaggaagtaatactgacacttttagaagaatactcttaacacaagcaaagaatcaa
tttgcagcagtaaataccccaaagaaagaaacttctcagattgatggaccatctttaaac
aatacttatggtttcaaagtcagcgtacaaaacttacaggaggcaaaagctttacatgag
atacaaaatcttaccctaatcagtgtggagttacatgctcgaacgagacgagacttagaa
ccagatcctgaatttgaccccatctgtgctctgttttactgcatctcctctgacacccca
ctaccagatacagacaaaacagaactcacgggtgtaatagtaattgataaagacaagact
gtctccagccaagatatcaggtatcagaccccattgctgattagatctggaattacagga
ctagaagttacctatgcacccgatgagaaggcactttttcaagaaattgcagatataata
aagaggtatgatcctgatattttgctaggatatgaaattcagatgcattcctggggttac
ctcttacaaagggctgctgccttaagtgttgacttaggtcagatgatctctcgggtgcca
gatgacaaaattgagaatagatttgcacctgaaagagatgactatggatcagaaacaatg
agtgaaataaatattgttggccgaattacactaaatctttggagaatcatgagaaatgag
gtggctttaactaactacacctttgaaaatgtgagctttcatgttcttcatcagcgtttt
cccctctttacctttcgagtcttatcagattggtttgataacaagacagatctgtacaga
tggaaaatggttgatcactacattagccgtgtccgtggaaatctccaaatgttagaacag
ttggacctgattgggaaaaccagtgaaatggctagactctttggcatccagtttttacat
gtactgacaaggggttcacagtaccgtgtggaatcaatgatgttgcgtattgctaaacca
atgaactatattcctgtgacacctagtgtacagcaaagatcccaaatgagagccccacag
tgtgttcccctaattatggagcctgaatctcgcttctatagcaactctgttctcgttttg
gatttccagtcactatatccttcgattgtgattgcgtacaactactgtttttccacctgc
cttggccatgtggagaacctgggaaagtatgatgagttcaaatttggctgtacctctcta
agagtacctccagatttactttaccaaattaggcatgatatcacagtgtcccccaatgga
atagcttttgtcaagccttcagtaagaaagggtgtgctaccaagaatgcttgaagaaatt
ttgaagactagactcatggtgaaacagtcaatgaaggcttacaagcaagacagagccctt
tcacgaatgctcgatgcacgtcaactaggacttaagcttatagcaaatgtcacatttggc
tatacagctgcgaatttttctgggagaatgccatgcattgaggttggtgatagtattgtt
cacaaagccagagagaccttggagcgagctattaaactggtgaatgataccaagaaatgg
ggcgctagggttgtatatggagatactgacagtatgtttgtgctactgaaaggagccact
aaggagcagtcttttaagattggtcaggaaattgctgaagctgtaactgctaccaatcct
aaaccagtgaaattgaagtttgaaaaggtatatttgccctgtgtcttacaaacaaaaaag
aggtatgtgggttacatgtatgaaacactggatcaaaaggacccggtatttgatgcaaaa
ggaatagaaacagtcagaagagattcctgccctgctgtttctaagatacttgagcgttct
ctaaagctgctatttgaaacaagagatataagtttaattaaacagtatgttcagcgacaa
tgtatgaaacttctggaaggaaaagccagcatccaagattttatctttgccaaggaatac
agaggaagttcctcttataaacctggagcttgtgtgccagcccttgaacttacaaggaaa
atgcttacttacgatcggcgctctgagcctcgagttggagagcgagtgccatacgtcatc
atttatgggacccccggagtaccacttatccagctagtgaggcgcccagtggaagtgctg
caggacccgactctgagactgaatgccacttactacatcaccaagcaaatcctgccaccc
ctggcaagaatcttctcacttattggtattgatgtcttcaactggtatcatgaattacca
aggatccagaaagccaccagctcctctcgaagtgaacctgaagggcgaaaaggcactatt
tcacaatatttcactactttacactgtcccgtgtgtgatgacctaacccagcatggcatc
tgtagtaaatgtcggagccaacctcagcatgttgcagtcatccttaaccaagaaattcga
gagttggaacgtaaacaggaacaacttgtaaagatatgcaagaactgtacagggtgcttt
gaccgacatatcccgtgtgtttctctcaactgcccagtacttttcaaactctcccgagta
aatagagaattatccaaggcaccatatctccggcaattactagaccagttttaa
DBGET
integrated database retrieval system
