Canis lupus familiaris (dog): 483148
Help
Entry
483148 CDS
T01007
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2 isoform X1
KO
K20994
Notch 2
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01522
Endocrine resistance
cfa04330
Notch signaling pathway
cfa04658
Th1 and Th2 cell differentiation
cfa04919
Thyroid hormone signaling pathway
cfa05165
Human papillomavirus infection
cfa05200
Pathways in cancer
cfa05206
MicroRNAs in cancer
cfa05207
Chemical carcinogenesis - receptor activation
cfa05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
483148 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
483148 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
483148 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
483148 (NOTCH2)
05206 MicroRNAs in cancer
483148 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
483148 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
483148 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
483148 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
483148 (NOTCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
EGF
hEGF
EGF_CA
EGF_2
Ank_2
Ank
Notch
NOD
NODP
Ank_5
Ank_4
Ank_3
EGF_3
JAG1-like_EGF2
Elf-1_N
Motif
Other DBs
NCBI-GeneID:
483148
NCBI-ProteinID:
XP_005630745
Ensembl:
ENSCAFG00000010476
LinkDB
All DBs
Position
17:complement(56476088..56659161)
Genome browser
AA seq
2471 aa
AA seq
DB search
MPGLSPARLWALLALGLSCAAPARALQCRDSYEPCVNEGVCVTYHNGTGYCKCPEGFLGE
YCQHRDPCERNRCQNGGTCVAQAMLGKATCRCALGFTGDDCQYSTTHPCFVSHPCLNGGT
CHMHSRDDYECTCQVGFTGKLCQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
IDVNECDIPGQCQHGGTCLNLPGSYQCQCPQGFTGKHCDSPYVPCAPSPCVNGGTCRQTG
DFTFECNCLPGFEGITCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
ECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGFKGADCTEDVDECA
MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCVHGVCM
DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCLCPEGPHRPSCYSQ
VNECLSSPCIHGNCTGGPSGYKCLCDAGWIGINCEVDKNECLSNPCQNGGTCDNLVNGYR
CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDNISGYTCHCVLPYTGKNCQTVLAPCSPN
PCENAAVCKEAPDFESYTCLCAPGWQGQRCTIDIDECVSKPCMNHGLCHNTQGSYMCECP
PGFSGMDCEDDIDDCLANPCQNGGSCVDGVNTFSCLCHPGFIGDKCQTDMNECLSEPCKN
GGTCSDYVNSYTCKCQAGFDGVHCENNIDECTESSCFNGGTCVDGINSFSCLCPLGFTGP
FCLHEINECNSHPCLNEGICVDGLGTYRCTCPLGYTGKNCQTLVNLCSRSPCKNKGTCIQ
EKAESRCLCPSGWAGAYCDVPNVSCEVAALHRGVSTDHLCQHSGICINAGNSHHCQCPLG
YTGSYCEEQLDECSSNPCQHGATCRDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
TCVDLVNHFKCSCPPGTRGLLCEENIDDCVGGPHCLNGGQCVDRIGGYSCRCLPGFAGER
CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFIDVCPQMPCLNGGTCA
VASNMPDGFICRCPPGFSGAKCQSSCGQVKCRRGEQCVHTASGPRCFCPNPQDCESGCAS
SPCQHGGSCYPQRQPPYYSCQCSPPFWGSHCELYMAPTSTPPATCLSQYCADKARDGVCD
EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTAECLFDNFECQGNS
KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADRPENLAEGTLVIVVLMPPEQLLQ
DARSFLRALGTLLHTNLHIKRDSQGALMVYPYYGEKSAATKKQRMTRRSLPGDQEQEVAG
SKVFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLNPKPTQLLY
LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDSSNHKRREPVGQDAVGLKNL
SVQVSEANLIGSGTSEHWVDDEGPQPKKAKAEDEALLSEEDDAIDRRPWTQQHLEAADIR
RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDMSDEDEDGEDSSANIIT
DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
KKPRRPNTKSTMPTSLPNLAKEAKDAKGSRRKKSLSDKGQLSESSVTLSPVDSLESPHTY
VSDTTSSPMITSPGILQASPNPMLATAAPPAPAHAQHALSFSNLHEMQPLAHGASTVLPS
VSQLLSHHHIAPPGNGSAGSLGRLHPVTVSADWMNRMEMNETQYNEMFGMVLAPAESTHP
GIPPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGTPQPQSNCPPPVAGPMPTMY
QIPEMARLPSMAFPTAMVPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
EPPRSNMQVYA
NT seq
7416 nt
NT seq
+upstream
nt +downstream
nt
atgcccggcctgagccccgctcggctgtgggcgctgctggcgctcgggctgagctgcgcg
gcccccgcgcgcgcattgcagtgtcgggatagctatgagccctgtgtaaatgaaggagta
tgtgttacctaccacaatggcacaggatactgcaaatgtccagagggtttcttgggagaa
tattgtcaacatcgagacccctgtgagaggaaccgctgccagaatggtgggacgtgtgtg
gcccaggccatgttggggaaagcaacatgccgatgtgccctggggttcacaggtgatgat
tgccagtactcaaccactcatccctgctttgtttctcacccctgcttgaatggaggcacc
tgccacatgcatagccgggatgactatgagtgcacctgccaagttggttttacaggtaag
ctgtgccagtggactgatgcctgcctgtctcatccctgtgcgaatggaagtacctgtacc
actgtggccaaccagttctcctgcaaatgcctcacaggcttcaccggacagaagtgtgag
attgatgtcaatgagtgtgacattccaggacagtgccagcatggtggcacctgcctcaat
ctaccgggttcctatcagtgccagtgcccccagggcttcacaggcaagcactgtgacagc
ccctatgtgccctgtgcaccctccccctgtgttaatggtggcacctgccggcagactggt
gacttcacatttgaatgcaactgccttccaggttttgaagggatcacctgtgagcggaat
attgatgactgccctaaccacaagtgtcagaatggaggggtttgtgtggatggggttaat
acttacaactgccgctgtccccctcagtggacaggacagttctgcacagaggatgtggat
gagtgtctgctacaacctaatgcttgtcagaatggaggcacctgtaccaaccgcaatggg
ggttatggctgtgtatgtgttaatggctggagtggagatgactgcagtgagaacattgat
gactgtgcctttgcctcctgcaccccgggctccacctgcattgaccgtgtggcctccttc
tcttgcatgtgcccagaaggaaaggcaggtctattatgtcatctggatgatgcatgcatc
agcaatccttgccacaagggggcactgtgtgataccaaccccctgaacgggcagtatatt
tgcacctgccctcaaggcttcaaaggggctgattgtacagaagatgtggatgagtgtgct
atggccaatagcaatccttgtgagcatgcaggaaagtgtgtgaacacagatggtgccttc
cactgtgaatgtctgaagggctatgcagggcctcgttgtgagatggacatcaatgagtgt
cattccgacccctgccagaatgatgcaacctgtctggataagattggaggcttcacatgt
ttgtgcatgccaggtttcaaaggtgtacattgtgaattggagataaacgaatgtcagagc
aacccttgtgtgaacaatggtcagtgtgtggataaagtcaatcgcttccagtgtctatgt
ccacctggtttcactgggccagtttgccagattgatattgatgactgttccagtactcca
tgtctgaatggggcaaagtgtattgatcacccgaatggctatgaatgccagtgtgccaca
ggattcactggtgtgttgtgtgaggagaacattgacaactgtgaccctgatccttgccac
catggccagtgtcaggatgggattgattcctacacctgcatctgcaacccggggtacatg
ggtgccatctgcagtgaccagatagatgagtgttacagcagcccctgcctgaatgatggt
cgctgcattgacctggtgaatggctaccagtgcaactgccagcctggcacatcaggtgtt
aattgtgaaatcaattttgatgactgtgcaagtaacccttgtgtccatggggtctgtatg
gatggcattaatcgttacagttgtgtctgctcaccaggattcacaggacagagatgtaac
attgacattgatgagtgtgcctccaatccctgtcgcaagggtgcaacatgcatcaatgat
gtgaatggtttccgctgtctatgccctgagggtcctcatcgccccagctgctactcacag
gtgaacgagtgcctgagcagtccctgcatccatggaaactgtaccgggggccctagtgga
tacaagtgcctttgtgatgcaggctggattggtatcaactgcgaagtggacaagaatgaa
tgtctttctaacccatgccagaatggaggaacttgtgacaatctggtgaatggatacagg
tgtacttgcaagaagggctttaaaggctataactgtcaggtgaatattgatgaatgtgct
tcaaatccgtgtctgaaccaaggaacctgctttgataacataagtggctacacttgccac
tgtgtgctgccatacacaggcaagaattgtcagacggtattggctccctgttccccaaac
ccatgtgagaatgctgctgtttgcaaagaggcacccgattttgagagttacacctgcctg
tgtgcccctggctggcaaggtcagcggtgtacaattgacattgatgaatgtgtctccaaa
ccctgcatgaaccatggtctctgccataatacccagggcagctacatgtgcgagtgtcct
ccgggcttcagtggtatggactgtgaggacgacatcgatgactgtcttgccaatccttgc
cagaatggaggttcctgtgtagatggagtgaatactttctcctgcctgtgtcatcctggc
tttattggagataagtgtcaaacagacatgaatgagtgtctgagtgaaccctgtaagaat
ggagggacttgctctgactatgtcaacagttacacttgcaagtgccaggcgggatttgat
ggagtacactgtgagaacaacatcgacgagtgcactgagagctcctgtttcaatggtggc
acatgtgtcgacgggattaactccttctcttgcttgtgccctttgggctttactggcccc
ttctgcctccatgagatcaatgaatgcaactctcacccatgcctaaatgaaggaatatgt
gttgatggccttggtacctaccgctgcacctgtcccttaggctacactgggaaaaactgt
cagacactggtgaacctctgtagtcggtctccatgtaaaaacaaaggtacttgcattcag
gaaaaagcagagtcccggtgcctgtgtccatcaggatgggctggtgcttactgtgacgtg
cccaatgtgtcctgtgaggtggcggccttacacagaggggtgtccactgaccacctgtgc
cagcactccggcatctgcatcaatgctggcaactcgcatcactgccagtgccccctgggc
tacactgggagctactgtgaggagcagctcgatgagtgctcatccaacccctgccagcat
ggggccacctgcagggacttcattggcgggtacagatgtgagtgtgtcccaggatatcag
ggcgtcaattgcgagtatgaagtagatgagtgtcagaatcagccatgccagaacggaggc
acctgtgtcgacctcgtgaaccatttcaagtgctcctgtccaccaggcactcgaggcctg
ctttgtgaagagaacattgatgactgtgttgggggtccccactgcctcaatggtggtcag
tgtgtggataggattgggggctacagttgtcgctgcttgcctggctttgcgggagagcgg
tgtgagggcgacatcaacgagtgcctctcgaacccctgcagctctgagggcagcctggac
tgcatccagctaaccaatgactacctgtgtgtctgtcgcagtgccttcactggtcgtcac
tgtgaaactttcatcgatgtgtgtccccagatgccttgtctgaatggggggacgtgtgct
gtggccagcaacatgcctgatggtttcatttgtcgttgtcccccgggattctccggagcg
aaatgtcagagcagctgtggacaagtgaagtgcaggagaggagagcagtgtgtgcacacg
gcctcaggaccacgctgcttctgccccaacccccaggactgtgaatcaggctgtgccagt
agtccctgccaacacgggggtagctgctatcctcagcgccagcctccttactactcttgc
cagtgttctccaccattctggggtagccattgtgaactttacatggctcccaccagcacc
cctcctgccacctgcctgagccagtattgtgccgacaaagctcgggacggcgtctgcgat
gaggcctgcaacagccatgcctgccagtgggatgggggtgactgttccctgaccatggag
aacccctgggccaactgctcttccccactcccctgctgggattacatcaacaaccagtgt
gatgagctgtgcaacacagcggagtgcctttttgacaattttgaatgccaggggaacagc
aagacatgcaagtatgacaaatactgtgcagaccacttcaaagacaaccactgtgaccag
ggatgcaacagtgaggagtgtggctgggatgggctggactgtgctgctgaccggccagag
aacctggcagaggggaccctggttatagtggtgctcatgcccccagagcaactgctccag
gatgcccgcagcttcttgcgggcactgggcaccctgctccataccaacctgcacattaaa
cgggactcccagggggcactcatggtctacccctattatggtgagaagtcagctgccaca
aagaagcagaggatgactcgcagatcccttcccggtgatcaagaacaagaggtggctggc
tctaaggtatttctggaaattgacaaccgccagtgtgttcaagattcagaccaatgtttc
aagaacacagatgcagcagcagctcttctggcttctcacgccatccaagggaccttgtcc
taccctcttgtatctgttgtcagtgaatctctgaatccaaaacccactcagcttctttat
ctacttgctgtcgctgtcgtcattatcctatttattatcctgctgggagttatcatggcc
aaaagaaaacgtaagcatggctccctctggctgcctgaaggtttcacccttcgccgagac
tccagcaatcacaagcgtcgtgaaccagtgggacaagatgccgtggggctgaaaaatctc
tcagtgcaagtctcagaggctaacctaattggttctggaacaagtgaacattgggttgat
gatgaagggccccagccaaagaaagccaaggctgaagatgaagctttgctctcagaagaa
gatgatgccattgatcgacgtccatggacacagcagcaccttgaggctgcagatatccgc
aggacaccatcactggcactcactcctccacaggcagagcaggaggtggacgtgctggat
gtgaatgtccgtggcccagatgggtgcaccccattgatgctggcttctctccgaggaggc
agctcagatatgagtgatgaagatgaagacggagaagactcttctgccaacatcatcaca
gacttggtctaccagggtgccagcctgcaggcccagacagaccggactggtgagatggcc
ctgcaccttgcagcccgctactccagggctgatgctgccaagcgtctcttggatgcaggt
gcagatgccaatgcacaggacaacatgggccgttgccctctccatgctgcagtggcagct
gatgcccagggggtcttccagattctgatccgcaaccgagtaactgatttggatgccagg
atgaacgacggcactacaccgctgatcctggctgcccgcctagctgtggagggaatggtg
gcagaactaatcaactgccaagcagatgtgaatgcagtggatgaccatgggaaatctgct
cttcactgggcagctgctgtcaataacgtggaggcaacccttttgctgttgaaaaatggg
gccaaccgagacatgcaagacaacaaggaagagacacctctgtttcttgctgcccgggag
ggaagctatgaagcagccaagatcctgttagaccattttgccaatcgggacatcacagac
catatggatcgtcttccccgggatgtggctcgggaccgcatgcaccatgacatcgtgcgc
ctcctggatgagtacaatgtgacgccaagccctccaggcactgtgctgacttctgcactc
tcacctgtcatctgtgggcccaacagatctttcctcagcctaaagcatacccccatgggc
aagaagcctagacggcccaataccaagagtaccatgcctaccagcctccctaaccttgcc
aaggaggccaaggatgccaagggtagtaggaggaagaagtctctgagtgacaagggtcag
ctgtctgagagctcagtgaccttatcccccgttgattccttagagtctcctcacacatat
gtttctgacaccacatcctctccaatgatcacatcccctggaatcttacaggcctcaccc
aaccctatgttggccaccgctgccccccctgccccagcccatgctcagcatgcactgtcc
ttctctaacctgcatgaaatgcagccgttggctcatggtgccagcactgtgcttccctca
gttagccagctgctgtcccaccaccacattgctcccccaggcaacggcagtgcagggagc
ttgggtaggctccatcctgtcactgtttcggcagattggatgaaccgcatggagatgaat
gagacccagtacaatgagatgtttggtatggttctggctccagctgagagcacgcatcct
ggcatacctccccagagcaggccgcctgaagggaagcacataactacccctcgggaacct
ttgccccccattgtgactttccagctaatccccaaaggcagtattgcccaaccagcaggg
actccccagcctcagtctaactgccctccacctgttgcaggccctatgcccaccatgtat
cagattccagaaatggctcgtttgcccagtatggctttccccactgccatggtgccgcag
caggatgggcaggttgctcagaccattctcccagcctatcatccttttccggcatctgtg
ggcaagtatcccacaccaccttcacagcatagttatgcttcctcaaatgctgctgagcga
acacctagtcacagtggtcacctccagggtgagcatccctacctgacaccatccccagag
tctcctgaccagtggtcaagttcatcaccccactctgcttctgactggtcagatgtgacc
accagccctacccctgggggtgctggaggaggtcagcggggacctggaacacacatgtct
gagccaccacgcagcaacatgcaggtttatgcatga
DBGET
integrated database retrieval system
