Canis lupus familiaris (dog): 484073
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Entry
484073 CDS
T01007
Symbol
PDE10A
Name
(RefSeq) LOW QUALITY PROTEIN: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00230
Purine metabolism
cfa01100
Metabolic pathways
cfa04024
cAMP signaling pathway
cfa05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
484073 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
484073 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
484073 (PDE10A)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
484073 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
484073 (PDE10A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
484073
NCBI-ProteinID:
XP_541190
Ensembl:
ENSCAFG00000000795
VGNC:
44345
UniProt:
A0A8C0MYK1
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Position
1:complement(54243884..54542326)
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AA seq
1071 aa
AA seq
DB search
MASPAEPRAPRPQAPLPAAGDEPGSGPGPGKLRPEPWRGAAGGGGAVGPGPAPERPGGGP
AERAAPPPPRPPPSSAGRASPAGGPGALSARGGGGGGGGGGGWGPARAPFALALSSPVPS
SSPSSFYFWPPPPPPPPSLLPSSSAFHLPVRLPGREGAAAAAAAAGGGGGDAGGGGGQEA
APLSVPPGSSPRGGGGGGGGRRRLFLCSALQSLLLPARAGLRLPLGPAARRAGSPGFPGA
GGGCPGPSPGGGGRTPRRPRGAGFALAAASPLLFGSDMEDGPSNNASCFRRLTECFLSPS
LTDEKVKAYLSLHPQVLDEFVSESVSTETVEKWLKRKNNKPEDESAPKEVSRYQDTNMQG
VVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCVFTPPGIK
EGKPRLIPAGPIAQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPI
VTAIGDLIGILELYRHWGKEAFCMSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFL
LDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGK
PIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIV
SRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTME
KLSYHSICTAEEWQGLMRFNLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCF
ELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHGLFTDLERKGLLIACLCH
DLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVL
EIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWP
VTQLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQ
IFPPTEPLLKACRNNLSQWEKVIRGEESAVWISSPPGAHGPSEKLPVKIDD
NT seq
3216 nt
NT seq
+upstream
nt +downstream
nt
atggccagccccgcagagccgcgcgctccccgcccccaggcccccctgccagcggccggg
gacgagcccggctccggccccggccccggcaaactccgcccggagccctggcgcggcgct
gccggcggggggggcgcggtgggcccggggccggccccggagcggcctggcggcggcccg
gccgagcgcgccgcgcccccgcccccgcgcccgcccccctcgtccgcaggccgcgccagc
cccgcggggggcccgggcgccctgagtgcgcgcggcggcggcggcggcggcggcggcggc
ggcggctggggcccggcccgcgctcccttcgcgctcgccctctcctcccctgtcccctcc
tcctctccatcttccttttacttctggccgccgccccctccgccccctccctctcttctc
ccctcctcatctgcctttcacctccccgtgcgtctcccaggaagggagggcgcagcggcg
gcggcggcggcggctggaggaggcggcggcgatgctggcggcggcggaggacaagaggca
gctcccctgagcgtccctcccggcagtagtccccgcggcggcggcggcggcggcggcggg
cggcggcggctcttcctctgctccgcgctccagagcctgctgctcccggcccgcgccggg
ctccggctcccgctcggcccggccgcccgccgcgcgggctcccccggcttcccgggcgcg
ggcgggggctgccccggccccagcccaggcggcggcggccgaactccgcggcggccccgg
ggcgccggcttcgccctcgccgccgcgtcccccctgctcttcggctccgacatggaagat
ggaccttctaataacgcgagctgcttccgaaggctgacggagtgtttcctgagccccagt
ttgacagatgaaaaagtgaaggcatatctttctcttcatccccaggtgttagacgagttt
gtatctgaaagtgttagtacagagacagtagaaaaatggctgaagaggaaaaacaacaaa
ccagaagatgaatcggctcctaaggaagtcagccggtaccaagacacgaatatgcaggga
gttgtgtatgaactaaacagctatatagaacaacggttggatacaggaggagacaaccag
ctactcctctatgaattgagtagcatcattaaaatagccacaaaagctgatggatttgca
ctgtatttccttggagagtgcaataatagtctgtgcgtgttcactccacctggaatcaaa
gaaggaaagccccggctcattcctgctgggcctattgcccagggcaccaccatctctgcc
tatgtggccaagtccagaaaaacattgctagtggaagacatccttggggatgaacggttt
ccaaggggtactggtctggagtccgggactcgcatccagtctgttctttgtttaccaatt
gtcactgcaattggtgatttgattggtatcttggagctctaccggcactggggcaaagaa
gctttctgtatgagtcaccaggaggttgcaacagcaaatcttgcctgggcttcagtagca
atacatcaggtgcaggtgtgcagaggccttgcgaaacaaactgagctgaatgacttccta
ctggatgtgtccaagacgtattttgataacatagttgcaatagactctctacttgaacac
ataatgatatatgcaaaaaatctggtgaatgccgatcgttgtgcacttttccaggtggac
cataagaacaaggagttatattcagacctttttgatattggagaggaaaaggaaggcaaa
cctatcttcaagaagaccaaagaaataagattttcaattgagaaaggaattgctggtcag
gtagcaagaacaggggaagtcctgaacattccagatgcctatgcagacccacgctttaac
agagaagtagacttgtatacagggtacaccacacggaatattctgtgcatgcccatcgtg
agtcgaggaagtgtgatcggcgtggtacagatggtgaacaaaataagcggcagtgccttc
tctaaaacggatgaaaacaacttcaagatgtttgccgtcttttgtgcgttagccttacac
tgtgccaatatgtaccacagaatccgtcactctgagtgcatttaccgggtgaccatggag
aagctgtcctaccatagcatctgtactgcggaggagtggcagggcctcatgcgcttcaac
ctccctgtgcgcctctgcaaagaaattgaattattccactttgatattggtccttttgaa
aacatgtggcctggaatttttgtctacatggtccatcgttcctgtgggacgtcttgcttt
gagcttgaaaagttgtgtcgttttattatgtctgtgaagaaaaactatcggcgggttcct
tatcacaactggaaacacgcagtcaccgtagcgcactgcatgtatgccatcctccagaac
aaccacgggctcttcactgacttggagcgcaaaggactgctaatcgcgtgtctgtgtcat
gacctggaccacaggggcttcagtaacagctacctgcagaaattcgatcaccctctggca
gctctctattccacctctaccatggagcagcaccacttctcccagacagtgtccatactc
cagttggaagggcacaatatcttctccaccctgagctccagtgaatatgaacaggtgctt
gagatcatccgcaaagccatcattgccacagaccttgctttatactttggaaacaggaaa
cagttggaagagatgtaccagaccggatcgctaaaccttaataatcaatcacatagagat
cgtgtcattggtttgatgatgactgcctgtgatctttgttctgtaacaaaactatggccg
gtgacacaattgacggcaaatgacatatatgcagaattctgggctgagggtgatgaaatg
aagaagttgggaattcagcctatccccatgatggacagagacaagaaggacgaagtccca
caaggccagctgggcttctacaacgctgtggccatcccctgctataccaccctcacccag
atcttcccgcccacagagcctctcctcaaagcatgcaggaataacctcagccagtgggag
aaggtgatccgaggggaggagagcgcagtgtggatctcatcgccgccaggggcccatggg
ccctcggagaagctgcctgtgaagatcgatgactga
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