Canis lupus familiaris (dog): 484196
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Entry
484196 CDS
T01007
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
KO
K05855
spleen tyrosine kinase [EC:
2.7.10.2
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04064
NF-kappa B signaling pathway
cfa04072
Phospholipase D signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa04380
Osteoclast differentiation
cfa04611
Platelet activation
cfa04613
Neutrophil extracellular trap formation
cfa04625
C-type lectin receptor signaling pathway
cfa04650
Natural killer cell mediated cytotoxicity
cfa04662
B cell receptor signaling pathway
cfa04664
Fc epsilon RI signaling pathway
cfa04666
Fc gamma R-mediated phagocytosis
cfa05152
Tuberculosis
cfa05167
Kaposi sarcoma-associated herpesvirus infection
cfa05168
Herpes simplex virus 1 infection
cfa05169
Epstein-Barr virus infection
cfa05171
Coronavirus disease - COVID-19
cfa05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
484196 (SYK)
04072 Phospholipase D signaling pathway
484196 (SYK)
04151 PI3K-Akt signaling pathway
484196 (SYK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
484196 (SYK)
04613 Neutrophil extracellular trap formation
484196 (SYK)
04650 Natural killer cell mediated cytotoxicity
484196 (SYK)
04662 B cell receptor signaling pathway
484196 (SYK)
04664 Fc epsilon RI signaling pathway
484196 (SYK)
04666 Fc gamma R-mediated phagocytosis
484196 (SYK)
09158 Development and regeneration
04380 Osteoclast differentiation
484196 (SYK)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
484196 (SYK)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
484196 (SYK)
05167 Kaposi sarcoma-associated herpesvirus infection
484196 (SYK)
05169 Epstein-Barr virus infection
484196 (SYK)
09171 Infectious disease: bacterial
05152 Tuberculosis
484196 (SYK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
484196 (SYK)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
484196 (SYK)
Protein kinases [BR:
cfa01001
]
Non-receptor tyrosine kinases
SYK family
484196 (SYK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
Kdo
DUF7063
ABC1
SH2_1
Motif
Other DBs
NCBI-GeneID:
484196
NCBI-ProteinID:
XP_038460677
Ensembl:
ENSCAFG00000002171
VGNC:
47021
LinkDB
All DBs
Position
1:complement(96356719..96440184)
Genome browser
AA seq
633 aa
AA seq
DB search
MAGSTADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA
HHYTIEREMNGTYAIAGGRTHGSPAELCHYHSQESDGLVCLLKQPFHRPPGVQPKTGPFE
DLKESLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRVESEQI
VMIGSKTNGKFLIRDRNDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGGQPGNINFGARAPLPGAHPATWSAGGIISRIKSYTFPK
PGHRKAASSTGSRPESSFNPYEPDRGPWATDRDAQREALPMDTEVYESPYADPEEIRPKE
VYLDRKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEAN
VMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGM
KYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE
CINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPAGCPREMY
ELMKLCWTYEVDRRPGFEAVELRLRNYYYDVVN
NT seq
1902 nt
NT seq
+upstream
nt +downstream
nt
atggcgggaagcacggccgacagcgccaaccacctgccgttcttcttcggcaacatcacc
cgggaggaagcggaggactacctggtccagggcggcatgagcgatgggctgtacctgctg
cgccagagccgcaactacctgggcggcttcgcgctgtcggtggcgcacgggaggaaggcg
caccactacaccatcgagcgcgagatgaacggcacctacgccatcgcgggcggcaggacg
cacggcagcccggccgagctgtgccactaccactcccaggagtccgacggcctcgtctgc
ctcctcaagcagcccttccaccggccgcccggggtgcagcccaagaccggcccgttcgag
gatctgaaggagagcctcatcagggagtacgtgaagcagacctggaacctgcagggtcag
gctctggagcaggccattatcagccagaaacctcagctggagaagctgatcgccaccacg
gcccacgaaaaaatgccctggttccacgggaagatctcacgagttgaatctgagcaaatt
gtcatgataggctccaagacaaatggaaaatttttgatcagggacagaaatgacaatggg
tcttatgccctgtgcctgctgcacgagggaaaggtgttgcactaccgcatcgataaggac
aaaacggggaagctgtccatccctgatgggaagaagttcgacacactctggcagctagtg
gagcattactcttataaaccagatgggcttctaagagttctcacagttccatgccagaaa
attggcgggcagccaggaaacatcaacttcggagcccgtgcgcccctccctggtgcccat
cctgcgacatggtcggcgggtggaataatctcaaggatcaaatcctacaccttcccaaag
cctggccacagaaaggctgcctcgtctacagggagccggccagaaagctccttcaatcct
tacgagccggaccgggggccctgggccacggacagagacgcccagagagaggccttgccc
atggacacagaagtgtatgaaagcccgtatgccgaccctgaggagatcaggcccaaggag
gtctacctggaccgcaaactgctgaccctggaggacaacgaactgggctctgggaacttc
gggactgtgaagaagggctattaccagatgaaaaaagtcgtgaaaacagtggctgtgaag
attctgaagaatgaggctaatgaccctgctcttaaagatgagttgttagcagaagcgaac
gtcatgcagcagcttgacaacccttacatcgtgcgcatgattgggatctgtgaagccgag
tcctggatgctggtcatggaaatggcagaactgggtccactcaataaatatttacagcag
aacaggcacgtcaaggataagaacattatagagctggttcatcaggtttctatgggaatg
aaatatctggaggagagcaattttgtgcacagagatctggctgcaagaaatgtattgctg
gttactcaacattatgccaagattagtgatttcggactttccaaagcactccgtgctgat
gaaaactactacaaggcccagacccacgggaagtggcccgtgaagtggtacgccccggag
tgcatcaactactacaagttctccagcaagagtgacgtctggagcttcggcgtgttgatg
tgggaggcgttctcctatgggcagaagccctatcggggcatgaaaggaagtgaagtttca
gctatgctggagaaaggagagaggatggggtgccccgcggggtgtccaagggagatgtac
gagctgatgaagctgtgctggacatatgaggtggatcgcaggccggggttcgaagccgtg
gagctgcggctgcgcaattattactacgacgtggtgaactaa
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