Canis lupus familiaris (dog): 484490
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Entry
484490 CDS
T01007
Symbol
AXL
Name
(RefSeq) tyrosine-protein kinase receptor UFO isoform X1
KO
K05115
AXL receptor tyrosine kinase [EC:
2.7.10.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01521
EGFR tyrosine kinase inhibitor resistance
cfa04148
Efferocytosis
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
484490 (AXL)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
484490 (AXL)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
484490 (AXL)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
484490 (AXL)
Protein kinases [BR:
cfa01001
]
Receptor tyrosine kinases (RTK)
AXL family
484490 (AXL)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
fn3
I-set
Ig_2
ig
V-set
C2-set_2
Unc5_NetrinR_N
VEGFR1-3_N_Ig-like
DUF4381
Reovirus_L2_6th
Pkinase_fungal
ABC1
Fend_C
DUF2627
Motif
Other DBs
NCBI-GeneID:
484490
NCBI-ProteinID:
XP_038301305
Ensembl:
ENSCAFG00000005041
VGNC:
38326
UniProt:
A0A8I3MNJ9
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Position
1
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AA seq
879 aa
AA seq
DB search
MGRVPLAWCLALCCWGCLAPPAGTQAEADPFVGSPRNITGARGLTGALRCELQVQGEPPE
VTWLRDGQVLELADSTQTQVPLGEDGQDDWKVVSQLRISSLQLSDAGWYQCAVVLGGKTF
VSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCRAEGPPEPVDLLWLQDAVPLPLAATH
SAQHTLRIPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQRPRNLHLVSRQPTELEVAWT
PGLSGIYPLTHCTLQAVLSDDGVGVQLGEPDPPEEPLTLQAFVPPHQLRLGSLHPHTPYH
IRVACTSSQGPSPWTHWLPVETPEGVPLGPPENVSALRNGSQALVRWQEPRAPLQGTLLG
YRLAYRGQDTPEVLMDIGLKREVTLELQGDGTVPNLTVCVAAYTAAGDGPWSLPVPLEPW
RPVSEPPAPAFSWPWWYVLLGAVVAAGCVLILALFLVHRRKKETRYGEVFEPTVERGELV
VRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQL
NQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSEREGFPA
PVVILPFMKHGDLHSFLLYSRLGDQPVFLPTQMLVKFMADIASGMEYLSTKRFIHRDLAA
RNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWSF
GVTMWEIATRGQTPYPGVENSEIYDYLCQGNRLKQPVGCLDGLYALMSRCWELNPRDRPS
FSELREDLENTLKALPPAQEPEEILYVNMDEGGSHSEPLGAAGGADPPTQPDPKDSCSCL
TAAEVHPAGRYVLCPSTAPGPALPTDRSSPAPPGQEDGA
NT seq
2640 nt
NT seq
+upstream
nt +downstream
nt
atgggcagggtcccgctggcctggtgcttggcgctgtgctgctgggggtgcctggccccc
ccggcaggcacacaggctgaggcagacccctttgtggggagtccaaggaacatcaccggt
gcccgaggactcaccggggcccttcggtgtgagctccaggttcagggggagccccctgag
gtgacgtggcttcgggatggacaggtgctggagctggcggacagtacccagacccaggtg
cccctgggtgaagacgggcaggatgactggaaggtggtcagccaactcagaatctcatcc
ctgcagctctcagacgccgggtggtaccaatgtgccgtggtcctgggaggaaagaccttc
gtgtcgcagcctggctacgttgggctggagggcctgccttacttcctggaggagcccgag
gacagaaccgtggccgccaataccccctttaacctgagctgccgggctgagggaccccca
gagcctgtggatctactctggctccaggatgccgtccccctacctctagccgcgacccac
agtgcccagcacacgctgcgcattccaggcttgaacaagacatcttctttctcctgtgaa
gcccataatgccaagggggtcaccacatcccgcacagccaccatcacagtgctcccccag
cggccccgcaacctccacctggtttcccgccagcccacagagctggaggtggcttggact
ccaggcctgagtggcatctatcccctcacgcactgcaccctgcaggctgtgctgtcagat
gatggggtgggtgtccagctgggagagccagaccccccggaggagcctctcaccttgcaa
gcgtttgtcccccctcaccaacttcggctgggcagcctccatcctcacactccttaccac
atccgggtggcctgtaccagtagccaggggccctcaccctggacccactggcttcctgtg
gagacaccagagggagtgcccctgggtccccccgagaacgttagcgccttgcggaatggg
agccaagccctcgtgcgttggcaggagccaagggcgcccctgcagggcaccctgttaggg
taccggctggcctaccgaggccaggacacccccgaggtgctcatggacatagggctaaag
agagaggtgaccctggagctgcaaggggatgggacggtgcccaacctgacagtgtgtgtg
gcagcctacactgctgctggggatggaccctggagcctccctgtgcccctggagccctgg
cgcccagtgagtgagcccccagcccctgccttctcatggccctggtggtatgtattgctg
ggagcagtcgtggctgccggttgtgtcctcatcttggccctgttccttgtccaccggcgg
aagaaggagacccgctatggagaggtgtttgaaccaacagtggagaggggtgagctggtg
gttaggtaccgtgttcgcaagtcctacagtcgccggaccactgaagccaccttgaacagc
ctgggcatcagtgaagagctgaaggagaagcttcgggatgtgatggtggaccggcataag
gtggcgctggggaagaccctgggagaaggagaatttggagcagtgatggagggccagctc
aaccaggatgactctatcctcaaggtggctgtgaagacaatgaagattgctatctgcaca
aggtcggagctggaggatttcctgagtgaagctgtctgcatgaaggaatttgaccacccc
aacgtgatgaggctcattggcgtctgtttccagggttccgaacgagagggcttcccggca
ccggtggtcatcttacctttcatgaagcatggagacctgcacagtttccttctctattcc
cggcttggggaccagccagtgttcctgcccactcagatgctggtgaagttcatggcagac
atcgccagtggcatggagtatctgagtaccaagagattcatacaccgagacctggccgcc
aggaactgcatgctgaatgagaacatgtccgtgtgtgtggcggattttgggctttccaag
aagatctacaatggggactactaccgccagggacgcatcgccaagatgccagtcaagtgg
attgccattgagagcctggctgaccgtgtctacaccagcaagagtgatgtgtggtccttt
ggggtgacgatgtgggagattgctacacggggccaaaccccatatccaggagtggaaaac
agcgagatttacgactacctgtgccagggaaatcgactaaagcagcctgtgggctgtctg
gatggactgtatgccctgatgtcccggtgctgggagctaaacccccgggaccggccgagt
ttctcagagcttcgggaagatctggagaacacactgaaagccctgccccctgcccaggag
cccgaggaaatcctctatgtcaacatggatgagggtgggagtcattctgaaccacttgga
gctgctggaggagctgaccccccaactcagcctgaccccaaggattcctgcagttgcctc
accgcggctgaggtccatcctgctggacgctatgtcctctgcccttctacagcccctggc
cccgccctgcctactgacaggagctccccagctcctccagggcaggaggatggagcctga
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