Canis lupus familiaris (dog): 484724
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Entry
484724 CDS
T01007
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X15
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04010
MAPK signaling pathway
cfa04020
Calcium signaling pathway
cfa04022
cGMP-PKG signaling pathway
cfa04024
cAMP signaling pathway
cfa04218
Cellular senescence
cfa04260
Cardiac muscle contraction
cfa04261
Adrenergic signaling in cardiomyocytes
cfa04270
Vascular smooth muscle contraction
cfa04530
Tight junction
cfa04713
Circadian entrainment
cfa04723
Retrograde endocannabinoid signaling
cfa04724
Glutamatergic synapse
cfa04725
Cholinergic synapse
cfa04726
Serotonergic synapse
cfa04727
GABAergic synapse
cfa04728
Dopaminergic synapse
cfa04911
Insulin secretion
cfa04912
GnRH signaling pathway
cfa04921
Oxytocin signaling pathway
cfa04924
Renin secretion
cfa04925
Aldosterone synthesis and secretion
cfa04927
Cortisol synthesis and secretion
cfa04929
GnRH secretion
cfa04930
Type II diabetes mellitus
cfa04934
Cushing syndrome
cfa04935
Growth hormone synthesis, secretion and action
cfa04973
Carbohydrate digestion and absorption
cfa05010
Alzheimer disease
cfa05020
Prion disease
cfa05022
Pathways of neurodegeneration - multiple diseases
cfa05031
Amphetamine addiction
cfa05207
Chemical carcinogenesis - receptor activation
cfa05410
Hypertrophic cardiomyopathy
cfa05412
Arrhythmogenic right ventricular cardiomyopathy
cfa05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
484724 (CACNA1D)
04020 Calcium signaling pathway
484724 (CACNA1D)
04024 cAMP signaling pathway
484724 (CACNA1D)
04022 cGMP-PKG signaling pathway
484724 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
484724 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
484724 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
484724 (CACNA1D)
04929 GnRH secretion
484724 (CACNA1D)
04912 GnRH signaling pathway
484724 (CACNA1D)
04921 Oxytocin signaling pathway
484724 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
484724 (CACNA1D)
04924 Renin secretion
484724 (CACNA1D)
04925 Aldosterone synthesis and secretion
484724 (CACNA1D)
04927 Cortisol synthesis and secretion
484724 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
484724 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
484724 (CACNA1D)
04270 Vascular smooth muscle contraction
484724 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
484724 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
484724 (CACNA1D)
04727 GABAergic synapse
484724 (CACNA1D)
04725 Cholinergic synapse
484724 (CACNA1D)
04728 Dopaminergic synapse
484724 (CACNA1D)
04726 Serotonergic synapse
484724 (CACNA1D)
04723 Retrograde endocannabinoid signaling
484724 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
484724 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
484724 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
484724 (CACNA1D)
05020 Prion disease
484724 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
484724 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
484724 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
484724 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
484724 (CACNA1D)
05414 Dilated cardiomyopathy
484724 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
484724 (CACNA1D)
04934 Cushing syndrome
484724 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
cfa04040
]
484724 (CACNA1D)
Ion channels [BR:
cfa04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
484724 (CACNA1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
CAC1F_C
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
484724
NCBI-ProteinID:
XP_003432835
Ensembl:
ENSCAFG00000008525
VGNC:
38634
UniProt:
A0A8C0T3X3
A0A8I3PW57
LinkDB
All DBs
Position
20:complement(36127167..36425020)
Genome browser
AA seq
2137 aa
AA seq
DB search
MMMMMMMKNMHHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIIAEEDPAPCAFSGNGRQCAANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GGGENPGGCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTI
SSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIT
ETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLF
IIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGG
PSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARK
ESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPPCDVPVGEEEEEEEEDEPEVP
AGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSS
AALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMATFGAFLHKGAFCRNYFNLLDM
LVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMI
VTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDNPVVRERIWQNS
DFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIVA
FFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWY
VVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFK
PKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEG
IRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQA
VLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLI
INLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPP
LGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRA
VIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKN
TTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKREEEEDGFKRNGALLGNHVNHVNS
DRRDPLQQTNTTHRPLHVQRPSVPPASDTERPLFPPAGNSGCHSHHNHNSVGKQAPSSTN
ANLNNANMSKAAPGKRPSIGNLEHMSENGHHSSHKHDREPQRRSSIKRSDSGDEQFPTIC
REDPEPHGYFRDARCLEEQEYFSGEEGYEDVGSPAGGRQSYNYYNRYPGSSWDFERPRGY
HHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPTSHRRSSFNFECLRRQSSQEEVSLSPTFP
HRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYAPLIQVE
RPEALDQVNGSLPSLHRSSWYTDEPGISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEA
VLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASNLLNGTVHPRANGGVGPVSH
RQDYELQDFGPGYSDEEPDLGRDEEDLADEMICITTL
NT seq
6414 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaacatgcaccaccaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccccacctgtgggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgccctcttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
attgcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattctggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaagtcaggaggcttcgatgtcaaagccctccgc
gcctttcgggtgttacgaccacttcgactcgtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggtccccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaacc
tgtttttttgctgactcagatatcatagctgaagaggacccagcgccatgtgcgttctca
gggaatggacgccagtgtgccgccaatggcacggagtgtaggagtggctgggttggccca
aatggaggcatcaccaattttgataattttgcctttgccatgctcaccgtgttccagtgc
atcaccatggagggctggacagatgtgctctactggatgaatgatgctatgggatttgaa
ttgccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatctt
gtacttggtgtattgagcggagaattctcaaaggaaagagagaaggctaaagcccgggga
gatttccagaagctccgggagaagcagcagctggaggaggatctaaagggctacttggat
tggatcacccaagcagaagacattgatcctgagaacgaggaagaaggaggagaggaaagc
aaacgaaacaccagcatgcccaccagcgagaccgagtcggtgaacacagagaacgtaagt
ggcggaggcgagaatccaggcggctgtgggagtctctgccaagccatctcaaaatccaaa
ctcagccgacgctggcgtcgctggaaccgcttcaatcgcagaagatgtcgtgctgctgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaataccttaaccatt
tcctctgagcactacaatcagcctgactggttgacgcagattcaagatatcgctaacaaa
gtcctcctggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggtctccag
gcctatttcgtctctctcttcaatcggtttgattgcttcgtggtgtgtggtggcattacc
gagaccatcctggtggagctggaaatcatgtctcctctggggatctctgtgtttcggtgc
gtgcgcctcttaaggattttcaaggtgaccaggcactggacttccctgagcaacttagtg
gcctccttgttaaactccatgaagtccatcgcttcgctgttgcttctgctttttctcttc
atcatcatcttttccttgcttgggatgcagctgtttggtggcaagtttaattttgacgaa
acacagaccaagcggagcacctttgacaatttccctcaagcccttctgaccgtattccag
atcctgacaggggaggactggaacgccgtgatgtatgatggcattatggcctatggcggc
ccgtcatcttcggggatgatcgtctgcatctacttcatcatcctcttcatttgtggtaac
tatatcctactgaatgtcttcttggccatcgctgtagacaatctcgctgatgctgaaagt
ttgaatactgcccagaaagaggaagctgaagagaaggagaggaaaaagattgccagaaaa
gagagcctggagaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgac
aataaggttacaattgatgactaccgagaagaggatgaagacaaggacccctacccacct
tgtgatgtgccagtaggggaagaggaagaggaggaggaagaggatgaacctgaggttcct
gctggcccccgtcctcgcagaatctcagagttgaacatgaaggagaaaatcgcccccatc
cctgaaggaagtgcattcttcattctgagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagtagt
gccgcccttgccgccgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctgttaaagatggcgact
tttggagctttcctccacaaaggggctttctgcagaaactacttcaatctgctggatatg
ctggttgttggggtgtcactggtatcatttgggattcaatccagtgccatctccgttgtg
aagattctgagggtcttaagggtcctgcggccactcagggcaataaacagagcaaaagga
cttaagcatgtggtccagtgtgtcttcgtggccatccggaccattggcaacatcatgatc
gtcaccacccttctccagttcatgtttgcctgcatcggagtacagttgttcaagggaaag
ttctatcgctgtacagatgaagccaaaagtaaccccgaagagtgcagggggcttttcatc
ctctacaaggatggggatgttgataaccctgtggtccgggagagaatctggcaaaacagc
gattttaactttgacaacgtcctttctgctatgatggcgctgttcacggtctccacgttc
gagggctggcctgcgttactgtataaagccatcgactcaaatggagagaatgtcggcccc
gtctacaattaccgcgtggagatctccatcttcttcatcatctacatcatcatcgtggct
ttcttcatgatgaacatctttgtgggcttcgtcatcgtcacatttcaggagcagggagag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttg
aaagcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactacgagcagtccaagatgttcaatgacgccatggacattctg
aacatggtcttcactggggtgttcactgtcgagatggttttgaaagtcatcgcatttaaa
cctaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggccctcagcgaagccgacaactctgaagagagcaatagaatctccatc
acctttttccgtcttttccgagtgatgcggttggtgaaacttctcagcaggggggaaggc
atccggacgttgctgtggacttttataaagtcctttcaggctctgccctatgtcgccctc
ctcatagccatgctgttcttcatctacgcggttatcggcatgcagatgtttggaaaggtt
gctatgagagataacaaccagatcaacaggaacaacaatttccagacctttcctcaggcg
gtgctgctactcttcaggtgtgccacgggtgaagcctggcaggagatcatgctggcctgt
ctcccggggaagctctgtgaccccgagtcagactataaccctggggaggagtacacatgt
gggagcaactttgccattgtttatttcatcagtttttacatgctctgcgcatttctgatc
atcaacctgtttgtggctgtcatcatggacaactttgattatctgactcgggactggtcc
attctagggcctcaccatttagacgaattcaaaagaatatggtcagaatatgaccctgag
gcaaaaggaaggatcaagcaccttgatgtggtcactctgctccgacgcatccagcctccc
ctggggtttgggaaattatgcccacacagagtagcctgtaagagactagttgccatgaac
atgcctctcaacagtgatgggacagtcatgtttaatgcaaccctgtttgctttggttcga
acggctcttaaaatcaagacagaagggaacctggaacaagctaatgaggaactccgagct
gtgataaagaaaatctggaagaaaaccagcatgaaactgcttgaccaagttgtccctcca
gctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgatacaggactac
tttaggaaattcaagaaacggaaagaacaaggactggtgggaaaataccctgcgaagaac
accaccattgccctacaggcaggattaaggacactgcatgacattgggccagaaatccgg
cgtgctatatcatgtgatttgcaagatgacgagccggaggaaacaaaacgagaagaagaa
gaagatggattcaaaagaaatggtgccctgcttggaaaccatgtcaatcatgttaatagt
gataggagagacccccttcagcagaccaataccacccaccgtcccctgcatgtccaaagg
ccttcagttccacctgcaagtgatactgagagaccgctgtttcctccagcaggaaattcg
gggtgtcatagccatcataaccataattccgtaggaaagcaagctcccagctcaacaaat
gccaatctcaataatgccaatatgtccaaagctgcccctggaaagcggcccagcattggg
aaccttgagcatatgtctgaaaatgggcatcactcctcccacaagcatgaccgggagcct
caaagaaggtccagtattaaaagatctgactcgggagatgagcagttcccaaccatctgc
cgagaggatccggagccccacggctacttcagggacgcccgctgcttggaggagcaggag
tacttcagcggcgaggagggctatgaggatgtgggctctccggccgggggcaggcagagc
tacaactactacaaccgatacccgggcagcagctgggacttcgagcggccccgaggctac
catcacccccaaggcttcttggaggatgacgactcgcccgtttgctatgactcccggaga
tccccaaggagacgcctactacctcccaccccgacatcgcaccggagatcctccttcaac
tttgagtgcctgcgccggcagagcagccaggaggaggtctcgctgtcccccaccttcccc
caccgcacagccctgccactgcacctgatgcagcaacagatcatggcagttgcgggcctg
gattccagtaaagcccagaagtactcgccgagccactcaacccggtcgtgggccacccct
ccagcgacccctccgtaccgagactggacgccgtgctacgcgcccctgatccaggtggag
cggccagaggccctggaccaggtcaacggcagccttccatccctgcaccgaagctcatgg
tacacggacgagcccggcatctcataccgaactttcacaccagccagcctgactgtcccc
agcagcttccgcaacaaaaacagtgacaagcagaggagtgcagacagcttggtggaggca
gtcctgatatccgaaggcttaggacggtatgcaagggacccaaaatttgtatcggcaaca
aaacacgaaatcgccgatgcctgtgacctgaccatcgatgagatggagagcgcagccagc
aacctgctcaatgggactgtgcatccccgggctaacgggggcgtgggccctgtctcacac
cggcaggactatgagctccaggactttgggccgggctacagcgatgaggagcctgacctc
ggaagagatgaggaggacctggcagatgaaatgatatgcatcaccaccctgtag
DBGET
integrated database retrieval system
