| Entry |
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| Symbol |
ABCC4
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| Name |
(RefSeq) multidrug resistance-associated protein 4
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| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
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| Organism |
cfa Canis lupus familiaris (dog)
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| Pathway |
| cfa04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:cfa00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
485523 (ABCC4)
09132 Signal transduction
04024 cAMP signaling pathway
485523 (ABCC4)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
485523 (ABCC4)
04981 Folate transport and metabolism
485523 (ABCC4)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
485523 (ABCC4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:cfa02000]
485523 (ABCC4)
Transporters [BR:cfa02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
485523 (ABCC4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
22:complement(45552541..45797861)
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| AA seq |
1326 aa
MLPVYPEVKPNPLQDANLCSRVLFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSKHLGEEL
QGYWDKEIQKAEKSDARKPSLTKAIIKCYWKSYLVLGIFTLIEEGTRVIQPIFLGKIIKY
FENQDPNDSVALHEAYGYATVLTACTLVLAILHHLYFYHVQCAGMRLRVAMCHMIYRKAL
RLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLA
GMVVLIILLPLQSCIGKLFSSLRSKTATFTDVRIRTMNEVITGIRIIKMYAWEKSFADLI
TNLRRKEISKILRSSYLRGMNLASFFVANKIIIFVTFTTYVLLGNVITASRVFVAVSLYG
AVRLTVTLFFPSAIERVSESVVSIQRIKNFLLLDEISQRTPQLPSDGKMIVHIQDFTAFW
DKASETPTLEGLSFTVRPGELLAVIGPVGAGKSSLLSAVLGELPRNQGLVSVHGRIAYVS
QQPWVFPGTVRSNILFGKKYEKERYEKVIKACALRKDLQCLEDGDLTVIGDRGATLSGGQ
KARINLARAVYQDADIYLLDDPLSAVDAEVGRHLFELCICQTLHEKITILVTHQLQYLKA
ASQILILKEGKMVQKGTYTEFLKSGVDFGSLLKKENEEADQSPAPGSPILRTRSFSESSL
WSQQSSRHSLKDSAPEAQDIENTQVALSEERRSEGKVGFKAYRNYLTAGAHWFVIVFLIL
LNIASQVAYVLQDWWLSYWANEQSALNVTVDGKENVTEKLDLPWYLGIYSGLTVATVLFG
IARSLLMFYVLVNSSQTLHNKMFESILRAPVLFFDTNPIGRILNRFSKDIGHMDDLLPLT
FLDFLQTFLQVLGVVGVAVAVIPWIAIPLLPLAIIFFILRRYFLATSRDVKRLESTSRSP
VFSHLSSSLQGLWTIRAYKAEERFQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMF
VIVVAFGSLILAKTVDAGQVGLALSYALTLMGMFQWSVRQSAEVENMMISVERVMEYTDL
EKEAPWEYQKRPPPTWPQEGTIVFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRTGA
GKSSLIAALFRLSEPEGKIWIDRILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFN
EHTDEELWNALTEVQLKDAVEDLPGKLDTELAESGSNFSVGQRQLVCLARAILRKNRILI
IDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPY
VLLQNEESLFYKMVQQLGKAAAAALTETAKQVYFKRNYPDITQNGHVVMNASNGQPSAFT
IFETAL |
|---|
| NT seq |
3981 nt +upstreamnt +downstreamnt
atgctgcccgtgtacccggaggtgaagcccaacccgctgcaggacgccaacctctgctcg
cgcgtgctgttctggtggttgaaccccttgtttaaaattggtcacaaacggagattagaa
gaagatgatatgtattccgtgcttccagaagaccgctccaagcacctgggagaagagttg
caagggtactgggataaagaaattcagaaagccgagaagtcggacgcacggaaaccttct
ttaacgaaagcaatcataaagtgttactggaaatcctatttagttttgggaatttttacg
ctaattgaggaagggaccagagtaatccagcccatatttttggggaaaattattaagtat
tttgaaaaccaggaccctaatgattctgtggctctgcacgaagcctacggctatgccacg
gtgctgaccgcctgcacacttgttctcgccatactgcaccacttatacttttatcatgtt
cagtgtgctggcatgaggttaagagttgccatgtgccatatgatttatcggaaggcactt
cgccttagtaacatggccatggggaagaccactaccggccagattgtcaacctgctgtcc
aatgacgtgaacaagtttgaccaggtgacagtattcttgcactttctgtgggcaggacca
ctgcaagctattgcagtgactgctttgctctggatggaaataggaatatcctgtcttgcc
gggatggtagttctaattattcttctacccttgcaaagctgcattgggaagttgttttca
tcactccggagtaagactgcaactttcacagatgtcaggatcagaaccatgaatgaagtt
ataactggcataagaataataaaaatgtatgcctgggaaaagtcctttgcggatcttatc
accaatttgcgaaggaaggaaatttccaagattctgagaagctcctacctcagaggaatg
aatttggcatcatttttcgttgcaaacaaaatcatcatttttgtgactttcaccacctac
gtgcttcttggcaacgtgatcacagccagccgtgtgtttgtggcagtgtcgttgtatggg
gctgtgcggttgaccgtcaccctcttcttcccctcggccattgagagggtgtccgaatca
gtcgtcagcatccaaagaatcaagaactttctgttacttgatgagatatcccagcgcacc
cctcagctgccatcagatgggaaaatgatagtgcatatacaggacttcaccgccttttgg
gacaaggcatcagaaaccccaaccctagaaggcctttcctttactgtgagacctggggaa
ttgttagctgtgattggacctgtgggagcaggaaagtcctcgctgctaagtgctgtcctg
ggggaactgccccggaaccaggggctggtcagcgtgcacggaaggatcgcctatgtttcg
cagcagccctgggtgtttccaggaactgtgaggagtaatattttatttgggaagaaatac
gaaaaggaacgatatgaaaaagtaataaaagcttgtgcgctgagaaaggatttgcagtgt
ttggaggatggagatttaaccgtgataggtgatcggggagcgacactgagtggagggcaa
aaggcccggatcaaccttgcaagagcagtgtatcaggacgcagacatctacctcctggac
gatcctctcagcgcagtagatgcggaagttggcaggcatttgtttgaactgtgtatttgc
cagaccttgcatgagaagatcacaatcttagtgactcaccagttgcagtacctaaaagct
gcaagtcagattctgatattgaaagaaggcaaaatggtgcaaaagggcacctacacagag
tttctgaaatccggggtagatttcggctctcttttgaagaaggaaaatgaggaggctgac
cagagtccagctccaggatctcccatcctgaggactcggagcttctcagagtcttctctt
tggtcccagcaatcttcaagacactcgctgaaagatagcgctcctgaggcacaagatatt
gagaatacacaggttgctttgtcagaggagaggcgttcagaaggaaaagttggttttaag
gcctataggaattacttaacagccggtgctcactggtttgtcatcgttttccttattcta
ctaaacatcgcatctcaggttgcctatgttcttcaggactggtggctgtcctattgggca
aatgaacaaagtgccctgaatgtcacggtagatggaaaagaaaatgtcactgagaagctc
gatcttccctggtacttaggaatttattcaggtttgacggtggctactgttctttttggc
atcgcgagatctctgttgatgttctatgtccttgttaattcttcacaaactttgcacaac
aaaatgtttgagtccattttgagagctccagtgttgttctttgatacaaacccaatagga
agaattttaaatcgtttctccaaagacattgggcacatggatgacttgctacccctgacg
tttctagatttcctccagacatttctgcaagttcttggtgttgttggagtggcagtggcg
gtgattccttggatcgcaatacctctgcttccccttgccatcattttcttcattcttcgg
cgatatttcttagcaacgtcgagggatgtcaaacgcttggagtctacaagccggagtccg
gtattctcccatttatcgtcctctctccaggggctttggaccatccgggcatataaagca
gaagaaaggtttcaggaactgttcgatgcacatcaggatttgcattcagaggcatggttc
ttgtttctgactacgtcccgatggttcgctgtgcgtctggatgccatctgtgccatgttt
gtcattgttgttgcctttgggtctctgattctggcaaaaactgtagatgccgggcaggtt
ggcctggcactgtcctacgccctcacgctcatggggatgttccagtggtccgtcaggcaa
agtgccgaagtggagaatatgatgatttcagtggaacgagtgatggaatatacagacctt
gagaaagaagccccctgggaataccagaaacgacctccacccacctggccccaggaaggc
acgattgtctttgataatgtgaacttcacatatagtttagacggacctctggtgttgaag
cacctgaccgcactcattaaatcaagggaaaaggttggcattgtgggaagaacaggggct
ggaaagagttccctcatcgcggccctttttagattgtcagaaccagaaggtaaaatttgg
atcgacaggatcttgacaacagaaattggacttcacgatttaaggaagaaaatgtccatc
ataccccaggagcctgttttattcactggaacaatgaggaaaaatctggatccctttaat
gagcatacggatgaggaactgtggaatgccttaacagaggtacagcttaaagacgctgtt
gaagatcttcctggcaaattggacactgaattagcagaatcaggatcgaactttagtgtt
ggacagagacagttggtgtgtcttgccagggctatcctcaggaaaaatcggatattgatc
attgatgaagcgacagcaaatgtggatcccagaactgatgagttaatacaaaaaaaaatc
cgtgagaaatttgcccactgcactgtgctaaccattgcacacaggttgaacaccattatt
gacagcgacaagataatggttttggattcaggacgactgaaagaatatgatgaaccatat
gttttgctgcagaatgaagagagcctgttttacaagatggtgcagcaactgggcaaggca
gcagcggcggccctcactgaaacagcaaaacaggtgtacttcaaaaggaattacccagat
attactcagaatggccacgtggttatgaatgcttccaatggacagccctcagcctttact
attttcgagacagcactgtga |
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