Canis lupus familiaris (dog): 486002
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Entry
486002 CDS
T01007
Symbol
FREM2
Name
(RefSeq) FRAS1-related extracellular matrix protein 2 isoform X1
KO
K23380
FRAS1-related extracelluar matrix protein 1/2
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04512
ECM-receptor interaction
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04512 ECM-receptor interaction
486002 (FREM2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04091 Lectins [BR:
cfa04091
]
486002 (FREM2)
Lectins [BR:
cfa04091
]
C-Type lectins
Lecticans
486002 (FREM2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Cadherin_3
Frem_N
Calx-beta
Big_9
Cadherin_4
Motif
Other DBs
NCBI-GeneID:
486002
NCBI-ProteinID:
XP_038314221
Ensembl:
ENSCAFG00000006019
VGNC:
40977
UniProt:
A0A8P0SBG2
LinkDB
All DBs
Position
25:complement(2193436..2359496)
Genome browser
AA seq
3169 aa
AA seq
DB search
MRAAGAPGIASRAATGAQPVPRLPPPLLLLLPLLLSPVSRARAQPAAPGRELLSPDPAGA
AGVLAEEAVVLANRGLRVPFGREVWLDPRRDLVLQVQPGDRCAVTVLDSDALAQRPGRLS
PKRFPCDFGPGEVRYSHLGARSPSRDRVRLQLRYDAPGGAAVLPLALEVEVVFTQLEVVT
RNLPLVVEELLGTSNALDARSLEFAYQPETEECRVGILSGLSALPRYGELLRYPQVPGGA
GDGGAQEPLLMDCKAFQELGVRYRHTAPGRSPNRDWVPMVVELRARGSPVGRPALKREHF
QVLVRIRGGAENTAPKPSFVAMMMVEVDQFVLTALTPDMLAAEDAESPPDLLVFNLTAPF
QLGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQPPSEDSDRERLFELELEVVDPEGAASD
PFAFMVVVKPMNTLAPVVTRNTGLLLYEGQSRPLTGPAGSGPQNLVISDEDDLEAVQLEV
VAGLRHGHLVLLGATHGNSAPKTFSVAELAAGQVVYHHDDKDGSLSDNLVLRMVDGGRRH
QVQFLFPITLVPVDDQPPVLNANTGLTLAEGETVPILPLALSAADIDSEDSLLLFVLESP
FSAIGHLLLRQTHPPHEEEEFTGSPWRKQGEFYEKAVTEWRQQDIREGRLFYRHSGPHSP
GPVIDQFTFRVQDNHDPPNQSGPHRFVVRIHPVDRLPPELGSGCPLRMVVQESQLTPLRK
KWLRYTDLDTDDRELHYTVTQPPMDTDENHSPAPLGSLVLTDQPSVVVAHFTQAQINHHK
IAYKPPDQELGVAARVAQFQFQVEDQAGNVAPGTFTLYLQPVDNQPPEILNTGFTVQEKG
HHVLSETELRVDDVDTDVAHISFTLTQAPKHGHVRVSGQILHVGEVFHLEDIKQGRISYA
HNGDESLTDSCSLEVSDTHHVVPITLRVNIQPVDDEVPMLSLSAGTLGSYLDVLENGATE
ITASVIKGTDEDTDDLMLTFLLEDPPLYGEILVNGVPAEQFTQRDILEGSVVYAHTSGEI
GLLPKGDSFNLSLSDMSQEWVIGGSTIQGVTVWVTVLPVDSQAPEISIGEQFIVVEGDKS
VVTSAHISAEDTDSLNDDILCTIVIQPTSGYVENISPAPGSEKSRAGVAISAFTVKDLRQ
SHINYVQSVHKGVEPVEDRFIFRCSDGINFSERHLFPIVIIPTNDEQPEIFMREFMVMEG
MSLVIDTPILNAADADIPPDDLTFTVTQFPTRGHIVNQLINGTVLVESFTLDQIIESSSI
IYEHDDSETQEDRFVIRLTDGRHSVERTVPIIVIPVDDETPRMTINNGLEIEIGETKIIN
NKILMATDLDSEDKSLVYVIRYGPGHGLLQRQKPTGAFENITLGMNFTQDEVDRNLIQYV
HVGQEGIRDLIKFDVTDGINALIDRYFYISVGSIDTVFPDVISKGVSLKEGGKVTLTTDL
LSTSDLNSPDENLVFTITRAPTRGHLECTDQRGASIMSFTQLQLAGNKIYYIHTADDEVK
MDSFEFQVTDGRNPVFRTFRISISDVDNKKPVVTIHNLVVSEGENKLITPFELTAEDPDT
PDKLLKFIVTQVPVHGQLLFNNTRPAMVFTKQDLNENLISYRHDGTESSEDSFSFTVTDS
SHTEFYVFPDTIFETRRPQVMKIQVLAVDDSIPQIAVNKGASTLRPLATGHLGFMITSKV
LKAEDRDSLRFSLRFIVTGAPQHGYLLNLDRGNHSVTQFTQGDIDDMKICYILKEGANAT
SDVFHFTVEDGGGNKLTKQHFRLNWAWISFEKEYYLINEDSKFLDVVLKRRGFLGETSFI
SIGTRDGTAEKDKDFKGKAQKQVQFNPGQTRATWKVRIMSDGEHEQSETFQVVLSEPVLA
ALEFPTVTTVEIIDPGDESTVFIPQSEYSVEEDVGELFIPIRRSGDVSQELMVICYTQQG
TAGGTVPTSVLSYSDYISRPEDHTSVIRFDKDEHEKMCRIVVIDDSLYEEEETFHVLLSM
PMGGRIGSEFPGTQVTIIPDKDDEPVFYFGDVEYLVDESAGYVELRVWRTGTDLSRSSSV
TVRSRKTDPPSADAGTDYVGISRNLDFAPGVNMQTVRVIILDDLGQPVLEGIEKFELVLR
MPMNAALGEPSKATVSINDSVSDLPKMQFKERVYTGNENDGQIVAMIHRSGDIHYRSSVR
CYTRQGSAQVMTDFEERPNIDSSVILFLPGETEKPCVLELMDDKLYEEVEELRLVLGTPS
SDSPFGAAVGEQNETLIRIQDDADKTVIKFGETRFSVSEPKEPGQSVVVKIPVIRQGDTS
KVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHIVNIEVIFDGIREMREAFTVHLKP
DENMVAETQVTKAIVYIEEMNSMAEVTFPSVPQIVSLLMYDDTSRAKDSAGPVSGYPVVC
ITACNPKYSDYDKTGSICASENINDTLTRYRWLISAPAGPDGVTSPMREVDFDTFFTSSK
MITLDSIYFQPGSRVQCAARAVNANGNEGLELMSPIVTIGREEGLCQPRVPGTVGAEPFS
AKLRYTGPEDPEYTNFIKLTVTMPHIDGMLPVISTKELSNFELTLSPDGSRVGNHQCSNL
LDYTEVKTHHGFLTDATKNPEVIGETHPYQYSSSIRGSSTLRFYRNLNLEACLWEFVSYY
DMSELLTNCGGTIGTDGQVLNLVQSYVTLRVPLYVSYVFHSPVGVGGWQHFDLKSELRLT
FVYDTAILWNEGIGSPPEAELQGSLYPTSMRIGEEGRLVVNFKTEAQFHGLFVLSHPASF
TSSMIMSADHPGLTFSLRLIRSEPTYNQPVQQWSFVSDFAVRDYSGTYTVKLLPCTAPSH
QEYHLPVTCSPREPITFDLDIRFQQVSDPVAAEFSLNTQMYLLSKKSLWLSDGSMGFGQE
SDVAFTEGDIIYGRVMVDPVQNLGDSFYCSIEKVFLCTGADGYVPKYNPTNAEYGCLADS
PSLLYRFKIVDKAQPETQAISFGNVLFNAKLAMDDPEAILLVNQPGSDGFKVDSMPLFQV
ALGREWYIHTVYTVRSKDNANRGIGKRSTEHQHHSLVRPGKPQATSKGRKKREIRSPPPL
AWQIGAENNRGTNIQHIALDRSSRKLIPQGRVPPDGVLPRELNRPSSEVSLVTVVGGIAV
GLLTLCLAAITVMMCKSKKGSRRKDALKCSGSSKPMMPPQSHHCDSSEV
NT seq
9510 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgcggccggggcccccgggatcgcgtcccgcgccgccaccggtgctcagccggtg
ccccggctgccgcctcccctgctgttgctactgccgcttctcctgtccccggtaagccgc
gcccgggcacagcccgctgccccgggccgggagctgctgtccccggatcccgcgggcgct
gcgggggtcctcgccgaggaggccgtggtgctggcgaaccgggggctccgggtgcccttc
ggccgcgaggtctggctggatccgcggcgcgacctggtgctgcaggtgcagccgggggac
cgctgcgcggtgaccgtgctggacagtgacgcgctggcgcagaggccgggccgcctgagc
cccaagcgcttcccgtgcgacttcggccccggggaggtgcgctactcgcacctgggcgct
cgcagcccgtcgcgggaccgcgtgcggctgcagctgcgctacgacgcgccgggaggggcc
gcagtgctaccgttggcgctggaggtggaggtggtcttcacccagctggaggtcgtgact
cggaacctgcccctcgtcgtggaggagctgctggggaccagcaacgccctggacgcgcgg
agcctggagttcgcctaccagcccgagaccgaggagtgtcgcgtgggcatcctgtcgggc
ttgagcgcgctgccccgctacggggaactgctgcgctacccgcaggttcccggtggagcc
ggcgacgggggcgcccaggagcctctcctgatggactgcaaggccttccaggagctgggc
gtgcgctaccgccacacggcccccggccggtcgcccaacagggactgggtgcccatggtg
gtggagctgcgcgctcgaggctcgccagtgggcaggcctgctttgaaacgggagcacttc
caggtgctggtgagaatccgagggggggcggagaacactgcgcccaagcccagttttgtg
gccatgatgatggtggaggtggatcagtttgtcctgaccgccctgacccccgacatgctg
gcggcggaggatgcagagtcgccccctgacctgctggtcttcaacctcaccgctcccttc
cagctgggccagggctacctggtaagtaccgatgaccgcagcctgcccctctcctccttc
actcagagggatctgcggctcctgaagatcgcctaccagccgccctctgaggactctgac
cgagagcggctctttgaactggagttggaggtagtggatccagaaggagcagcctcagac
ccttttgctttcatggttgtggtgaagcccatgaacacgctggctccagtggtcacccgg
aacacaggcctccttctctacgagggccagtcccggcccctcacaggccccgcaggcagt
ggaccacaaaacttggtcatcagcgatgaggatgacctggaggcagtgcagctggaggtg
gtggctgggctccggcatggtcaccttgtcctcctgggtgccacccacggcaactcggcc
cctaagaccttttcggtggccgagctagcggccggccaggtggtctaccatcatgatgac
aaagatggctcactgagtgacaaccttgtacttcgaatggtggacggaggacgcaggcac
caggtgcagttcctgtttcccatcaccttagtgcctgtggatgaccagccaccagtcctc
aatgctaacacggggctgacactggcggaaggtgaaacggtgcccatcctgccccttgct
ctaagtgcagctgacattgactcagaggactctctgctactttttgtgctggaatcgccc
ttctcagcgatagggcatctgcttctccgccaaactcatcctccgcacgaggaggaggag
tttactgggagcccttggaggaaacagggagagttctatgagaaagcagtgacagaatgg
cggcagcaggacataagagaggggaggctgttctacaggcactcggggccccatagtcct
gggccagtgattgaccagttcacgtttcgcgtccaagataaccatgacccccctaatcag
tcaggaccgcacaggtttgtggtgcgcattcatccggtggatcgcctccctccagagttg
ggcagtggctgtcccctgcggatggtggtgcaggagtcccagctcaccccgctgaggaag
aagtggctgcgctacaccgacctggacacagatgaccgggaactccattacacggtgacc
cagccccccatggacacagatgaaaaccactcgccagcccccctgggctccctggtccta
acagaccagccctcggtcgtggtggcccatttcacccaagcccagatcaaccaccataaa
attgcttacaaacctccagatcaagaactaggagtggctgcccgagtggcccagttccag
ttccaggtggaagaccaagctgggaatgtggccccaggcaccttcaccctttacctgcag
ccagtggacaaccaaccacctgagatcctcaacactggtttcactgttcaggagaagggc
caccatgtcctgagcgagaccgagttgcgtgtggatgacgtagacacagacgtggcacac
atctctttcactctcactcaggcacccaaacacggccacgtgagagtgtctggacagatt
ttgcacgtaggggaggtcttccacttggaagatataaaacagggtcggatttcctatgca
cataatggagatgagtccctcactgacagctgctccttggaggtcagcgacacgcaccac
gtggtgccaatcactctcagagtgaacatccagccagtggatgatgaggtgcccatgctg
agcctttctgctggcactctggggtcatatctagatgttttagaaaatggagctaccgaa
atcactgccagtgttatcaaggggactgatgaggacactgatgacttgatgttgactttc
ctcttggaagatccacccttatatggtgaaatcctggtcaacggagttccagcagagcag
tttacccaaagagacattttagagggctctgtcgtctatgcccacactagtggtgagata
ggcctgttgcccaaaggggactcttttaacctgagcctgtcggatatgtctcaagaatgg
gtaataggtggcagtactatccaaggagtcaccgtgtgggtgaccgtcctccctgtcgat
agccaggctccagaaatttctataggtgaacagtttatagttgtggaaggtgataagagt
gttgtaacatcagcacatataagtgctgaagataccgattcactaaatgatgacatctta
tgcactatagttattcagcctacgtccggttatgttgaaaacatttctccagccccaggc
tctgagaagtcaagagcaggagttgccataagtgcctttaccgtgaaagacctcaggcag
agtcatattaactatgtccagagtgtccataaaggggtagaacctgtggaagatcgattt
atatttcgttgctctgatggcattaacttttcagagagacatttattccccattgtcatc
attcccaccaatgatgaacagccagaaatatttatgagagaatttatggtgatggaaggc
atgagtctggtgatcgacacgcccatcctcaatgctgctgatgctgacattccccccgat
gacttaacttttactgttacccaatttcctactcgcggtcacattgtgaaccagctgata
aatggcacagttttggttgaaagctttaccttggaccagatcatagagagttctagcatt
atttatgagcatgatgactctgagacccaggaagaccgttttgtgattagactaacagat
ggtaggcattcagtggaaaggacggtccccattattgttatcccagttgatgatgagacc
cccagaatgaccatcaataatggactagaaatagaaattggggaaaccaaaattatcaac
aacaaaatattaatggcaactgatttagattcggaagacaaatctttggtttatgttatt
cgttatgggccaggacatggcttattgcagaggcaaaaacctacaggtgcctttgaaaat
atcacactcggcatgaattttacccaggatgaagtggacagaaacttaattcagtatgtc
catgttggacaagagggcattcgggaccttattaaatttgatgtgactgacggaataaac
gccctgatagatcgctacttttacatttccgtcgggagtattgacactgtcttcccagat
gtgataagcaagggggtatccttgaaagaaggaggcaaagtcaccctcacaacagacctc
ctaagcacaagtgacctgaacagtcctgatgaaaacttagttttcaccatcaccagggct
cccacgagaggtcacttagagtgcacagatcaacgtggagcttccatcatgtctttcact
cagctccaactggctggcaacaaaatctactacatccacacagctgatgatgaggtcaag
atggacagttttgagtttcaagtcacggatggacgtaaccctgtcttccggacattccgt
atctccattagtgatgtggataacaaaaagccagtagtcaccatccataacctggttgtc
agcgagggtgaaaacaagctgatcactccctttgaactcactgccgaagacccagatact
cctgacaaactcctgaagttcatcgtcacccaggtgcctgttcatggtcaactcttattc
aacaataccagacctgccatggtttttaccaagcaagacttgaatgaaaacttaatcagc
tacagacatgatggcaccgagtcaagcgaagacagcttctccttcacggtgactgacagt
tctcatacagagttctatgtcttccctgatacaatatttgaaacgaggagaccccaagtg
atgaaaatccaggtcttagctgttgacgatagcatcccccagattgcagtgaacaaaggg
gcttccacgcttcgccctctggctaccggccacttggggttcatgatcacaagcaaagta
ttgaaagcagaggacagagacagcttacgtttttctctcaggtttattgtgacaggagct
cctcaacatgggtatctcctcaatctggacagaggcaaccacagtgtcactcagtttaca
caaggtgacattgatgacatgaaaatatgctacattttaaaagagggggccaatgccaca
agtgatgtgttccattttacagttgaagatggtggaggaaacaaattaaccaagcaacat
tttcgtctgaattgggcatggatctcctttgaaaaggaatattacctgatcaatgaggac
tccaaatttctagatgtcgttcttaaacgtagagggtttttgggagagacttcatttata
agtattggcacaagagatgggactgcagaaaaagacaaagacttcaagggcaaagcacag
aaacaagtacagttcaacccaggccagaccagggcaacctggaaagtgcggatcatgagc
gatggggagcatgagcagtcggagaccttccaggtggttctctcagagccggtgctggct
gctttggagtttcccacagtgaccacagtggagatcattgacccaggagatgagtcaact
gtatttattccccagtctgaatactctgttgaagaagacgtcggtgagctgttcattccc
attaggaggagtggagacgtgagccaggagctgatggtgatctgttacacacaacaagga
acagcaggcggaactgtaccaacatcagtgctgtcctattcagactacatatccaggccg
gaggaccacaccagtgtcatccgctttgacaaagatgaacacgagaaaatgtgtcgcatc
gttgttattgatgactccctgtatgaagaggaggaaacattccatgtccttctgagcatg
cccatgggagggaggattggatcagagttcccagggactcaggttacaatcatccctgac
aaagatgatgaacctgtcttctactttggtgatgtcgagtacctggtggacgagagcgcc
ggctatgtggaattgcgggtgtggagaacaggcaccgacctgtccaggtcttccagtgtc
accgtgaggtctcggaaaacagatcctccctctgctgatgccggaacagattatgtggga
atcagtcggaatttagattttgcacctggagtcaacatgcagactgttcgtgttatcatc
ctggatgatcttgggcaaccagtgctggagggaattgagaaatttgaactggtgcttcgt
atgcctatgaacgctgccctcggcgagcccagcaaagccacggtttccataaatgattct
gtctccgacttgcctaagatgcagttcaaagaacgagtatatactggcaatgaaaacgat
gggcagatagttgcaatgatccacaggagtggagacattcactataggtcttcagtgaga
tgctacacacgacaggggtctgcacaggtgatgacggactttgaggaacgtccaaacatt
gatagctctgtcatcctgttcctccctggtgagactgaaaagccttgtgtacttgagctg
atggatgacaaactctatgaagaggtagaggaactccgcctggttcttggaaccccaagt
agcgactccccctttggggctgcagttggggaacaaaatgaaactctgataaggatccaa
gatgatgctgataagactgttattaaatttggagaaaccagatttagcgtgagtgaaccc
aaggaaccaggacagtcggtggttgtaaaaattccagtgattcgccaaggagatacttca
aaggtttcaattgtgagagtccacaccaaggatggctcagccacttctggagaagactat
caccctgtgtcagaagaaattgaatttaaggagggagaaacccagcatattgttaacatt
gaagtaatcttcgatgggatcagagagatgagagaggccttcactgtccacctaaaaccc
gatgagaacatggtggcagagacgcaggtcaccaaagccattgtgtatatagaagaaatg
aacagcatggcggaagtcactttcccatctgtccctcaaattgtgtcattactgatgtat
gatgacacttccagagctaaagatagtgcaggacctgtgtctggctatcctgttgtctgt
attacagcttgcaaccctaaatactcagactatgacaaaacaggttctatttgtgcaagt
gaaaatatcaatgacaccttgacccggtaccgatggctaattagtgcacccgctggccct
gatggtgtgaccagccccatgagagaagtggactttgacaccttttttacatcgtccaag
atgatcaccttggattccatatacttccagcccggctccagagtgcagtgtgcggcccgt
gctgtgaatgccaatggcaatgagggcctggagctgatgagccctattgtaaccatcggc
agagaagaaggtctttgtcagcccagggtgccagggacagtgggagcagagccattctca
gctaagctgcgctacacaggccccgaggacccagagtacacgaactttatcaagctcacc
gtcacgatgccacacatagatggtatgctccctgtgatctccactaaagagctttccaac
tttgagctcaccctcagtcctgatggctcaagagttggaaaccaccagtgctccaatctt
ctagattacactgaagtgaagactcaccatggcttcttaactgatgctacgaaaaatcca
gaagtaattggagagactcatccttaccagtacagctcatctatcagaggttccagtacc
ttacgcttctatcgaaacttgaacctggaagcctgtttatgggagtttgttagctactat
gacatgtcagaacttctcaccaactgtggaggaaccatcgggacagacggacaggtcctg
aatctggtgcagtcatatgtgacccttcgggtgcctctgtatgtttcgtatgtgttccat
tcccccgttggcgtagggggctggcagcattttgacttgaagtcggagctccgcctgact
ttcgtgtatgacactgccatcttgtggaatgagggcatcggcagcccaccagaagccgag
ctccaaggttctctctacccgactagcatgcgcattggtgaagaggggcgcttggttgtg
aacttcaagacagaggctcagttccatggattgtttgtgctgtctcatcccgcatccttt
acaagctcaatgatcatgtcagctgatcacccgggcctgaccttctccttgcgcctcatc
aggagtgaaccaacctataaccagccagtgcagcagtggagctttgtgtctgactttgca
gtacgtgactattcggggacctacaccgtgaaactgctaccttgcactgctccatcgcat
caggagtaccacctgccagtcacctgcagccccagagagcccatcacctttgacctcgac
atacgattccagcaggtcagtgatccagtggcggctgagtttagcttgaacacccaaatg
tacctcctgtccaagaagagtctctggttgtctgacggatccatgggatttgggcaagag
agtgatgttgccttcacagaaggtgatataatctatggtcgtgtcatggtagatcctgtc
cagaatctgggtgactccttttactgcagcattgagaaggtgttcttgtgcactggagct
gatggctatgttcccaaatataatcccacaaatgcagaatatggctgcttagccgactct
ccttcactcttatatagatttaaaattgtggacaaagctcaaccagagacacaagccatc
agttttggaaatgtcctgtttaatgccaaactagcaatggatgatcctgaagctattctc
ttagtgaatcagcctggatctgatggatttaaagtcgactccatgccactctttcaggtc
gctctgggccgagaatggtacatacacacggtctacacagtaagatcaaaagacaacgcc
aatcgaggcattggcaaaagaagcactgagcaccagcaccactccttagtgagaccaggg
aagccccaggcaactagcaagggccggaagaagagggagatcaggagcccacccccactg
gcctggcaaataggtgctgagaacaaccggggaacaaacatccagcacattgccctggac
cgcagcagccggaagctgatcccccaaggccgagttcctcctgacggcgtcctcccccgg
gagctcaaccgtcccagctctgaggtcagcctggtcacagtcgttggcggcatcgcggtg
ggattgctaaccctctgccttgctgccatcacagtgatgatgtgcaagagcaagaagggc
tccaggagaaaggatgctctaaagtgctcaggcagcagcaagcccatgatgcctccgcag
agccaccactgtgacagctcagaggtttga
DBGET
integrated database retrieval system
