KEGG   Canis lupus familiaris (dog): 486493
Entry
486493            CDS       T01007                                 
Symbol
ITGA5
Name
(RefSeq) integrin alpha-5 isoform X1
  KO
K06484  integrin alpha 5
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa03266  Virion - Herpesvirus
cfa04145  Phagosome
cfa04151  PI3K-Akt signaling pathway
cfa04510  Focal adhesion
cfa04512  ECM-receptor interaction
cfa04640  Hematopoietic cell lineage
cfa04810  Regulation of actin cytoskeleton
cfa04820  Cytoskeleton in muscle cells
cfa05100  Bacterial invasion of epithelial cells
cfa05133  Pertussis
cfa05135  Yersinia infection
cfa05165  Human papillomavirus infection
cfa05168  Herpes simplex virus 1 infection
cfa05205  Proteoglycans in cancer
cfa05206  MicroRNAs in cancer
cfa05410  Hypertrophic cardiomyopathy
cfa05412  Arrhythmogenic right ventricular cardiomyopathy
cfa05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03266 Virion - Herpesvirus
    486493 (ITGA5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    486493 (ITGA5)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    486493 (ITGA5)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    486493 (ITGA5)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    486493 (ITGA5)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    486493 (ITGA5)
   04810 Regulation of actin cytoskeleton
    486493 (ITGA5)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    486493 (ITGA5)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    486493 (ITGA5)
   05205 Proteoglycans in cancer
    486493 (ITGA5)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    486493 (ITGA5)
   05165 Human papillomavirus infection
    486493 (ITGA5)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    486493 (ITGA5)
   05133 Pertussis
    486493 (ITGA5)
   05100 Bacterial invasion of epithelial cells
    486493 (ITGA5)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    486493 (ITGA5)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    486493 (ITGA5)
   05414 Dilated cardiomyopathy
    486493 (ITGA5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    486493 (ITGA5)
   04515 Cell adhesion molecules [BR:cfa04515]
    486493 (ITGA5)
   04090 CD molecules [BR:cfa04090]
    486493 (ITGA5)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   486493 (ITGA5)
Cell adhesion molecules [BR:cfa04515]
 Integrins
  Integrin alpha subunits
   486493 (ITGA5)
CD molecules [BR:cfa04090]
 Proteins
  486493 (ITGA5)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_1 Integrin_A_Ig_2 FG-GAP FG-GAP_3 Integrin_alpha ITGAX-like_Ig_3
Other DBs
NCBI-GeneID: 486493
NCBI-ProteinID: XP_005636796
Ensembl: ENSCAFG00000006491
VGNC: 42127
UniProt: A0A8I3S2B2 A0A8P0N936
LinkDB
Position
27:complement(45330567..45350366)
AA seq 1053 aa
MRGAGLPEGAAGARGPRGRPAPPLPLLPLLLLLLLPPPPRAAGFNLDAQAPAVLSGPPRS
FFGFAVDFYRPGARGVSVLVGAPKANTSQPGVLQGGAVYLCPWGAGRGHCTPIEFDSKGS
RVLESSVSSPDGEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKEPLSDPVGTCYL
STDNFTRILEYAPCRSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQ
EQIAESYYPEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNL
TYGYVTILNGSDIRSLYNFSGEQMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGR
PQEVGRVYIYLQHPAGMEPTPTLTLTGQDEFGRFGSSLTPLGDLDQDGYNDIAIGAPFGG
ETQQGVVLIFPGGPGGPGSQPSQVLLPLWAAGHTPHFFGSALRGGRDLDGNGYPDLIVGS
FGVDKAVVYRGRPIVSTSASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVPD
SIGFTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKVYLRNESEFR
DKLSPIHIALNFSLDPQAPVDAHGLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQLE
VFGDQNHVYLGDKNSLNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRNPGNFSSLSC
DYFAVNQSRLLVCDLGNPMKAGASIWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSE
VVSFPLSVEASAQVSLNGVSKPEAVLFPASDWRPREQPQEEGDVGPAVQHVYELINQGPS
SISRGVLELSCPRTLEGQQLLYVTRVEGLSNCTSSHPPNPESLELDPEGPQHHRLQRREA
PGRGPGSSGPQILKCPEAECFRLRCELGPLHRQESRSLQLHFRVWAKTFLQREHQPFSLQ
CEAVYEALRMPYRILPQQLPRRELQVATAVQWTKAEGSHGVPLWIIILAILVGLLLLGLL
IYILYKLGFFKRSLPYGTAMEKAQLKPPATSDA
NT seq 3162 nt   +upstreamnt  +downstreamnt
atgcggggcgcggggctccccgagggcgcggccggggcgcgaggtccccgcgggcgcccg
gccccgccgctgccgctgctgccgctgctgctgctcctgctgctgccgccgccgccccgg
gccgcgggcttcaacctggacgcccaggcccccgccgtgctctcggggccgccgcgctcc
ttcttcggcttcgccgtggacttctaccggccgggggcgcgcggggtcagcgtgctggtg
ggcgcgcccaaggctaacaccagccagcccggagtgctgcaggggggtgccgtctacctc
tgcccctggggcgccggccggggccactgcacgcccattgaatttgacagtaaaggctcc
cgggtcctggagtcgtcggtgtccagcccggacggggaggagcctgtggagtacaagtcc
ttgcagtggttcggagcgacggttcgagcccacggctcctccatcctggcctgtgcgccc
ctgtatagctggcgcacggagaaggagccgctgagcgatcccgtgggcacctgctacctc
tccacggacaatttcacccgaattctggagtacgcaccttgccgctcagacttcagctgg
gccgcgggacagggctactgccaagggggcttcagcgcagagttcaccaagaccggacgt
gtggtcctgggtgggccagggagctacttctggcaaggccagatcctgtctgccacgcag
gagcagatcgcagagtcctattaccccgagtatctgatcaacctggttcaggggcagctg
cagacccgccaggccagctccatctacgacgacagctacctggggtactctgtggcggtg
ggcgagttcagcggtgacgacacggaggactttgtcgctggcgtgcccaaggggaacctc
acctacggttacgtcaccatcctcaatggctcagacatccggtccctctacaacttctca
ggagaacagatggcctcctacttcggctacgcggtggctgccacagacaccaacggggac
gggctggacgacttgctggtgggggcacctctgctcatggagcggacggctgatgggcgg
cctcaggaggtgggcagggtctacatctacctgcagcacccagctggcatggagcccaca
cccaccctgaccctcactggccaagatgaatttggccgatttggcagctccttgacgccc
ctgggggacctggaccaggacggctacaacgacattgccatcggagcgccctttggcgga
gagacccagcagggagtggtgctcatcttccccgggggccccggggggccgggctctcag
ccgtcccaggttctgctgcccctgtgggcggccggccacacgccacacttcttcggctct
gcgcttcgaggaggccgagacctggacggcaacggatacccggatctgattgtgggctcc
ttcggtgtggacaaggctgtggtgtacaggggtcgccccatcgtctctaccagcgcctcc
ctcaccatcttccccgccatgttcaaccccgaggagcgcagctgcagcttggaggggaac
cccgtggcctgcatcaacctcagcttctgcctcaacgcttccgggaagcacgttcctgat
tccatcggcttcacggtggagctccagctggactggcagaagcagaaggggggcgttcgg
cgggcactgttcctggcctccagacaggcgaccctgacccagaccctcctcatccagaac
ggggctcgggaggactgcagagagatgaaggtctacctcaggaacgagtccgagttccgc
gacaagctgtccccgattcacatcgccctcaacttctccctggacccccaagcccccgtg
gacgcccatggcctccggccagtcttgcattatcagagcaagagccgcatagaagacaag
gctcagatcttgctggactgtggagaagacaacatctgcgtgccggacctgcagctggaa
gtgttcggggaccagaaccacgtgtacctgggcgacaagaactccctgaacctgactttc
catgcccagaacgtgggtgagggcggcgcctatgaggccgagctgcgggtcacggcccct
ccagaggccgagtactcaggactcgtcagaaacccggggaacttctccagcctgagctgt
gactactttgcggtgaaccagagccgcctgctggtgtgtgacctgggcaaccccatgaag
gccggagcgagtatctggggtggcctccggttcacggtccctcacctccgggacacgaag
aaaaccatccagttcgacttccagattctcagcaagaatctcaacaactcccaaagcgaa
gtggtttccttcccgctctcggtggaggcttccgcccaggtctcccttaacggggtctcc
aagcccgaggcagtgctcttcccagcgagcgactggcgtccccgagagcagcctcaggag
gagggagacgtgggccctgctgtgcagcacgtctatgagctcatcaaccagggccccagc
tccatcagccggggtgtgctggagctcagctgtccccggaccctggagggtcagcagctt
ctctacgtgaccagggttgaaggcctcagcaactgcaccagcagtcacccccccaaccca
gagagcctggagttggatccggagggtccccagcaccaccggctacaaagacgggaagcg
ccaggccggggcccgggctcctcgggacctcagatcctgaaatgccccgaggccgagtgc
ttcaggctgcgctgtgagctggggccgctgcaccgccaggagagccgaagtctgcagctg
catttccgagtctgggccaagaccttcctgcaacgggagcaccagccgttcagcctgcag
tgcgaagctgtgtacgaagccctgaggatgccctaccggatcctgccccagcagcttccc
cgaagggaacttcaggtggccacggctgtgcagtggaccaaggcggaaggcagccacggc
gtcccgctgtggatcattatcctagccatcctcgttggcctcctgctcctaggtctgctc
atctatatcctctacaagctcggattcttcaaacgctccctcccatacggcaccgccatg
gaaaaagctcaactcaagccacctgccacctctgatgcctga

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