Canis lupus familiaris (dog): 486915
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Entry
486915 CDS
T01007
Symbol
GRK5
Name
(RefSeq) G protein-coupled receptor kinase 5 isoform X1
KO
K08291
G protein-coupled receptor kinase [EC:
2.7.11.16
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04062
Chemokine signaling pathway
cfa04144
Endocytosis
cfa05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
486915 (GRK5)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
486915 (GRK5)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
486915 (GRK5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
486915 (GRK5)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.16 G-protein-coupled receptor kinase
486915 (GRK5)
Protein kinases [BR:
cfa01001
]
Serine/threonine kinases: AGC group
GRK family [OT]
486915 (GRK5)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RGS
Kinase-like
Pkinase_fungal
Sulfakinin
Motif
Other DBs
NCBI-GeneID:
486915
NCBI-ProteinID:
XP_013964379
Ensembl:
ENSCAFG00000012129
VGNC:
41505
UniProt:
A0A8I3RZ73
A0A8P0SZL5
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Position
28:29566413..29778694
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AA seq
611 aa
AA seq
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MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFVAQ
VGQDLVSQTEKKLLQRPSKELFSACAQSVHDYLKGEPFHEYLDSMYFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFDEERALFYAAEILCGLE
DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEETYSQKFSEEAKSIC
KMLLTKDAKQRLGCREEGAAEVKRHPFFRNMNFKRLEAGMLDPPFIPDPRAVYCKDVLDI
EQFSTVKGVNLDHTDDDFYSKFSTGSVPIPWQSEMIETECFKELNVFGPNGTLSPDLNRS
HPPEPPKKGLLQRIFKRQVRDAPSVPGCPGVGPGMPQAQHQNNSKSSPNPKTSFNHHINS
NHVSSNSTGSS
NT seq
1836 nt
NT seq
+upstream
nt +downstream
nt
atggagctggaaaacatcgtggccaacacggtcttgctgaaagccagggaagggggtgga
ggaaagcgcaaggggaaaagcaagaagtggaaggaaatcctgaagtttcctcacattagc
cagtgtgaagacctccgaaggaccatagacagagattactgcagtttatgtgacaagcag
ccaattgggaggctgcttttccggcagttctgtgaaaccagacctgggctggagtgttac
attcagttcctggactcagtggcagaatatgaagttactccagatgaaaaactgggggaa
aaagggaaggaaattatgaccaagtacctcaccccgaagtcccccgttttcgttgcccag
gttggccaggacctggtctcccagacggagaagaagctcctgcagaggccctccaaggaa
ctcttctctgcctgtgcgcagtctgtccacgactacctgaagggagagcccttccatgag
tatctggacagtatgtattttgatcgctttctccagtggaagtggttggaaaggcaaccg
gtaaccaaaaacactttcaggcagtaccgagtactaggcaaagggggctttggggaggtc
tgtgcctgccaggttcgagccacggggaaaatgtatgcctgcaaacgcttggagaagaag
aggatcaaaaagaggaaaggggaatccatggcacttaacgagaagcagatcctggagaag
gtcaacagccagtttgtggtcaacctggcctatgcctacgagaccaaggacgcgctctgc
ttggttctgaccatcatgaacgggggtgacctgaagttccacatctacaacatgggtaac
cctggctttgacgaggagcgagccttgttttacgcggcagagattctctgcggcttagaa
gacctccaccgggagaacaccgtgtacagagatttgaaacccgaaaatatcctgctagac
gattatggccacattcggatctcagacctgggtctggccgtgaagatccccgagggagac
ctgatccgcggccgggtgggcacggtcggctacatggctccggaggtcctgaacaaccag
agatacggcctgagccctgactactggggtctgggctgcctcatctatgagatgatcgag
gggcagtcaccattccggggccgcaaagagaaggtgaagcgggaagaagtggaccgccgg
gtcctggagacagaggagacctactcccagaagttctctgaggaggccaagtccatctgc
aaaatgctgctcaccaaagatgcaaagcagagactgggctgccgggaggagggggctgcg
gaggtcaagagacaccccttcttcaggaacatgaatttcaagcgcttagaagccgggatg
ttggaccctcccttcattccagacccccgcgccgtgtactgcaaggacgtgctggacatc
gagcagttctccaccgtgaaaggcgtcaacctggaccacacggacgatgacttctattcc
aagttctccacgggctccgtgcccatcccctggcagagcgagatgatagaaaccgagtgc
tttaaggagctgaacgtgtttggacctaacggtaccctctcaccggacctgaacagaagt
caccctccagaaccgccaaagaaagggctgctccagagaatcttcaagcgtcaggtgagg
gacgccccctccgtgcccggctgtcccggcgtcggccccgggatgccccaggcccagcat
caaaacaattccaagagttcacccaatcccaagaccagttttaaccaccacataaattca
aaccatgtcagttcaaactccaccgggagcagctag
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