KEGG   Canis lupus familiaris (dog): 487309
Entry
487309            CDS       T01007                                 
Symbol
HDAC1
Name
(RefSeq) histone deacetylase 1 isoform X1
  KO
K06067  histone deacetylase 1/2 [EC:3.5.1.98]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa03082  ATP-dependent chromatin remodeling
cfa03083  Polycomb repressive complex
cfa04110  Cell cycle
cfa04213  Longevity regulating pathway - multiple species
cfa04330  Notch signaling pathway
cfa04350  TGF-beta signaling pathway
cfa04613  Neutrophil extracellular trap formation
cfa04919  Thyroid hormone signaling pathway
cfa05016  Huntington disease
cfa05031  Amphetamine addiction
cfa05034  Alcoholism
cfa05165  Human papillomavirus infection
cfa05169  Epstein-Barr virus infection
cfa05200  Pathways in cancer
cfa05202  Transcriptional misregulation in cancer
cfa05203  Viral carcinogenesis
cfa05206  MicroRNAs in cancer
cfa05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    487309 (HDAC1)
   03083 Polycomb repressive complex
    487309 (HDAC1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    487309 (HDAC1)
   04350 TGF-beta signaling pathway
    487309 (HDAC1)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    487309 (HDAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    487309 (HDAC1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    487309 (HDAC1)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    487309 (HDAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    487309 (HDAC1)
   05202 Transcriptional misregulation in cancer
    487309 (HDAC1)
   05206 MicroRNAs in cancer
    487309 (HDAC1)
   05203 Viral carcinogenesis
    487309 (HDAC1)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    487309 (HDAC1)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    487309 (HDAC1)
   05165 Human papillomavirus infection
    487309 (HDAC1)
  09164 Neurodegenerative disease
   05016 Huntington disease
    487309 (HDAC1)
  09165 Substance dependence
   05031 Amphetamine addiction
    487309 (HDAC1)
   05034 Alcoholism
    487309 (HDAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cfa03036]
    487309 (HDAC1)
Enzymes [BR:cfa01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     487309 (HDAC1)
Chromosome and associated proteins [BR:cfa03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     487309 (HDAC1)
   HDAC complexes
    Sin3A-HDAC complex
     487309 (HDAC1)
    BRAF-HDAC complex
     487309 (HDAC1)
    REST complex
     487309 (HDAC1)
    SHIP complex
     487309 (HDAC1)
    MiDAC complex
     487309 (HDAC1)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     487309 (HDAC1)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    487309 (HDAC1)
  Chromatin remodeling factors
   NuRD complex
    487309 (HDAC1)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 487309
NCBI-ProteinID: XP_022267756
Ensembl: ENSCAFG00000010597
VGNC: 50625
LinkDB
Position
2:complement(65482127..65517259)
AA seq 521 aa
MVRSPGSSPTPLSQTLVQAQGALGCLSGLPLPPAEFRAVPARADWLEPCPGCAAIGDVGN
YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRP
DNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHH
AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY
GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQC
GSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALD
TEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQM
QVIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEFSDSDEEGEGGRKNSSNFKKAK
RVKTEDEKEKDPEEKKEVTEEEKTKEEKQEAKGVKEEVKLA
NT seq 1566 nt   +upstreamnt  +downstreamnt
atggtacggtccccgggcagctcccccacccccctgtcgcagaccttggtacaggcccag
ggggccctcggctgcctctcagggctgcccttgccccctgccgagttccgggccgtccct
gcgcgagctgattggctggagccgtgcccgggctgcgcggctataggggatgttggaaat
tactattatggacaaggccacccaatgaagcctcaccgaatccgtatgactcacaatttg
ctacttaactatggtctctaccgaaaaatggaaatctatcgccctcacaaagccaatgcc
gaggagatgaccaagtaccacagtgatgactacattaaattcttgcgctccatccgccca
gataacatgtccgagtacagtaagcagatgcagagattcaacgtcggtgaggactgtcca
gtatttgatggcctgtttgaattctgtcagttatctactggtggctctgtggcgagtgct
gtgaaattgaataagcagcagacagacatcgctgtgaattgggccggggggctgcaccat
gcaaagaagtctgaggcatctggcttctgttacgtcaatgatatcgtcttggccatcctg
gaactgctaaagtatcaccagagggtgctgtatattgacattgatattcaccacggcgat
ggcgtggaagaggccttctataccacagaccgggtcatgactgtgtcctttcataaatac
ggagagtacttcccaggaactggggacctacgggatattggggctggcaaaggcaagtat
tatgctgttaactacccgctccgagatgggatcgatgacgagtcctatgaggccattttc
aagccggtcatgtccaaagtgatggagatgttccagcccagtgcggtggtcttacagtgt
ggctctgactccctgtctggggatcggttaggttgcttcaatctcacgatcaaagggcac
gccaagtgtgtggagtttgtgaagagcttcaacctgcctatgctgatgctgggaggaggc
ggctacaccatccgtaatgtggcccgctgctggacatatgaaacagctgtggccctggac
acggaaatcccgaatgagcttccgtacaatgactactttgaatactttggaccagatttc
aaacttcacatcagtccttccaatatgaccaaccagaataccaatgaatacctggagaag
atcaaacagcgactgtttgagaacctgagaatgctgccccacgcacctggggtccaaatg
caggtgattcctgaggatgccattccagaggagagtggcgacgaggacgaagaagaccct
gacaagcgcatctctatctgttcatctgacaaacgaattgcctgtgaggaagagttctcg
gactctgatgaggagggagaaggtggtcgtaagaactcttccaacttcaaaaaagccaag
agagtcaaaactgaggacgaaaaagagaaagacccagaagagaagaaagaagtcacagaa
gaggagaaaaccaaggaggagaagcaagaagccaaaggggtcaaggaggaggtcaagttg
gcctga

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