Canis lupus familiaris (dog): 487514
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Entry
487514 CDS
T01007
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon isoform X1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00564
Glycerophospholipid metabolism
cfa00565
Ether lipid metabolism
cfa00590
Arachidonic acid metabolism
cfa00591
Linoleic acid metabolism
cfa00592
alpha-Linolenic acid metabolism
cfa01100
Metabolic pathways
cfa04010
MAPK signaling pathway
cfa04014
Ras signaling pathway
cfa04072
Phospholipase D signaling pathway
cfa04217
Necroptosis
cfa04270
Vascular smooth muscle contraction
cfa04370
VEGF signaling pathway
cfa04611
Platelet activation
cfa04664
Fc epsilon RI signaling pathway
cfa04666
Fc gamma R-mediated phagocytosis
cfa04724
Glutamatergic synapse
cfa04726
Serotonergic synapse
cfa04730
Long-term depression
cfa04750
Inflammatory mediator regulation of TRP channels
cfa04912
GnRH signaling pathway
cfa04913
Ovarian steroidogenesis
cfa04921
Oxytocin signaling pathway
cfa05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
487514 (PLA2G4E)
00565 Ether lipid metabolism
487514 (PLA2G4E)
00590 Arachidonic acid metabolism
487514 (PLA2G4E)
00591 Linoleic acid metabolism
487514 (PLA2G4E)
00592 alpha-Linolenic acid metabolism
487514 (PLA2G4E)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
487514 (PLA2G4E)
04014 Ras signaling pathway
487514 (PLA2G4E)
04370 VEGF signaling pathway
487514 (PLA2G4E)
04072 Phospholipase D signaling pathway
487514 (PLA2G4E)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
487514 (PLA2G4E)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
487514 (PLA2G4E)
04664 Fc epsilon RI signaling pathway
487514 (PLA2G4E)
04666 Fc gamma R-mediated phagocytosis
487514 (PLA2G4E)
09152 Endocrine system
04912 GnRH signaling pathway
487514 (PLA2G4E)
04913 Ovarian steroidogenesis
487514 (PLA2G4E)
04921 Oxytocin signaling pathway
487514 (PLA2G4E)
09153 Circulatory system
04270 Vascular smooth muscle contraction
487514 (PLA2G4E)
09156 Nervous system
04724 Glutamatergic synapse
487514 (PLA2G4E)
04726 Serotonergic synapse
487514 (PLA2G4E)
04730 Long-term depression
487514 (PLA2G4E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
487514 (PLA2G4E)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
487514 (PLA2G4E)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
487514 (PLA2G4E)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
487514
NCBI-ProteinID:
XP_038317387
Ensembl:
ENSCAFG00000024908
VGNC:
44628
LinkDB
All DBs
Position
30:complement(9076973..9135690)
Genome browser
AA seq
969 aa
AA seq
DB search
MSRCLTVKDQPQLHKGCPEPQRGDTARMTLQSSGGCPGLGTDAFIPQSPQEAEEEGRSER
NVSEFEHTQDLETPNLPPLLPMALWGSQGTVVLWVGLPTIAIVLPSQSSALIASLSCSET
IYGSSLPTDWRAATMLQKQMPAWLSHYLPDLCQAEDGKPSAPCALEGGLSPCHLLTVKVI
RMTNVRQADMVSQTDCFVSLWLPTASRERLRTRTISNCPNPEWNETFSFQIQSQVKNVLE
LSVCDEDTLTPDDHLLTILYDLTKLCFRKKTHVKFPLNPEGMEELEVEFLLEESPSPPES
LITNGVLVARQVSCLEVHTECRQQKKSSKMKDLLVTVKESFEHTQRVSHCREPCCPNPAC
FHYPKYFQPWMHTEVPKSQWSHGLCCCCAHKKSSLVCQPLDCLPDGQTVTLPVGENCALH
MKTTPCPQTLDVRLGFSLCAAELEFLQKRKVVAAQALKQVLQLEEDLHVDEVPLIAIMAT
GGGTRSMTAMYGHLLALQKLNILNCASYITGLSGATWTMATLYRDPDWSSKNLEPAVLEA
RRHVVKDKMPALFPDQLSKFQEELRQRSQEGYKVTFTDFWGLLIEACLGDERNESKLSDQ
RAALSQGQNPLPIYLTINVKDDVSNQDFREWCEFSPYEVGLQKYGAFIPTELFGSKFFMG
RLMKRIPESRMCYMLGLWSSIFSLNLLDAWNLSQSSEEFFHRWTRERVHDIEDEPLLPEI
PKCDANVLDTAVVIPGSWLSNTFRSILTHRAFVSQFHNFLLGLQLHTDYLQNSQFSIWRD
TVLDGFPNQLTESVNHLCLLDTAFFVNSSYPPLLRPERKVDLIIHLNYCAGSQTKPMKQT
CEYCTMQNIPFPKYELQEEEDNLKECYLMENSQEPDAPIVIFFPLINDTFQKYKAPGVER
SPEELEQGHVDIYGPQTPYATKELTYTEAAFDKLVKLSEYNILNNKDKLLQALRLAVERK
KRPKSQCPS
NT seq
2910 nt
NT seq
+upstream
nt +downstream
nt
atgtccagatgcctcactgtgaaggaccagcctcagctccacaagggctgtcctgagccc
cagagaggggacacagccagaatgactctccagagctcgggaggctgtcctggcctggga
actgatgcgttcattccacagagcccacaagaggcagaagaagaaggcaggtcagaaaga
aatgtcagtgagtttgagcatacacaggacctggagactcctaatctcccacctctgctt
ccgatggccctttggggctctcagggcactgtagtgctgtgggttgggctgcccacaata
gcaatagtgttgccttcgcaaagttcagctctgattgcatcgctctcatgctcagaaacc
atctatggctcttcattgcctacagactggagagctgccacgatgctccagaagcagatg
cctgcctggctctcccactacctaccagacctatgccaagcagaagatggcaagccttca
gccccctgtgccttggagggtgggctgtctccatgccatctcctgaccgtgaaggtcatc
cggatgacaaatgtccgacaggctgatatggtgagccagacagactgctttgtgagcctc
tggctgcctaccgcttctcgtgagaggctgaggactaggaccatctccaactgcccaaac
ccagagtggaatgaaaccttcagcttccagatccagagccaagtgaagaatgtgctagag
ctgagcgtctgtgatgaagacacactgacaccagatgaccatctcttgacaattctctat
gacctcaccaaactctgcttccgaaagaaaacccatgtgaagttcccactcaacccagag
ggcatggaagagctggaggtagagttcttgctggaggagagtccctctccacctgagtcc
ctcatcaccaatggtgtgctggtggctcgtcaagtctcctgcctagaggttcacacagaa
tgcaggcagcagaagaagagcagcaaaatgaaggacctcctggtgacagtgaaggagtcc
ttcgagcacacccaacgcgtctcacactgccgggagccgtgctgcccaaacccggcctgc
ttccactaccccaaatacttccagccctggatgcacacggaagtgcccaagagccagtgg
agccatgggctttgctgctgctgtgcacacaagaagagcagccttgtctgccagcccctt
gattgcctccctgatggccagacggtgaccctgccagtgggtgagaactgcgcattacac
atgaagactacaccctgccctcagacgctggatgtgcggctgggcttcagcctgtgtgca
gcagagctggagttcctgcagaagcggaaggtggtggcggctcaggcactgaaacaggtg
ctgcagctggaggaggacctgcatgtggatgaggtaccactgatagccatcatggccact
gggggtggaacaagatccatgaccgccatgtatggccacctgttggcgctgcagaagctg
aacatcctgaactgtgccagctacatcacaggcctgtcaggggccacctggaccatggct
accttgtaccgtgaccccgactggtcctccaaaaatctggagcctgccgtacttgaggca
cggaggcatgtggtcaaggacaagatgcctgccctgttcccagaccagctctccaaattc
caggaggagcttcggcagcgcagtcaggaaggctacaaggtcacctttacagatttctgg
ggcctgctgattgaggcctgtctgggggatgagagaaatgaatccaaactatcagatcag
cgtgctgctttgagccaaggccagaaccccctgcccatctacctcaccatcaatgtcaag
gatgatgtaagcaaccaggatttcagagagtggtgcgagttctctccctacgaggtgggc
ctgcagaagtatggggccttcatccccacagagctcttcggctccaagttcttcatgggg
cggcttatgaagaggatcccagagtcgcggatgtgctacatgctaggcttgtggagcagc
atcttctccctaaacctgcttgatgcctggaatctgtcccaaagctcggaggagtttttc
cacaggtggacgagggagagagtgcacgacatcgaagatgagccactcctgcctgaaatt
cccaaatgtgatgccaacgtcttggacactgcggtggtgatcccagggtcatggctgtcc
aatactttccgcagcatcctcacccatcgggcctttgtgtctcagttccacaacttcttg
ttgggactgcagctgcacacggactatctccagaacagccagttctccatatggagagac
acagtgctagatggtttcccgaaccagctgacagagtccgtgaaccacttgtgcctgttg
gacactgcattcttcgtcaactccagctacccgcccctcctcaggccagagagaaaagtt
gacctcatcattcacctcaattactgcgctgggtcccagacaaagcccatgaagcaaaca
tgtgagtactgcaccatgcagaacatccccttccccaaatacgagctgcaggaggaggaa
gacaacctcaaggagtgctacttgatggagaactcccaggaaccagatgcccccattgtg
attttcttcccactcatcaatgacaccttccagaagtacaaggccccaggtgtggagcga
agccctgaggagctggaacagggtcacgtggacatttatggccctcaaactccatatgct
accaaggagttgacatacacagaggctgcctttgacaagctggtgaagctctctgagtac
aacatcctgaataacaaggacaagctccttcaggccttgaggctggcggtggagaggaag
aaacgcccaaagagccagtgtccatcctaa
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